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Items: 1 to 50 of 62


A cross-sectional pilot study of birth mode and vaginal microbiota in reproductive-age women.

Stennett CA, Dyer TV, He X, Robinson CK, Ravel J, Ghanem KG, Brotman RM.

PLoS One. 2020 Apr 1;15(4):e0228574. doi: 10.1371/journal.pone.0228574. eCollection 2020.


Asymptomatic Bacterial Vaginosis Is Associated With Depletion of Mature Superficial Cells Shed From the Vaginal Epithelium.

O'Hanlon DE, Gajer P, Brotman RM, Ravel J.

Front Cell Infect Microbiol. 2020 Mar 10;10:106. doi: 10.3389/fcimb.2020.00106. eCollection 2020.


Authors' reply re: The vaginal metabolome and microbiota of cervical HPV-positive and HPV-negative women: a cross-sectional analysis.

Borgogna JC, Shardell MD, Santori EK, Nelson TM, Rath JM, Glover ED, Ravel J, Gravitt P, Yeoman CJ, Brotman RM.

BJOG. 2020 Mar 10. doi: 10.1111/1471-0528.16148. [Epub ahead of print] No abstract available.


Bacterial vaginosis diagnosis and treatment in postmenopausal women: a survey of clinician practices.

Mark KS, Tenorio B, Stennett CA, Ghanem KG, Brotman RM.

Menopause. 2020 Mar 2. doi: 10.1097/GME.0000000000001515. [Epub ahead of print]


A comprehensive non-redundant gene catalog reveals extensive within-community intraspecies diversity in the human vagina.

Ma B, France MT, Crabtree J, Holm JB, Humphrys MS, Brotman RM, Ravel J.

Nat Commun. 2020 Feb 26;11(1):940. doi: 10.1038/s41467-020-14677-3.


The association of Chlamydia trachomatis and Mycoplasma genitalium infection with the vaginal metabolome.

Borgogna JC, Shardell MD, Yeoman CJ, Ghanem KG, Kadriu H, Ulanov AV, Gaydos CA, Hardick J, Robinson CK, Bavoil PM, Ravel J, Brotman RM, Tuddenham S.

Sci Rep. 2020 Feb 25;10(1):3420. doi: 10.1038/s41598-020-60179-z.


Dietary macronutrient intake and molecular-bacterial vaginosis: Role of fiber.

Shivakoti R, Tuddenham S, Caulfield LE, Murphy C, Robinson C, Ravel J, Ghanem KG, Brotman RM.

Clin Nutr. 2020 Jan 29. pii: S0261-5614(20)30031-5. doi: 10.1016/j.clnu.2020.01.011. [Epub ahead of print]


The vaginal metabolome and microbiota of cervical HPV-positive and HPV-negative women: a cross-sectional analysis.

Borgogna JC, Shardell MD, Santori EK, Nelson TM, Rath JM, Glover ED, Ravel J, Gravitt PE, Yeoman CJ, Brotman RM.

BJOG. 2020 Jan;127(2):182-192. doi: 10.1111/1471-0528.15981. Epub 2019 Nov 20.


Clinicians' Use of Intravaginal Boric Acid Maintenance Therapy for Recurrent Vulvovaginal Candidiasis and Bacterial Vaginosis.

Powell A, Ghanem KG, Rogers L, Zinalabedini A, Brotman RM, Zenilman J, Tuddenham S.

Sex Transm Dis. 2019 Dec;46(12):810-812. doi: 10.1097/OLQ.0000000000001063.


Chlamydia in adolescent/adult reproductive management trial study (CHARM): Clinical core protocol.

Mark KS, Brotman RM, Martinez-Greiwe S, Terplan M, Bavoil P, Ravel J.

Contemp Clin Trials Commun. 2019 Jul 19;16:100414. doi: 10.1016/j.conctc.2019.100414. eCollection 2019 Dec.


Associations between dietary micronutrient intake and molecular-Bacterial Vaginosis.

Tuddenham S, Ghanem KG, Caulfield LE, Rovner AJ, Robinson C, Shivakoti R, Miller R, Burke A, Murphy C, Ravel J, Brotman RM.

Reprod Health. 2019 Oct 22;16(1):151. doi: 10.1186/s12978-019-0814-6.


Risk and protective factors associated with BV chronicity among women in Rakai, Uganda.

Thoma ME, Brotman RM, Gray RH, Sewankambo NK, Wawer MJ.

