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A joint effort: The interplay between the innate and the adaptive immune system in Lyme arthritis.

Brouwer MAE, van de Schoor FR, Vrijmoeth HD, Netea MG, Joosten LAB.

Immunol Rev. 2020 Jan 13. doi: 10.1111/imr.12837. [Epub ahead of print] Review.


Diagnostic performance of the basic and advanced life support termination of resuscitation rules: A systematic review and diagnostic meta-analysis.

Nas J, Kleinnibbelink G, Hannink G, Navarese EP, van Royen N, de Boer MJ, Wik L, Bonnes JL, Brouwer MA.

Resuscitation. 2019 Dec 28;148:3-13. doi: 10.1016/j.resuscitation.2019.12.016. [Epub ahead of print] Review.


Meta-Analysis Comparing Cardiac Arrest Outcomes Before and After Resuscitation Guideline Updates.

Nas J, Te Grotenhuis R, Bonnes JL, Furlaneto JM, van Royen N, Smeets JLRM, de Boer MJ, Navarese EP, Brouwer MA.

Am J Cardiol. 2020 Feb 15;125(4):618-629. doi: 10.1016/j.amjcard.2019.11.007. Epub 2019 Nov 20.


Effect of Face-to-Face vs Virtual Reality Training on Cardiopulmonary Resuscitation Quality: A Randomized Clinical Trial.

Nas J, Thannhauser J, Vart P, van Geuns RJ, Muijsers HEC, Mol JQ, Aarts GWA, Konijnenberg LSF, Gommans DHF, Ahoud-Schoenmakers SGAM, Vos JL, van Royen N, Bonnes JL, Brouwer MA.

JAMA Cardiol. 2019 Nov 17. doi: 10.1001/jamacardio.2019.4992. [Epub ahead of print]


Comparing thoracoabdominal injuries of manual versus load-distributing band cardiopulmonary resuscitation.

Sonnemans LJP, Bayat AR, Bruinen ARC, van Wely MH, Brouwer MA, Bosboom D, van der Hoeven JG, Prokop M, Klein WM.

Eur J Emerg Med. 2019 Nov 7. doi: 10.1097/MEJ.0000000000000642. [Epub ahead of print]


Multi-Site Coronary Vein Sampling Study on Cardiac Troponin T Degradation in Non-ST-Segment-Elevation Myocardial Infarction: Toward a More Specific Cardiac Troponin T Assay.

Damen SAJ, Vroemen WHM, Brouwer MA, Mezger STP, Suryapranata H, van Royen N, Bekers O, Meex SJR, Wodzig WKWH, Verheugt FWA, de Boer D, Cramer GE, Mingels AMA.

J Am Heart Assoc. 2019 Jul 16;8(14):e012602. doi: 10.1161/JAHA.119.012602. Epub 2019 Jul 4.


Cardiac troponin I is present in plasma of type 1 myocardial infarction patients and patients with troponin I elevations due to other etiologies as complex with little free I.

van Wijk XMR, Claassen S, Enea NS, Li P, Yang S, Brouwer MA, Cramer GE, Zuk R, Lynch KL, Wu AHB.

Clin Biochem. 2019 Nov;73:35-43. doi: 10.1016/j.clinbiochem.2019.06.012. Epub 2019 Jun 25.


Association between Lifelong Physical Activity and Disease Characteristics in HCM.

Aengevaeren VL, Gommans DHF, Dieker HJ, Timmermans J, Verheugt FWA, Bakker J, Hopman MTE, DE Boer MJ, Brouwer MA, Thompson PD, Kofflard MJM, Cramer GE, Eijsvogels TMH.

Med Sci Sports Exerc. 2019 Oct;51(10):1995-2002. doi: 10.1249/MSS.0000000000002015.


The ventricular fibrillation waveform in relation to shock success in early vs. late phases of out-of-hospital resuscitation.

Thannhauser J, Nas J, van Grunsven PM, Meinsma G, Zwart HJ, de Boer MJ, van Royen N, Bonnes JL, Brouwer MA.

Resuscitation. 2019 Jun;139:99-105. doi: 10.1016/j.resuscitation.2019.04.010. Epub 2019 Apr 15.


Importance of the distinction between recurrent and shock-resistant ventricular fibrillation: Call for a uniform definition of refractory VF.

