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Items: 1 to 50 of 1610

1.

Enhanced Sampling Applied to Modeling Allosteric Regulation in Transcription.

Wang Y, Brooks CL.

J Phys Chem Lett. 2019 Sep 19. doi: 10.1021/acs.jpclett.9b02226. [Epub ahead of print]

PMID:
31535860
2.

Discovery of GSK3527497: A candidate for the inhibition of Transient Receptor Potential Vanilloid-4 (TRPV4).

Brooks CA, Barton LS, Behm DJ, Brnardic E, Costell M, Holt DA, Jolivette LJ, Matthews JM, McAtee JJ, McCleland BW, Patterson JR, Pero JE, Rivero RA, Roethke TJ, Sanchez RM, Shenje R, Terrell LR, Lawhorn BG.

J Med Chem. 2019 Sep 18. doi: 10.1021/acs.jmedchem.9b01247. [Epub ahead of print]

PMID:
31532662
3.

Hydroxyl Radical-Coupled Electron-Transfer Mechanism of Flavin-Dependent Hydroxylases.

Tweedy SE, Rodríguez Benítez A, Narayan ARH, Zimmerman PM, Brooks CL 3rd, Wymore T.

J Phys Chem B. 2019 Sep 18. doi: 10.1021/acs.jpcb.9b08178. [Epub ahead of print]

PMID:
31532200
4.

A Collaborative Academic-Practice Approach to Meeting Educational and Workforce Needs.

Maneval R, Browne KP, Feldman HR, Brooks C, Scuderi D, Henderson J, Epstein C.

J Nurs Adm. 2019 Oct;49(10):463-465. doi: 10.1097/NNA.0000000000000788.

PMID:
31517754
5.

Genetic Manipulation of Cryptosporidium parvum with CRISPR/Cas9.

Sateriale A, Pawlowic M, Vinayak S, Brooks C, Striepen B.

Methods Mol Biol. 2020;2052:219-228. doi: 10.1007/978-1-4939-9748-0_13.

PMID:
31452165
6.

Computational Studies of Catalytic Loop Dynamics in Yersinia Protein Tyrosine Phosphatase Using Pathway Optimization Methods.

Deng H, Ke S, Callender R, Balakrishnan G, Spiro TG, May ER, Brooks CL 3rd.

J Phys Chem B. 2019 Sep 19;123(37):7840-7851. doi: 10.1021/acs.jpcb.9b06759. Epub 2019 Sep 4.

7.

DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance.

Togami K, Pastika T, Stephansky J, Ghandi M, Christie AL, Jones KL, Johnson CA, Lindsay RW, Brooks CL, Letai A, Craig JW, Pozdnyakova O, Weinstock DM, Montero J, Aster JC, Johannessen CM, Lane AA.

J Clin Invest. 2019 Aug 22. pii: 128571. doi: 10.1172/JCI128571. [Epub ahead of print]

8.

Reply to: Transpyloric feeds and bronchopulmonary dysplasia.

Wallenstein MB, Brooks C, Kline TA, Beck RQ, Yang W, Shaw GM, Stevenson DK.

J Perinatol. 2019 Aug 20. doi: 10.1038/s41372-019-0458-y. [Epub ahead of print] No abstract available.

PMID:
31431655
9.

Development of a stratification tool to identify pancreatic intraductal papillary mucinous neoplasms at lowest risk of progression.

Overbeek KA, Alblas M, Gausman V, Kandel P, Schweber AB, Brooks C, Van Riet PA, Wallace MB, Gonda TA, Cahen DL, Bruno MJ.

Aliment Pharmacol Ther. 2019 Oct;50(7):789-799. doi: 10.1111/apt.15440. Epub 2019 Aug 19.

PMID:
31429105
10.

Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles.

Strand MS, Krasnick BA, Pan H, Zhang X, Bi Y, Brooks C, Wetzel C, Sankpal N, Fleming T, Goedegebuure SP, DeNardo DG, Gillanders WE, Hawkins WG, Wickline SA, Fields RC.

Oncotarget. 2019 Jul 30;10(46):4761-4775. doi: 10.18632/oncotarget.27109. eCollection 2019 Jul 30.

