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Items: 1 to 50 of 210

1.

Terminally Differentiated Effector Memory CD8+ T Cells Identify Kidney Transplant Recipients at High Risk of Graft Failure.

Jacquemont L, Tilly G, Yap M, Doan-Ngoc TM, Danger R, Guérif P, Delbos F, Martinet B, Giral M, Foucher Y, Brouard S, Degauque N.

J Am Soc Nephrol. 2020 Mar 12. pii: ASN.2019080847. doi: 10.1681/ASN.2019080847. [Epub ahead of print]

PMID:
32165419
2.

Neutrophils cause a "NET" increase in skin allograft allogenicity.

Brouard S, Mooney N.

Am J Transplant. 2020 Apr;20(4):922-923. doi: 10.1111/ajt.15746. Epub 2020 Jan 7. No abstract available.

PMID:
31846552
3.

The EKiTE network (epidemiology in kidney transplantation - a European validated database): an initiative epidemiological and translational European collaborative research.

Lorent M, Foucher Y, Kerleau K, Brouard S, Baayen C, Lebouter S, Naesens M, Bestard Matamoros O, Åsberg A, Giral M; EKiTE consortium.

BMC Nephrol. 2019 Oct 11;20(1):365. doi: 10.1186/s12882-019-1522-8.

4.

CXCR5+PD1+ICOS+ Circulating T Follicular Helpers Are Associated With de novo Donor-Specific Antibodies After Renal Transplantation.

Danger R, Chesneau M, Delbos F, Le Bot S, Kerleau C, Chenouard A, Ville S, Degauque N, Conchon S, Cesbron A, Giral M, Brouard S.

Front Immunol. 2019 Sep 10;10:2071. doi: 10.3389/fimmu.2019.02071. eCollection 2019.

5.

Early Identification of Chronic Lung Allograft Dysfunction: The Need of Biomarkers.

Tissot A, Danger R, Claustre J, Magnan A, Brouard S.

Front Immunol. 2019 Jul 17;10:1681. doi: 10.3389/fimmu.2019.01681. eCollection 2019. Review.

6.

Unique and specific Proteobacteria diversity in urinary microbiota of tolerant kidney transplanted recipients.

Colas L, Mongodin EF, Montassier E, Chesneau M, Guerif P, Hittle L, Giral M, Bromberg JS, Brouard S; DIVAT Consortium.

Am J Transplant. 2020 Jan;20(1):145-158. doi: 10.1111/ajt.15549. Epub 2019 Sep 9.

PMID:
31374143
7.

Interleukin-7 receptor blockade by an anti-CD127 monoclonal antibody in nonhuman primate kidney transplantation.

Mai HL, Nguyen TVH, Branchereau J, Poirier N, Renaudin K, Mary C, Belarif L, Minault D, Hervouet J, Le Bas-Berdardet S, Soulillou JP, Vanhove B, Blancho G, Brouard S.

Am J Transplant. 2020 Jan;20(1):101-111. doi: 10.1111/ajt.15543. Epub 2019 Aug 14.

PMID:
31344323
8.

Blood CD9+ B cell, a biomarker of bronchiolitis obliterans syndrome after lung transplantation.

Brosseau C, Danger R, Durand M, Durand E, Foureau A, Lacoste P, Tissot A, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Claustre J, Magnan A, Brouard S; COLT and SysCLAD Consortia.

Am J Transplant. 2019 Nov;19(11):3162-3175. doi: 10.1111/ajt.15532. Epub 2019 Aug 21.

PMID:
31305014
9.

Elicited and pre-existing anti-Neu5Gc antibodies differentially affect human endothelial cells transcriptome.

Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Arye S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP.

Xenotransplantation. 2019 Nov;26(6):e12535. doi: 10.1111/xen.12535. Epub 2019 Jul 10.

PMID:
31293002
10.

Role of JAK inhibitors and immune cells in transplantation.

Sailliet N, Brosseau C, Robert JM, Brouard S.

