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Items: 10

1.

A novel class of cardioprotective small-molecule PTP inhibitors.

Antonucci S, Di Sante M, Sileikyte J, Deveraux J, Bauer T, Bround MJ, Menabò R, Paillard M, Alanova P, Carraro M, Ovize M, Molkentin JD, Cohen M, Forte MA, Bernardi P, Di Lisa F, Murphy E.

Pharmacol Res. 2019 Nov 20;151:104548. doi: 10.1016/j.phrs.2019.104548. [Epub ahead of print]

PMID:
31759087
2.

Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD.

Karch J, Bround MJ, Khalil H, Sargent MA, Latchman N, Terada N, Peixoto PM, Molkentin JD.

Sci Adv. 2019 Aug 28;5(8):eaaw4597. doi: 10.1126/sciadv.aaw4597. eCollection 2019 Aug.

3.

The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle.

Kwong JQ, Huo J, Bround MJ, Boyer JG, Schwanekamp JA, Ghazal N, Maxwell JT, Jang YC, Khuchua Z, Shi K, Bers DM, Davis J, Molkentin JD.

JCI Insight. 2018 Nov 15;3(22). pii: 121689. doi: 10.1172/jci.insight.121689.

4.

Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase.

Bround MJ, Wambolt R, Cen H, Asghari P, Albu RF, Han J, McAfee D, Pourrier M, Scott NE, Bohunek L, Kulpa JE, Chen SR, Fedida D, Brownsey RW, Borchers CH, Foster LJ, Mayor T, Moore ED, Allard MF, Johnson JD.

J Biol Chem. 2016 Nov 4;291(45):23490-23505. Epub 2016 Sep 12.

5.

Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation.

Szabat M, Page MM, Panzhinskiy E, Skovsø S, Mojibian M, Fernandez-Tajes J, Bruin JE, Bround MJ, Lee JT, Xu EE, Taghizadeh F, O'Dwyer S, van de Bunt M, Moon KM, Sinha S, Han J, Fan Y, Lynn FC, Trucco M, Borchers CH, Foster LJ, Nislow C, Kieffer TJ, Johnson JD.

Cell Metab. 2016 Jan 12;23(1):179-93. doi: 10.1016/j.cmet.2015.10.016. Epub 2015 Nov 25.

6.

Generation and characterization of a mouse model harboring the exon-3 deletion in the cardiac ryanodine receptor.

Liu Y, Wang R, Sun B, Mi T, Zhang J, Mu Y, Chen J, Bround MJ, Johnson JD, Gillis AM, Chen SR.

PLoS One. 2014 Apr 17;9(4):e95615. doi: 10.1371/journal.pone.0095615. eCollection 2014.

7.

Hyperglycemia-induced secretion of endothelial heparanase stimulates a vascular endothelial growth factor autocrine network in cardiomyocytes that promotes recruitment of lipoprotein lipase.

Zhang D, Wan A, Chiu AP, Wang Y, Wang F, Neumaier K, Lal N, Bround MJ, Johnson JD, Vlodavsky I, Rodrigues B.

Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2830-8. doi: 10.1161/ATVBAHA.113.302222. Epub 2013 Oct 10.

PMID:
24115032
8.

Cardiomyocyte ATP production, metabolic flexibility, and survival require calcium flux through cardiac ryanodine receptors in vivo.

Bround MJ, Wambolt R, Luciani DS, Kulpa JE, Rodrigues B, Brownsey RW, Allard MF, Johnson JD.

J Biol Chem. 2013 Jun 28;288(26):18975-86. doi: 10.1074/jbc.M112.427062. Epub 2013 May 15.

9.

Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice.

Bround MJ, Asghari P, Wambolt RB, Bohunek L, Smits C, Philit M, Kieffer TJ, Lakatta EG, Boheler KR, Moore ED, Allard MF, Johnson JD.

Cardiovasc Res. 2012 Dec 1;96(3):372-80. doi: 10.1093/cvr/cvs260. Epub 2012 Aug 6.

10.

Nanospaces between endoplasmic reticulum and mitochondria as control centres of pancreatic β-cell metabolism and survival.

Johnson JD, Bround MJ, White SA, Luciani DS.

Protoplasma. 2012 Feb;249 Suppl 1:S49-58. doi: 10.1007/s00709-011-0349-3. Epub 2011 Nov 22. Review.

PMID:
22105567

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