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Items: 1 to 50 of 560

1.

RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.

Brown AL, Arts P, Carmichael CL, Babic M, Dobbins J, Chong CE, Schreiber AW, Feng J, Phillips K, Wang PPS, Ha T, Homan CC, King-Smith SL, Rawlings L, Vakulin C, Dubowsky A, Burdett J, Moore S, McKavanagh G, Henry D, Wells A, Mercorella B, Nicola M, Suttle J, Wilkins E, Li XC, Michaud J, Brautigan P, Cannon P, Altree M, Jaensch L, Fine M, Butcher C, D'Andrea RJ, Lewis ID, Hiwase DK, Papaemmanuil E, Horwitz MS, Natsoulis G, Rienhoff HY, Patton N, Mapp S, Susman R, Morgan S, Cooney J, Currie M, Popat U, Bochtler T, Izraeli S, Bradstock K, Godley LA, Krämer A, Fröhling S, Wei AH, Forsyth C, Mar Fan H, Poplawski NK, Hahn CN, Scott HS.

Blood Adv. 2020 Mar 24;4(6):1131-1144. doi: 10.1182/bloodadvances.2019000901.

2.

Utilization of archived neonatal dried blood spots for genome-wide genotyping.

Sok P, Lupo PJ, Richard MA, Rabin KR, Ehli EA, Kallsen NA, Davies GE, Scheurer ME, Brown AL.

PLoS One. 2020 Feb 21;15(2):e0229352. doi: 10.1371/journal.pone.0229352. eCollection 2020.

3.

Two monogenic disorders masquerading as one: severe congenital neutropenia with monocytosis and non-syndromic sensorineural hearing loss.

Venugopal P, Gagliardi L, Forsyth C, Feng J, Phillips K, Babic M, Poplawski NK, Rienhoff HY Jr, Schreiber AW, Hahn CN, Brown AL, Scott HS.

BMC Med Genet. 2020 Feb 17;21(1):35. doi: 10.1186/s12881-020-0971-z.

4.

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.

Kim J, Gupta R, Blanco LP, Yang S, Shteinfer-Kuzmine A, Wang K, Zhu J, Yoon HE, Wang X, Kerkhofs M, Kang H, Brown AL, Park SJ, Xu X, Zandee van Rilland E, Kim MK, Cohen JI, Kaplan MJ, Shoshan-Barmatz V, Chung JH.

Science. 2019 Dec 20;366(6472):1531-1536. doi: 10.1126/science.aav4011. Epub 2019 Dec 19.

PMID:
31857488
5.

Dietary Choline Supplementation Attenuates High-Fat-Diet-Induced Hepatocellular Carcinoma in Mice.

Brown AL, Conrad K, Allende DS, Gromovsky AD, Zhang R, Neumann CK, Owens AP, Tranter M, Helsley RN.

J Nutr. 2019 Dec 18. pii: nxz315. doi: 10.1093/jn/nxz315. [Epub ahead of print]

PMID:
31851339
6.

APOBEC3A is a prominent cytidine deaminase in breast cancer.

Cortez LM, Brown AL, Dennis MA, Collins CD, Brown AJ, Mitchell D, Mertz TM, Roberts SA.

PLoS Genet. 2019 Dec 16;15(12):e1008545. doi: 10.1371/journal.pgen.1008545. eCollection 2019 Dec.

7.

Effect of sensorineural hearing loss on neurocognitive and adaptive functioning in survivors of pediatric embryonal brain tumor.

Heitzer AM, Villagran AM, Raghubar K, Brown AL, Camet ML, Ris MD, Hanning JH, Okcu MF, Paulino AC, Chintagumpala M, Kahalley LS.

J Neurooncol. 2020 Jan;146(1):147-156. doi: 10.1007/s11060-019-03356-z. Epub 2019 Nov 28.

PMID:
31782051
8.
9.

Interventions for pregnant women who use tobacco and other substances: a systematic review protocol.

Jackson MA, Baker AL, McCarter KL, Brown AL, Gould GS, Dunlop AJ.

BMJ Open. 2019 Nov 11;9(11):e032449. doi: 10.1136/bmjopen-2019-032449.

10.

β-Cell and renal transplantation options for diabetes.

Flatt AJS, Bennett D, Counter C, Brown AL, White SA, Shaw JAM.

Diabet Med. 2020 Apr;37(4):580-592. doi: 10.1111/dme.14177. Epub 2019 Dec 18. Review.

PMID:
31705689
11.

ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants.

