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Ipsilesional Motor Cortex Plasticity Participates in Spontaneous Hindlimb Recovery after Lateral Hemisection of the Thoracic Spinal Cord in the Rat.

Brown AR, Martinez M.

J Neurosci. 2018 Nov 14;38(46):9977-9988. doi: 10.1523/JNEUROSCI.1062-18.2018. Epub 2018 Oct 9.


Remote biochemical verification of tobacco use: Reducing costs and improving methodological rigor with mailed oral cotinine swabs.

Moore MR, Mason MJ, Brown AR, Garcia CM, Seibers AD, Stephens CJ.

Addict Behav. 2018 Dec;87:151-154. doi: 10.1016/j.addbeh.2018.07.004. Epub 2018 Jul 6.


Adductor Canal Block Compared with Periarticular Bupivacaine Injection for Total Knee Arthroplasty: A Prospective Randomized Trial.

Grosso MJ, Murtaugh T, Lakra A, Brown AR, Maniker RB, Cooper HJ, Macaulay W, Shah RP, Geller JA.

J Bone Joint Surg Am. 2018 Jul 5;100(13):1141-1146. doi: 10.2106/JBJS.17.01177.


A Novel Adaptation Mechanism Underpinning Algal Colonization of a Nuclear Fuel Storage Pond.

MeGraw VE, Brown AR, Boothman C, Goodacre R, Morris K, Sigee D, Anderson L, Lloyd JR.

MBio. 2018 Jun 26;9(3). pii: e02395-17. doi: 10.1128/mBio.02395-17.


Multiple communication mechanisms between sensor kinases are crucial for virulence in Pseudomonas aeruginosa.

Francis VI, Waters EM, Finton-James SE, Gori A, Kadioglu A, Brown AR, Porter SL.

Nat Commun. 2018 Jun 7;9(1):2219. doi: 10.1038/s41467-018-04640-8.


Choisir avec soin : les 10 principales recommandations de la SOGC.

Green CR, Blake JM, Carson GD, Po L, Brown ARH, Friedman CL.

J Obstet Gynaecol Can. 2018 Jun;40(6):e443-e450. doi: 10.1016/j.jogc.2018.04.023. French. No abstract available.


Choosing Wisely: SOGC's Top 10 Recommendations.

Green CR, Blake JM, Carson GD, Po L, Brown ARH, Friedman CL.

J Obstet Gynaecol Can. 2018 Jun;40(6):716-722. doi: 10.1016/j.jogc.2018.04.024. No abstract available.


A Tablet-Based Educational Tool: Toward More Comprehensive Pediatric Patient Education.

Clifton DC, Benjamin RW, Brown AR, Ostrovsky DA, Narayan AP.

Clin Pediatr (Phila). 2018 Sep;57(10):1176-1182. doi: 10.1177/0009922818766621. Epub 2018 Mar 24.


Early life exposure to ethinylestradiol enhances subsequent responses to environmental estrogens measured in a novel transgenic zebrafish.

Green JM, Lange A, Scott A, Trznadel M, Wai HA, Takesono A, Brown AR, Owen SF, Kudoh T, Tyler CR.

Sci Rep. 2018 Feb 9;8(1):2699. doi: 10.1038/s41598-018-20922-z.


Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF-06372865.

Nickolls SA, Gurrell R, van Amerongen G, Kammonen J, Cao L, Brown AR, Stead C, Mead A, Watson C, Hsu C, Owen RM, Pike A, Fish RL, Chen L, Qiu R, Morris ED, Feng G, Whitlock M, Gorman D, van Gerven J, Reynolds DS, Dua P, Butt RP.

Br J Pharmacol. 2018 Feb;175(4):708-725. doi: 10.1111/bph.14119. Epub 2018 Jan 18.


Decreased risk of knee buckling with adductor canal block versus femoral nerve block in total knee arthroplasty: a retrospective cohort study.

Thacher RR, Hickernell TR, Grosso MJ, Shah R, Cooper HJ, Maniker R, Brown AR, Geller J.

Arthroplast Today. 2017 Apr 15;3(4):281-285. doi: 10.1016/j.artd.2017.02.008. eCollection 2017 Dec.


Three-Hour Bundle Compliance and Outcomes in Patients With Undiagnosed Severe Sepsis.

Deis AS, Whiles BB, Brown AR, Satterwhite CL, Simpson SQ.

Chest. 2018 Jan;153(1):39-45. doi: 10.1016/j.chest.2017.09.031. Epub 2017 Oct 5.