11.

Discovery of GSK2798745: A Clinical Candidate for Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4).

Brooks CA, Barton LS, Behm DJ, Eidam HS, Fox RM, Hammond M, Hoang TH, Holt DA, Hilfiker MA, Lawhorn BG, Patterson JR, Stoy P, Roethke TJ, Ye G, Zhao S, Thorneloe KS, Goodman KB, Cheung M.

ACS Med Chem Lett. 2019 Jul 15;10(8):1228-1233. doi: 10.1021/acsmedchemlett.9b00274. eCollection 2019 Aug 8.

PMID:
31413810
12.

Quantifying autophagic flux in kidney tissue using structured illumination microscopy.

Taguchi K, Elias BC, Qian S, Brooks CR.

Methods Cell Biol. 2019;153:231-253. doi: 10.1016/bs.mcb.2019.05.004. Epub 2019 Jun 25.

PMID:
31395381
13.

Overcoming Challenging Substituent Perturbations with Multisite λ-Dynamics: A Case Study Targeting β-Secretase 1.

Vilseck JZ, Sohail N, Hayes RL, Brooks CL 3rd.

J Phys Chem Lett. 2019 Aug 13:4875-4880. doi: 10.1021/acs.jpclett.9b02004. [Epub ahead of print]

PMID:
31386370
14.

Genetic structure at three spatial scales is consistent with limited philopatry in Ricord's Rock Iguanas (Cyclura ricordii).

Carreras-De León R, Pasachnik SA, Gerber GP, Brooks CP, Rupp E, Welch ME.

Ecol Evol. 2019 Jul 2;9(14):8331-8350. doi: 10.1002/ece3.5414. eCollection 2019 Jul.

15.

Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.

Benítez AR, Tweedy S, Baker Dockrey SA, Lukowski AL, Wymore T, Khare D, Brooks CL 3rd, Palfey BA, Smith JL, Narayan ARH.

ACS Catal. 2019 Apr 5;9(4):3633-3640. doi: 10.1021/acscatal.8b04575. Epub 2019 Mar 25.

PMID:
31346489
16.

Frustration and folding of a TIM barrel protein.

Halloran KT, Wang Y, Arora K, Chakravarthy S, Irving TC, Bilsel O, Brooks CL 3rd, Matthews CR.

Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16378-16383. doi: 10.1073/pnas.1900880116. Epub 2019 Jul 25.

PMID:
31346089
17.

Goal-directed resuscitation following cardiac surgery reduces acute kidney injury: A quality initiative pre-post analysis.

Johnston LE, Thiele RH, Hawkins RB, Downs EA, Jaeger JM, Brooks C, Ghanta RK, Ailawadi G, Kron IL, Isbell JM; Virginia Interdisciplinary Cardiothoracic Outcomes Research Center.

J Thorac Cardiovasc Surg. 2019 May 17. pii: S0022-5223(19)31029-3. doi: 10.1016/j.jtcvs.2019.03.135. [Epub ahead of print]

PMID:
31272751
18.

Positioning-Group-Enabled Biocatalytic Oxidative Dearomatization.

Dockrey SAB, Suh CE, Benítez AR, Wymore T, Brooks CL 3rd, Narayan ARH.

ACS Cent Sci. 2019 Jun 26;5(6):1010-1016. doi: 10.1021/acscentsci.9b00163. Epub 2019 Jun 12.

19.

Modeling pH-Dependent NMR Chemical Shift Perturbations in Peptides.

Artikis E, Brooks CL 3rd.

Biophys J. 2019 Jul 23;117(2):258-268. doi: 10.1016/j.bpj.2019.06.003. Epub 2019 Jun 12.

PMID:
31255294
20.

A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective Immunity.

Sateriale A, Šlapeta J, Baptista R, Engiles JB, Gullicksrud JA, Herbert GT, Brooks CF, Kugler EM, Kissinger JC, Hunter CA, Striepen B.

Cell Host Microbe. 2019 Jul 10;26(1):135-146.e5. doi: 10.1016/j.chom.2019.05.006. Epub 2019 Jun 20.