Luo X, Feurstein S, Mohan S, Porter CC, Jackson SA, Keel S, Chicka M, Brown AL, Kesserwan C, Agarwal A, Luo M, Li Z, Ross JE, Baliakas P, Pineda-Alvarez D, DiNardo CD, Bertuch AA, Mehta N, Vulliamy T, Wang Y, Nichols KE, Malcovati L, Walsh MF, Rawlings LH, McWeeney SK, Soulier J, Raimbault A, Routbort MJ, Zhang L, Ryan G, Speck NA, Plon SE, Wu D, Godley LA.

Blood Adv. 2019 Oct 22;3(20):2962-2979. doi: 10.1182/bloodadvances.2019000644.

12.

Correct application of variant classification guidelines in germline RUNX1 mutated disorders to assist clinical diagnosis.

Brown AL, Hahn C, Hiwase D, Godley LA, Scott HS.

Leuk Lymphoma. 2020 Jan;61(1):246-247. doi: 10.1080/10428194.2019.1680842. Epub 2019 Oct 24. No abstract available.

PMID:
31647332
13.

Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors.

Merino J, Jablonski KA, Mercader JM, Kahn SE, Chen L, Harden M, Delahanty LM, Araneta MRG, Walford GA, Jacobs SBR, Ibebuogu UN, Franks PW, Knowler WC, Florez JC; Diabetes Prevention Program Research Group.

Diabetes. 2020 Jan;69(1):112-120. doi: 10.2337/db19-0097. Epub 2019 Oct 21.

PMID:
31636172
14.

Metabolomic profiling identifies pathways associated with minimal residual disease in childhood acute lymphoblastic leukaemia.

Schraw JM, Junco JJ, Brown AL, Scheurer ME, Rabin KR, Lupo PJ.

EBioMedicine. 2019 Oct;48:49-57. doi: 10.1016/j.ebiom.2019.09.033. Epub 2019 Oct 17.

15.

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.

Helsley RN, Varadharajan V, Brown AL, Gromovsky AD, Schugar RC, Ramachandiran I, Fung K, Kabbany MN, Banerjee R, Neumann CK, Finney C, Pathak P, Orabi D, Osborn LJ, Massey W, Zhang R, Kadam A, Sansbury BE, Pan C, Sacks J, Lee RG, Crooke RM, Graham MJ, Lemieux ME, Gogonea V, Kirwan JP, Allende DS, Civelek M, Fox PL, Rudel LL, Lusis AJ, Spite M, Brown JM.

Elife. 2019 Oct 17;8. pii: e49882. doi: 10.7554/eLife.49882.

16.

Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program.

Chen ZZ, Liu J, Morningstar J, Heckman-Stoddard BM, Lee CG, Dagogo-Jack S, Ferguson JF, Hamman RF, Knowler WC, Mather KJ, Perreault L, Florez JC, Wang TJ, Clish C, Temprosa M, Gerszten RE; Diabetes Prevention Program Research Group.

Diabetes. 2019 Dec;68(12):2337-2349. doi: 10.2337/db19-0236. Epub 2019 Oct 3.

PMID:
31582408
18.

Self-perception of aging among HIV-positive and HIV-negative participants in the Multicenter AIDS Cohort Study.

Nieves-Lugo K, Ware D, Friedman MR, Haberlen S, Egan J, Brown AL, Dakwar O, Plankey M.

AIDS Care. 2019 Sep 23:1-11. doi: 10.1080/09540121.2019.1668536. [Epub ahead of print]

PMID:
31547674
19.

Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome.

Brown AL, de Smith AJ, Gant VU, Yang W, Scheurer ME, Walsh KM, Chernus JM, Kallsen NA, Peyton SA, Davies GE, Ehli EA, Winick N, Heerema NA, Carroll AJ, Borowitz MJ, Wood BL, Carroll WL, Raetz EA, Feingold E, Devidas M, Barcellos LF, Hansen HM, Morimoto L, Kang AY, Smirnov I, Healy J, Laverdière C, Sinnett D, Taub JW, Birch JM, Thompson P, Spector LG, Pombo-de-Oliveira MS, DeWan AT, Mullighan CG, Hunger SP, Pui CH, Loh ML, Zwick ME, Metayer C, Ma X, Mueller BA, Sherman SL, Wiemels JL, Relling MV, Yang JJ, Lupo PJ, Rabin KR.

Blood. 2019 Oct 10;134(15):1227-1237. doi: 10.1182/blood.2018890764.

PMID:
31350265
20.

