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Items: 1 to 50 of 271

1.

Novel Survivin Inhibitor for Suppressing Pancreatic Cancer Cells Growth via Downregulating Sp1 and Sp3 Transcription Factors.

Hurtado M, Sankpal UT, Kaba A, Mahammad S, Chhabra J, Brown DT, Gurung RK, Holder AA, Vishwanatha JK, Basha R.

Cell Physiol Biochem. 2018;51(4):1894-1907. doi: 10.1159/000495715. Epub 2018 Nov 30.

2.

Role of the vacuolar ATPase in the Alphavirus replication cycle.

Schuchman RM, Vancini R, Piper A, Breuer D, Ribeiro M, Ferreira D, Magliocca J, Emmerich V, Hernandez R, Brown DT.

Heliyon. 2018 Jul 25;4(7):e00701. doi: 10.1016/j.heliyon.2018.e00701. eCollection 2018 Jul.

3.

Copper-tolfenamic acid: evaluation of stability and anti-cancer activity.

Hurtado M, Sankpal UT, Chhabra J, Brown DT, Maram R, Patel R, Gurung RK, Simecka J, Holder AA, Basha R.

Invest New Drugs. 2019 Feb;37(1):27-34. doi: 10.1007/s10637-018-0594-9. Epub 2018 May 15.

PMID:
29761244
4.

RedUSe: reducing antipsychotic and benzodiazepine prescribing in residential aged care facilities.

Westbury JL, Gee P, Ling T, Brown DT, Franks KH, Bindoff I, Bindoff A, Peterson GM.

Med J Aust. 2018 May 21;208(9):398-403. Epub 2018 May 14.

PMID:
29747564
5.

PARP1-dependent eviction of the linker histone H1 mediates immediate early gene expression during neuronal activation.

Azad GK, Ito K, Sailaja BS, Biran A, Nissim-Rafinia M, Yamada Y, Brown DT, Takizawa T, Meshorer E.

J Cell Biol. 2018 Feb 5;217(2):473-481. doi: 10.1083/jcb.201703141. Epub 2017 Dec 28.

6.

Prosthodontic Rehabilitation for a Patient with Down Syndrome: A Clinical Report.

Alqahtani NM, Alsayed HD, Levon JA, Brown DT.

J Prosthodont. 2018 Oct;27(8):681-687. doi: 10.1111/jopr.12595. Epub 2017 Jan 24.

PMID:
28118512
7.

Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.

Chinthalapudi K, Rangarajan ES, Brown DT, Izard T.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9539-44. doi: 10.1073/pnas.1600702113. Epub 2016 Aug 8.

8.

Single-Site Glycoprotein Mutants Inhibit a Late Event in Sindbis Virus Assembly.

Magliocca J, Vancini R, Hernandez R, Brown DT.

J Virol. 2016 Aug 26;90(18):8372-80. doi: 10.1128/JVI.00948-16. Print 2016 Sep 15.

9.
10.

Mechanisms and Functions of Vinculin Interactions with Phospholipids at Cell Adhesion Sites.

Izard T, Brown DT.

J Biol Chem. 2016 Feb 5;291(6):2548-55. doi: 10.1074/jbc.R115.686493. Epub 2016 Jan 4. Review.

11.

Molecular dynamics of histone H1.

Flanagan TW, Brown DT.

Biochim Biophys Acta. 2016 Mar;1859(3):468-75. doi: 10.1016/j.bbagrm.2015.10.005. Epub 2015 Oct 8. Review.

12.

Vinculin-cell membrane interactions.

Brown DT, Izard T.

Oncotarget. 2015 Oct 27;6(33):34043-4. doi: 10.18632/oncotarget.5868. No abstract available.

13.

Sleep and agitation in nursing home residents with and without dementia.

Brown DT, Westbury JL, Schüz B.

Int Psychogeriatr. 2015 Dec;27(12):1945-55. doi: 10.1017/S1041610215001568. Epub 2015 Oct 2.

PMID:
26424155
14.

Lipid binding promotes oligomerization and focal adhesion activity of vinculin.

Chinthalapudi K, Rangarajan ES, Patil DN, George EM, Brown DT, Izard T.

J Cell Biol. 2014 Dec 8;207(5):643-56. doi: 10.1083/jcb.201404128.

15.

Structural differences observed in arboviruses of the alphavirus and flavivirus genera.

Hernandez R, Brown DT, Paredes A.

Adv Virol. 2014;2014:259382. doi: 10.1155/2014/259382. Epub 2014 Sep 16. Review.

16.

Do older individuals have difficulty processing motion or excluding noise? Implications for safe driving.

Conlon EG, Brown DT, Power GF, Bradbury SA.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2015;22(3):322-39. doi: 10.1080/13825585.2014.939939. Epub 2014 Jul 28.

PMID:
25066200
17.

Live attenuated tetravalent dengue virus host range vaccine is immunogenic in African green monkeys following a single vaccination.

Briggs CM, Smith KM, Piper A, Huitt E, Spears CJ, Quiles M, Ribeiro M, Thomas ME, Brown DT, Hernandez R.

