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Items: 1 to 50 of 163

1.

MITOCHONDRIAL REACTIVE OXYGEN SPECIES CONTRIBUTE TO PATHOLOGICAL INFLAMMATION DURING INFLUENZA A VIRUS INFECTION IN MICE.

To E, Erlich J, Liong F, Luong R, Liong S, Esaq F, Oseghale O, Anthony D, McQualter J, Bozinovski S, Vlahos R, O'Leary JJ, Brooks DA, Selemidis S.

Antioxid Redox Signal. 2019 Jun 13. doi: 10.1089/ars.2019.7727. [Epub ahead of print]

PMID:
31190565
2.

Development of a 13C Stable Isotope Assay for Dipeptidyl Peptidase-4 Enzyme Activity A New Breath Test for Dipeptidyl Peptidase Activity.

Yazbeck R, Jaenisch S, Squire M, Abbott CA, Parkinson-Lawrence E, Brooks DA, Butler RN.

Sci Rep. 2019 Mar 20;9(1):4906. doi: 10.1038/s41598-019-41375-y.

3.

Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period.

Lock MC, Darby JRT, Soo JY, Brooks DA, Perumal SR, Selvanayagam JB, Seed M, Macgowan CK, Porrello ER, Tellam RL, Morrison JL.

Front Physiol. 2019 Mar 5;10:208. doi: 10.3389/fphys.2019.00208. eCollection 2019.

4.

Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus-induced lung inflammation in mice.

To EE, Luong R, Diao J, O' Leary JJ, Brooks DA, Vlahos R, Selemidis S.

Respirology. 2019 Mar 18. doi: 10.1111/resp.13524. [Epub ahead of print]

PMID:
30884042
5.

Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice.

To EE, Erlich J, Liong F, Luong R, Liong S, Bozinovski S, Seow HJ, O'Leary JJ, Brooks DA, Vlahos R, Selemidis S.

Sci Rep. 2019 Feb 20;9(1):2366. doi: 10.1038/s41598-019-38864-5.

6.

Lipid profiles of prostate cancer cells.

Sorvina A, Bader CA, Caporale C, Carter EA, Johnson IRD, Parkinson-Lawrence EJ, Simpson PV, Wright PJ, Stagni S, Lay PA, Massi M, Brooks DA, Plush SE.

Oncotarget. 2018 Oct 30;9(85):35541-35552. doi: 10.18632/oncotarget.26222. eCollection 2018 Oct 30.

7.

NOX2 oxidase expressed in endosomes promotes cell proliferation and prostate tumour development.

Harrison IP, Vinh A, Johnson IRD, Luong R, Drummond GR, Sobey CG, Tiganis T, Williams ED, O' Leary JJ, Brooks DA, Selemidis S.

Oncotarget. 2018 Oct 23;9(83):35378-35393. doi: 10.18632/oncotarget.26237. eCollection 2018 Oct 23.

8.

Norbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membrane.

Hickey SM, Ashton TD, Boer G, Bader CA, Thomas M, Elliott AG, Schmuck C, Yu HY, Li J, Nation RL, Cooper MA, Plush SE, Brooks DA, Pfeffer FM.

Eur J Med Chem. 2018 Dec 5;160:9-22. doi: 10.1016/j.ejmech.2018.09.072. Epub 2018 Oct 3.

PMID:
30316060
9.

Mitochondrial imaging in live or fixed tissues using a luminescent iridium complex.

Sorvina A, Bader CA, Darby JRT, Lock MC, Soo JY, Johnson IRD, Caporale C, Voelcker NH, Stagni S, Massi M, Morrison JL, Plush SE, Brooks DA.

Sci Rep. 2018 May 29;8(1):8191. doi: 10.1038/s41598-018-24672-w.

10.

The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults.

Lock MC, Tellam RL, Botting KJ, Wang KCW, Selvanayagam JB, Brooks DA, Seed M, Morrison JL.

J Physiol. 2018 Dec;596(23):5625-5640. doi: 10.1113/JP276072. Epub 2018 Jun 28.