Nas J, Thannhauser J, Bonnes JL, Brouwer MA.

Resuscitation. 2019 May;138:312-313. doi: 10.1016/j.resuscitation.2019.01.042. Epub 2019 Mar 12. No abstract available.


Reply to the letter by Calle and Mpotos: Why not try harder to prove that automated external defibrillators save lives?

Nas J, Thannhauser J, de Boer MJ, Bonnes JL, Brouwer MA.

Neth Heart J. 2019 Apr;27(4):224-225. doi: 10.1007/s12471-019-1249-y. No abstract available.


Outcomes of apixaban versus warfarin in patients with atrial fibrillation and multi-morbidity: Insights from the ARISTOTLE trial.

Alexander KP, Brouwer MA, Mulder H, Vinereanu D, Lopes RD, Proietti M, Al-Khatib SM, Hijazi Z, Halvorsen S, Hylek EM, Verheugt FWA, Alexander JH, Wallentin L, Granger CB; ARISTOTLE Investigators.

Am Heart J. 2019 Feb;208:123-131. doi: 10.1016/j.ahj.2018.09.017. Epub 2018 Nov 22.


[Weight-dependent dosing of aspirin; the pharmacological and cardiological perspective].

Damen SAJ, Brouwer MA, Kramers C.

Ned Tijdschr Geneeskd. 2018 Nov 21;162. pii: D3298. Dutch.


Uninterrupted anticoagulation with non-vitamin K antagonist oral anticoagulants in atrial fibrillation catheter ablation: Lessons learned from randomized trials.

Cardoso R, Willems S, Gerstenfeld EP, Verma A, Schilling R, Hohnloser SH, Okumura K, Nordaby M, Brouwer MA, Calkins H.

Clin Cardiol. 2019 Jan;42(1):198-205. doi: 10.1002/clc.23120. Epub 2018 Dec 7. Review.


Clofazimine does not lead to significant QT interval prolongation: a multicentre study.

Zweijpfenning SMH, van Groningen H, van Ingen J, Magis-Escurra C, Boeree MJ, Wagner D, Bax H, Andrejak C, Wener R, Rahman A, Kunst H, Lorent N, Brouwer MA, Hoefsloot W; NTM-NET.

Eur Respir J. 2018 Nov 1;52(5). pii: 1801386. doi: 10.1183/13993003.01386-2018. Print 2018 Nov. No abstract available.


Feasibility and Outcomes of Transcatheter Aortic Valve Implantation Using the Left Axillary Artery as Primary Access Site.

van der Wulp K, Verkroost MWA, van Wely MH, Gehlmann HR, Van Garsse LAFM, Noyez L, Brouwer MA, Kievit PC, De Boer MJ, Suryapranata H, Morshuis WJ, van Royen N.

Ann Thorac Surg. 2019 Feb;107(2):546-552. doi: 10.1016/j.athoracsur.2018.07.093. Epub 2018 Oct 4.


Changes in automated external defibrillator use and survival after out-of-hospital cardiac arrest in the Nijmegen area.

Nas J, Thannhauser J, Herrmann JJ, van der Wulp K, van Grunsven PM, van Royen N, de Boer MJ, Bonnes JL, Brouwer MA.

Neth Heart J. 2018 Dec;26(12):600-605. doi: 10.1007/s12471-018-1162-9.


A multi-site coronary sampling study on CRP in non-STEMI: Novel insights into the inflammatory process in acute coronary syndromes.

Damen SAJ, Cramer GE, Dieker HJ, Gehlmann H, Aengevaeren WRM, Oude Ophuis TJM, Fokkert MJ, Dikkeschei LD, Vroemen WHM, Verheugt FWA, Brouwer MA, Suryapranata H.

Atherosclerosis. 2018 Nov;278:117-123. doi: 10.1016/j.atherosclerosis.2018.09.024. Epub 2018 Sep 19.


Baseline low-density lipoprotein cholesterol to predict the extent of cardiovascular benefit from lipid-lowering therapies: a review.

Navarese EP, Andreotti F, Raggi P, Kolodziejczak M, Buffon A, Bliden K, Tantry U, Kubica J, Sardella G, Lauten A, Agewall S, Gurbel PA, Brouwer MA.