Sex Transm Infect. 2019 Oct 10. pii: sextrans-2019-054145. doi: 10.1136/sextrans-2019-054145. [Epub ahead of print]


Nonoptimal Vaginal Microbiota After Azithromycin Treatment for Chlamydia trachomatis Infection.

Tamarelle J, Ma B, Gajer P, Humphrys MS, Terplan M, Mark KS, Thiébaut ACM, Forney LJ, Brotman RM, Delarocque-Astagneau E, Bavoil PM, Ravel J.

J Infect Dis. 2020 Feb 3;221(4):627-635. doi: 10.1093/infdis/jiz499.


Personal and Clinical Vaginal Lubricants: Impact on Local Vaginal Microenvironment and Implications for Epithelial Cell Host Response and Barrier Function.

Wilkinson EM, Łaniewski P, Herbst-Kralovetz MM, Brotman RM.

J Infect Dis. 2019 Nov 6;220(12):2009-2018. doi: 10.1093/infdis/jiz412.


The Vaginal Microbiota and Behavioral Factors Associated With Genital Candida albicans Detection in Reproductive-Age Women.

Brown SE, Schwartz JA, Robinson CK, OʼHanlon DE, Bradford LL, He X, Mark KS, Bruno VM, Ravel J, Brotman RM.

Sex Transm Dis. 2019 Nov;46(11):753-758. doi: 10.1097/OLQ.0000000000001066.


The Cervicovaginal Microbiota-Host Interaction Modulates Chlamydia trachomatis Infection.

Edwards VL, Smith SB, McComb EJ, Tamarelle J, Ma B, Humphrys MS, Gajer P, Gwilliam K, Schaefer AM, Lai SK, Terplan M, Mark KS, Brotman RM, Forney LJ, Bavoil PM, Ravel J.

mBio. 2019 Aug 13;10(4). pii: e01548-19. doi: 10.1128/mBio.01548-19.


Patterns in On-time, Daily Submission of a Short Web-Based Personal Behavior Survey in a Longitudinal Women's Health Study.

Crowder HR, Brown SE, Stennett CA, Johnston E, Wnorowski AM, Mark KS, Brotman RM.

Sex Transm Dis. 2019 Aug;46(8):e80-e82. doi: 10.1097/OLQ.0000000000001001.


Ultrahigh-Throughput Multiplexing and Sequencing of >500-Base-Pair Amplicon Regions on the Illumina HiSeq 2500 Platform.

Holm JB, Humphrys MS, Robinson CK, Settles ML, Ott S, Fu L, Yang H, Gajer P, He X, McComb E, Gravitt PE, Ghanem KG, Brotman RM, Ravel J.

mSystems. 2019 Feb 19;4(1). pii: e00029-19. doi: 10.1128/mSystems.00029-19. eCollection 2019 Jan-Feb.


Perceived stress and incident sexually transmitted infections in a prospective cohort.

Turpin R, Brotman RM, Miller RS, Klebanoff MA, He X, Slopen N.

Ann Epidemiol. 2019 Apr;32:20-27. doi: 10.1016/j.annepidem.2019.01.010. Epub 2019 Jan 26.


Association between the vaginal microbiota, menopause status, and signs of vulvovaginal atrophy.

Brotman RM, Shardell MD, Gajer P, Fadrosh D, Chang K, Silver MI, Viscidi RP, Burke AE, Ravel J, Gravitt PE.

Menopause. 2018 Nov;25(11):1321-1330. doi: 10.1097/GME.0000000000001236.


Treatment of bacterial vaginosis to prevent preterm birth.

Klebanoff MA, Brotman RM.

Lancet. 2018 Nov 17;392(10160):2141-2142. doi: 10.1016/S0140-6736(18)32115-9. Epub 2018 Oct 12. No abstract available.


Phthalate exposure and odds of bacterial vaginosis among U.S. reproductive-aged women, NHANES 2001-2004.

Geller RJ, Brotman RM, O'Brien KM, Fine DM, Zota AR.

Reprod Toxicol. 2018 Dec;82:1-9. doi: 10.1016/j.reprotox.2018.09.001. Epub 2018 Sep 9.


The role of sexual networks in studies of how BV and STIs increase the risk of subsequent reinfection.

Kenyon C, Buyze J, Klebanoff M, Brotman RM.

Epidemiol Infect. 2018 Nov;146(15):2003-2009. doi: 10.1017/S0950268818002157. Epub 2018 Sep 5.


