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Items: 44

1.

Assessment of the abuse liability of ABT-288, a novel histamine H₃ receptor antagonist.

Hudzik TJ, Basso A, Boyce-Rustay JM, Bracken W, Browman KE, Drescher K, Esbenshade TA, Loberg LI, Lynch JJ 3rd, Brioni JD.

Psychopharmacology (Berl). 2013 Jul;228(2):187-97. doi: 10.1007/s00213-013-3027-7. Epub 2013 Feb 28.

PMID:
23455597
2.

PARP inhibitors attenuate chemotherapy-induced painful neuropathy.

Brederson JD, Joshi SK, Browman KE, Mikusa J, Zhong C, Gauvin D, Liu X, Shi Y, Penning TD, Shoemaker AR, Giranda VL.

J Peripher Nerv Syst. 2012 Sep;17(3):324-30. doi: 10.1111/j.1529-8027.2012.00413.x.

PMID:
22971094
3.

Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist.

Esbenshade TA, Browman KE, Miller TR, Krueger KM, Komater-Roderwald V, Zhang M, Fox GB, Rueter L, Robb HM, Radek RJ, Drescher KU, Fey TA, Bitner RS, Marsh K, Polakowski JS, Zhao C, Cowart MD, Hancock AA, Sullivan JP, Brioni JD.

J Pharmacol Exp Ther. 2012 Oct;343(1):233-45. doi: 10.1124/jpet.112.194126. Epub 2012 Jul 19.

4.

Acute inhibition of 11beta-hydroxysteroid dehydrogenase type-1 improves memory in rodent models of cognition.

Mohler EG, Browman KE, Roderwald VA, Cronin EA, Markosyan S, Scott Bitner R, Strakhova MI, Drescher KU, Hornberger W, Rohde JJ, Brune ME, Jacobson PB, Rueter LE.

J Neurosci. 2011 Apr 6;31(14):5406-13. doi: 10.1523/JNEUROSCI.4046-10.2011.

5.

Cued and Contextual Fear Conditioning for Rodents.

Curzon P, Rustay NR, Browman KE.

In: Buccafusco JJ, editor. Methods of Behavior Analysis in Neuroscience. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2009. Chapter 2.

6.

Behavioral characterization of a mutant mouse strain lacking D-amino acid oxidase activity.

Zhang M, Ballard ME, Basso AM, Bratcher N, Browman KE, Curzon P, Konno R, Meyer AH, Rueter LE.

Behav Brain Res. 2011 Feb 2;217(1):81-7. doi: 10.1016/j.bbr.2010.09.030. Epub 2010 Oct 7.

PMID:
20933022
7.

Design, synthesis and evaluation of constrained tetrahydroimidazopyrimidine derivatives as antagonists of corticotropin-releasing factor type 1 receptor (CRF1R).

Vrudhula VM, Dasgupta B, Pin SS, Burris KD, Balanda LA, Fung LK, Fiedler T, Browman KE, Taber MT, Zhang J, Macor JE, Dubowchik GM.

Bioorg Med Chem Lett. 2010 Mar 15;20(6):1905-9. doi: 10.1016/j.bmcl.2010.01.127. Epub 2010 Feb 4.

PMID:
20185312
8.

ABT-594 improves performance in the 5-choice serial reaction time task under conditions of increased difficulty, sub-chronic dosing, and in poorly-performing subjects.

Mohler EG, Franklin SR, Rueter LE, Fox GB, Decker MW, Browman KE.

Pharmacol Biochem Behav. 2010 Apr;95(2):146-57. doi: 10.1016/j.pbb.2009.12.019. Epub 2010 Jan 11.

PMID:
20064548
9.

Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease.

Rustay NR, Cronin EA, Curzon P, Markosyan S, Bitner RS, Ellis TA, Waring JF, Decker MW, Rueter LE, Browman KE.

Brain Res. 2010 Jan 22;1311:136-47. doi: 10.1016/j.brainres.2009.11.040. Epub 2009 Nov 26.

PMID:
19944081
10.

Use of the H3 receptor antagonist radioligand [3H]-A-349821 to reveal in vivo receptor occupancy of cognition enhancing H3 receptor antagonists.

Miller TR, Milicic I, Bauch J, Du J, Surber B, Browman KE, Marsh K, Cowart M, Brioni JD, Esbenshade TA.

Br J Pharmacol. 2009 May;157(1):139-49. doi: 10.1111/j.1476-5381.2009.00239.x.

11.

The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.

Zhao C, Sun M, Bennani YL, Gopalakrishnan SM, Witte DG, Miller TR, Krueger KM, Browman KE, Thiffault C, Wetter J, Marsh KC, Hancock AA, Esbenshade TA, Cowart MD.

J Med Chem. 2008 Sep 11;51(17):5423-30. doi: 10.1021/jm8003625. Epub 2008 Aug 7.

PMID:
18683917
12.

Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties.