Eur Heart J Cardiovasc Pharmacother. 2019 Jan 1;5(1):47-54. doi: 10.1093/ehjcvp/pvy038. Review.


Prediction of Extensive Myocardial Fibrosis in Nonhigh Risk Patients With Hypertrophic Cardiomyopathy.

Gommans DHF, Cramer GE, Fouraux MA, Bakker J, Michels M, Dieker HJ, Timmermans J, Marcelis CLM, Verheugt FWA, de Boer MJ, Kofflard MJM, de Boer RA, Brouwer MA.

Am J Cardiol. 2018 Aug 1;122(3):483-489. doi: 10.1016/j.amjcard.2018.04.020. Epub 2018 May 1.


Second-generation cryoballoon ablation for recurrent atrial fibrillation after an index cryoballoon procedure: a staged strategy with variable balloon size.

Westra SW, van Vugt SPG, Sezer S, Evertz R, Hemels ME, Beukema RJ, de Asmundis C, Brouwer MA, Chierchia GB.

J Interv Card Electrophysiol. 2019 Jan;54(1):17-24. doi: 10.1007/s10840-018-0418-z. Epub 2018 Aug 8.


The stability of antimycobacterial drugs in media used for drug susceptibility testing.

Schoutrop ELM, Brouwer MAE, Jenniskens JCA, Ferro BE, Mouton JW, Aarnoutse RE, van Ingen J.

Diagn Microbiol Infect Dis. 2018 Dec;92(4):305-308. doi: 10.1016/j.diagmicrobio.2018.06.015. Epub 2018 Jun 27.


Periprocedural anticoagulation in atrial fibrillation: Update on electrical cardioversion and ablation.

van Vugt SPG, Brouwer MA.

Neth Heart J. 2018 Jun;26(6):352-360. doi: 10.1007/s12471-018-1119-z. Review.


Correction: A systematic review and meta-analysis of the protective effects of metformin in experimental myocardial infarction.

Hesen NA, Riksen NP, Aalders B, Brouwer MAE, Ritskes-Hoitinga M, El Messaoudi S, Wever KE.

PLoS One. 2018 Apr 9;13(4):e0195858. doi: 10.1371/journal.pone.0195858. eCollection 2018.


New plots in the partnerships of contemporary STEMI care: Revival of the 'ménage à trois'?

Brouwer MA, de Boer MJ.

Eur Heart J Acute Cardiovasc Care. 2018 Jan 1:2048872618757177. doi: 10.1177/2048872618757177. [Epub ahead of print] No abstract available.


[Trisomy 18: how lethal is 'lethal'?]

Brouwer MA, Maeckelberghe ELM, van der Hoeven MAFBM, Schutte J, Wee HL, Willekes C, Verhagen AAE.

Ned Tijdschr Geneeskd. 2017;161:D1716. Dutch.


High T2-weighted signal intensity for risk prediction of sudden cardiac death in hypertrophic cardiomyopathy.

Gommans DHF, Cramer GE, Bakker J, Dieker HJ, Michels M, Fouraux MA, Marcelis CLM, Verheugt FWA, Timmermans J, Brouwer MA, Kofflard MJM.

Int J Cardiovasc Imaging. 2018 Jan;34(1):113-120. doi: 10.1007/s10554-017-1252-6. Epub 2017 Oct 23.


A systematic review and meta-analysis of the protective effects of metformin in experimental myocardial infarction.

Hesen NA, Riksen NP, Aalders B, Brouwer MA, Ritskes-Hoitinga M, El Messaoudi S, Wever KE.

PLoS One. 2017 Aug 23;12(8):e0183664. doi: 10.1371/journal.pone.0183664. eCollection 2017. Review. Erratum in: PLoS One. 2018 Apr 9;13(4):e0195858.


Real-life use of Rivaroxaban in the Netherlands: data from the Xarelto for Prevention of Stroke in Patients with Atrial Fibrillation (XANTUS) registry.

Pisters R, van Vugt SPG, Brouwer MA, Elvan A, Ten Holt WL, Zwart PAG, Kirchhof P, Crijns HJGM, Hemels MEW.

Neth Heart J. 2017 Oct;25(10):551-558. doi: 10.1007/s12471-017-1009-9.


Mechanical CPR in refractory cardiac arrest may be practical, but injuries should be monitored: A concise meta-analysis.

den Uil CA, Bonnes JL, Brouwer MA.

