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Items: 29

1.

The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth.

Chaaban S, Jariwala S, Hsu CT, Redemann S, Kollman JM, Müller-Reichert T, Sept D, Bui KH, Brouhard GJ.

Dev Cell. 2018 Oct 22;47(2):191-204.e8. doi: 10.1016/j.devcel.2018.08.023. Epub 2018 Sep 20.

PMID:
30245157
2.

Microtubule dynamics: an interplay of biochemistry and mechanics.

Brouhard GJ, Rice LM.

Nat Rev Mol Cell Biol. 2018 Jul;19(7):451-463. doi: 10.1038/s41580-018-0009-y. Review.

3.

A microtubule bestiary: structural diversity in tubulin polymers.

Chaaban S, Brouhard GJ.

Mol Biol Cell. 2017 Nov 1;28(22):2924-2931. doi: 10.1091/mbc.E16-05-0271. Review.

4.

GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK.

Bendre S, Rondelet A, Hall C, Schmidt N, Lin YC, Brouhard GJ, Bird AW.

J Cell Biol. 2016 Dec 5;215(5):631-647. Epub 2016 Nov 23.

5.

The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.

Wieczorek M, Tcherkezian J, Bernier C, Prota AE, Chaaban S, Rolland Y, Godbout C, Hancock MA, Arezzo JC, Ocal O, Rocha C, Olieric N, Hall A, Ding H, Bramoullé A, Annis MG, Zogopoulos G, Harran PG, Wilkie TM, Brekken RA, Siegel PM, Steinmetz MO, Shore GC, Brouhard GJ, Roulston A.

Sci Transl Med. 2016 Nov 16;8(365):365ra159. Erratum in: Sci Transl Med. 2017 Dec 20;9(421):.

6.

Loss of function of the Drosophila Ninein-related centrosomal protein Bsg25D causes mitotic defects and impairs embryonic development.

Kowanda M, Bergalet J, Wieczorek M, Brouhard G, Lécuyer É, Lasko P.

Biol Open. 2016 Aug 15;5(8):1040-51. doi: 10.1242/bio.019638.

7.

Microtubule-associated proteins control the kinetics of microtubule nucleation.

Wieczorek M, Bechstedt S, Chaaban S, Brouhard GJ.

Nat Cell Biol. 2015 Jul;17(7):907-16. doi: 10.1038/ncb3188. Epub 2015 Jun 22.

PMID:
26098575
8.

Dynamic instability 30 years later: complexities in microtubule growth and catastrophe.

Brouhard GJ.

Mol Biol Cell. 2015 Apr 1;26(7):1207-10. doi: 10.1091/mbc.E13-10-0594. Review.

9.

The contribution of αβ-tubulin curvature to microtubule dynamics.

Brouhard GJ, Rice LM.

J Cell Biol. 2014 Nov 10;207(3):323-34. doi: 10.1083/jcb.201407095. Review.

10.

Doublecortin recognizes the longitudinal curvature of the microtubule end and lattice.

Bechstedt S, Lu K, Brouhard GJ.

Curr Biol. 2014 Oct 20;24(20):2366-75. doi: 10.1016/j.cub.2014.08.039. Epub 2014 Oct 2.

11.

Collapsin response mediator protein 4 regulates growth cone dynamics through the actin and microtubule cytoskeleton.

Khazaei MR, Girouard MP, Alchini R, Ong Tone S, Shimada T, Bechstedt S, Cowan M, Guillet D, Wiseman PW, Brouhard G, Cloutier JF, Fournier AE.

J Biol Chem. 2014 Oct 24;289(43):30133-43. doi: 10.1074/jbc.M114.570440. Epub 2014 Sep 15.

12.

Microtubules accelerate the kinase activity of Aurora-B by a reduction in dimensionality.

Noujaim M, Bechstedt S, Wieczorek M, Brouhard GJ.

PLoS One. 2014 Feb 3;9(2):e86786. doi: 10.1371/journal.pone.0086786. eCollection 2014.

13.

Fluorescence-based assays for microtubule architecture.

Bechstedt S, Brouhard GJ.

Methods Cell Biol. 2013;115:343-54. doi: 10.1016/B978-0-12-407757-7.00021-9.

PMID:
23973082
14.

Measuring ligand-receptor binding kinetics and dynamics using k-space image correlation spectroscopy.

Brandão HB, Sangji H, Pandžić E, Bechstedt S, Brouhard GJ, Wiseman PW.