Cytokine Growth Factor Rev. 2019 Jun;47:62-73. doi: 10.1016/j.cytogfr.2019.05.002. Epub 2019 May 11. Review.

PMID:
31133508
11.

BOB.1 controls memory B-cell fate in the germinal center reaction.

Levels MJ, Fehres CM, van Baarsen LGM, van Uden NOP, Germar K, O'Toole TG, Blijdorp ICJ, Semmelink JF, Doorenspleet ME, Bakker AQ, Krasavin M, Tomilin A, Brouard S, Spits H, Baeten DLP, Yeremenko NG.

J Autoimmun. 2019 Jul;101:131-144. doi: 10.1016/j.jaut.2019.04.011. Epub 2019 Apr 30.

12.

Highly Variable Sialylation Status of Donor-Specific Antibodies Does Not Impact Humoral Rejection Outcomes.

Barba T, Harb J, Ducreux S, Koenig A, Mathias V, Rabeyrin M, Pouliquen E, Sicard A, Chartoire D, Dugast E, Defrance T, Morelon E, Brouard S, Dubois V, Thaunat O.

Front Immunol. 2019 Mar 20;10:513. doi: 10.3389/fimmu.2019.00513. eCollection 2019.

13.

IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease.

Belarif L, Danger R, Kermarrec L, Nerrière-Daguin V, Pengam S, Durand T, Mary C, Kerdreux E, Gauttier V, Kucik A, Thepenier V, Martin JC, Chang C, Rahman A, Guen NS, Braudeau C, Abidi A, David G, Malard F, Takoudju C, Martinet B, Gérard N, Neveu I, Neunlist M, Coron E, MacDonald TT, Desreumaux P, Mai HL, Le Bas-Bernardet S, Mosnier JF, Merad M, Josien R, Brouard S, Soulillou JP, Blancho G, Bourreille A, Naveilhan P, Vanhove B, Poirier N.

J Clin Invest. 2019 Apr 2;129(5):1910-1925. doi: 10.1172/JCI121668. eCollection 2019 Apr 2.

14.

CD9+ Regulatory B Cells Induce T Cell Apoptosis via IL-10 and Are Reduced in Severe Asthmatic Patients.

Brosseau C, Durand M, Colas L, Durand E, Foureau A, Cheminant MA, Bouchaud G, Castan L, Klein M, Magnan A, Brouard S.

Front Immunol. 2018 Dec 21;9:3034. doi: 10.3389/fimmu.2018.03034. eCollection 2018.

15.

Dampening of CD8+ T Cell Response by B Cell Depletion Therapy in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Néel A, Bucchia M, Néel M, Tilly G, Caristan A, Yap M, Rimbert M, Bruneau S, Cadoux M, Agard C, Hourmant M, Godmer P, Brouard S, Bressollette C, Hamidou M, Josien R, Fakhouri F, Degauque N.

Arthritis Rheumatol. 2019 Apr;71(4):641-650. doi: 10.1002/art.40766. Epub 2019 Mar 8.

16.

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates.

Belarif L, Mary C, Jacquemont L, Mai HL, Danger R, Hervouet J, Minault D, Thepenier V, Nerrière-Daguin V, Nguyen E, Pengam S, Largy E, Delobel A, Martinet B, Le Bas-Bernardet S, Brouard S, Soulillou JP, Degauque N, Blancho G, Vanhove B, Poirier N.

Nat Commun. 2018 Oct 26;9(1):4483. doi: 10.1038/s41467-018-06804-y.

17.

CD9 Tetraspanin: A New Pathway for the Regulation of Inflammation?

Brosseau C, Colas L, Magnan A, Brouard S.

Front Immunol. 2018 Oct 9;9:2316. doi: 10.3389/fimmu.2018.02316. eCollection 2018. Review.

18.

[COLT: Ten years of research in lung transplantation, results and perspectives].