21.

Reply to: 'Early transyploric feeding: an old wine in a new bottle'.

Wallenstein MB, Brooks C, Kline TA, Beck RQ, Yang W, Shaw GM, Stevenson DK.

J Perinatol. 2019 Aug;39(8):1155-1156. doi: 10.1038/s41372-019-0418-6. Epub 2019 Jun 20. No abstract available.

PMID:
31222155
22.

Return to work after carpal tunnel release surgery: a qualitative interview study.

Newington L, Brooks C, Warwick D, Adams J, Walker-Bone K.

BMC Musculoskelet Disord. 2019 May 22;20(1):242. doi: 10.1186/s12891-019-2638-5.

23.

Temporal Trends in Medical Student Burnout.

Hansell MW, Ungerleider RM, Brooks CA, Knudson MP, Kirk JK, Ungerleider JD.

Fam Med. 2019 May;51(5):399-404. doi: 10.22454/FamMed.2019.270753.

24.

Does the Intra-Atomic Deformation Energy of Interacting Quantum Atoms Represent Steric Energy?

Symons BCB, Williamson DJ, Brooks CM, Wilson AL, Popelier PLA.

ChemistryOpen. 2019 Feb 8;8(5):560-570. doi: 10.1002/open.201800275. eCollection 2019 May.

25.

Does the Intra-atomic Deformation Energy of Interacting Quantum Atoms Represent Steric Energy?

Symons BCB, Williamson DJ, Brooks CM, Wilson AL, Popelier PLA.

ChemistryOpen. 2019 Apr 1;8(5):553. doi: 10.1002/open.201900096. eCollection 2019 May.

26.

Modified Collection Chamber for Controlled Silicone Oil Removal With Pars Plana Vitrectomy.

Brooks CC, Riemann CD.

Retina. 2019 Apr 24. doi: 10.1097/IAE.0000000000002549. [Epub ahead of print] No abstract available.

PMID:
31033864
27.

Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm.

Pemmaraju N, Lane AA, Sweet KL, Stein AS, Vasu S, Blum W, Rizzieri DA, Wang ES, Duvic M, Sloan JM, Spence S, Shemesh S, Brooks CL, Balser J, Bergstein I, Lancet JE, Kantarjian HM, Konopleva M.

N Engl J Med. 2019 Apr 25;380(17):1628-1637. doi: 10.1056/NEJMoa1815105.

PMID:
31018069
28.

Early transpyloric vs gastric feeding in preterm infants: a retrospective cohort study.

Wallenstein MB, Brooks C, Kline TA, Beck RQ, Yang W, Shaw GM, Stevenson DK.

J Perinatol. 2019 Jun;39(6):837-841. doi: 10.1038/s41372-019-0372-3. Epub 2019 Apr 9.

PMID:
30967655
29.

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Baragaña B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig JA, Pisco JP, Peet C, Dranow DM, Robinson DA, Jansen C, Norcross NR, Vinayak S, Anderson M, Brooks CF, Cooper CA, Damerow S, Delves M, Dowers K, Duffy J, Edwards TE, Hallyburton I, Horst BG, Hulverson MA, Ferguson L, Jiménez-Díaz MB, Jumani RS, Lorimer DD, Love MS, Maher S, Matthews H, McNamara CW, Miller P, O'Neill S, Ojo KK, Osuna-Cabello M, Pinto E, Post J, Riley J, Rottmann M, Sanz LM, Scullion P, Sharma A, Shepherd SM, Shishikura Y, Simeons FRC, Stebbins EE, Stojanovski L, Straschil U, Tamaki FK, Tamjar J, Torrie LS, Vantaux A, Witkowski B, Wittlin S, Yogavel M, Zuccotto F, Angulo-Barturen I, Sinden R, Baum J, Gamo FJ, Mäser P, Kyle DE, Winzeler EA, Myler PJ, Wyatt PG, Floyd D, Matthews D, Sharma A, Striepen B, Huston CD, Gray DW, Fairlamb AH, Pisliakov AV, Walpole C, Read KD, Van Voorhis WC, Gilbert IH.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7015-7020. doi: 10.1073/pnas.1814685116. Epub 2019 Mar 20.

