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Items: 1 to 50 of 696

1.

New missense variants in RELT causing hypomineralised amelogenesis imperfecta.

Nikolopoulos G, Smith CEL, Brookes SJ, El-Asrag ME, Brown CJ, Patel A, Murillo G, O'Connell MJ, Inglehearn CF, Mighell AJ.

Clin Genet. 2020 Feb 12. doi: 10.1111/cge.13721. [Epub ahead of print]

PMID:
32052416
2.

Melting of Hemoglobin in Native Solutions as measured by IMS-MS.

Woodall DW, Brown CJ, Raab SA, El-Baba TJ, Laganowsky A, Russell DH, Clemmer DE.

Anal Chem. 2020 Feb 7. doi: 10.1021/acs.analchem.9b05561. [Epub ahead of print]

PMID:
31990187
3.

Characterizing Thermal Transitions of IgG with Mass Spectrometry.

Brown CJ, Woodall DW, El-Baba TJ, Clemmer DE.

J Am Soc Mass Spectrom. 2019 Nov 1;30(11):2438-2445.

PMID:
31944736
4.

Decline of coastal apex shark populations over the past half century.

Roff G, Brown CJ, Priest MA, Mumby PJ.

Commun Biol. 2018 Dec 13;1(1):223. doi: 10.1038/s42003-018-0233-1.

PMID:
31924869
5.

End-of-Life Spending and Healthcare Utilization Among Older Adults with Chronic Obstructive Pulmonary Disease.

Iyer AS, Goodrich CA, Dransfield MT, Alam SS, Brown CJ, Landefeld CS, Bakitas MA, Brown JR.

Am J Med. 2019 Dec 26. pii: S0002-9343(19)31105-2. doi: 10.1016/j.amjmed.2019.11.024. [Epub ahead of print]

PMID:
31883772
6.

Rigorous Computational and Experimental Investigations on MDM2/MDMX-Targeted Linear and Macrocyclic Peptides.

Diller DJ, Swanson J, Bayden AS, Brown CJ, Thean D, Lane DP, Partridge AW, Sawyer TK, Audie J.

Molecules. 2019 Dec 14;24(24). pii: E4586. doi: 10.3390/molecules24244586.

7.

Synthesis of Chiral Alkenyl Cyclopropane Amino Acids for Incorporation into Stapled Peptides.

Yuen TY, Brown CJ, Tan YS, Johannes CW.

J Org Chem. 2020 Feb 7;85(3):1556-1566. doi: 10.1021/acs.joc.9b02659. Epub 2019 Dec 26.

PMID:
31825612
8.

Can less be more? Organ preservation strategies in the management of rectal cancer.

Rouleau-Fournier F, Brown CJ.

Curr Oncol. 2019 Nov;26(Suppl 1):S16-S23. doi: 10.3747/co.26.5841. Epub 2019 Nov 1. Review.

9.

Simultaneous measurement of p53:Mdm2 and p53:Mdm4 protein-protein interactions in whole cells using fluorescence labelled foci.

Frosi Y, Inoue K, Ramlan SR, Lane DP, Watanabe T, Brown CJ.

Sci Rep. 2019 Nov 29;9(1):17933. doi: 10.1038/s41598-019-54123-z.

10.

Prevalence of Hospital-Associated Disability in Older Adults: A Meta-analysis.

Loyd C, Markland AD, Zhang Y, Fowler M, Harper S, Wright NC, Carter CS, Buford TW, Smith CH, Kennedy R, Brown CJ.

J Am Med Dir Assoc. 2019 Nov 13. pii: S1525-8610(19)30696-6. doi: 10.1016/j.jamda.2019.09.015. [Epub ahead of print] Review.

PMID:
31734122
11.

Benthic marine debris in the Bay of Fundy, eastern Canada: Spatial distribution and categorization using seafloor video footage.

Goodman AJ, Walker TR, Brown CJ, Wilson BR, Gazzola V, Sameoto JA.