Tissot A, Foureau A, Brosseau C, Danger R, Roux A, Bernasconi E, Gomez C, Durand M, Picard BR, Le Pavec J, Claustre J, Lacoste P, Benmerad M, Pain M, Siroux V, Royer PJ, Mordant P, Reynaud-Gaubert M, Kessler R, Brugière O, Mornex JF, Dromer C, Dahan M, Knoop C, Boussaud V, Koutsokera A, Botturi-Cavaillès K, Durand E, Loy J, Nicod L, Pison C, Brouard S, Blanc FX, Magnan A; consortium COLT.

Rev Mal Respir. 2018 Sep;35(7):699-705. doi: 10.1016/j.rmr.2018.06.007. Epub 2018 Aug 9. French. No abstract available.

PMID:
30100530
19.

Immune Alterations in Patients With Type 1 Autoimmune Hepatitis Persist Upon Standard Immunosuppressive Treatment.

Renand A, Habes S, Mosnier JF, Aublé H, Judor JP, Vince N, Hulin P, Nedellec S, Métairie S, Archambeaud I, Brouard S, Gournay J, Conchon S.

Hepatol Commun. 2018 Aug 6;2(8):968-981. doi: 10.1002/hep4.1202. eCollection 2018 Aug.

20.

Molecular Pathways Underlying Adaptive Repair of the Injured Kidney: Novel Donation After Cardiac Death and Acute Kidney Injury Platforms.

Orlando G, Danger R, Okut H, Edgar L, Bussolati B, Gall E, Bergman CR, Tamburrini R, Gazia C, Farney AC, Freedman BI, McPherson G, Rogers J, Stratta RJ, Brouard S, Walker SJ.

Ann Surg. 2020 Feb;271(2):383-390. doi: 10.1097/SLA.0000000000002946.

21.

Regulation of the Immune Response by the Inflammatory Metabolic Microenvironment in the Context of Allotransplantation.

Degauque N, Brosseau C, Brouard S.

Front Immunol. 2018 Jun 25;9:1465. doi: 10.3389/fimmu.2018.01465. eCollection 2018. Review.

22.

The 1-year Renal Biopsy Index: a scoring system to drive biopsy indication at 1-year post-kidney transplantation.

Giral M, Renaudin K, Naesens M, Luning R, Anglicheau D, Morelon E, Huneau A, Paul C, Brouard S, Couvrat-Desvergnes G, Foucher Y, Dantan E.

Transpl Int. 2018 Jun 12. doi: 10.1111/tri.13290. [Epub ahead of print] Review.

23.

Poor Patient and Graft Outcome After Induction Treatment by Antithymocyte Globulin in Recipients of a Kidney Graft After Nonrenal Organ Transplantation.

Mai HL, Treilhaud M, Ben-Arye SL, Yu H, Perreault H, Ang E, Trébern-Launay K, Laurent J, Malard-Castagnet S, Cesbron A, Nguyen TVH, Brouard S, Rostaing L, Houssel-Debry P, Legendre C, Girerd S, Kessler M, Morelon E, Sicard A, Garrigue V, Karam G, Chen X, Giral M, Padler-Karavani V, Soulillou JP.

Transplant Direct. 2018 Mar 20;4(4):e357. doi: 10.1097/TXD.0000000000000772. eCollection 2018 Apr.

24.

Correction: Bone marrow cell extract promotes the regeneration of irradiated bone.

Michel G, Blery P, Henoux M, Guicheux J, Weiss P, Dugast E, Brouard S, Malard O, Espitalier F.

PLoS One. 2018 Apr 17;13(4):e0196145. doi: 10.1371/journal.pone.0196145. eCollection 2018.

25.

Corrigendum: Broad Impairment of Natural Killer Cells From Operationally Tolerant Kidney Transplanted Patients.

Dugast E, David G, Oger R, Danger R, Judor JP, Gagne K, Chesneau M, Degauque N, Soulillou JP, Paul P, Picard C, Guerif P, Conchon S, Giral M, Gervois N, Retière C, Brouard S.

Front Immunol. 2018 Mar 26;9:589. doi: 10.3389/fimmu.2018.00589. eCollection 2018.