Helium Nanodroplet Isolation of the Cyclobutyl, 1-Methylallyl, and Allylcarbinyl Radicals: Infrared Spectroscopy and Ab Initio Computations.

Brown AR, Franke PR, Douberly GE.

J Phys Chem A. 2017 Oct 12;121(40):7576-7587. doi: 10.1021/acs.jpca.7b07852. Epub 2017 Oct 4.


Capturing ecology in modeling approaches applied to environmental risk assessment of endocrine active chemicals in fish.

Mintram KS, Brown AR, Maynard SK, Thorbek P, Tyler CR.

Crit Rev Toxicol. 2018 Feb;48(2):109-120. doi: 10.1080/10408444.2017.1367756. Epub 2017 Sep 20.


Motivational wheel running reverses cueing behavioural inflexibility in rodents.

Chomiak T, Brown AR, Teskey GC, Hu B.

J Neural Transm (Vienna). 2017 Dec;124(12):1635-1640. doi: 10.1007/s00702-017-1790-z. Epub 2017 Sep 18.


Endogenous neurosteroids influence synaptic GABAA receptors during postnatal development.

Belelli D, Brown AR, Mitchell SJ, Gunn BG, Herd MB, Phillips GD, Seifi M, Swinny JD, Lambert JJ.

J Neuroendocrinol. 2018 Feb;30(2). doi: 10.1111/jne.12537. Review.


Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort.

Mitchelmore PJ, Randall J, Bull MJ, Moore KA, O'Neill PA, Paszkiewicz K, Mahenthiralingam E, Scotton CJ, Sheldon CD, Withers NJ, Brown AR.

Thorax. 2017 Aug 26. pii: thoraxjnl-2016-209889. doi: 10.1136/thoraxjnl-2016-209889. [Epub ahead of print]


Selective inhibition of extra-synaptic α5-GABAA receptors by S44819, a new therapeutic agent.

Etherington LA, Mihalik B, Pálvölgyi A, Ling I, Pallagi K, Kertész S, Varga P, Gunn BG, Brown AR, Livesey MR, Monteiro O, Belelli D, Barkóczy J, Spedding M, Gacsályi I, Antoni FA, Lambert JJ.

Neuropharmacology. 2017 Oct;125:353-364. doi: 10.1016/j.neuropharm.2017.08.012. Epub 2017 Aug 12.


Secondary Metabolites from the Leaves of the Medicinal Plant Goldenseal (Hydrastis canadensis).

Leyte-Lugo M, Britton ER, Foil DH, Brown AR, Todd DA, Rivera-Chávez J, Oberlies NH, Cech NB.

Phytochem Lett. 2017 Jun;20:54-60. doi: 10.1016/j.phytol.2017.03.012. Epub 2017 Apr 15.


Bioavailability and Kidney Responses to Diclofenac in the Fathead Minnow (Pimephales promelas).

Bickley LK, van Aerle R, Brown AR, Hargreaves A, Huby R, Cammack V, Jackson R, Santos EM, Tyler CR.

Environ Sci Technol. 2017 Feb 7;51(3):1764-1774. doi: 10.1021/acs.est.6b05079. Epub 2017 Jan 26.


Is an ecosystem services-based approach developed for setting specific protection goals for plant protection products applicable to other chemicals?

Maltby L, Jackson M, Whale G, Brown AR, Hamer M, Solga A, Kabouw P, Woods R, Marshall S.

Sci Total Environ. 2017 Feb 15;580:1222-1236. doi: 10.1016/j.scitotenv.2016.12.083. Epub 2016 Dec 24.


Verbal Communication During Airway Management and Emergent Endotracheal Intubation: Observations of Team Behavior Among Multi-institutional Pediatric Intensive Care Unit In Situ Simulations.

Rozenfeld RA, Nannicelli AP, Brown AR, Eppich WJ, Woods DM, Lestrud SO, Noah ZL, Holl JL.

J Patient Saf. 2016 Nov 2. [Epub ahead of print]


Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei.

McLean CJ, Marles-Wright J, Custodio R, Lowther J, Kennedy AJ, Pollock J, Clarke DJ, Brown AR, Campopiano DJ.

J Lipid Res. 2017 Jan;58(1):137-150. doi: 10.1194/jlr.M071258. Epub 2016 Oct 26.


Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei.

Custódio R, McLean CJ, Scott AE, Lowther J, Kennedy A, Clarke DJ, Campopiano DJ, Sarkar-Tyson M, Brown AR.

Mol Microbiol. 2016 Dec;102(6):1004-1019. doi: 10.1111/mmi.13531. Epub 2016 Sep 26.