J Virol. 2014 Jun;88(12):6729-42. doi: 10.1128/JVI.00541-14. Epub 2014 Apr 2.

18.

Chikungunya virus host range E2 transmembrane deletion mutants induce protective immunity against challenge in C57BL/6J mice.

Piper A, Ribeiro M, Smith KM, Briggs CM, Huitt E, Nanda K, Spears CJ, Quiles M, Cullen J, Thomas ME, Brown DT, Hernandez R.

J Virol. 2013 Jun;87(12):6748-57. doi: 10.1128/JVI.03357-12. Epub 2013 Apr 3.

19.

Alphavirus genome delivery occurs directly at the plasma membrane in a time- and temperature-dependent process.

Vancini R, Wang G, Ferreira D, Hernandez R, Brown DT.

J Virol. 2013 Apr;87(8):4352-9. doi: 10.1128/JVI.03412-12. Epub 2013 Feb 6.

20.

A high-throughput screening campaign for detection of ca(2+)-activated k(+) channel activators and inhibitors using a fluorometric imaging plate reader-based tl(+)-influx assay.

Jørgensen S, Dyhring T, Brown DT, Strøbæk D, Christophersen P, Demnitz J.

Assay Drug Dev Technol. 2013 Apr;11(3):163-72. doi: 10.1089/adt.2012.479. Epub 2012 Nov 30.

PMID:
23198866
21.

The battle of the bonds.

Platt JA, Reifeis PE, MacPherson ME, Willis LH, Kirkup ML, Rhodes B, Brown DT.

J Indiana Dent Assoc. 2012 Summer;91(2):20-2. No abstract available.

PMID:
23155889
22.

Positive allosteric modulation of GABA-A receptors reduces capsaicin-induced primary and secondary hypersensitivity in rats.

Hansen RR, Erichsen HK, Brown DT, Mirza NR, Munro G.

Neuropharmacology. 2012 Dec;63(8):1360-7. doi: 10.1016/j.neuropharm.2012.08.002. Epub 2012 Aug 17.

PMID:
22985969
23.

NS6180, a new K(Ca) 3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease.

Strøbæk D, Brown DT, Jenkins DP, Chen YJ, Coleman N, Ando Y, Chiu P, Jørgensen S, Demnitz J, Wulff H, Christophersen P.

Br J Pharmacol. 2013 Jan;168(2):432-44. doi: 10.1111/j.1476-5381.2012.02143.x.

24.

Testing of novel dengue virus 2 vaccines in African green monkeys: safety, immunogenicity, and efficacy.

Smith KM, Nanda K, Spears CJ, Piper A, Ribeiro M, Quiles M, Briggs CM, Thomas GS, Thomas ME, Brown DT, Hernandez R, McCarl V.

Am J Trop Med Hyg. 2012 Oct;87(4):743-753. doi: 10.4269/ajtmh.2012.12-0004. Epub 2012 Aug 13.

25.

Effect of surface treatments on microtensile bond strength of repaired aged silorane resin composite.

Palasuk J, Platt JA, Cho SD, Levon JA, Brown DT, Hovijitra ST.

Oper Dent. 2013 Jan-Feb;38(1):91-9. doi: 10.2341/11-057-L. Epub 2012 Jul 25.

PMID:
22830537
26.

N- and C-terminal domains determine differential nucleosomal binding geometry and affinity of linker histone isotypes H1(0) and H1c.

Vyas P, Brown DT.

J Biol Chem. 2012 Apr 6;287(15):11778-87. doi: 10.1074/jbc.M111.312819. Epub 2012 Feb 10.

27.

Infection of cells by alphaviruses.

Brown DT, Hernandez R.

Adv Exp Med Biol. 2012;726:181-99. doi: 10.1007/978-1-4614-0980-9_8. Review.

PMID:
22297514
28.

Conformational changes in Sindbis virus induced by decreased pH are revealed by small-angle neutron scattering.

He L, Piper A, Meilleur F, Hernandez R, Heller WT, Brown DT.

J Virol. 2012 Feb;86(4):1982-7. doi: 10.1128/JVI.06569-11. Epub 2011 Dec 7.

29.

An alternative pathway for alphavirus entry.

Kononchik JP Jr, Hernandez R, Brown DT.

Virol J. 2011 Jun 15;8:304. doi: 10.1186/1743-422X-8-304. Review.

30.

Structural mutants of dengue virus 2 transmembrane domains exhibit host-range phenotype.

Smith KM, Nanda K, Spears CJ, Ribeiro M, Vancini R, Piper A, Thomas GS, Thomas ME, Brown DT, Hernandez R.

Virol J. 2011 Jun 9;8:289. doi: 10.1186/1743-422X-8-289.

31.

Variation in antibiotic-induced microbial recolonization impacts on the host metabolic phenotypes of rats.

Swann JR, Tuohy KM, Lindfors P, Brown DT, Gibson GR, Wilson ID, Sidaway J, Nicholson JK, Holmes E.

J Proteome Res. 2011 Aug 5;10(8):3590-603. doi: 10.1021/pr200243t. Epub 2011 Jun 29.

32.

Alphavirus adsorption to mosquito cells as viewed by freeze fracture immunolabeling.