Mar Pollut Bull. 2020 Jan;150:110722. doi: 10.1016/j.marpolbul.2019.110722. Epub 2019 Nov 14.

12.

A Danish version of the life-space assessment (LSA-DK) - translation, content validity and cultural adaptation using cognitive interviewing in older mobility limited adults.

Pedersen MM, Kjær-Sørensen P, Midtgaard J, Brown CJ, Bodilsen AC.

BMC Geriatr. 2019 Nov 15;19(1):312. doi: 10.1186/s12877-019-1347-0.

13.

A Surgeon's Guide to Treating Older Patients with Colorectal Cancer.

Kim S, Lee SC, Skinner CS, Brown CJ, Balentine CJ.

Curr Colorectal Cancer Rep. 2019 Feb;15(1):1-7. doi: 10.1007/s11888-019-00424-4. Epub 2019 Feb 7.

14.

Escape From X-Chromosome Inactivation: An Evolutionary Perspective.

Posynick BJ, Brown CJ.

Front Cell Dev Biol. 2019 Oct 22;7:241. doi: 10.3389/fcell.2019.00241. eCollection 2019. Review.

15.

Impact of stimulus frequency and recording electrode on electrocochleography in Hybrid cochlear implant users.

Tejani VD, Carroll RL, Abbas PJ, Brown CJ.

Hear Res. 2019 Dec;384:107815. doi: 10.1016/j.heares.2019.107815. Epub 2019 Oct 18.

PMID:
31678892
16.

A Qualitative Study of Pulmonary and Palliative Care Clinician Perspectives on Early Palliative Care in Chronic Obstructive Pulmonary Disease.

Iyer AS, Dionne-Odom JN, Khateeb DM, O'Hare L, Tucker RO, Brown CJ, Dransfield MT, Bakitas MA.

J Palliat Med. 2019 Oct 29. doi: 10.1089/jpm.2019.0355. [Epub ahead of print]

PMID:
31657654
17.

The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells.

Mortensen ACL, Spiegelberg D, Brown CJ, Lane DP, Nestor M.

Front Oncol. 2019 Sep 19;9:923. doi: 10.3389/fonc.2019.00923. eCollection 2019.

18.

Predictors of rectal adenoma recurrence following transanal endoscopic surgery: a retrospective cohort study.

Chan T, Karimuddin AA, Raval MJ, Phang PT, Tang V, Brown CJ.

Surg Endosc. 2019 Sep 11. doi: 10.1007/s00464-019-07114-0. [Epub ahead of print]

PMID:
31512037
19.

Beyond sequence homology: Cellular biology limits the potential of XIST to act as a miRNA sponge.

Marshall EA, Stewart GL, Sage AP, Lam WL, Brown CJ.

PLoS One. 2019 Aug 16;14(8):e0221371. doi: 10.1371/journal.pone.0221371. eCollection 2019.

20.

Characterizing Thermal Transitions of IgG with Mass Spectrometry.

Brown CJ, Woodall DW, El-Baba TJ, Clemmer DE.

J Am Soc Mass Spectrom. 2019 Nov;30(11):2438-2445. doi: 10.1007/s13361-019-02292-6. Epub 2019 Jul 30.

PMID:
31363989
21.

Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles.

Yuen TY, Brown CJ, Xue Y, Tan YS, Ferrer Gago FJ, Lee XE, Neo JY, Thean D, Kaan HYK, Partridge AW, Verma CS, Lane DP, Johannes CW.

Chem Sci. 2019 May 30;10(26):6457-6466. doi: 10.1039/c9sc01456j. eCollection 2019 Jul 14.

22.

Prediction model and web-based risk calculator for postoperative ileus after loop ileostomy closure.

Garfinkle R, Filion KB, Bhatnagar S, Sigler G, Banks A, Letarte F, Liberman S, Brown CJ, Boutros M.

Br J Surg. 2019 Nov;106(12):1676-1684. doi: 10.1002/bjs.11235. Epub 2019 Jul 17.