A Bayesian comparative effectiveness trial in action: developing a platform for multisite study adaptive randomization.

Brown AR, Gajewski BJ, Aaronson LS, Mudaranthakam DP, Hunt SL, Berry SM, Quintana M, Pasnoor M, Dimachkie MM, Jawdat O, Herbelin L, Barohn RJ.

Trials. 2016 Aug 31;17(1):428. doi: 10.1186/s13063-016-1544-5.


Crosstalk between mismatch repair and base excision repair in human gastric cancer.

Simonelli V, Leuzzi G, Basile G, D'Errico M, Fortini P, Franchitto A, Viti V, Brown AR, Parlanti E, Pascucci B, Palli D, Giuliani A, Palombo F, Sobol RW, Dogliotti E.

Oncotarget. 2016 Jun 20;8(49):84827-84840. doi: 10.18632/oncotarget.10185. eCollection 2017 Oct 17.


Toward the definition of specific protection goals for the environmental risk assessment of chemicals: A perspective on environmental regulation in Europe.

Brown AR, Whale G, Jackson M, Marshall S, Hamer M, Solga A, Kabouw P, Galay-Burgos M, Woods R, Nadzialek S, Maltby L.

Integr Environ Assess Manag. 2017 Jan;13(1):17-37. doi: 10.1002/ieam.1797. Epub 2016 Aug 10. Review.


Holographic Complexity Equals Bulk Action?

Brown AR, Roberts DA, Susskind L, Swingle B, Zhao Y.

Phys Rev Lett. 2016 May 13;116(19):191301. doi: 10.1103/PhysRevLett.116.191301. Epub 2016 May 9.


High-Content and Semi-Automated Quantification of Responses to Estrogenic Chemicals Using a Novel Translucent Transgenic Zebrafish.

Green JM, Metz J, Lee O, Trznadel M, Takesono A, Brown AR, Owen SF, Kudoh T, Tyler CR.

Environ Sci Technol. 2016 Jun 21;50(12):6536-45. doi: 10.1021/acs.est.6b01243. Epub 2016 Jun 7.


Development and testing of a new system for assessing wheel-running behaviour in rodents.

Chomiak T, Block EW, Brown AR, Teskey GC, Hu B.

BMC Res Notes. 2016 May 5;9:262. doi: 10.1186/s13104-016-2059-6.


Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.

Cao L, McDonnell A, Nitzsche A, Alexandrou A, Saintot PP, Loucif AJ, Brown AR, Young G, Mis M, Randall A, Waxman SG, Stanley P, Kirby S, Tarabar S, Gutteridge A, Butt R, McKernan RM, Whiting P, Ali Z, Bilsland J, Stevens EB.

Sci Transl Med. 2016 Apr 20;8(335):335ra56. doi: 10.1126/scitranslmed.aad7653.


Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release.

Alexandrou AJ, Brown AR, Chapman ML, Estacion M, Turner J, Mis MA, Wilbrey A, Payne EC, Gutteridge A, Cox PJ, Doyle R, Printzenhoff D, Lin Z, Marron BE, West C, Swain NA, Storer RI, Stupple PA, Castle NA, Hounshell JA, Rivara M, Randall A, Dib-Hajj SD, Krafte D, Waxman SG, Patel MK, Butt RP, Stevens EB.

PLoS One. 2016 Apr 6;11(4):e0152405. doi: 10.1371/journal.pone.0152405. eCollection 2016.


During postnatal development endogenous neurosteroids influence GABA-ergic neurotransmission of mouse cortical neurons.

Brown AR, Mitchell SJ, Peden DR, Herd MB, Seifi M, Swinny JD, Belelli D, Lambert JJ.

Neuropharmacology. 2016 Apr;103:163-73. doi: 10.1016/j.neuropharm.2015.11.019. Epub 2015 Dec 2.


Repurposed biological scaffolds: kidney to pancreas.

Willenberg BJ, Oca-Cossio J, Cai Y, Brown AR, Clapp WL, Abrahamson DR, Terada N, Ellison GW, Mathews CE, Batich CD, Ross EA.

Organogenesis. 2015;11(2):47-57. doi: 10.1080/15476278.2015.1067354.


Krüppel-like factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling.

Brown AR, Simmen RC, Raj VR, Van TT, MacLeod SL, Simmen FA.

Carcinogenesis. 2015 Sep;36(9):946-55. doi: 10.1093/carcin/bgv104. Epub 2015 Jul 25.