Dissemination and Implementation Program in Hypertension in Rwanda: Report on Initial Training and Evaluation.

Baumann AA, Mutabazi V, Brown AL, Hooley C, Reeds D, Ingabire C, Ndahindwa V, Nishimwe A, Cade WT, de Las Fuentes L, Proctor EK, Karengera S, Schecthman KB, Goss CW, Yarasheski K, Newsome B, Mutimura E, Davila-Roman VG.

Glob Heart. 2019 Jun;14(2):135-141. doi: 10.1016/j.gheart.2019.06.001.

21.

Survival disparities for second primary malignancies diagnosed among childhood cancer survivors: A population-based assessment.

Brown AL, Arroyo VM, Agrusa JE, Scheurer ME, Gramatges MM, Lupo PJ.

Cancer. 2019 Oct 15;125(20):3623-3630. doi: 10.1002/cncr.32356. Epub 2019 Jun 28.

PMID:
31251393
22.

Association Between Birth Defects and Cancer Risk Among Children and Adolescents in a Population-Based Assessment of 10 Million Live Births.

Lupo PJ, Schraw JM, Desrosiers TA, Nembhard WN, Langlois PH, Canfield MA, Copeland G, Meyer RE, Brown AL, Chambers TM, Sok P, Danysh HE, Carozza SE, Sisoudiya SD, Hilsenbeck SG, Janitz AE, Oster ME, Scheuerle AE, Schiffman JD, Luo C, Mian A, Mueller BA, Huff CD, Rasmussen SA, Scheurer ME, Plon SE.

JAMA Oncol. 2019 Jun 20. doi: 10.1001/jamaoncol.2019.1215. [Epub ahead of print] Erratum in: JAMA Oncol. 2019 Aug 1;5(8):1232.

PMID:
31219523
23.

Do Psychopathic Traits Statistically Protect Against PTSD? A Retrospective Study of Vietnam Veterans.

Bowes SM, Brown AL, Thompson WW, Sellbom M, Lilienfeld SO.

J Pers Disord. 2019 Jun 17:1-S4. doi: 10.1521/pedi_2019_33_432. [Epub ahead of print]

PMID:
31206341
24.

MiR-455-3p, miR-150 and miR-375 are aberrantly expressed in salivary gland adenoid cystic carcinoma and polymorphous adenocarcinoma.

Brown AL, Al-Samadi A, Sperandio M, Soares AB, Teixeira LN, Martinez EF, Demasi APD, Araújo VC, Leivo I, Salo T, Passador-Santos F.

J Oral Pathol Med. 2019 Oct;48(9):840-845. doi: 10.1111/jop.12894. Epub 2019 Jun 25.

PMID:
31165496
25.

Weight trends in a multiethnic cohort of pediatric acute lymphoblastic leukemia survivors: A longitudinal analysis.

Foster KL, Kern KD, Chambers TM, Lupo PJ, Kamdar KY, Scheurer ME, Brown AL.

PLoS One. 2019 May 31;14(5):e0217932. doi: 10.1371/journal.pone.0217932. eCollection 2019.

26.

Adaptive functioning in pediatric brain tumor survivors: An examination of ethnicity and socioeconomic status.

Raghubar KP, Orobio J, Ris MD, Heitzer AM, Roth A, Brown AL, Okcu MF, Chintagumpala M, Grosshans DR, Paulino AC, Mahajan A, Kahalley LS.

Pediatr Blood Cancer. 2019 Sep;66(9):e27800. doi: 10.1002/pbc.27800. Epub 2019 May 27.

PMID:
31134755
27.

The role of genetic variation in DGKK on moderate and severe hypospadias.

Richard MA, Sok P, Canon S, Brown AL, Peckham-Gregory EC, Nembhard WN, Carmichael SL, Ehli EA, Kallsen NA, Peyton SA, Davies GE, Patel A, Zamilpa I, Wyatt RA, Hobbs CA, Scheurer ME, Lupo PJ.

Birth Defects Res. 2019 Aug 1;111(13):932-937. doi: 10.1002/bdr2.1522. Epub 2019 May 18.

PMID:
31102501
28.

The mutational burden of therapy-related myeloid neoplasms is similar to primary myelodysplastic syndrome but has a distinctive distribution.

Singhal D, Wee LYA, Kutyna MM, Chhetri R, Geoghegan J, Schreiber AW, Feng J, Wang PP, Babic M, Parker WT, Hiwase S, Edwards S, Moore S, Branford S, Kuzmanovic T, Singhal N, Gowda R, Brown AL, Arts P, To LB, Bardy PG, Lewis ID, D'Andrea RJ, Maciejewski JP, Scott HS, Hahn CN, Hiwase DK.

