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Items: 1 to 50 of 899

1.

Consulting prostate cancer cohort data uncovers transcriptional control: Regulation of the MARCH6 gene.

Coates HW, Chua NK, Brown AJ.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Aug 15. pii: S1388-1981(19)30148-9. doi: 10.1016/j.bbalip.2019.08.006. [Epub ahead of print]

PMID:
31422115
2.

Discordance of intracoronary pressure-based indices in severe angiographic stenosis: are we missing the flow?

Michail M, Ihdayhid AR, Brown AJ, Ko B.

Cardiovasc Interv Ther. 2019 Aug 6. doi: 10.1007/s12928-019-00609-6. [Epub ahead of print] No abstract available.

PMID:
31388970
3.

The Most Valuable Resource Is Time: Insights from a Novel National Program to Improve Retention of Physician-Scientists with Caregiving Responsibilities.

Jones RD, Miller J, Vitous CA, Krenz C, Brady KT, Brown AJ, Daumit GL, Drake AF, Fraser VJ, Hartmann KE, Hochman JS, Girdler S, Libby AM, Mangurian C, Regensteiner JG, Yonkers K, Jagsi R.

Acad Med. 2019 Jul 23. doi: 10.1097/ACM.0000000000002903. [Epub ahead of print]

PMID:
31348060
4.

Comparative efficacy of gypsy moth (Lepidoptera: Erebidae) entomopathogens on transgenic blight-tolerant and wild-type American, Chinese, and hybrid chestnuts (Fagales: Fagaceae).

Brown AJ, Newhouse AE, Powell WA, Parry D.

Insect Sci. 2019 Jul 24. doi: 10.1111/1744-7917.12713. [Epub ahead of print]

PMID:
31339228
5.

Heterogeneity of Plaque Structural Stress Is Increased in Plaques Leading to MACE: Insights From the PROSPECT Study.

Costopoulos C, Maehara A, Huang Y, Brown AJ, Gillard JH, Teng Z, Stone GW, Bennett MR.

JACC Cardiovasc Imaging. 2019 Jul 11. pii: S1936-878X(19)30559-5. doi: 10.1016/j.jcmg.2019.05.024. [Epub ahead of print]

6.

Prehospital Diagnosis and Management of Acute Myocardial Infarction.

Brown AJ, Ha FJ, Michail M, West NEJ.

In: Watson TJ, Ong PJL, Tcheng JE, editors. Primary Angioplasty: A Practical Guide [Internet]. Singapore: Springer; 2018. Chapter 2.
2018 Jul 14.

7.

Physiologically Relevant Alternative Carbon Sources Modulate Biofilm Formation, Cell Wall Architecture, and the Stress and Antifungal Resistance of Candida glabrata.

Chew SY, Ho KL, Cheah YK, Sandai D, Brown AJP, Than LTL.

Int J Mol Sci. 2019 Jun 28;20(13). pii: E3172. doi: 10.3390/ijms20133172.

8.

Peripheral Circadian Oscillators.

Brown AJ, Pendergast JS, Yamazaki S.

Yale J Biol Med. 2019 Jun 27;92(2):327-335. eCollection 2019 Jun. Review.

9.

Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase.

Brown AJ, Won JJ, Graham RL, Dinnon KH 3rd, Sims AC, Feng JY, Cihlar T, Denison MR, Baric RS, Sheahan TP.

Antiviral Res. 2019 Sep;169:104541. doi: 10.1016/j.antiviral.2019.104541. Epub 2019 Jun 21.

PMID:
31233808
10.

Raw genome sequence data for 13 isogenic Aspergillus fumigatus strains isolated over a 2 year period from a patient with chronic granulomatous disease.

Ballard E, Zoll J, Melchers WJG, Brown AJP, Warris A, Verweij PE.

Data Brief. 2019 May 23;25:104021. doi: 10.1016/j.dib.2019.104021. eCollection 2019 Aug.

11.