Failure mode and effects analysis: a comparison of two common risk prioritisation methods.

McElroy LM, Khorzad R, Nannicelli AP, Brown AR, Ladner DP, Holl JL.

BMJ Qual Saf. 2016 May;25(5):329-36. doi: 10.1136/bmjqs-2015-004130. Epub 2015 Jul 13.


Phenotypic Characterisation of Shewanella oneidensis MR-1 Exposed to X-Radiation.

Brown AR, Correa E, Xu Y, AlMasoud N, Pimblott SM, Goodacre R, Lloyd JR.

PLoS One. 2015 Jun 22;10(6):e0131249. doi: 10.1371/journal.pone.0131249. eCollection 2015.


A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition.

Brown AR, Ettefagh KA, Todd D, Cole PS, Egan JM, Foil DH, Graf TN, Schindler BD, Kaatz GW, Cech NB.

PLoS One. 2015 May 11;10(5):e0124814. doi: 10.1371/journal.pone.0124814. eCollection 2015.


Intracortical Microstimulation (ICMS) Activates Motor Cortex Layer 5 Pyramidal Neurons Mainly Transsynaptically.

Hussin AT, Boychuk JA, Brown AR, Pittman QJ, Teskey GC.

Brain Stimul. 2015 Jul-Aug;8(4):742-50. doi: 10.1016/j.brs.2015.03.003. Epub 2015 Mar 27.


The impact of gamma radiation on sediment microbial processes.

Brown AR, Boothman C, Pimblott SM, Lloyd JR.

Appl Environ Microbiol. 2015 Jun 15;81(12):4014-25. doi: 10.1128/AEM.00590-15. Epub 2015 Apr 3.


Climate change and pollution speed declines in zebrafish populations.

Brown AR, Owen SF, Peters J, Zhang Y, Soffker M, Paull GC, Hosken DJ, Wahab MA, Tyler CR.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1237-46. doi: 10.1073/pnas.1416269112. Epub 2015 Mar 2.


A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability.

Payne CE, Brown AR, Theile JW, Loucif AJ, Alexandrou AJ, Fuller MD, Mahoney JH, Antonio BM, Gerlach AC, Printzenhoff DM, Prime RL, Stockbridge G, Kirkup AJ, Bannon AW, England S, Chapman ML, Bagal S, Roeloffs R, Anand U, Anand P, Bungay PJ, Kemp M, Butt RP, Stevens EB.

Br J Pharmacol. 2015 May;172(10):2654-70. doi: 10.1111/bph.13092. Epub 2015 Apr 10.


Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones.

Brown AR, Herd MB, Belelli D, Lambert JJ.

J Physiol. 2015 Jan 1;593(1):267-84. doi: 10.1113/jphysiol.2014.280263. Epub 2014 Dec 3.


HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β.

Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, Yates NA, Lan L, Vens C, Sobol RW.

Nat Commun. 2014 Nov 26;5:5513. doi: 10.1038/ncomms6513.


Assessing variation in the potential susceptibility of fish to pharmaceuticals, considering evolutionary differences in their physiology and ecology.

Brown AR, Gunnarsson L, Kristiansson E, Tyler CR.

Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). pii: 20130576. doi: 10.1098/rstb.2013.0576.


Medicating the environment: assessing risks of pharmaceuticals to wildlife and ecosystems.

Arnold KE, Brown AR, Ankley GT, Sumpter JP.

Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). pii: 20130569. doi: 10.1098/rstb.2013.0569.


Enhanced gastrointestinal expression of cytosolic malic enzyme (ME1) induces intestinal and liver lipogenic gene expression and intestinal cell proliferation in mice.

Al-Dwairi A, Brown AR, Pabona JM, Van TH, Hamdan H, Mercado CP, Quick CM, Wight PA, Simmen RC, Simmen FA.

PLoS One. 2014 Nov 17;9(11):e113058. doi: 10.1371/journal.pone.0113058. eCollection 2014.


Motor cortex is functionally organized as a set of spatially distinct representations for complex movements.

Brown AR, Teskey GC.

J Neurosci. 2014 Oct 8;34(41):13574-85. doi: 10.1523/JNEUROSCI.2500-14.2014.


Connective tissue growth factor and integrin αvβ6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice.

Pi L, Robinson PM, Jorgensen M, Oh SH, Brown AR, Weinreb PH, Trinh TL, Yianni P, Liu C, Leask A, Violette SM, Scott EW, Schultz GS, Petersen BE.

Hepatology. 2015 Feb;61(2):678-91. doi: 10.1002/hep.27425.

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