PMID:
31313828
23.

Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties.

Partridge AW, Kaan HYK, Juang YC, Sadruddin A, Lim S, Brown CJ, Ng S, Thean D, Ferrer F, Johannes C, Yuen TY, Kannan S, Aronica P, Tan YS, Pradhan MR, Verma CS, Hochman J, Chen S, Wan H, Ha S, Sherborne B, Lane DP, Sawyer TK.

Molecules. 2019 Jun 20;24(12). pii: E2292. doi: 10.3390/molecules24122292.

24.

Impact of Human Leucocyte Antigen epitope matched platelet transfusions in alloimmunised aplastic anaemia patients.

Kallon D, Navarrete CV, Sage DA, Stanworth S, Mufti GJ, Marsh JCW, Brown CJ.

Transfus Med. 2019 Jun 17. doi: 10.1111/tme.12612. [Epub ahead of print]

PMID:
31209973
25.

endo-Hydroxamic Acid Monomers for the Assembly of a Suite of Non-native Dimeric Macrocyclic Siderophores Using Metal-Templated Synthesis.

Brown CJM, Gotsbacher MP, Holland JP, Codd R.

Inorg Chem. 2019 Oct 21;58(20):13591-13603. doi: 10.1021/acs.inorgchem.9b00878. Epub 2019 Jun 5.

PMID:
31185545
26.

A microdroplet-accelerated Biginelli reaction: mechanisms and separation of isomers using IMS-MS.

Sahota N, AbuSalim DI, Wang ML, Brown CJ, Zhang Z, El-Baba TJ, Cook SP, Clemmer DE.

Chem Sci. 2019 Mar 28;10(18):4822-4827. doi: 10.1039/c9sc00704k. eCollection 2019 May 14.

27.

The Role of Vegetated Coastal Wetlands for Marine Megafauna Conservation.

Sievers M, Brown CJ, Tulloch VJD, Pearson RM, Haig JA, Turschwell MP, Connolly RM.

Trends Ecol Evol. 2019 Sep;34(9):807-817. doi: 10.1016/j.tree.2019.04.004. Epub 2019 May 21. Review.

PMID:
31126633
28.

Monitoring flux in signalling pathways through measurements of 4EBP1-mediated eIF4F complex assembly.

Frosi Y, Usher R, Lian DTG, Lane DP, Brown CJ.

BMC Biol. 2019 May 22;17(1):40. doi: 10.1186/s12915-019-0658-0.

29.

A multi-centre randomized controlled trial of open vs closed management of the rectal defect after transanal endoscopic microsurgery.

Brown CJ, Hochman D, Raval MJ, Moloo H, Phang PT, Bouchard A, Williams L, Drolet S, Boushey R.

Colorectal Dis. 2019 Sep;21(9):1025-1031. doi: 10.1111/codi.14689. Epub 2019 Jun 11.

PMID:
31081281
30.

Vision using multiple distinct rod opsins in deep-sea fishes.

Musilova Z, Cortesi F, Matschiner M, Davies WIL, Patel JS, Stieb SM, de Busserolles F, Malmstrøm M, Tørresen OK, Brown CJ, Mountford JK, Hanel R, Stenkamp DL, Jakobsen KS, Carleton KL, Jentoft S, Marshall J, Salzburger W.

Science. 2019 May 10;364(6440):588-592. doi: 10.1126/science.aav4632.

31.

Comparative genomics of Bifidobacterium species isolated from marmosets and humans.

Brown CJ, Mtui D, Oswald BP, Van Leuven JT, Vallender EJ, Schultz-Darken N, Ross CN, Tardif SD, Austad SN, Forney LJ.

Am J Primatol. 2019 Oct;81(10-11):e983. doi: 10.1002/ajp.22983. Epub 2019 May 6.

32.

Fixation Effects on Variant Calling in a Clinical Resequencing Panel.