DNA damage and repair in patients with coronary artery disease: Correlation with plaque morphology using optical coherence tomography (DECODE study).

Shah N, Meira LB, Elliott RM, Hoole SP, West NE, Brown AJ, Bennett MR, Garcia-Garcia HM, Kuku KO, Dan K, Kolm P, Mariathas M, Curzen N, Mahmoudi M.

Cardiovasc Revasc Med. 2019 May 23. pii: S1553-8389(19)30294-5. doi: 10.1016/j.carrev.2019.04.028. [Epub ahead of print]

PMID:
31178349
12.

The Adaptor Protein Alix is Involved in the Interaction Between the Ubiquitin Ligase NEDD4-1 and its Targets, ABCG1 and ABCG4.

Alrosan A, Aleidi SM, Yang A, Brown AJ, Gelissen IC.

Int J Mol Sci. 2019 Jun 2;20(11). pii: E2714. doi: 10.3390/ijms20112714.

13.

Recreation of in-host acquired single nucleotide polymorphisms by CRISPR-Cas9 reveals an uncharacterised gene playing a role in Aspergillus fumigatus azole resistance via a non-cyp51A mediated resistance mechanism.

Ballard E, Weber J, Melchers WJG, Tammireddy S, Whitfield PD, Brakhage AA, Brown AJP, Verweij PE, Warris A.

Fungal Genet Biol. 2019 May 23;130:98-106. doi: 10.1016/j.fgb.2019.05.005. [Epub ahead of print]

14.

The FTO Gene and Measured Food Intake in 5- to 10-Year-Old Children Without Obesity.

Ranzenhofer LM, Mayer LES, Davis HA, Mielke-Maday HK, McInerney H, Korn R, Gupta N, Brown AJ, Schebendach J, Tanofsky-Kraff M, Thaker V, Chung WK, Leibel RL, Walsh BT, Rosenbaum M.

Obesity (Silver Spring). 2019 Jun;27(6):1023-1029. doi: 10.1002/oby.22464.

PMID:
31119882
15.

A very persistent chicken bone: two separate perforations from the same foreign object 2 months apart.

Brown AJ, Whitehead-Clarke T, Tudyka V.

BMJ Case Rep. 2019 May 15;12(5). pii: e228050. doi: 10.1136/bcr-2018-228050.

PMID:
31092482
16.

Non-canonical ubiquitination of the cholesterol-regulated degron of squalene monooxygenase.

Chua NK, Hart-Smith G, Brown AJ.

J Biol Chem. 2019 May 17;294(20):8134-8147. doi: 10.1074/jbc.RA119.007798. Epub 2019 Apr 2.

PMID:
30940729
17.

Impact of combined plaque structural stress and wall shear stress on coronary plaque progression, regression, and changes in composition.

Costopoulos C, Timmins LH, Huang Y, Hung OY, Molony DS, Brown AJ, Davis EL, Teng Z, Gillard JH, Samady H, Bennett MR.

Eur Heart J. 2019 Mar 21. pii: ehz132. doi: 10.1093/eurheartj/ehz132. [Epub ahead of print]

18.

Adaptations to Coronary Physiology in a Patient With Severe Aortic Stenosis and Complete Heart Block Undergoing Transcatheter Aortic Valve Replacement.

Michail M, Asrress KN, Cameron JD, Gooley R, McCormick LM, Hughes AD, Brown AJ.

JACC Cardiovasc Interv. 2019 Apr 8;12(7):687-689. doi: 10.1016/j.jcin.2019.01.215. Epub 2019 Mar 13. No abstract available.

PMID:
30878477
19.

Requirements for Portable Instrument Suites during Human Scientific Exploration of Mars.

Sehlke A, Mirmalek Z, Burtt D, Haberle CW, Santiago-Materese D, Kobs Nawotniak SE, Hughes SS, Garry WB, Bramall N, Brown AJ, Heldmann JL, Lim DSS.

Astrobiology. 2019 Mar;19(3):401-425. doi: 10.1089/ast.2018.1841.