26.

High circulating CD4+CD25hiFOXP3+ T-cell sub-population early after lung transplantation is associated with development of bronchiolitis obliterans syndrome.

Durand M, Lacoste P, Danger R, Jacquemont L, Brosseau C, Durand E, Tilly G, Loy J, Foureau A, Royer PJ, Tissot A, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Claustre J, Degauque N, Magnan A, Brouard S; COLT and SysCLAD Consortia.

J Heart Lung Transplant. 2018 Jun;37(6):770-781. doi: 10.1016/j.healun.2018.01.1306. Epub 2018 Mar 20.

PMID:
29571601
27.

B cells in operational tolerance.

Chesneau M, Danger R, Soulillou JP, Brouard S.

Hum Immunol. 2018 May;79(5):373-379. doi: 10.1016/j.humimm.2018.02.009. Epub 2018 Feb 16. Review.

PMID:
29458071
28.

Increased degradation of ATP is driven by memory regulatory T cells in kidney transplantation tolerance.

Durand M, Dubois F, Dejou C, Durand E, Danger R, Chesneau M, Brosseau C, Guerif P, Soulillou JP, Degauque N, Eliaou JF, Giral M, Bonnefoy N, Brouard S.

Kidney Int. 2018 May;93(5):1154-1164. doi: 10.1016/j.kint.2017.12.004. Epub 2018 Feb 15.

PMID:
29455908
29.

Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome.

Danger R, Royer PJ, Reboulleau D, Durand E, Loy J, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Gomez C, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Foureau A, Pison C, Koutsokera A, Nicod LP, Brouard S, Magnan A; COLT and SysCLAD Consortia.

Front Immunol. 2018 Jan 11;8:1841. doi: 10.3389/fimmu.2017.01841. eCollection 2017.

30.

Food allergen-sensitized CCR9+ lymphocytes enhance airways allergic inflammation in mice.

Castan L, Cheminant MA, Colas L, Brouard S, Magnan A, Bouchaud G.

Allergy. 2018 Jul;73(7):1505-1514. doi: 10.1111/all.13386. Epub 2018 Feb 20.

PMID:
29315632
31.

Broad Impairment of Natural Killer Cells from Operationally Tolerant Kidney Transplanted Patients.

Dugast E, David G, Oger R, Danger R, Judor JP, Gagne K, Chesneau M, Degauque N, Soulillou JP, Paul P, Picard C, Guerif P, Conchon S, Giral M, Gervois N, Retière C, Brouard S.

Front Immunol. 2017 Dec 11;8:1721. doi: 10.3389/fimmu.2017.01721. eCollection 2017. Erratum in: Front Immunol. 2018 Mar 26;9:589.

32.

TLR3 promotes MMP-9 production in primary human airway epithelial cells through Wnt/β-catenin signaling.

Royer PJ, Henrio K, Pain M, Loy J, Roux A, Tissot A, Lacoste P, Pison C, Brouard S, Magnan A; COLT consortium.

Respir Res. 2017 Dec 13;18(1):208. doi: 10.1186/s12931-017-0690-y.

33.

Pro-inflammatory State in Monoclonal Gammopathy of Undetermined Significance and in Multiple Myeloma Is Characterized by Low Sialylation of Pathogen-Specific and Other Monoclonal Immunoglobulins.

Bosseboeuf A, Allain-Maillet S, Mennesson N, Tallet A, Rossi C, Garderet L, Caillot D, Moreau P, Piver E, Girodon F, Perreault H, Brouard S, Nicot A, Bigot-Corbel E, Hermouet S, Harb J.

Front Immunol. 2017 Oct 19;8:1347. doi: 10.3389/fimmu.2017.01347. eCollection 2017.

34.

An intermediate level of CD161 expression defines a novel activated, inflammatory, and pathogenic subset of CD8+ T cells involved in multiple sclerosis.