Tietje KR, Anderson DJ, Bitner RS, Blomme EA, Brackemeyer PJ, Briggs CA, Browman KE, Bury D, Curzon P, Drescher KU, Frost JM, Fryer RM, Fox GB, Gronlien JH, Håkerud M, Gubbins EJ, Halm S, Harris R, Helfrich RJ, Kohlhaas KL, Law D, Malysz J, Marsh KC, Martin RL, Meyer MD, Molesky AL, Nikkel AL, Otte S, Pan L, Puttfarcken PS, Radek RJ, Robb HM, Spies E, Thorin-Hagene K, Waring JF, Ween H, Xu H, Gopalakrishnan M, Bunnelle WH.

CNS Neurosci Ther. 2008 Spring;14(1):65-82. doi: 10.1111/j.1527-3458.2008.00037.x. Review.

PMID:
18482100
13.

The histamine H3 receptor: an attractive target for the treatment of cognitive disorders.

Esbenshade TA, Browman KE, Bitner RS, Strakhova M, Cowart MD, Brioni JD.

Br J Pharmacol. 2008 Jul;154(6):1166-81. doi: 10.1038/bjp.2008.147. Epub 2008 May 12. Review.

14.

Minimization of potential hERG liability in histamine H3 receptor antagonists.

Black LA, Liu H, Diaz GJ, Fox GB, Browman KE, Wetter J, Marsh KC, Miller TR, Esbenshade TA, Brioni J, Cowart MD.

Inflamm Res. 2008;57 Suppl 1:S45-6. doi: 10.1007/s00011-007-0622-2. No abstract available.

PMID:
18345496
15.

Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.

Altenbach RJ, Liu H, Banfor PN, Browman KE, Fox GB, Fryer RM, Komater VA, Krueger KM, Marsh K, Miller TR, Pan JB, Pan L, Sun M, Thiffault C, Wetter J, Zhao C, Zhou D, Esbenshade TA, Hancock AA, Cowart MD.

J Med Chem. 2007 Nov 1;50(22):5439-48. Epub 2007 Oct 6.

PMID:
17918921
16.

Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity.

Cowart M, Gfesser GA, Browman KE, Faghih R, Miller TR, Milicic I, Baranowski JL, Krueger KM, Witte DG, Molesky AL, Komater VA, Buckley MJ, Diaz GJ, Gagne GD, Zhou D, Deng X, Pan L, Roberts EM, Diehl MS, Wetter JM, Marsh KC, Fox GB, Brioni JD, Esbenshade TA, Hancock AA.

Biochem Pharmacol. 2007 Apr 15;73(8):1243-55. Epub 2007 Feb 23.

PMID:
17371699
17.

An orally active corticotropin releasing factor 1 receptor antagonist from 8-aryl-1,3a,7,8-tetraaza-cyclopenta[a]indenes.

Han X, Civiello R, Pin SS, Burris K, Balanda LA, Knipe J, Ren S, Fiedler T, Browman KE, Macci R, Taber MT, Zhang J, Dubowchik GM.

Bioorg Med Chem Lett. 2007 Apr 1;17(7):2026-30. Epub 2007 Jan 13.

PMID:
17258456
18.

The drug-induced helplessness test: an animal assay for assessing behavioral despair in response to neuroleptic treatment.

Ballard ME, Basso AM, Gallagher KB, Browman KE, Fox GB, Drescher KU, Gross G, Decker MW, Rueter LE, Zhang M.

Psychopharmacology (Berl). 2007 Jan;190(1):1-11. Epub 2006 Nov 9.

PMID:
17093979
19.

Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats.

Zhang M, Ballard ME, Kohlhaas KL, Browman KE, Jongen-Rêlo AL, Unger LV, Fox GB, Gross G, Decker MW, Drescher KU, Rueter LE.

Neuropsychopharmacology. 2006 Jul;31(7):1382-92. Epub 2005 Dec 14.

20.

A-412997, a selective dopamine D4 agonist, improves cognitive performance in rats.

Browman KE, Curzon P, Pan JB, Molesky AL, Komater VA, Decker MW, Brioni JD, Moreland RB, Fox GB.

Pharmacol Biochem Behav. 2005 Sep;82(1):148-55. Epub 2005 Sep 8.

PMID:
16154186
21.

Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists.

Han X, Michne JA, Pin SS, Burris KD, Balanda LA, Fung LK, Fiedler T, Browman KE, Taber MT, Zhang J, Dubowchik GM.

Bioorg Med Chem Lett. 2005 Sep 1;15(17):3870-3.

PMID:
15990298
22.

Selective H3 receptor (H3R) blockade: broad efficacy in cognition and schizophrenia.

Fox GB, Esbenshade TA, Pan JB, Browman KE, Zhang M, Ballard ME, Radek RJ, Miner H, Bitner RS, Krueger KM, Yao BB, Faghih R, Rueter LE, Komater VA, Drescher KU, Buckley MJ, Sullivan JP, Cowart MD, Decker MW, Hancock AA.

Inflamm Res. 2005 Apr;54 Suppl 1:S23-4. No abstract available.

PMID:
15928819
23.

Effects of histamine H3 receptor antagonists in two models of spatial learning.

Komater VA, Buckley MJ, Browman KE, Pan JB, Hancock AA, Decker MW, Fox GB.