PMID:
29785790
11.

Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion.

Armstrong HK, Gillis JL, Johnson IRD, Nassar ZD, Moldovan M, Levrier C, Sadowski MC, Chin MY, Tomlinson Guns ES, Tarulli G, Lynn DJ, Brooks DA, Selth LA, Centenera MM, Butler LM.

Sci Rep. 2018 Feb 1;8(1):2090. doi: 10.1038/s41598-018-19871-4.

12.

Label-free imaging of redox status and collagen deposition showing metabolic differences in the heart.

Morrison JL, Sorvina A, Darby JRT, Bader CA, Lock MC, Seed M, Kuchel T, Plush SE, Brooks DA.

J Biophotonics. 2018 Mar;11(3). doi: 10.1002/jbio.201700242. Epub 2017 Nov 28.

PMID:
29057578
13.

Synthesis, photophysical and cellular characterisation of folate and methotrexate labelled luminescent lanthanide complexes.

Du Z, Sun J, Bader CA, Brooks DA, Li M, Li X, Plush SE.

J Inorg Biochem. 2018 Jan;178:32-42. doi: 10.1016/j.jinorgbio.2017.10.003. Epub 2017 Oct 10.

PMID:
29035716
14.

Investigating Intracellular Localisation and Cytotoxicity Trends for Neutral and Cationic Iridium Tetrazolato Complexes in Live Cells.

Caporale C, Bader CA, Sorvina A, MaGee KDM, Skelton BW, Gillam TA, Wright PJ, Raiteri P, Stagni S, Morrison JL, Plush SE, Brooks DA, Massi M.

Chemistry. 2017 Nov 7;23(62):15666-15679. doi: 10.1002/chem.201701352. Epub 2017 Aug 7.

PMID:
28782852
15.

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.

To EE, Vlahos R, Luong R, Halls ML, Reading PC, King PT, Chan C, Drummond GR, Sobey CG, Broughton BRS, Starkey MR, van der Sluis R, Lewin SR, Bozinovski S, O'Neill LAJ, Quach T, Porter CJH, Brooks DA, O'Leary JJ, Selemidis S.

Nat Commun. 2017 Jul 12;8(1):69. doi: 10.1038/s41467-017-00057-x.

16.

Imaging and lipidomics methods for lipid analysis in metabolic and cardiovascular disease.

Stevens KG, Bader CA, Sorvina A, Brooks DA, Plush SE, Morrison JL.

J Dev Orig Health Dis. 2017 Oct;8(5):566-574. doi: 10.1017/S2040174417000496. Epub 2017 Jul 12. Review.

PMID:
28697812
17.

Label-free imaging of healthy and infarcted fetal sheep hearts by two-photon microscopy.

Sorvina A, Bader CA, Lock MC, Brooks DA, Morrison JL, Plush SE.

J Biophotonics. 2018 Jan;11(1). doi: 10.1002/jbio.201600296. Epub 2017 May 2.

PMID:
28464439
18.

Proteome Analysis of Drosophila Mutants Identifies a Regulatory Role for 14-3-3ε in Metabolic Pathways.

Ng YS, Sorvina A, Bader CA, Weiland F, Lopez AF, Hoffmann P, Shandala T, Brooks DA.

J Proteome Res. 2017 May 5;16(5):1976-1987. doi: 10.1021/acs.jproteome.6b01032. Epub 2017 Apr 13.

PMID:
28365999
19.

Akt signaling as a mediator of cardiac adaptation to low birth weight.

Wang KC, Botting KJ, Zhang S, McMillen IC, Brooks DA, Morrison JL.

J Endocrinol. 2017 May;233(2):R81-R94. doi: 10.1530/JOE-17-0039. Epub 2017 Feb 20. Review.

PMID:
28219933
20.

Intracellular distribution and stability of a luminescent rhenium(i) tricarbonyl tetrazolato complex using epifluorescence microscopy in conjunction with X-ray fluorescence imaging.