30.

Structure of a VHH isolated from a naïve phage display library.

White B, Huh I, Brooks CL.

BMC Res Notes. 2019 Mar 19;12(1):154. doi: 10.1186/s13104-019-4197-0.

31.

Type of TP53 mutation influences oncogenic potential and spectrum of associated K-ras mutations in lung-specific transgenic mice.

Duan W, Gao L, Kalvala A, Aguila B, Brooks C, Mo X, Ding H, Shilo K, Otterson GA, Villalona-Calero MA.

Int J Cancer. 2019 Nov 1;145(9):2418-2426. doi: 10.1002/ijc.32279. Epub 2019 Apr 13.

PMID:
30873587
32.

Detection of critical antibiotic resistance genes through routine microbiome surveillance.

Burcham ZM, Schmidt CJ, Pechal JL, Brooks CP, Rosch JW, Benbow ME, Jordan HR.

PLoS One. 2019 Mar 14;14(3):e0213280. doi: 10.1371/journal.pone.0213280. eCollection 2019.

33.

TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance.

Lynch MR, Tran MT, Ralto KM, Zsengeller ZK, Raman V, Bhasin SS, Sun N, Chen X, Brown D, Rovira II, Taguchi K, Brooks CR, Stillman IE, Bhasin MK, Finkel T, Parikh SM.

JCI Insight. 2019 Mar 14;5. pii: 126749. doi: 10.1172/jci.insight.126749.

34.

Feasibility and acceptance of the CaringGuidance web-based, distress self-management, psychoeducational program initiated within 12 weeks of breast cancer diagnosis.

Lally RM, Bellavia G, Gallo S, Kupzyk K, Helgeson V, Brooks C, Erwin D, Brown J.

Psychooncology. 2019 Apr;28(4):888-895. doi: 10.1002/pon.5038. Epub 2019 Mar 18.

PMID:
30803084
35.

Fast Solver for Large Scale Multistate Bennett Acceptance Ratio Equations.

Ding X, Vilseck JZ, Brooks CL 3rd.

J Chem Theory Comput. 2019 Feb 12;15(2):799-802. doi: 10.1021/acs.jctc.8b01010. Epub 2019 Feb 4.

PMID:
30689377
36.

Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair.

Canaud G, Brooks CR, Kishi S, Taguchi K, Nishimura K, Magassa S, Scott A, Hsiao LL, Ichimura T, Terzi F, Yang L, Bonventre JV.

Sci Transl Med. 2019 Jan 23;11(476). pii: eaav4754. doi: 10.1126/scitranslmed.aav4754.

PMID:
30674655
37.

Fractured Tooth Stabilized with Auto Body Repair Resin on a 1970 Royal Navy Polaris Submarine Patrol.

Brooks CJ.

Aerosp Med Hum Perform. 2019 Feb 1;90(2):135-138. doi: 10.3357/AMHP.5208.2019.

PMID:
30670125
38.

Nursing and allied health professionals' views about using health literacy screening tools and a universal precautions approach to communication with older adults: a qualitative study.

Brooks C, Ballinger C, Nutbeam D, Mander C, Adams J.

Disabil Rehabil. 2019 Jan 22:1-7. doi: 10.1080/09638288.2018.1538392. [Epub ahead of print]

PMID:
30669896
39.

Update to Food and Drug Administration Regulation of Stroke Neurological Devices.

Peña C, Anderson L, Brooks C, Bydon M, Fusco M, Heetderks W, Herrmann R, Hoffmann M, Loftus C, Raben S, Seog J, Noonan P, Smith M, Williams D, Zheng X.

Stroke. 2019 Feb;50(2):524-528. doi: 10.1161/STROKEAHA.118.021078. No abstract available.

PMID:
30661499
40.

Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist.

Compton BJ, Farrand KJ, Tang CW, Osmond TL, Speir M, Authier-Hall A, Wang J, Ferguson PM, Chan STS, Anderson RJ, Cooney TR, Hayman CM, Williams GM, Brimble MA, Brooks CR, Yong LK, Metelitsa LS, Zajonc DM, Godfrey DI, Gasser O, Weinkove R, Painter GF, Hermans IF.