Leukemia. 2019 Dec;33(12):2842-2853. doi: 10.1038/s41375-019-0479-8. Epub 2019 May 14.

PMID:
31089247
29.

Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Brown AL, Li M, Goncearenco A, Panchenko AR.

PLoS Comput Biol. 2019 Apr 29;15(4):e1006981. doi: 10.1371/journal.pcbi.1006981. eCollection 2019 Apr.

30.

Genomic subtyping and therapeutic targeting of acute erythroleukemia.

Iacobucci I, Wen J, Meggendorfer M, Choi JK, Shi L, Pounds SB, Carmichael CL, Masih KE, Morris SM, Lindsley RC, Janke LJ, Alexander TB, Song G, Qu C, Li Y, Payne-Turner D, Tomizawa D, Kiyokawa N, Valentine M, Valentine V, Basso G, Locatelli F, Enemark EJ, Kham SKY, Yeoh AEJ, Ma X, Zhou X, Sioson E, Rusch M, Ries RE, Stieglitz E, Hunger SP, Wei AH, To LB, Lewis ID, D'Andrea RJ, Kile BT, Brown AL, Scott HS, Hahn CN, Marlton P, Pei D, Cheng C, Loh ML, Ebert BL, Meshinchi S, Haferlach T, Mullighan CG.

Nat Genet. 2019 Apr;51(4):694-704. doi: 10.1038/s41588-019-0375-1. Epub 2019 Mar 29.

31.

Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis.

Ratmann O, Grabowski MK, Hall M, Golubchik T, Wymant C, Abeler-Dörner L, Bonsall D, Hoppe A, Brown AL, de Oliveira T, Gall A, Kellam P, Pillay D, Kagaayi J, Kigozi G, Quinn TC, Wawer MJ, Laeyendecker O, Serwadda D, Gray RH, Fraser C; PANGEA Consortium and Rakai Health Sciences Program.

Nat Commun. 2019 Mar 29;10(1):1411. doi: 10.1038/s41467-019-09139-4.

32.

A novel germline SAMD9L mutation in a family with ataxia-pancytopenia syndrome and pediatric acute lymphoblastic leukemia.

Cheah JJC, Brown AL, Schreiber AW, Feng J, Babic M, Moore S, Young CC, Fine M, Phillips K, Guandalini M, Wilson P, Poplawski N, Hahn CN, Scott HS.

Haematologica. 2019 Jul;104(7):e318-e321. doi: 10.3324/haematol.2018.207316. Epub 2019 Mar 28. No abstract available.

34.

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors.

Roper N, Gao S, Maity TK, Banday AR, Zhang X, Venugopalan A, Cultraro CM, Patidar R, Sindiri S, Brown AL, Goncearenco A, Panchenko AR, Biswas R, Thomas A, Rajan A, Carter CA, Kleiner DE, Hewitt SM, Khan J, Prokunina-Olsson L, Guha U.

Cell Rep. 2019 Mar 5;26(10):2651-2666.e6. doi: 10.1016/j.celrep.2019.02.028.

35.

Breast MRI ordering practices in a large health care network.

Brown AL, Phillips J, Mehta TS, Brook A, Sharpe RE Jr, Slanetz PJ, Dialani V.

Breast J. 2019 Mar;25(2):262-268. doi: 10.1111/tbj.13198. Epub 2019 Feb 12.

PMID:
30746809
36.

Pilot study of DNA methylation-derived neutrophil-to-lymphocyte ratio and survival in pediatric medulloblastoma.

Arroyo VM, Lupo PJ, Scheurer ME, Rednam SP, Murray J, Okcu MF, Chintagumpala MM, Brown AL.

Cancer Epidemiol. 2019 Apr;59:71-74. doi: 10.1016/j.canep.2019.01.011. Epub 2019 Jan 29.

37.

Nanoalginates via Inverse-Micelle Synthesis: Doxorubicin-Encapsulation and Breast Cancer Cytotoxicity.

Rosch JG, Brown AL, DuRoss AN, DuRoss EL, Sahay G, Sun C.

Nanoscale Res Lett. 2018 Nov 3;13(1):350. doi: 10.1186/s11671-018-2748-2.

38.

DNA methylation and obesity in survivors of pediatric acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study.