Parker JDK, Yap SQ, Starks E, Slind J, Swanson L, Docking TR, Fuller M, Zhou C, Walker B, Filipenko D, Xiong W, Karimuddin AA, Phang PT, Raval M, Brown CJ, Karsan A.

J Mol Diagn. 2019 Jul;21(4):705-717. doi: 10.1016/j.jmoldx.2019.03.005. Epub 2019 May 2.

PMID:
31055024
33.

A Formative Evaluation of Patient and Family Caregiver Perspectives on Early Palliative Care in Chronic Obstructive Pulmonary Disease across Disease Severity.

Iyer AS, Dionne-Odom JN, Ford SM, Crump Tims SL, Sockwell ED, Ivankova NV, Brown CJ, Tucker RO, Dransfield MT, Bakitas MA.

Ann Am Thorac Soc. 2019 Aug;16(8):1024-1033. doi: 10.1513/AnnalsATS.201902-112OC.

PMID:
31039003
34.

Variable-Temperature ESI-IMS-MS Analysis of Myohemerythrin Reveals Ligand Losses, Unfolding, and a Non-Native Disulfide Bond.

Woodall DW, El-Baba TJ, Fuller DR, Liu W, Brown CJ, Laganowsky A, Russell DH, Clemmer DE.

Anal Chem. 2019 May 21;91(10):6808-6814. doi: 10.1021/acs.analchem.9b00981. Epub 2019 May 9.

PMID:
31038926
35.

Age-Related Changes in Temporal Resolution Revisited: Electrophysiological and Behavioral Findings From Cochlear Implant Users.

Mussoi BSS, Brown CJ.

Ear Hear. 2019 Nov/Dec;40(6):1328-1344. doi: 10.1097/AUD.0000000000000732.

PMID:
31033701
36.

Student Experience of Self-Care in an Online Master of Science in Nursing Course.

Brown CJ, Bar B.

Nurs Educ Perspect. 2019 May/Jun;40(3):168-170. doi: 10.1097/01.NEP.0000000000000402.

PMID:
31008885
37.

Dissecting the Components of Sindbis Virus from Arthropod and Vertebrate Hosts: Implications for Infectivity Differences.

Dunbar CA, Rayaprolu V, Wang JC, Brown CJ, Leishman E, Jones-Burrage S, Trinidad JC, Bradshaw HB, Clemmer DE, Mukhopadhyay S, Jarrold MF.

ACS Infect Dis. 2019 Jun 14;5(6):892-902. doi: 10.1021/acsinfecdis.8b00356. Epub 2019 Apr 15.

PMID:
30986033
38.

Avoided emissions and conservation of scrub mangroves: potential for a Blue Carbon project in the Gulf of California, Mexico.

Adame MF, Najera E, Lovelock CE, Brown CJ.

Biol Lett. 2018 Dec 21;14(12):20180400. doi: 10.1098/rsbl.2018.0400.

39.

Proteome changes in the aging Drosophila melanogaster head.

Brown CJ, Kaufman T, Trinidad JC, Clemmer DE.

Int J Mass Spectrom. 2018 Feb;425:36-46. doi: 10.1016/j.ijms.2018.01.003. Epub 2018 Jan 10.

40.

Phenotype and Variant Spectrum in the LAMB3 Form of Amelogenesis Imperfecta.

Smith CEL, Poulter JA, Brookes SJ, Murillo G, Silva S, Brown CJ, Patel A, Hussain H, Kirkham J, Inglehearn CF, Mighell AJ.

J Dent Res. 2019 Jun;98(6):698-704. doi: 10.1177/0022034519835205. Epub 2019 Mar 24.

41.

Structural insights reveal a recognition feature for tailoring hydrocarbon stapled-peptides against the eukaryotic translation initiation factor 4E protein.

Lama D, Liberatore AM, Frosi Y, Nakhle J, Tsomaia N, Bashir T, Lane DP, Brown CJ, Verma CS, Auvin S.

Chem Sci. 2019 Jan 7;10(8):2489-2500. doi: 10.1039/c8sc03759k. eCollection 2019 Feb 28.

