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Items: 48

1.

G-quadruplex deconvolution with physiological mimicry enhances primary screening: Optimizing the FRET Melt2 assay.

Morgan RK, Psaras AM, Lassiter Q, Raymer K, Brooks TA.

Biochim Biophys Acta Gene Regul Mech. 2020 Jan;1863(1):194478. doi: 10.1016/j.bbagrm.2019.194478. Epub 2019 Dec 28.

PMID:
31891781
2.

Co-Localization of DNA i-Motif-Forming Sequences and 5-Hydroxymethyl-cytosines in Human Embryonic Stem Cells.

Bhavsar-Jog YP, Van Dornshuld E, Brooks TA, Tschumper GS, Wadkins RM.

Molecules. 2019 Oct 8;24(19). pii: E3619. doi: 10.3390/molecules24193619.

3.

The comorbidities of dysmenorrhea: a clinical survey comparing symptom profile in women with and without endometriosis.

Evans SF, Brooks TA, Esterman AJ, Hull ML, Rolan PE.

J Pain Res. 2018 Dec 13;11:3181-3194. doi: 10.2147/JPR.S179409. eCollection 2018.

4.

Qualitative and quantitative drug residue analyses: Chlortetracycline in white-tailed deer (Odocoileus virginianus) and supermarket meat by liquid chromatography tandem-mass spectrometry.

Anderson SC, Subbiah S, Gentles A, Oliver D, Stonum P, Brooks TA, Smith EE.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:237-243. doi: 10.1016/j.jchromb.2018.05.027. Epub 2018 May 18.

PMID:
29913335
5.

Effects of 5-Hydroxymethylcytosine Epigenetic Modification on the Stability and Molecular Recognition of VEGF i-Motif and G-Quadruplex Structures.

Morgan RK, Molnar MM, Batra H, Summerford B, Wadkins RM, Brooks TA.

J Nucleic Acids. 2018 May 16;2018:9281286. doi: 10.1155/2018/9281286. eCollection 2018.

6.

Relationship between Environmental Enrichment and the Response to Novelty in Laboratory-housed Pigs.

Backus BL, Sutherland MA, Brooks TA.

J Am Assoc Lab Anim Sci. 2017 Nov 1;56(6):735-741.

7.

RAFT Polymerization for the Synthesis of Tertiary Amine-Based Diblock Copolymer Nucleic Acid Delivery Vehicles.

McClellan AK, Hao T, Brooks TA, Smith AE.

Macromol Biosci. 2017 Dec;17(12). doi: 10.1002/mabi.201700225. Epub 2017 Nov 15.

PMID:
29139616
8.

Despite Boosting Children's Coverage Rates To Historic Levels, Medicaid And CHIP Face An Uncertain Future.

Brooks TA.

Health Aff (Millwood). 2017 Sep 1;36(9):1652-1655. doi: 10.1377/hlthaff.2017.0929.

PMID:
28874494
9.

Nucleic acid clamp-mediated recognition and stabilization of the physiologically relevant MYC promoter G-quadruplex.

Hao T, Gaerig VC, Brooks TA.

Nucleic Acids Res. 2016 Dec 15;44(22):11013-11023. Epub 2016 Oct 26.

10.

Qualitative and Quantitative Drug residue analyses: Florfenicol in white-tailed deer (Odocoileus virginianus) and supermarket meat by liquid chromatography tandem-mass spectrometry.

Anderson SC, Subbiah S, Gentles A, Austin G, Stonum P, Brooks TA, Brooks C, Smith EE.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 15;1033-1034:73-79. doi: 10.1016/j.jchromb.2016.08.014. Epub 2016 Aug 10.

PMID:
27529828
11.

Identification and characterization of a new G-quadruplex forming region within the kRAS promoter as a transcriptional regulator.

Morgan RK, Batra H, Gaerig VC, Hockings J, Brooks TA.

Biochim Biophys Acta. 2016 Feb;1859(2):235-45. doi: 10.1016/j.bbagrm.2015.11.004. Epub 2015 Nov 18.

PMID:
26597160
12.

Effect of interior loop length on the thermal stability and pK(a) of i-motif DNA.

Reilly SM, Morgan RK, Brooks TA, Wadkins RM.

Biochemistry. 2015 Feb 17;54(6):1364-70. doi: 10.1021/bi5014722. Epub 2015 Feb 3.

13.

Open enrollment, take two.

Brooks TA.

Health Aff (Millwood). 2014 Jun;33(6):927-30. doi: 10.1377/hlthaff.2014.0415. No abstract available.

PMID:
24889940
14.

Epigenetic modification, dehydration, and molecular crowding effects on the thermodynamics of i-motif structure formation from C-rich DNA.

Bhavsar-Jog YP, Van Dornshuld E, Brooks TA, Tschumper GS, Wadkins RM.

Biochemistry. 2014 Mar 18;53(10):1586-94. doi: 10.1021/bi401523b. Epub 2014 Mar 6.

15.