Resuscitation. 2018 Jan;122:e5-e6. doi: 10.1016/j.resuscitation.2017.05.022. Epub 2017 May 27. No abstract available.


Off-Label Use of Non-Vitamin K Antagonist Oral Anticoagulants.

van Vugt SPG, Brouwer MA, Verheugt FWA.

J Am Coll Cardiol. 2017 May 23;69(20):2577-2578. doi: 10.1016/j.jacc.2017.01.073. No abstract available.


Letter by Damen et al Regarding Article, "A Critical Appraisal of Aspirin in Secondary Prevention: Is Less More?"

Damen SAJ, Brouwer MA, Verheugt FWA.

Circulation. 2017 May 9;135(19):e1035-e1036. doi: 10.1161/CIRCULATIONAHA.116.026985. No abstract available.


A systematic review of discomfort due to toe or ear clipping in laboratory rodents.

Wever KE, Geessink FJ, Brouwer MAE, Tillema A, Ritskes-Hoitinga M.

Lab Anim. 2017 Dec;51(6):583-600. doi: 10.1177/0023677217705912. Epub 2017 Apr 21. Review.


Observed survival benefit of mild therapeutic hypothermia reanalysing the Circulation Improving Resuscitation Care trial.

Nürnberger A, Herkner H, Sterz F, Olsen JA, Lozano M Jr, van Grunsven PM, Lerner EB, Persse D, Malzer R, Brouwer MA, Westfall M, Souders CM, Travis DT, Herken UR, Wik L.

Eur J Clin Invest. 2017 Jun;47(6):439-446. doi: 10.1111/eci.12759. Epub 2017 May 16.


Ventricular fibrillation waveform characteristics of the surface ECG: Impact of the left ventricular diameter and mass.

Bonnes JL, Thannhauser J, Nas J, Westra SW, Jansen RMG, Meinsma G, de Boer MJ, Smeets JLRM, Keuper W, Brouwer MA.

Resuscitation. 2017 Jun;115:82-89. doi: 10.1016/j.resuscitation.2017.03.029. Epub 2017 Mar 29.


Uninterrupted Dabigatran versus Warfarin for Ablation in Atrial Fibrillation.

Calkins H, Willems S, Gerstenfeld EP, Verma A, Schilling R, Hohnloser SH, Okumura K, Serota H, Nordaby M, Guiver K, Biss B, Brouwer MA, Grimaldi M; RE-CIRCUIT Investigators.

N Engl J Med. 2017 Apr 27;376(17):1627-1636. doi: 10.1056/NEJMoa1701005. Epub 2017 Mar 19.


High T2-weighted signal intensity is associated with elevated troponin T in hypertrophic cardiomyopathy.

Gommans DF, Cramer GE, Bakker J, Michels M, Dieker HJ, Timmermans J, Fouraux MA, Marcelis CL, Verheugt FW, Brouwer MA, Kofflard MJ.

Heart. 2017 Feb 15;103(4):293-299. doi: 10.1136/heartjnl-2016-309900. Epub 2016 Aug 9.


Randomized evaluation of short-term dual antiplatelet therapy in patients with acute coronary syndrome treated with the COMBO dual therapy stent: rationale and design of the REDUCE trial.

Camaro C, Damen SA, Brouwer MA, Kedhi E, Lee SW, Verdoia M, Barbieri L, Rognoni A, van T Hof AW, Ligtenberg E, de Boer MJ, Suryapranata H, De Luca G.

Am Heart J. 2016 Aug;178:37-44. doi: 10.1016/j.ahj.2016.04.016. Epub 2016 Apr 29.


Polypharmacy and effects of apixaban versus warfarin in patients with atrial fibrillation: post hoc analysis of the ARISTOTLE trial.

Jaspers Focks J, Brouwer MA, Wojdyla DM, Thomas L, Lopes RD, Washam JB, Lanas F, Xavier D, Husted S, Wallentin L, Alexander JH, Granger CB, Verheugt FW.

BMJ. 2016 Jun 15;353:i2868. doi: 10.1136/bmj.i2868.


Low performance of bleeding risk models in the very elderly with atrial fibrillation using vitamin K antagonists.