Lupo PJ, Brown AL, Arroyo VM, Kamdar KY, Belmont JW, Scheurer ME, Leisenring WM, Gramatges MM, Okcu MF, Yasui Y, Oeffinger KC, Robison LL, Armstrong GT, Bhatia S.

Genes Chromosomes Cancer. 2019 Jan;58(1):52-59. doi: 10.1002/gcc.22701. Epub 2018 Dec 4.

39.

Vaccine confidence and hesitancy in Brazil.

Brown AL, Sperandio M, Turssi CP, Leite RMA, Berton VF, Succi RM, Larson H, Napimoga MH.

Cad Saude Publica. 2018 Sep 21;34(9):e00011618. doi: 10.1590/0102-311X00011618.

40.

Disparities in Neurotoxicity Risk and Outcomes among Pediatric Acute Lymphoblastic Leukemia Patients.

Taylor OA, Brown AL, Brackett J, Dreyer ZE, Moore IK, Mitby P, Hooke MC, Hockenberry MJ, Lupo PJ, Scheurer ME.

Clin Cancer Res. 2018 Oct 15;24(20):5012-5017. doi: 10.1158/1078-0432.CCR-18-0939. Epub 2018 Sep 11.

41.

A Review on Energy, Environmental, and Sustainability Implications of Connected and Automated Vehicles.

Taiebat M, Brown AL, Safford HR, Qu S, Xu M.

Environ Sci Technol. 2018 Oct 16;52(20):11449-11465. doi: 10.1021/acs.est.8b00127. Epub 2018 Sep 26. Review.

42.

For Better or for Worse? A Systematic Review of the Evidence on Social Media Use and Depression Among Lesbian, Gay, and Bisexual Minorities.

Escobar-Viera CG, Whitfield DL, Wessel CB, Shensa A, Sidani JE, Brown AL, Chandler CJ, Hoffman BL, Marshal MP, Primack BA.

JMIR Ment Health. 2018 Jul 23;5(3):e10496. doi: 10.2196/10496. Review.

43.

Facile Synthesis of Ligand-Free Iridium Nanoparticles and Their In Vitro Biocompatibility.

Brown AL, Winter H, Goforth AM, Sahay G, Sun C.

Nanoscale Res Lett. 2018 Jul 13;13(1):208. doi: 10.1186/s11671-018-2621-3.

44.

The role of self-objectification and women's blame, sympathy, and support for a rape victim.

Bevens CL, Brown AL, Loughnan S.

PLoS One. 2018 Jun 28;13(6):e0199808. doi: 10.1371/journal.pone.0199808. eCollection 2018.

45.

Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia.

Maung KZY, Leo PJ, Bassal M, Casolari DA, Gray JX, Bray SC, Pederson S, Singhal D, Samaraweera SE, Nguyen T, Cildir G, Marshall M, Ewing A, Duncan EL, Brown MA, Saal R, Tergaonkar V, To LB, Marlton P, Gill D, Lewis I, Deans AJ, Brown AL, D'Andrea RJ, Gonda TJ.

Blood Cancer J. 2018 Jun 1;8(6):50. doi: 10.1038/s41408-018-0090-7. No abstract available.

46.

Biodistribution and Toxicity of Micellar Platinum Nanoparticles in Mice via Intravenous Administration.

Brown AL, Kai MP, DuRoss AN, Sahay G, Sun C.

Nanomaterials (Basel). 2018 Jun 7;8(6). pii: E410. doi: 10.3390/nano8060410.

47.

Mechanistic target of rapamycin: integrating growth factor and nutrient signaling in the collecting duct.

Brown AL, Fluitt MB, Ecelbarger CM.

Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F413-F416. doi: 10.1152/ajprenal.00170.2018. Epub 2018 May 30. Review.

48.

The Effects of Exposure to Negative Social Reactions and Participant Gender on Attitudes and Behavior Toward a Rape Victim.

Brown AL.

Violence Against Women. 2019 Feb;25(2):208-222. doi: 10.1177/1077801218761603. Epub 2018 Mar 4.

PMID:
29504472
49.

Vermetid gastropods modify physical and chemical conditions above coral-algal interactions.

Brown AL, Osenberg CW.

Oecologia. 2018 Apr;186(4):1091-1099. doi: 10.1007/s00442-018-4091-9. Epub 2018 Feb 20.

PMID:
29464323
50.

Blocking incidental frustration during bargaining.

Vargas MES, Brown AL, Durkee CM, Sim H.

Cogn Emot. 2019 Mar;33(2):146-156. doi: 10.1080/02699931.2018.1436043. Epub 2018 Feb 8.

PMID:
29419354

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