42.

Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: Report from the 17th International HLA and Immunogenetics Workshop.

Creary LE, Guerra SG, Chong W, Brown CJ, Turner TR, Robinson J, Bultitude WP, Mayor NP, Marsh SGE, Saito K, Lam K, Duke JL, Mosbruger TL, Ferriola D, Monos D, Willis A, Askar M, Fischer G, Saw CL, Ragoussis J, Petrek M, Serra-Pagés C, Juan M, Stavropoulos-Giokas C, Dinou A, Ameen R, Al Shemmari S, Spierings E, Gendzekhadze K, Morris GP, Zhang Q, Kashi Z, Hsu S, Gangavarapu S, Mallempati KC, Yamamoto F, Osoegawa K, Vayntrub T, Chang CJ, Hansen JA, Fernández-Viňa MA.

Hum Immunol. 2019 Jul;80(7):449-460. doi: 10.1016/j.humimm.2019.03.001. Epub 2019 Mar 4.

43.

Development and evolution of a two-day intensive resident experience in geriatric medicine.

Ford CR, Loyd C, Rothrock AG, Johnson Ii TM, Allman RM, Brown CJ.

Gerontol Geriatr Educ. 2019 Mar 6:1-14. doi: 10.1080/02701960.2019.1587753. [Epub ahead of print]

PMID:
30839246
44.

How do genes that escape from X-chromosome inactivation contribute to Turner syndrome?

Peeters SB, Korecki AJ, Baldry SEL, Yang C, Tosefsky K, Balaton BP, Simpson EM, Brown CJ.

Am J Med Genet C Semin Med Genet. 2019 Mar;181(1):28-35. doi: 10.1002/ajmg.c.31672. Epub 2019 Feb 19.

PMID:
30779428
45.

Assessing the safety and outcomes of repeat transanal endoscopic microsurgery.

Ramkumar J, Letarte F, Karimuddin AA, Phang PT, Raval MJ, Brown CJ.

Surg Endosc. 2019 Jun;33(6):1976-1980. doi: 10.1007/s00464-018-6501-9. Epub 2019 Feb 11.

PMID:
30746573
46.

Functional changes in reef systems in warmer seas: Asymmetrical effects of altered grazing by a widespread crustacean mesograzer.

Pearson RM, Jinks KI, Brown CJ, Schlacher TA, Connolly RM.

Sci Total Environ. 2018 Dec 10;644:976-981. doi: 10.1016/j.scitotenv.2018.07.051. Epub 2018 Jul 11.

PMID:
30743894
47.

An improved method of obtaining electrocochleography recordings from Nucleus Hybrid cochlear implant users.

Tejani VD, Abbas PJ, Brown CJ, Woo J.

Hear Res. 2019 Mar 1;373:113-120. doi: 10.1016/j.heares.2019.01.002. Epub 2019 Jan 9.

PMID:
30665078
48.

Decline of coastal apex shark populations over the past half century.

Roff G, Brown CJ, Priest MA, Mumby PJ.

Commun Biol. 2018 Dec 13;1:223. doi: 10.1038/s42003-018-0233-1. eCollection 2018.

49.

Determination of the Minimal Important Change in the Life-Space Assessment.

Kennedy RE, Almutairi M, Williams CP, Sawyer P, Allman RM, Brown CJ.

J Am Geriatr Soc. 2019 Mar;67(3):565-569. doi: 10.1111/jgs.15707. Epub 2018 Dec 7.

PMID:
30536982
50.

Association Between Executive Dysfunction and Instrumental Activities of Daily Living: Racial and Ethnic Differences Among Community-Dwelling Older Adults in the Southeastern US.

Garrett SL, Kennedy RE, Sawyer P, Williams CP, Brown CJ, Allman RM.

J Natl Med Assoc. 2019 Jun;111(3):320-327. doi: 10.1016/j.jnma.2018.11.002. Epub 2018 Dec 4.

PMID:
30527966

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