Helping Eve overcome ADAM: G-quadruplexes in the ADAM-15 promoter as new molecular targets for breast cancer therapeutics.

Brown RV, Gaerig VC, Simmons T, Brooks TA.

Molecules. 2013 Dec 5;18(12):15019-34. doi: 10.3390/molecules181215019.

16.

Storage length, storage temperature, and lean formulation influence the shelf-life and stability of traditionally packaged ground beef.

Martin JN, Brooks JC, Brooks TA, Legako JF, Starkey JD, Jackson SP, Miller MF.

Meat Sci. 2013 Nov;95(3):495-502. doi: 10.1016/j.meatsci.2013.05.032. Epub 2013 May 25.

PMID:
23793085
17.

Effect of castration and dehorning singularly or combined on the behavior and physiology of Holstein calves.

Sutherland MA, Ballou MA, Davis BL, Brooks TA.

J Anim Sci. 2013 Feb;91(2):935-42. doi: 10.2527/jas.2012-5190. Epub 2013 Jan 3.

PMID:
23287529
18.

Administration of anesthetic and analgesic prevent the suppression of many leukocyte responses following surgical castration and physical dehorning.

Ballou MA, Sutherland MA, Brooks TA, Hulbert LE, Davis BL, Cobb CJ.

Vet Immunol Immunopathol. 2013 Feb 15;151(3-4):285-93. doi: 10.1016/j.vetimm.2012.11.018. Epub 2012 Dec 5.

PMID:
23270586
19.

Anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinylquindoline is not dependent on direct targeting of the G-quadruplex in the c-MYC promoter.

Boddupally PV, Hahn S, Beman C, De B, Brooks TA, Gokhale V, Hurley LH.

J Med Chem. 2012 Jul 12;55(13):6076-86. doi: 10.1021/jm300282c. Epub 2012 Jun 25.

20.

The physiological and behavioral response of pigs castrated with and without anesthesia or analgesia.

Sutherland MA, Davis BL, Brooks TA, Coetzee JF.

J Anim Sci. 2012 Jul;90(7):2211-21. doi: 10.2527/jas.2011-4260. Epub 2012 Jan 20.

PMID:
22266989
21.

Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex.

Brown RV, Danford FL, Gokhale V, Hurley LH, Brooks TA.

J Biol Chem. 2011 Nov 25;286(47):41018-27. doi: 10.1074/jbc.M111.274720. Epub 2011 Sep 28.

22.

Physiology and behavior of pigs before and after castration: effects of two topical anesthetics.

Sutherland MA, Davis BL, Brooks TA, McGlone JJ.

Animal. 2010 Dec;4(12):2071-9. doi: 10.1017/S1751731110001291.

PMID:
22445382
23.

Targeting MYC Expression through G-Quadruplexes.

Brooks TA, Hurley LH.

Genes Cancer. 2010 Jun;1(6):641-649.

24.

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

Brooks TA, Kendrick S, Hurley L.

FEBS J. 2010 Sep;277(17):3459-69. doi: 10.1111/j.1742-4658.2010.07759.x. Epub 2010 Jul 29. Review.

25.

Increased MYC gene copy number correlates with increased mRNA levels in diffuse large B-cell lymphoma.

Stasik CJ, Nitta H, Zhang W, Mosher CH, Cook JR, Tubbs RR, Unger JM, Brooks TA, Persky DO, Wilkinson ST, Grogan TM, Rimsza LM.

Haematologica. 2010 Apr;95(4):597-603. doi: 10.3324/haematol.2009.012864.

26.

Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression.

Qin Y, Fortin JS, Tye D, Gleason-Guzman M, Brooks TA, Hurley LH.

Biochemistry. 2010 May 18;49(19):4208-19. doi: 10.1021/bi100330w.

27.

The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics.

Brooks TA, Hurley LH.

Nat Rev Cancer. 2009 Dec;9(12):849-61. doi: 10.1038/nrc2733. Epub 2009 Nov 12. Review.

PMID:
19907434
28.

Chronic inflammatory pain and the neurovascular unit: a central role for glia in maintaining BBB integrity?

Willis CL, Brooks TA, Davis TP.

Curr Pharm Des. 2008;14(16):1625-43. Review. Erratum in: Curr Pharm Des. 2011;17(22):2367. Brooks, T A [added].

PMID:
18673205
29.

Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia.

McCaffrey G, Seelbach MJ, Staatz WD, Nametz N, Quigley C, Campos CR, Brooks TA, Davis TP.

J Neurochem. 2008 Sep;106(6):2395-409. doi: 10.1111/j.1471-4159.2008.05582.x. Epub 2008 Jul 21.

30.

Diclofenac attenuates the regional effect of lambda-carrageenan on blood-brain barrier function and cytoarchitecture.

Brooks TA, Nametz N, Charles R, Davis TP.

J Pharmacol Exp Ther. 2008 May;325(2):665-73. doi: 10.1124/jpet.107.135632. Epub 2008 Feb 27.