Nicol B, Salou M, Vogel I, Garcia A, Dugast E, Morille J, Kilens S, Charpentier E, Donnart A, Nedellec S, Jacq-Foucher M, Le Frère F, Wiertlewski S, Bourreille A, Brouard S, Michel L, David L, Gourraud PA, Degauque N, Nicot AB, Berthelot L, Laplaud DA.

J Autoimmun. 2018 Mar;88:61-74. doi: 10.1016/j.jaut.2017.10.005. Epub 2017 Oct 18.

35.

IL-15 Harnesses Pro-inflammatory Function of TEMRA CD8 in Kidney-Transplant Recipients.

Tilly G, Doan-Ngoc TM, Yap M, Caristan A, Jacquemont L, Danger R, Cadoux M, Bruneau S, Giral M, Guerif P, Nicol B, Garcia A, Laplaud DA, Brouard S, Pecqueur Hellman C, Degauque N.

Front Immunol. 2017 Jun 30;8:778. doi: 10.3389/fimmu.2017.00778. eCollection 2017.

36.

Bone marrow cell extract promotes the regeneration of irradiated bone.

Michel G, Blery P, Henoux M, Guicheux J, Weiss P, Dugast E, Brouard S, Malard O, Espitalier F.

PLoS One. 2017 May 18;12(5):e0178060. doi: 10.1371/journal.pone.0178060. eCollection 2017. Erratum in: PLoS One. 2018 Apr 17;13(4):e0196145.

37.

Decrease of blood anti-α1,3 Galactose Abs levels in multiple sclerosis (MS) and clinically isolated syndrome (CIS) patients.

Le Berre L, Rousse J, Gourraud PA, Imbert-Marcille BM, Salama A, Evanno G, Semana G, Nicot A, Dugast E, Guérif P, Adjaoud C, Freour T, Brouard S, Agbalika F, Marignier R, Brassat D, Laplaud DA, Drouet E, Van Pesch V, Soulillou JP.

Clin Immunol. 2017 Jul;180:128-135. doi: 10.1016/j.clim.2017.05.006. Epub 2017 May 18.

38.

A composite score associated with spontaneous operational tolerance in kidney transplant recipients.

Danger R, Chesneau M, Paul C, Guérif P, Durand M, Newell KA, Kanaparthi S, Turka LA, Soulillou JP, Houlgatte R, Giral M, Ramstein G, Brouard S.

Kidney Int. 2017 Jun;91(6):1473-1481. doi: 10.1016/j.kint.2016.12.020. Epub 2017 Feb 24.

39.

Anti-Gal and Anti-Neu5Gc Responses in Nonimmunosuppressed Patients After Treatment With Rabbit Antithymocyte Polyclonal IgGs.

Salama A, Evanno G, Lim N, Rousse J, Le Berre L, Nicot A, Bach JM, Brouard S, Harris KM, Ehlers MR, Gitelman SE, Soulillou JP.

Transplantation. 2017 Oct;101(10):2501-2507. doi: 10.1097/TP.0000000000001686.

PMID:
28198767
40.

Synthetic Fusion Protein CAR Technology to Redirect T Cell Antigen Specificity to Promote Organ Transplant Tolerance.

Brouard S, Mooney N.

Am J Transplant. 2017 Apr;17(4):854-855. doi: 10.1111/ajt.14211. Epub 2017 Mar 4. No abstract available.

41.

Neu5Gc and α1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs.

Salama A, Mosser M, Lévêque X, Perota A, Judor JP, Danna C, Pogu S, Mouré A, Jégou D, Gaide N, Abadie J, Gauthier O, Concordet JP, Le Bas-Bernardet S, Riochet D, Le Berre L, Hervouet J, Minault D, Weiss P, Guicheux J, Brouard S, Bosch S, Lagutina I, Duchi R, Lazzari G, Cozzi E, Blancho G, Conchon S, Galli C, Soulillou JP, Bach JM.

Diabetes. 2017 Apr;66(4):987-993. doi: 10.2337/db16-1060. Epub 2017 Jan 12.

42.