Wedding JL, Harris HH, Bader CA, Plush SE, Mak R, Massi M, Brooks DA, Lai B, Vogt S, Werrett MV, Simpson PV, Skelton BW, Stagni S.

Metallomics. 2017 Apr 19;9(4):382-390. doi: 10.1039/c6mt00243a.

PMID:
27909710
21.

Targeting prostate cancer cells with genetically engineered polypeptide-based micelles displaying gastrin-releasing peptide.

Zhang W, Garg S, Eldi P, Zhou FH, Johnson IR, Brooks DA, Lam F, Rychkov G, Hayball J, Albrecht H.

Int J Pharm. 2016 Nov 20;513(1-2):270-279. doi: 10.1016/j.ijpharm.2016.09.039. Epub 2016 Sep 12.

PMID:
27633281
22.

The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470).

Hamdouchi C, Kahl SD, Patel Lewis A, Cardona GR, Zink RW, Chen K, Eessalu TE, Ficorilli JV, Marcelo MC, Otto KA, Wilbur KL, Lineswala JP, Piper JL, Coffey DS, Sweetana SA, Haas JV, Brooks DA, Pratt EJ, Belin RM, Deeg MA, Ma X, Cannady EA, Johnson JT, Yumibe NP, Chen Q, Maiti P, Montrose-Rafizadeh C, Chen Y, Reifel Miller A.

J Med Chem. 2016 Dec 22;59(24):10891-10916. doi: 10.1021/acs.jmedchem.6b00892. Epub 2016 Nov 11.

PMID:
27749056
23.

Drug induced exocytosis of glycogen in Pompe disease.

Turner CT, Fuller M, Hopwood JJ, Meikle PJ, Brooks DA.

Biochem Biophys Res Commun. 2016 Oct 28;479(4):721-727. doi: 10.1016/j.bbrc.2016.09.145. Epub 2016 Sep 28.

PMID:
27693584
24.

A Molecular Probe for the Detection of Polar Lipids in Live Cells.

Bader CA, Shandala T, Carter EA, Ivask A, Guinan T, Hickey SM, Werrett MV, Wright PJ, Simpson PV, Stagni S, Voelcker NH, Lay PA, Massi M, Plush SE, Brooks DA.

PLoS One. 2016 Aug 23;11(8):e0161557. doi: 10.1371/journal.pone.0161557. eCollection 2016.

25.

Imaging nuclear, endoplasmic reticulum and plasma membrane events in real time.

Bader CA, Sorvina A, Simpson PV, Wright PJ, Stagni S, Plush SE, Massi M, Brooks DA.

FEBS Lett. 2016 Sep;590(18):3051-60. doi: 10.1002/1873-3468.12365. Epub 2016 Sep 10.

26.

Drosophila Pkaap regulates Rab4/Rab11-dependent traffic and Rab11 exocytosis of innate immune cargo.

Sorvina A, Shandala T, Brooks DA.

Biol Open. 2016 Jun 15;5(6):678-88. doi: 10.1242/bio.016642.

27.

Unprecedented staining of polar lipids by a luminescent rhenium complex revealed by FTIR microspectroscopy in adipocytes.

Bader CA, Carter EA, Safitri A, Simpson PV, Wright P, Stagni S, Massi M, Lay PA, Brooks DA, Plush SE.

Mol Biosyst. 2016 Jun 21;12(7):2064-8. doi: 10.1039/c6mb00242k.

PMID:
27170554
28.

Endosomal gene expression: a new indicator for prostate cancer patient prognosis?

Johnson IR, Parkinson-Lawrence EJ, Keegan H, Spillane CD, Barry-O'Crowley J, Watson WR, Selemidis S, Butler LM, O'Leary JJ, Brooks DA.

Oncotarget. 2015 Nov 10;6(35):37919-29. doi: 10.18632/oncotarget.6114.

29.

Atg9 is required for intraluminal vesicles in amphisomes and autolysosomes.

Bader CA, Shandala T, Ng YS, Johnson IR, Brooks DA.