Jaspers Focks J, van Vugt SP, Albers-Akkers MT, Lamfers EJ, Bloem-de Vries LM, Verheugt FW, Brouwer MA.

J Thromb Haemost. 2016 Sep;14(9):1715-24. doi: 10.1111/jth.13361. Epub 2016 Jul 18.


Why do some studies find that CPR fraction is not a predictor of survival?

Wik L, Olsen JA, Persse D, Sterz F, Lozano M Jr, Brouwer MA, Westfall M, Souders CM, Travis DT, Herken UR, Lerner EB.

Resuscitation. 2016 Jul;104:59-62. doi: 10.1016/j.resuscitation.2016.04.013. Epub 2016 May 4.


Impact of the papillary muscles on cardiac magnetic resonance image analysis of important left ventricular parameters in hypertrophic cardiomyopathy.

Gommans DH, Bakker J, Cramer GE, Verheugt FW, Brouwer MA, Kofflard MJ.

Neth Heart J. 2016 May;24(5):326-31. doi: 10.1007/s12471-016-0805-y.


Risk Factors for Inadequate Defibrillation Safety Margins Vary With the Underlying Cardiac Disease: Implications for Selective Testing Strategies.

Bonnes JL, Westra SW, Bouwels LH, DE Boer MJ, Brouwer MA, Smeets JL.

J Cardiovasc Electrophysiol. 2016 May;27(5):587-93. doi: 10.1111/jce.12940. Epub 2016 Mar 9.


Termination of resuscitation in the prehospital setting: A comparison of decisions in clinical practice vs. recommendations of a termination rule.

Verhaert DV, Bonnes JL, Nas J, Keuper W, van Grunsven PM, Smeets JL, de Boer MJ, Brouwer MA.

Resuscitation. 2016 Mar;100:60-5. doi: 10.1016/j.resuscitation.2015.12.014. Epub 2016 Jan 13.


Manual Cardiopulmonary Resuscitation Versus CPR Including a Mechanical Chest Compression Device in Out-of-Hospital Cardiac Arrest: A Comprehensive Meta-analysis From Randomized and Observational Studies.

Bonnes JL, Brouwer MA, Navarese EP, Verhaert DV, Verheugt FW, Smeets JL, de Boer MJ.

Ann Emerg Med. 2016 Mar;67(3):349-360.e3. doi: 10.1016/j.annemergmed.2015.09.023. Epub 2015 Nov 19. Review.


Ventricular fibrillation waveform characteristics differ according to the presence of a previous myocardial infarction: A surface ECG study in ICD-patients.

Bonnes JL, Thannhauser J, Hermans MC, Westra SW, Oostendorp TF, Meinsma G, de Boer MJ, Brouwer MA, Smeets JL.

Resuscitation. 2015 Nov;96:239-45. doi: 10.1016/j.resuscitation.2015.08.014. Epub 2015 Aug 29.


Chest compression duration influences outcome between integrated load-distributing band and manual CPR during cardiac arrest.

Olsen JA, Lerner EB, Persse D, Sterz F, Lozano M Jr, Brouwer MA, Westfall M, van Grunsven PM, Travis DT, Herken UR, Brunborg C, Wik L.

Acta Anaesthesiol Scand. 2016 Feb;60(2):222-9. doi: 10.1111/aas.12605. Epub 2015 Aug 27.


Pre-shock chest compression pause effects on termination of ventricular fibrillation/tachycardia and return of organized rhythm within mechanical and manual cardiopulmonary resuscitation.

Olsen JA, Brunborg C, Steinberg M, Persse D, Sterz F, Lozano M Jr, Westfall M, Travis DT, Lerner EB, Brouwer MA, Wik L.

Resuscitation. 2015 Aug;93:158-63. doi: 10.1016/j.resuscitation.2015.04.023. Epub 2015 Apr 28.


Minimizing pre-shock chest compression pauses in a cardiopulmonary resuscitation cycle by performing an earlier rhythm analysis.

Steinberg MT, Olsen JA, Brunborg C, Persse D, Sterz F, Lozano M Jr, Brouwer MA, Westfall M, Souders CM, van Grunsven PM, Travis DT, Lerner EB, Wik L.

Resuscitation. 2015 Feb;87:33-7. doi: 10.1016/j.resuscitation.2014.11.012. Epub 2014 Nov 21.


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