T Cells Promote Bronchial Epithelial Cell Secretion of Matrix Metalloproteinase-9 via a C-C Chemokine Receptor Type 2 Pathway: Implications for Chronic Lung Allograft Dysfunction.

Pain M, Royer PJ, Loy J, Girardeau A, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Pison C, Danger R, Brouard S, Magnan A; COLT Consortium.

Am J Transplant. 2017 Jun;17(6):1502-1514. doi: 10.1111/ajt.14166. Epub 2017 Jan 23.

43.

Alloantigen gene transfer to hepatocytes promotes tolerance to pancreatic islet graft by inducing CD8+ regulatory T cells.

Le Guen V, Judor JP, Boeffard F, Gauttier V, Ferry N, Soulillou JP, Brouard S, Conchon S.

J Hepatol. 2017 Apr;66(4):765-777. doi: 10.1016/j.jhep.2016.11.019. Epub 2016 Nov 30.

PMID:
27914923
44.

Renal Operational Tolerance Is Associated With a Defect of Blood Tfh Cells That Exhibit Impaired B Cell Help.

Chenouard A, Chesneau M, Bui Nguyen L, Le Bot S, Cadoux M, Dugast E, Paul C, Malard-Castagnet S, Ville S, Guérif P, Soulillou JP, Degauque N, Danger R, Giral M, Brouard S.

Am J Transplant. 2017 Jun;17(6):1490-1501. doi: 10.1111/ajt.14142. Epub 2017 Jan 19.

45.

Immune monitoring in renal transplantation: The search for biomarkers.

Danger R, Sawitzki B, Brouard S.

Eur J Immunol. 2016 Dec;46(12):2695-2704. doi: 10.1002/eji.201545963. Review.

46.

Failure of Calcineurin Inhibitor (Tacrolimus) Weaning Randomized Trial in Long-Term Stable Kidney Transplant Recipients.

Dugast E, Soulillou JP, Foucher Y, Papuchon E, Guerif P, Paul C, Riochet D, Chesneau M, Cesbron A, Renaudin K, Dantal J, Giral M, Brouard S.

Am J Transplant. 2016 Nov;16(11):3255-3261. doi: 10.1111/ajt.13946. Epub 2016 Jul 29.

47.

Neuropathologic, phenotypic and functional analyses of Mucosal Associated Invariant T cells in Multiple Sclerosis.

Salou M, Nicol B, Garcia A, Baron D, Michel L, Elong-Ngono A, Hulin P, Nedellec S, Jacq-Foucher M, Le Frère F, Jousset N, Bourreille A, Wiertlewski S, Soulillou JP, Brouard S, Nicot AB, Degauque N, Laplaud DA.

Clin Immunol. 2016 May;166-167:1-11. doi: 10.1016/j.clim.2016.03.014. Epub 2016 Apr 2.

PMID:
27050759
48.

Cross-Reactivity of TCR Repertoire: Current Concepts, Challenges, and Implication for Allotransplantation.

Degauque N, Brouard S, Soulillou JP.

Front Immunol. 2016 Mar 24;7:89. doi: 10.3389/fimmu.2016.00089. eCollection 2016. Review.

49.

The Leuven Immunomodulatory Protocol Promotes T-Regulatory Cells and Substantially Prolongs Survival After First Intestinal Transplantation.

Ceulemans LJ, Braza F, Monbaliu D, Jochmans I, De Hertogh G, Du Plessis J, Emonds MP, Kitade H, Kawai M, Li Y, Zhao X, Koshiba T, Sprangers B, Brouard S, Waer M, Pirenne J.

Am J Transplant. 2016 Oct;16(10):2973-2985. doi: 10.1111/ajt.13815. Epub 2016 May 12.

50.

Role of TLRs and DAMPs in allograft inflammation and transplant outcomes.

Braza F, Brouard S, Chadban S, Goldstein DR.

Nat Rev Nephrol. 2016 May;12(5):281-90. doi: 10.1038/nrneph.2016.41. Epub 2016 Mar 30. Review.

PMID:
27026348

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