Methods. 2014 Mar 15;66(2):273-82. doi: 10.1016/j.ymeth.2013.07.042. Epub 2013 Aug 9.

PMID:
23938869
15.

Motors and MAPs collaborate to size up microtubules.

Bechstedt S, Brouhard GJ.

Dev Cell. 2013 Jul 29;26(2):118-20. doi: 10.1016/j.devcel.2013.07.010.

16.

Polymicrogyria with dysmorphic basal ganglia? Think tubulin!

Amrom D, Tanyalçin I, Verhelst H, Deconinck N, Brouhard GJ, Décarie JC, Vanderhasselt T, Das S, Hamdan FF, Lissens W, Michaud JL, Jansen AC.

Clin Genet. 2014 Feb;85(2):178-83. doi: 10.1111/cge.12141. Epub 2013 Apr 24.

PMID:
23495813
17.

Microtubules: sizing up the GTP cap.

Brouhard G, Sept D.

Curr Biol. 2012 Sep 25;22(18):R802-3. doi: 10.1016/j.cub.2012.07.050.

18.

Doublecortin recognizes the 13-protofilament microtubule cooperatively and tracks microtubule ends.

Bechstedt S, Brouhard GJ.

Dev Cell. 2012 Jul 17;23(1):181-92. doi: 10.1016/j.devcel.2012.05.006. Epub 2012 Jun 21.

19.

Variations on the single-molecule assay for microtubule-associated proteins and kinesins.

Bechstedt S, Wieczorek M, Noujaim M, Brouhard GJ.

Methods Mol Biol. 2011;777:167-76. doi: 10.1007/978-1-61779-252-6_12.

PMID:
21773928
20.

XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region.

Widlund PO, Stear JH, Pozniakovsky A, Zanic M, Reber S, Brouhard GJ, Hyman AA, Howard J.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2741-6. doi: 10.1073/pnas.1016498108. Epub 2011 Jan 31.

21.

Quality control in single-molecule studies of kinesins and microtubule-associated proteins.

Brouhard GJ.

Methods Cell Biol. 2010;97:497-506. doi: 10.1016/S0091-679X(10)97026-X. Review.

PMID:
20719287
22.

CLASP promotes microtubule rescue by recruiting tubulin dimers to the microtubule.

Al-Bassam J, Kim H, Brouhard G, van Oijen A, Harrison SC, Chang F.

Dev Cell. 2010 Aug 17;19(2):245-58. doi: 10.1016/j.devcel.2010.07.016.

23.

Motor proteins: kinesins influence each other through load.

Brouhard GJ.

Curr Biol. 2010 May 25;20(10):R448-50. doi: 10.1016/j.cub.2010.03.034.

24.

Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy.

Gell C, Bormuth V, Brouhard GJ, Cohen DN, Diez S, Friel CT, Helenius J, Nitzsche B, Petzold H, Ribbe J, Schäffer E, Stear JH, Trushko A, Varga V, Widlund PO, Zanic M, Howard J.

Methods Cell Biol. 2010;95:221-45. doi: 10.1016/S0091-679X(10)95013-9. Review.

PMID:
20466138
25.

Dynamics of zebrafish somitogenesis.

Schröter C, Herrgen L, Cardona A, Brouhard GJ, Feldman B, Oates AC.

Dev Dyn. 2008 Mar;237(3):545-53. doi: 10.1002/dvdy.21458.

26.

XMAP215 is a processive microtubule polymerase.

Brouhard GJ, Stear JH, Noetzel TL, Al-Bassam J, Kinoshita K, Harrison SC, Howard J, Hyman AA.

Cell. 2008 Jan 11;132(1):79-88. doi: 10.1016/j.cell.2007.11.043.

27.

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends.

Helenius J, Brouhard G, Kalaidzidis Y, Diez S, Howard J.

Nature. 2006 May 4;441(7089):115-9.

PMID:
16672973
28.

Microtubule movements on the arms of mitotic chromosomes: polar ejection forces quantified in vitro.

Brouhard GJ, Hunt AJ.

Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13903-8. Epub 2005 Sep 20.

29.

Advanced optical tweezers for the study of cellular and molecular biomechanics.

Brouhard GJ, Schek HT 3rd, Hunt AJ.

IEEE Trans Biomed Eng. 2003 Jan;50(1):121-5.

PMID:
12617534

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