PMID:
18305016
31.

Tight junctions contain oligomeric protein assembly critical for maintaining blood-brain barrier integrity in vivo.

McCaffrey G, Staatz WD, Quigley CA, Nametz N, Seelbach MJ, Campos CR, Brooks TA, Egleton RD, Davis TP.

J Neurochem. 2007 Dec;103(6):2540-55. doi: 10.1111/j.1471-4159.2007.04943.x.

32.

Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: a role for P-glycoprotein.

Seelbach MJ, Brooks TA, Egleton RD, Davis TP.

J Neurochem. 2007 Sep;102(5):1677-1690. doi: 10.1111/j.1471-4159.2007.04644.x.

33.

The 4'-O-benzylated doxorubicin analog WP744 overcomes resistance mediated by P-glycoprotein, multidrug resistance protein and breast cancer resistance protein in cell lines and acute myeloid leukemia cells.

Brooks TA, O'Loughlin KL, Minderman H, Bundy BN, Ford LA, Vredenburg MR, Bernacki RJ, Priebe W, Baer MR.

Invest New Drugs. 2007 Apr;25(2):115-22. Epub 2006 Oct 28.

PMID:
17072745
34.

Biphasic cytoarchitecture and functional changes in the BBB induced by chronic inflammatory pain.

Brooks TA, Ocheltree SM, Seelbach MJ, Charles RA, Nametz N, Egleton RD, Davis TP.

Brain Res. 2006 Nov 20;1120(1):172-82. Epub 2006 Sep 27.

35.

Case study in canine intestinal lymphangiectasia.

Brooks TA.

Can Vet J. 2005 Dec;46(12):1138-42.

36.

Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations.

Brooks TA, Hawkins BT, Huber JD, Egleton RD, Davis TP.

Am J Physiol Heart Circ Physiol. 2005 Aug;289(2):H738-43. Epub 2005 Mar 25.

37.

Design, synthesis and structure-activity relationships of novel taxane-based multidrug resistance reversal agents.

Ojima I, Borella CP, Wu X, Bounaud PY, Oderda CF, Sturm M, Miller ML, Chakravarty S, Chen J, Huang Q, Pera P, Brooks TA, Baer MR, Bernacki RJ.

J Med Chem. 2005 Mar 24;48(6):2218-28.

PMID:
15771464
38.

Structure-activity analysis of taxane-based broad-spectrum multidrug resistance modulators.

Brooks TA, Kennedy DR, Gruol DJ, Ojima I, Baer MR, Bernacki RJ.

Anticancer Res. 2004 Mar-Apr;24(2A):409-15.

39.

Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.

Minderman H, Brooks TA, O'Loughlin KL, Ojima I, Bernacki RJ, Baer MR.

Cancer Chemother Pharmacol. 2004 May;53(5):363-9. Epub 2004 Jan 27.

PMID:
15060738
40.

Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein.

Brooks TA, Minderman H, O'Loughlin KL, Pera P, Ojima I, Baer MR, Bernacki RJ.

Mol Cancer Ther. 2003 Nov;2(11):1195-205. Erratum in: Mol Cancer Ther. 2004 Jan;3(1):101. Brooks, Tracy [corrected to Brooks, Tracy A].

41.

Construction and characterization of an effector strain of Streptococcus mutans for replacement therapy of dental caries.

Hillman JD, Brooks TA, Michalek SM, Harmon CC, Snoep JL, van Der Weijden CC.

Infect Immun. 2000 Feb;68(2):543-9.

42.

Genetic and biochemical analysis of mutacin 1140, a lantibiotic from Streptococcus mutans.

Hillman JD, Novák J, Sagura E, Gutierrez JA, Brooks TA, Crowley PJ, Hess M, Azizi A, Leung K, Cvitkovitch D, Bleiweis AS.

Infect Immun. 1998 Jun;66(6):2743-9.

43.

The changing world of malpractice coverage.

Brooks TA, McKee KR.

Mich Hosp. 1989 Mar;25(3):31-4, 36, 38. No abstract available.

PMID:
10292429
44.

Critique of Department of Justice review of mergers and other corporate combinations.

Felt JK, Brooks TA.

J Health Hosp Law. 1988 Jun;21(6):131-4. No abstract available.

PMID:
10287911
45.

Trustee responsibility.

Brooks TA.

Mich Hosp. 1981 May;17(5):16-8. No abstract available.

PMID:
10251143
46.

Legal and regulatory issues in hospice care.

Brooks TA.

Hosp Med Staff. 1980 Jun;9(6):15-21.

PMID:
10246863
47.

Michigan sets the pace for "voluntary effort" to contain costs.

Brooks TA.

Mich Hosp. 1978 May;14(5):9-10. No abstract available.

PMID:
10308437
48.

Capital report: National Health Resources and Development Act of 1974.

Brooks TA.

Osteopath Hosp. 1975 Feb;19(2):23-9. No abstract available.

PMID:
10246458

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