Higher Levels of a Cytotoxic Protein, Vaginolysin, in Lactobacillus-Deficient Community State Types at the Vaginal Mucosa.

Nowak RG, Randis TM, Desai P, He X, Robinson CK, Rath JM, Glover ED, Ratner AJ, Ravel J, Brotman RM.

Sex Transm Dis. 2018 Apr;45(4):e14-e17. doi: 10.1097/OLQ.0000000000000774.


Cigarette smoking is associated with an altered vaginal tract metabolomic profile.

Nelson TM, Borgogna JC, Michalek RD, Roberts DW, Rath JM, Glover ED, Ravel J, Shardell MD, Yeoman CJ, Brotman RM.

Sci Rep. 2018 Jan 16;8(1):852. doi: 10.1038/s41598-017-14943-3.


Incident Trichomonas vaginalis Is Associated With Partnership Concurrency: A Longitudinal Cohort Study.

Kenyon CR, Buyze J, Klebanoff M, Brotman RM.

Sex Transm Dis. 2017 Nov;44(11):695-699. doi: 10.1097/OLQ.0000000000000668.


Association between bacterial vaginosis and partner concurrency: a longitudinal study.

Kenyon CR, Buyze J, Klebanoff M, Brotman RM.

Sex Transm Infect. 2018 Feb;94(1):75-77. doi: 10.1136/sextrans-2016-052652. Epub 2016 Sep 19.


Intricacies of assessing the human microbiome in epidemiologic studies.

Robinson CK, Brotman RM, Ravel J.

Ann Epidemiol. 2016 May;26(5):311-21. doi: 10.1016/j.annepidem.2016.04.005. Epub 2016 Apr 12. Review.


Translating the vaginal microbiome: gaps and challenges.

Ravel J, Brotman RM.

Genome Med. 2016 Apr 1;8(1):35. doi: 10.1186/s13073-016-0291-2.


Vaginal biogenic amines: biomarkers of bacterial vaginosis or precursors to vaginal dysbiosis?

Nelson TM, Borgogna JL, Brotman RM, Ravel J, Walk ST, Yeoman CJ.

Front Physiol. 2015 Sep 29;6:253. doi: 10.3389/fphys.2015.00253. eCollection 2015.


Making inroads into improving treatment of bacterial vaginosis - striving for long-term cure.

Bradshaw CS, Brotman RM.

BMC Infect Dis. 2015 Jul 29;15:292. doi: 10.1186/s12879-015-1027-4. Review.


Prevalent high-risk HPV infection and vaginal microbiota in Nigerian women.

Dareng EO, Ma B, Famooto AO, Adebamowo SN, Offiong RA, Olaniyan O, Dakum PS, Wheeler CM, Fadrosh D, Yang H, Gajer P, Brotman RM, Ravel J, Adebamowo CA.

Epidemiol Infect. 2016 Jan;144(1):123-37. doi: 10.1017/S0950268815000965. Epub 2015 Jun 11.


Association between cigarette smoking and the vaginal microbiota: a pilot study.

Brotman RM, He X, Gajer P, Fadrosh D, Sharma E, Mongodin EF, Ravel J, Glover ED, Rath JM.

BMC Infect Dis. 2014 Aug 28;14:471. doi: 10.1186/1471-2334-14-471.


Interplay between the temporal dynamics of the vaginal microbiota and human papillomavirus detection.

Brotman RM, Shardell MD, Gajer P, Tracy JK, Zenilman JM, Ravel J, Gravitt PE.

J Infect Dis. 2014 Dec 1;210(11):1723-33. doi: 10.1093/infdis/jiu330. Epub 2014 Jun 18.


An improved dual-indexing approach for multiplexed 16S rRNA gene sequencing on the Illumina MiSeq platform.

Fadrosh DW, Ma B, Gajer P, Sengamalay N, Ott S, Brotman RM, Ravel J.

Microbiome. 2014 Feb 24;2(1):6. doi: 10.1186/2049-2618-2-6.


Daily temporal dynamics of vaginal microbiota before, during and after episodes of bacterial vaginosis.

Ravel J, Brotman RM, Gajer P, Ma B, Nandy M, Fadrosh DW, Sakamoto J, Koenig SS, Fu L, Zhou X, Hickey RJ, Schwebke JR, Forney LJ.

Microbiome. 2013 Dec 2;1(1):29. doi: 10.1186/2049-2618-1-29.