20.

Glyoxylate cycle gene ICL1 is essential for the metabolic flexibility and virulence of Candida glabrata.

Chew SY, Ho KL, Cheah YK, Ng TS, Sandai D, Brown AJP, Than LTL.

Sci Rep. 2019 Feb 26;9(1):2843. doi: 10.1038/s41598-019-39117-1.

21.

Recurrent Noncoding Mutations in Skin Cancers: UV Damage Susceptibility or Repair Inhibition as Primary Driver?

Roberts SA, Brown AJ, Wyrick JJ.

Bioessays. 2019 Mar;41(3):e1800152. doi: 10.1002/bies.201800152. Epub 2019 Feb 25.

PMID:
30801747
22.

The shape of human squalene epoxidase expands the arsenal against cancer.

Brown AJ, Chua NK, Yan N.

Nat Commun. 2019 Feb 21;10(1):888. doi: 10.1038/s41467-019-08866-y. Review.

23.

Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.

Dong J, Du X, Wang H, Wang J, Lu C, Chen X, Zhu Z, Luo Z, Yu L, Brown AJ, Yang H, Wu JW.

Nat Commun. 2019 Feb 19;10(1):829. doi: 10.1038/s41467-019-08791-0.

24.

CHO genome mining for synthetic promoter design.

Johari YB, Brown AJ, Alves CS, Zhou Y, Wright CM, Estes SD, Kshirsagar R, James DC.

J Biotechnol. 2019 Mar 20;294:1-13. doi: 10.1016/j.jbiotec.2019.01.015. Epub 2019 Jan 28.

PMID:
30703471
25.

Off- vs. On-Pump Coronary Artery Bypass Grafting Long-Term Survival is Driven by Incompleteness of Revascularisation.

Thakur U, Nerlekar N, Muthalaly RG, Comella A, Wong NC, Cameron JD, Harper RW, Smith JA, Brown AJ.

Heart Lung Circ. 2018 Dec 13. pii: S1443-9506(18)32006-7. doi: 10.1016/j.hlc.2018.11.019. [Epub ahead of print]

PMID:
30686645
26.

A detour to sterol synthesis.

Baker MAB, Brown AJ.

Nat Microbiol. 2019 Feb;4(2):214-215. doi: 10.1038/s41564-018-0347-8. No abstract available.

PMID:
30675031
27.

Application of the DILEMMA score to improve lesion selection for invasive physiological assessment.

Michail M, Dehbi HM, Nerlekar N, Davies JE, Sharp ASP, Talwar S, Cameron JD, Brown AJ, Wong DT, Mathur A, Hughes AD, Narayan O.

Catheter Cardiovasc Interv. 2019 Jan 2. doi: 10.1002/ccd.28054. [Epub ahead of print]

PMID:
30604558
28.

ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2).

Wang H, Ma Q, Qi Y, Dong J, Du X, Rae J, Wang J, Wu WF, Brown AJ, Parton RG, Wu JW, Yang H.

Mol Cell. 2019 Feb 7;73(3):458-473.e7. doi: 10.1016/j.molcel.2018.11.014. Epub 2018 Dec 20.

PMID:
30581148
29.

Biodegradable-polymer versus polymer-free drug eluting stents for the treatment of coronary artery disease.

Nogic J, Thein P, Mirzaee S, Comella A, Soon K, Cameron JD, West NEJ, Brown AJ.

Cardiovasc Revasc Med. 2018 Dec 14. pii: S1553-8389(18)30613-4. doi: 10.1016/j.carrev.2018.12.010. [Epub ahead of print]

PMID:
30578169
30.

Association of Volumetric Epicardial Adipose Tissue Quantification and Cardiac Structure and Function.

Nerlekar N, Muthalaly RG, Wong N, Thakur U, Wong DTL, Brown AJ, Marwick TH.

J Am Heart Assoc. 2018 Dec 4;7(23):e009975. doi: 10.1161/JAHA.118.009975.

