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Items: 17

1.

In vitro resistance study of rupintrivir, a novel inhibitor of human rhinovirus 3C protease.

Binford SL, Weady PT, Maldonado F, Brothers MA, Matthews DA, Patick AK.

Antimicrob Agents Chemother. 2007 Dec;51(12):4366-73. Epub 2007 Oct 1.

2.

In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease.

Patick AK, Brothers MA, Maldonado F, Binford S, Maldonado O, Fuhrman S, Petersen A, Smith GJ 3rd, Zalman LS, Burns-Naas LA, Tran JQ.

Antimicrob Agents Chemother. 2005 Jun;49(6):2267-75.

3.

Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor.

Binford SL, Maldonado F, Brothers MA, Weady PT, Zalman LS, Meador JW 3rd, Matthews DA, Patick AK.

Antimicrob Agents Chemother. 2005 Feb;49(2):619-26.

4.

Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors.

Webber SE, Marakovits JT, Dragovich PS, Prins TJ, Zhou R, Fuhrman SA, Patick AK, Matthews DA, Lee CA, Srinivasan B, Moran T, Ford CE, Brothers MA, Harr JE, Meador JW 3rd, Ferre RA, Worland ST.

Bioorg Med Chem Lett. 2001 Oct 22;11(20):2683-6.

PMID:
11591501
5.

Inhibition of human rhinovirus-induced cytokine production by AG7088, a human rhinovirus 3C protease inhibitor.

Zalman LS, Brothers MA, Dragovich PS, Zhou R, Prins TJ, Worland ST, Patick AK.

Antimicrob Agents Chemother. 2000 May;44(5):1236-41.

6.

Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors.

Dragovich PS, Zhou R, Webber SE, Prins TJ, Kwok AK, Okano K, Fuhrman SA, Zalman LS, Maldonado FC, Brown EL, Meador JW 3rd, Patick AK, Ford CE, Brothers MA, Binford SL, Matthews DA, Ferre RA, Worland ST.

Bioorg Med Chem Lett. 2000 Jan 3;10(1):45-8.

PMID:
10636240
7.

In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease.

Patick AK, Binford SL, Brothers MA, Jackson RL, Ford CE, Diem MD, Maldonado F, Dragovich PS, Zhou R, Prins TJ, Fuhrman SA, Meador JW, Zalman LS, Matthews DA, Worland ST.

Antimicrob Agents Chemother. 1999 Oct;43(10):2444-50.

8.

Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes.

Matthews DA, Dragovich PS, Webber SE, Fuhrman SA, Patick AK, Zalman LS, Hendrickson TF, Love RA, Prins TJ, Marakovits JT, Zhou R, Tikhe J, Ford CE, Meador JW, Ferre RA, Brown EL, Binford SL, Brothers MA, DeLisle DM, Worland ST.

Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11000-7.

9.

Induction in vitro of a primary human antiviral cytotoxic T cell response.

Cerny A, Fowler P, Brothers MA, Houghton M, Schlicht HJ, Chisari FV.

Eur J Immunol. 1995 Feb;25(2):627-30.

PMID:
7875224
10.

Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif.

Cerny A, McHutchison JG, Pasquinelli C, Brown ME, Brothers MA, Grabscheid B, Fowler P, Houghton M, Chisari FV.

J Clin Invest. 1995 Feb;95(2):521-30.

11.

Inhibition of cytolytic lymphocytes by homologous restriction factor. Lack of species restriction.

Zalman LS, Brothers MA, Strauss KL.

J Immunol. 1991 Jun 15;146(12):4278-81.

PMID:
1904077
12.

Isolation of homologous restriction factor from human urine. Immunochemical properties and biologic activity.

Zalman LS, Brothers MA, Müller-Eberhard HJ.

J Immunol. 1989 Sep 15;143(6):1943-7.

PMID:
2476489
13.

Self-protection of cytotoxic lymphocytes: a soluble form of homologous restriction factor in cytoplasmic granules.

Zalman LS, Brothers MA, Müller-Eberhard HJ.

Proc Natl Acad Sci U S A. 1988 Jul;85(13):4827-31.

14.
15.

A C9 related channel forming protein in the cytoplasmic granules of human large granular lymphocytes.

Zalman LS, Brothers MA, Müller-Eberhard HJ.

Biosci Rep. 1985 Dec;5(12):1093-100.

PMID:
3830274
16.

The role of C3 fragments in endocytosis and extracellular cytotoxic reactions by polymorphonuclear leukocytes.

Schreiber RD, Pangburn MK, Bjornson AB, Brothers MA, Müller-Eberhard HJ.

Clin Immunol Immunopathol. 1982 May;23(2):335-57. No abstract available.

PMID:
7049467
17.

Evaluation of low back pain by differential spinal block.

Brothers MA, Finlayson DC.

Can Anaesth Soc J. 1968 Sep;15(5):478-81. No abstract available.

PMID:
4234567

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