Microbiome, sex hormones, and immune responses in the reproductive tract: challenges for vaccine development against sexually transmitted infections.

Brotman RM, Ravel J, Bavoil PM, Gravitt PE, Ghanem KG.

Vaccine. 2014 Mar 20;32(14):1543-52. doi: 10.1016/j.vaccine.2013.10.010. Epub 2013 Oct 14.


Characterizing the temporal dynamics of human papillomavirus DNA detectability using short-interval sampling.

Liu SH, Cummings DA, Zenilman JM, Gravitt PE, Brotman RM.

Cancer Epidemiol Biomarkers Prev. 2014 Jan;23(1):200-8. doi: 10.1158/1055-9965.EPI-13-0666. Epub 2013 Oct 15.


Association between the vaginal microbiota, menopause status, and signs of vulvovaginal atrophy.

Brotman RM, Shardell MD, Gajer P, Fadrosh D, Chang K, Silver MI, Viscidi RP, Burke AE, Ravel J, Gravitt PE.

Menopause. 2014 May;21(5):450-8. doi: 10.1097/GME.0b013e3182a4690b.


Menstrual cycle and detectable human papillomavirus in reproductive-age women: a time series study.

Liu SH, Brotman RM, Zenilman JM, Gravitt PE, Cummings DA.

J Infect Dis. 2013 Nov 1;208(9):1404-15. doi: 10.1093/infdis/jit337. Epub 2013 Jul 24.


Association between Trichomonas vaginalis and vaginal bacterial community composition among reproductive-age women.

Brotman RM, Bradford LL, Conrad M, Gajer P, Ault K, Peralta L, Forney LJ, Carlton JM, Abdo Z, Ravel J.

Sex Transm Dis. 2012 Oct;39(10):807-12.


Comparison of storage conditions for human vaginal microbiome studies.

Bai G, Gajer P, Nandy M, Ma B, Yang H, Sakamoto J, Blanchard MH, Ravel J, Brotman RM.

PLoS One. 2012;7(5):e36934. doi: 10.1371/journal.pone.0036934. Epub 2012 May 24.


Temporal dynamics of the human vaginal microbiota.

Gajer P, Brotman RM, Bai G, Sakamoto J, Schütte UM, Zhong X, Koenig SS, Fu L, Ma ZS, Zhou X, Abdo Z, Forney LJ, Ravel J.

Sci Transl Med. 2012 May 2;4(132):132ra52. doi: 10.1126/scitranslmed.3003605.


Vaginal microbiome and sexually transmitted infections: an epidemiologic perspective.

Brotman RM.

J Clin Invest. 2011 Dec;121(12):4610-7. doi: 10.1172/JCI57172. Epub 2011 Dec 1. Review.


A case control study of anovaginal distance and bacterial vaginosis.

Brotman RM, Melendez JH, Ghanem KG.

Int J STD AIDS. 2011 Apr;22(4):231-3. doi: 10.1258/ijsa.2011.010307.


Recent advances in understanding the microbiology of the female reproductive tract and the causes of premature birth.

Zhou X, Brotman RM, Gajer P, Abdo Z, Schüette U, Ma S, Ravel J, Forney LJ.

Infect Dis Obstet Gynecol. 2010;2010:737425. doi: 10.1155/2010/737425. Epub 2010 Dec 9. Review.


Bacterial vaginosis assessed by gram stain and diminished colonization resistance to incident gonococcal, chlamydial, and trichomonal genital infection.

Brotman RM, Klebanoff MA, Nansel TR, Yu KF, Andrews WW, Zhang J, Schwebke JR.

J Infect Dis. 2010 Dec 15;202(12):1907-15. doi: 10.1086/657320. Epub 2010 Nov 10.


Rapid fluctuation of the vaginal microbiota measured by Gram stain analysis.

Brotman RM, Ravel J, Cone RA, Zenilman JM.

Sex Transm Infect. 2010 Aug;86(4):297-302. doi: 10.1136/sti.2009.040592.


Vaginal microbiome of reproductive-age women.

Ravel J, Gajer P, Abdo Z, Schneider GM, Koenig SS, McCulle SL, Karlebach S, Gorle R, Russell J, Tacket CO, Brotman RM, Davis CC, Ault K, Peralta L, Forney LJ.

Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4680-7. doi: 10.1073/pnas.1002611107. Epub 2010 Jun 3.

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