31.

Periprocedural Myocardial Injury Predicts Short- and Long-Term Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement.

Michail M, Cameron JN, Nerlekar N, Ihdayhid AR, McCormick LM, Gooley R, Niccoli G, Crea F, Montone RA, Brown AJ.

Circ Cardiovasc Interv. 2018 Nov;11(11):e007106. doi: 10.1161/CIRCINTERVENTIONS.118.007106.

PMID:
30571209
32.

Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation.

Sharpe LJ, Howe V, Scott NA, Luu W, Phan L, Berk JM, Hochstrasser M, Brown AJ.

J Biol Chem. 2019 Feb 15;294(7):2436-2448. doi: 10.1074/jbc.RA118.005069. Epub 2018 Dec 13.

PMID:
30545937
33.

Murine Models of Intraperitoneal Perfusion for Disseminated Colorectal Cancer.

McCabe-Lankford E, Peterson M, McCarthy B, Brown AJ, Terry B, Galarza-Paez L, Levi-Polyachenko N.

J Surg Res. 2019 Jan;233:310-322. doi: 10.1016/j.jss.2018.07.063. Epub 2018 Sep 5.

PMID:
30502264
34.

Memory in Fungal Pathogens Promotes Immune Evasion, Colonisation, and Infection.

Brown AJP, Gow NAR, Warris A, Brown GD.

Trends Microbiol. 2019 Mar;27(3):219-230. doi: 10.1016/j.tim.2018.11.001. Epub 2018 Nov 30. Review.

PMID:
30509563
35.

Nucleosome positions establish an extended mutation signature in melanoma.

Brown AJ, Mao P, Smerdon MJ, Wyrick JJ, Roberts SA.

PLoS Genet. 2018 Nov 28;14(11):e1007823. doi: 10.1371/journal.pgen.1007823. eCollection 2018 Nov.

36.

Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling.

Pradhan A, Avelar GM, Bain JM, Childers DS, Larcombe DE, Netea MG, Shekhova E, Munro CA, Brown GD, Erwig LP, Gow NAR, Brown AJP.

MBio. 2018 Nov 6;9(6). pii: e01318-18. doi: 10.1128/mBio.01318-18.

37.

Clinical outcomes of bioresorbable vascular scaffolds implanted with routine versus selective optical coherence tomography guidance: results from a single-centre experience.

Floré V, Brown AJ, Giblett JP, Liou K, Cranley J, Hoole SP, West NEJ.

EuroIntervention. 2019 Apr 20;14(17):1776-1783. doi: 10.4244/EIJ-D-18-00262.

38.

Whole synthetic pathway engineering of recombinant protein production.

Brown AJ, Gibson SJ, Hatton D, Arnall CL, James DC.

Biotechnol Bioeng. 2019 Feb;116(2):375-387. doi: 10.1002/bit.26855. Epub 2018 Nov 5.

PMID:
30345502
39.

Correction: Mallostery: Filling a niche between quality and metabolic control.

Chua NK, Brown AJ.

J Biol Chem. 2018 Oct 19;293(42):16176. doi: 10.1074/jbc.AAC118.006017. No abstract available.

40.

The effect of combined ezetimibe and statin therapy versus statin therapy alone on coronary plaque volume assessed by intravascular ultrasound: A systematic review and meta-analysis.

Mirzaee S, Thein PM, Nogic J, Nerlekar N, Nasis A, Brown AJ.

J Clin Lipidol. 2018 Sep - Oct;12(5):1133-1140.e15. doi: 10.1016/j.jacl.2018.06.001. Epub 2018 Jun 13. Review.

PMID:
30318063
41.

The dispersion-brightness relation for fast radio bursts from a wide-field survey.

Shannon RM, Macquart JP, Bannister KW, Ekers RD, James CW, Osłowski S, Qiu H, Sammons M, Hotan AW, Voronkov MA, Beresford RJ, Brothers M, Brown AJ, Bunton JD, Chippendale AP, Haskins C, Leach M, Marquarding M, McConnell D, Pilawa MA, Sadler EM, Troup ER, Tuthill J, Whiting MT, Allison JR, Anderson CS, Bell ME, Collier JD, Gürkan G, Heald G, Riseley CJ.