Behav Brain Res. 2005 Apr 30;159(2):295-300. Epub 2004 Dec 10.

PMID:
15817192
24.

Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist.

Fox GB, Esbenshade TA, Pan JB, Radek RJ, Krueger KM, Yao BB, Browman KE, Buckley MJ, Ballard ME, Komater VA, Miner H, Zhang M, Faghih R, Rueter LE, Bitner RS, Drescher KU, Wetter J, Marsh K, Lemaire M, Porsolt RD, Bennani YL, Sullivan JP, Cowart MD, Decker MW, Hancock AA.

J Pharmacol Exp Ther. 2005 Apr;313(1):176-90. Epub 2004 Dec 17.

25.

Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan.

Browman KE, Komater VA, Curzon P, Rueter LE, Hancock AA, Decker MW, Fox GB.

Behav Brain Res. 2004 Aug 12;153(1):69-76.

PMID:
15219708
26.

Cognition enhancing effects of novel H(3) receptor (H(3)R) antagonists in several animal models.

Fox GB, Pan JB, Lewis AM, Browman KE, Komater VA, Buckley MJ, Curzon P, Radek RJ, Faghih R, Esbenshade TA, Cowart MD, Decker MW, Hancock AA.

Inflamm Res. 2004 Mar;53 Suppl 1:S49-50. Epub 2004 Mar 5. No abstract available.

PMID:
15054614
27.

2-arylaminothiazoles as high-affinity corticotropin-releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy.

Dubowchik GM, Michne JA, Zuev D, Schwartz W, Scola PM, James CA, Ruediger EH, Pin SS, Burris KD, Balanda LA, Gao Q, Wu D, Fung L, Fiedler T, Browman KE, Taber MT, Zhang J.

Bioorg Med Chem Lett. 2003 Nov 17;13(22):3997-4000.

PMID:
14592493
28.

H3 receptor blockade by thioperamide enhances cognition in rats without inducing locomotor sensitization.

Komater VA, Browman KE, Curzon P, Hancock AA, Decker MW, Fox GB.

Psychopharmacology (Berl). 2003 Jun;167(4):363-72. Epub 2003 Apr 8.

PMID:
12682709
29.

Sensitivity and tolerance to ethanol-induced incoordination and hypothermia in HAFT and LAFT mice.

Rustay NR, Boehm SL 2nd, Schafer GL, Browman KE, Erwin VG, Crabbe JC.

Pharmacol Biochem Behav. 2001 Sep;70(1):167-74.

PMID:
11566154
30.

Sensitivity and tolerance to ethanol in mouse lines selected for ethanol-induced hypothermia.

Browman KE, Rustay NR, Nikolaidis N, Crawshaw L, Crabbe JC.

Pharmacol Biochem Behav. 2000 Dec;67(4):821-9.

PMID:
11166073
31.

Environmental modulation of the response to amphetamine: dissociation between changes in behavior and changes in dopamine and glutamate overflow in the rat striatal complex.

Badiani A, Oates MM, Fraioli S, Browman KE, Ostrander MM, Xue CJ, Wolf ME, Robinson TE.

Psychopharmacology (Berl). 2000 Aug;151(2-3):166-74.

32.
33.
34.

Quantitative trait loci affecting ethanol sensitivity in BXD recombinant inbred mice.

Browman KE, Crabbe JC.

Alcohol Clin Exp Res. 2000 Jan;24(1):17-23. Erratum in: Alcohol Clin Exp Res 2002 May;26(5):704.

PMID:
10656187
35.

Alcohol and genetics: new animal models.

Browman KE, Crabbe JC.

Mol Med Today. 1999 Jul;5(7):310-8. Review.

PMID:
10377523
36.
37.

Injection of the protein kinase C inhibitor Ro31-8220 into the nucleus accumbens attenuates the acute response to amphetamine: tissue and behavioral studies.

Browman KE, Kantor L, Richardson S, Badiani A, Robinson TE, Gnegy ME.

Brain Res. 1998 Dec 14;814(1-2):112-9.

PMID:
9838071
38.
39.

Modulation of the induction or expression of psychostimulant sensitization by the circumstances surrounding drug administration.

Robinson TE, Browman KE, Crombag HS, Badiani A.

Neurosci Biobehav Rev. 1998 Mar;22(2):347-54. Review.

PMID:
9579324
40.

Fimbria-fornix lesions do not block sensitization to the psychomotor activating effects of amphetamine.

Browman KE, Badiani A, Robinson TE.

Pharmacol Biochem Behav. 1996 Apr;53(4):899-902.

PMID:
8801595
41.
43.

Alternating prism exposure causes dual adaptation and generalization to a novel displacement.

Welch RB, Bridgeman B, Anand S, Browman KE.

Percept Psychophys. 1993 Aug;54(2):195-204.

PMID:
8361835
44.

Napping and 24-hour sleep/wake patterns in healthy elderly and young adults.

Buysse DJ, Browman KE, Monk TH, Reynolds CF 3rd, Fasiczka AL, Kupfer DJ.

J Am Geriatr Soc. 1992 Aug;40(8):779-86.

PMID:
1634721

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