Biol Open. 2015 Sep 9;4(11):1345-55. doi: 10.1242/bio.013979.

30.

Regulation of microRNA during cardiomyocyte maturation in sheep.

Morrison JL, Zhang S, Tellam RL, Brooks DA, McMillen IC, Porrello ER, Botting KJ.

BMC Genomics. 2015 Jul 22;16:541. doi: 10.1186/s12864-015-1693-z.

31.

Low birth weight activates the renin-angiotensin system, but limits cardiac angiogenesis in early postnatal life.

Wang KC, Brooks DA, Summers-Pearce B, Bobrovskaya L, Tosh DN, Duffield JA, Botting KJ, Zhang S, Caroline McMillen I, Morrison JL.

Physiol Rep. 2015 Feb 3;3(2). pii: e12270. doi: 10.14814/phy2.12270. Print 2015 Feb 1.

32.

IGF-2R-Gαq signaling and cardiac hypertrophy in the low-birth-weight lamb.

Wang KC, Tosh DN, Zhang S, McMillen IC, Duffield JA, Brooks DA, Morrison JL.

Am J Physiol Regul Integr Comp Physiol. 2015 Apr 1;308(7):R627-35. doi: 10.1152/ajpregu.00346.2014. Epub 2015 Jan 28.

33.

Absence of α-galactosidase cross-correction in Fabry heterozygote cultured skin fibroblasts.

Fuller M, Mellett N, Hein LK, Brooks DA, Meikle PJ.

Mol Genet Metab. 2015 Feb;114(2):268-73. doi: 10.1016/j.ymgme.2014.11.005. Epub 2014 Nov 12.

PMID:
25468650
34.

Altered endosome biogenesis in prostate cancer has biomarker potential.

Johnson IR, Parkinson-Lawrence EJ, Shandala T, Weigert R, Butler LM, Brooks DA.

Mol Cancer Res. 2014 Dec;12(12):1851-62. doi: 10.1158/1541-7786.MCR-14-0074. Epub 2014 Jul 30.

35.

Prostate cell lines as models for biomarker discovery: performance of current markers and the search for new biomarkers.

Johnson IR, Parkinson-Lawrence EJ, Butler LM, Brooks DA.

Prostate. 2014 May;74(5):547-60. doi: 10.1002/pros.22777. Epub 2014 Jan 16.

PMID:
24435746
36.

Aminoglycoside-Induced Premature Stop Codon Read-Through of Mucopolysaccharidosis Type I Patient Q70X and W402X Mutations in Cultured Cells.

Kamei M, Kasperski K, Fuller M, Parkinson-Lawrence EJ, Karageorgos L, Belakhov V, Baasov T, Hopwood JJ, Brooks DA.

JIMD Rep. 2014;13:139-47. doi: 10.1007/8904_2013_270. Epub 2013 Nov 6.

37.

Alteration of cardiac glucose metabolism in association to low birth weight: experimental evidence in lambs with left ventricular hypertrophy.

Wang KC, Lim CH, McMillen IC, Duffield JA, Brooks DA, Morrison JL.

Metabolism. 2013 Nov;62(11):1662-72. doi: 10.1016/j.metabol.2013.06.013. Epub 2013 Aug 5.

PMID:
23928106
38.

Transcranial magnetic stimulation--may be useful as a preoperative screen of motor tract function.

Galloway GM, Dias BR, Brown JL, Henry CM, Brooks DA 2nd, Buggie EW.

J Clin Neurophysiol. 2013 Aug;30(4):386-9. doi: 10.1097/WNP.0b013e31829ddeb2.

PMID:
23912578
39.

Developmental changes and fructose absorption in children: effect on malabsorption testing and dietary management.

Jones HF, Butler RN, Moore DJ, Brooks DA.

Nutr Rev. 2013 May;71(5):300-9. doi: 10.1111/nure.12020. Review.

PMID:
23590706
40.