Nature. 2018 Oct;562(7727):386-390. doi: 10.1038/s41586-018-0588-y. Epub 2018 Oct 10.

PMID:
30305732
42.

Structure-Activity Relationship of the GPR55 Antagonist, CID16020046.

Brown AJ, Castellano-Pellicena I, Haslam CP, Nichols PL, Dowell SJ.

Pharmacology. 2018;102(5-6):324-331. doi: 10.1159/000493490. Epub 2018 Oct 8.

PMID:
30296786
43.

Specificity of the osmotic stress response in Candida albicans highlighted by quantitative proteomics.

Jacobsen MD, Beynon RJ, Gethings LA, Claydon AJ, Langridge JI, Vissers JPC, Brown AJP, Hammond DE.

Sci Rep. 2018 Sep 27;8(1):14492. doi: 10.1038/s41598-018-32792-6.

44.

Mallostery: Filling a niche between quality and metabolic control.

Chua NK, Brown AJ.

J Biol Chem. 2018 Sep 21;293(38):14951-14952. doi: 10.1074/jbc.H118.005031. Erratum in: J Biol Chem. 2018 Oct 19;293(42):16176.

45.

Author Correction: Drug-mediated metabolic tipping between antibiotic resistant states in a mixed-species community.

Beardmore RE, Cook E, Nilsson S, Smith AR, Tillmann A, Esquivel BD, Haynes K, Gow NAR, Brown AJP, White TC, Gudelj I.

Nat Ecol Evol. 2018 Nov;2(11):1824. doi: 10.1038/s41559-018-0678-0.

PMID:
30237543
46.

Clinical Sequelae of Leaflet Thrombosis Following Transcatheter Aortic Valve Replacement at Medium-Term Follow-Up.

Rashid HN, Nasis A, Gooley RP, Cameron JD, Brown AJ.

JACC Cardiovasc Interv. 2018 Sep 24;11(18):1904. doi: 10.1016/j.jcin.2018.07.006. No abstract available.

PMID:
30236367
47.

The prevalence of computed tomography-defined leaflet thrombosis in intra- versus supra-annular transcatheter aortic valve prostheses.

Rashid HN, Nasis A, Gooley RP, Cameron JD, Brown AJ.

Catheter Cardiovasc Interv. 2018 Dec 1;92(7):1414-1416. doi: 10.1002/ccd.27702. Epub 2018 Sep 14.

PMID:
30218474
48.

Subchondral Pathology: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle.

Shimozono Y, Brown AJ, Batista JP, Murawski CD, Gomaa M, Kong SW, Vaseenon T, Takao M, Glazebrook M; International Consensus Group on Cartilage Repair of the Ankle.

Foot Ankle Int. 2018 Jul;39(1_suppl):48S-53S. doi: 10.1177/1071100718781866.

PMID:
30215311
49.

Parp3 promotes long-range end joining in murine cells.

Layer JV, Cleary JP, Brown AJ, Stevenson KE, Morrow SN, Van Scoyk A, Blasco RB, Karaca E, Meng FL, Frock RL, Tivey T, Kim S, Fuchs H, Chiarle R, Alt FW, Roberts SA, Weinstock DM, Day TA.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10076-10081. doi: 10.1073/pnas.1801591115. Epub 2018 Sep 13.

50.

The earlier the better: the role of palliative care consultation on aggressive end of life care, hospice utilization, and advance care planning documentation among gynecologic oncology patients.

Schneiter MK, Karlekar MB, Crispens MA, Prescott LS, Brown AJ.

Support Care Cancer. 2019 May;27(5):1927-1934. doi: 10.1007/s00520-018-4457-x. Epub 2018 Sep 12.

PMID:
30209601

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