Kononchik JP, Vancini R, Brown DT.

Virology. 2011 Jul 5;415(2):132-40. doi: 10.1016/j.virol.2011.04.011. Epub 2011 May 10.

33.
34.

Role of the vacuolar-ATPase in Sindbis virus infection.

Hunt SR, Hernandez R, Brown DT.

J Virol. 2011 Feb;85(3):1257-66. doi: 10.1128/JVI.01864-10. Epub 2010 Nov 17.

35.

Nucleosome interaction surface of linker histone H1c is distinct from that of H1(0).

George EM, Izard T, Anderson SD, Brown DT.

J Biol Chem. 2010 Jul 2;285(27):20891-6. doi: 10.1074/jbc.M110.108639. Epub 2010 May 5.

36.

Growth and maintenance of baby hamster kidney (BHK) cells.

Hernandez R, Brown DT.

Curr Protoc Microbiol. 2010 May;Chapter 4:Appendix 4H. doi: 10.1002/9780471729259.mca04hs17.

PMID:
20440683
37.

Growth and maintenance of mosquito cell lines.

Hernandez R, Brown DT.

Curr Protoc Microbiol. 2010 May;Appendix 4:4J. doi: 10.1002/9780471729259.mca04js17.

PMID:
20440680
38.

Growth and maintenance of chick embryo fibroblasts (CEF).

Hernandez R, Brown DT.

Curr Protoc Microbiol. 2010 May;Appendix 4:4I. doi: 10.1002/9780471729259.mca04is17.

PMID:
20440679
39.

Prothymosin alpha is a component of a linker histone chaperone.

George EM, Brown DT.

FEBS Lett. 2010 Jul 2;584(13):2833-6. doi: 10.1016/j.febslet.2010.04.065. Epub 2010 Apr 29.

40.

Dissecting the binding mechanism of the linker histone in live cells: an integrated FRAP analysis.

Stasevich TJ, Mueller F, Brown DT, McNally JG.

EMBO J. 2010 Apr 7;29(7):1225-34. doi: 10.1038/emboj.2010.24. Epub 2010 Mar 11.

41.

The structure of Sindbis virus produced from vertebrate and invertebrate hosts as determined by small-angle neutron scattering.

He L, Piper A, Meilleur F, Myles DA, Hernandez R, Brown DT, Heller WT.

J Virol. 2010 May;84(10):5270-6. doi: 10.1128/JVI.00044-10. Epub 2010 Mar 10.

42.

Insect response to alphavirus infection--establishment of alphavirus persistence in insect cells involves inhibition of viral polyprotein cleavage.

Mudiganti U, Hernandez R, Brown DT.

Virus Res. 2010 Jun;150(1-2):73-84. doi: 10.1016/j.virusres.2010.02.016. Epub 2010 Mar 7.

PMID:
20214937
43.

Sindbis virus: propagation, quantification, and storage.

Hernandez R, Sinodis C, Brown DT.

Curr Protoc Microbiol. 2010 Feb;Chapter 15:Unit15B.1. doi: 10.1002/9780471729259.mc15b01s16.

PMID:
20131223
44.

Differential incorporation of cholesterol by Sindbis virus grown in mammalian or insect cells.

Hafer A, Whittlesey R, Brown DT, Hernandez R.

J Virol. 2009 Sep;83(18):9113-21. doi: 10.1128/JVI.00755-09. Epub 2009 Jul 8.

45.

A high capacity Alphavirus heterologous gene delivery system.

Nanda K, Vancini R, Ribeiro M, Brown DT, Hernandez R.

Virology. 2009 Aug 1;390(2):368-73. doi: 10.1016/j.virol.2009.05.026. Epub 2009 Jun 16.

46.

Helical virus particles formed from morphological subunits of a membrane containing icosahedral virus.

Kononchik JP Jr, Nelson S, Hernandez R, Brown DT.

Virology. 2009 Mar 15;385(2):285-93. doi: 10.1016/j.virol.2008.12.015. Epub 2009 Jan 14.

47.

Sindbis virus: propagation, quantification, and storage.

Hernandez R, Sinodis C, Brown DT.

Curr Protoc Microbiol. 2005 Oct;Chapter 15:Unit 15B.1. doi: 10.1002/9780471729259.mc15b01s00.

PMID:
18770557
48.

Sindbis virus conformational changes induced by a neutralizing anti-E1 monoclonal antibody.

Hernandez R, Paredes A, Brown DT.

J Virol. 2008 Jun;82(12):5750-60. doi: 10.1128/JVI.02673-07. Epub 2008 Apr 16.

49.

Location and role of free cysteinyl residues in the Sindbis virus E1 and E2 glycoproteins.

Whitehurst CB, Soderblom EJ, West ML, Hernandez R, Goshe MB, Brown DT.

J Virol. 2007 Jun;81(12):6231-40. Epub 2007 Apr 4.

50.

Infection of cells by Sindbis virus at low temperature.

Wang G, Hernandez R, Weninger K, Brown DT.

Virology. 2007 Jun 5;362(2):461-7. Epub 2007 Feb 6.

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