An electroolfactogram study of odor response patterns from the mouse olfactory epithelium with reference to receptor zones and odor sorptiveness.

Coppola DM, Waggener CT, Radwani SM, Brooks DA.

J Neurophysiol. 2013 Apr;109(8):2179-91. doi: 10.1152/jn.00769.2012. Epub 2013 Jan 23.

41.

A Drosophila model to image phagosome maturation.

Shandala T, Lim C, Sorvina A, Brooks DA.

Cells. 2013 Mar 26;2(2):188-201. doi: 10.3390/cells2020188.

42.

Exocytosis is impaired in mucopolysaccharidosis IIIA mouse chromaffin cells.

Keating DJ, Winter MA, Hemsley KM, Mackenzie KD, Teo EH, Hopwood JJ, Brooks DA, Parkinson-Lawrence EJ.

Neuroscience. 2012 Dec 27;227:110-8. doi: 10.1016/j.neuroscience.2012.09.034. Epub 2012 Sep 25.

PMID:
23022219
43.

Activation of IGF-2R stimulates cardiomyocyte hypertrophy in the late gestation sheep fetus.

Wang KC, Brooks DA, Thornburg KL, Morrison JL.

J Physiol. 2012 Nov 1;590(21):5425-37. doi: 10.1113/jphysiol.2012.238410. Epub 2012 Aug 28.

44.

Innate immunity and exocytosis of antimicrobial peptides.

Shandala T, Brooks DA.

Commun Integr Biol. 2012 Mar 1;5(2):214-6. doi: 10.4161/cib.19018.

45.

Early origins of heart disease: low birth weight and the role of the insulin-like growth factor system in cardiac hypertrophy.

Wang KC, Botting KJ, Padhee M, Zhang S, McMillen IC, Suter CM, Brooks DA, Morrison JL.

Clin Exp Pharmacol Physiol. 2012 Nov;39(11):958-64. doi: 10.1111/j.1440-1681.2012.05743.x. Review.

PMID:
22774980
46.

A role for altered phagosome maturation in the long-term persistence of Helicobacter pylori infection.

Borlace GN, Keep SJ, Prodoehl MJ, Jones HF, Butler RN, Brooks DA.

Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15;303(2):G169-79. doi: 10.1152/ajpgi.00320.2011. Epub 2012 May 10. Review.

47.

IGF-2R-mediated signaling results in hypertrophy of cultured cardiomyocytes from fetal sheep.

Wang KC, Brooks DA, Botting KJ, Morrison JL.

Biol Reprod. 2012 Jun 22;86(6):183. doi: 10.1095/biolreprod.112.100388. Print 2012 Jun.

PMID:
22441800
48.

Neonatal gene therapy with a gamma retroviral vector in mucopolysaccharidosis VI cats.

Ponder KP, O'Malley TM, Wang P, O'Donnell PA, Traas AM, Knox VW, Aguirre GA, Ellinwood NM, Metcalf JA, Wang B, Parkinson-Lawrence EJ, Sleeper MM, Brooks DA, Hopwood JJ, Haskins ME.

Mol Ther. 2012 May;20(5):898-907. doi: 10.1038/mt.2012.9. Epub 2012 Mar 6.

49.

Mass spectrometric quantification of glycogen to assess primary substrate accumulation in the Pompe mouse.

Fuller M, Duplock S, Turner C, Davey P, Brooks DA, Hopwood JJ, Meikle PJ.

Anal Biochem. 2012 Feb 15;421(2):759-63. doi: 10.1016/j.ab.2011.12.026. Epub 2011 Dec 20.

PMID:
22239964
50.

Early origins of heart disease: low birth weight and determinants of cardiomyocyte endowment.

Botting KJ, Wang KC, Padhee M, McMillen IC, Summers-Pearce B, Rattanatray L, Cutri N, Posterino GS, Brooks DA, Morrison JL.

Clin Exp Pharmacol Physiol. 2012 Sep;39(9):814-23. doi: 10.1111/j.1440-1681.2011.05649.x. Review.

PMID:
22126336

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