Org Biomol Chem. 2019 Jan 31;17(5):1225-1237. doi: 10.1039/c8ob02982b.

PMID:
30656346
41.

Chaperones and retinal disorders.

Sokolov M, Yadav RP, Brooks C, Artemyev NO.

Adv Protein Chem Struct Biol. 2019;114:85-117. doi: 10.1016/bs.apcsb.2018.09.001. Epub 2018 Nov 28.

PMID:
30635087
42.

H-NS uses an autoinhibitory conformational switch for environment-controlled gene silencing.

Shahul Hameed UF, Liao C, Radhakrishnan AK, Huser F, Aljedani SS, Zhao X, Momin AA, Melo FA, Guo X, Brooks C, Li Y, Cui X, Gao X, Ladbury JE, Jaremko Ł, Jaremko M, Li J, Arold ST.

Nucleic Acids Res. 2019 Mar 18;47(5):2666-2680. doi: 10.1093/nar/gky1299.

43.

Trends in Testosterone Prescribing for Age-related Hypogonadism in Men With and Without Heart Disease.

Morden NE, Woloshin S, Brooks CG, Schwartz LM.

JAMA Intern Med. 2019 Mar 1;179(3):446-448. doi: 10.1001/jamainternmed.2018.6505. No abstract available.

44.

Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.

Haji-Ghassemi O, Müller-Loennies S, Brooks CL, MacKenzie CR, Caveney N, Van Petegem F, Brade L, Kosma P, Brade H, Evans SV.

Biochemistry. 2019 Feb 12;58(6):714-726. doi: 10.1021/acs.biochem.8b00318. Epub 2019 Jan 10.

PMID:
30571096
45.

Analysis of Environmental Contaminants in Muskrat Root, Acorus americanus Raf.: A Traditional Indigenous Medicinal Plant.

Gray MA, Walker EM, Brooks C, deMarsh L.

Bull Environ Contam Toxicol. 2019 Feb;102(2):275-279. doi: 10.1007/s00128-018-2510-6. Epub 2018 Dec 14.

PMID:
30552440
46.

Room-temperature cycling of metal fluoride electrodes: Liquid electrolytes for high-energy fluoride ion cells.

Davis VK, Bates CM, Omichi K, Savoie BM, Momčilović N, Xu Q, Wolf WJ, Webb MA, Billings KJ, Chou NH, Alayoglu S, McKenney RK, Darolles IM, Nair NG, Hightower A, Rosenberg D, Ahmed M, Brooks CJ, Miller TF 3rd, Grubbs RH, Jones SC.

Science. 2018 Dec 7;362(6419):1144-1148. doi: 10.1126/science.aat7070.

PMID:
30523107
47.

Three-dimensional atomic scale electron density reconstruction of octahedral tilt epitaxy in functional perovskites.

Yuan Y, Lu Y, Stone G, Wang K, Brooks CM, Schlom DG, Sinnott SB, Zhou H, Gopalan V.

Nat Commun. 2018 Dec 6;9(1):5220. doi: 10.1038/s41467-018-07665-1.

48.

Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model.

Pero JE, Matthews JM, Behm DJ, Brnardic EJ, Brooks C, Budzik BW, Costell MH, Donatelli CA, Eisennagel SH, Erhard K, Fischer MC, Holt DA, Jolivette LJ, Li H, Li P, McAtee JJ, McCleland BW, Pendrak I, Posobiec LM, Rivera KLK, Rivero RA, Roethke TJ, Sender MR, Shu A, Terrell LR, Vaidya K, Xu X, Lawhorn BG.

J Med Chem. 2018 Dec 27;61(24):11209-11220. doi: 10.1021/acs.jmedchem.8b01344. Epub 2018 Dec 12.

PMID:
30500190
49.

Gabapentin Enacarbil Extended-Release for Alcohol Use Disorder: A Randomized, Double-Blind, Placebo-Controlled, Multisite Trial Assessing Efficacy and Safety.

Falk DE, Ryan ML, Fertig JB, Devine EG, Cruz R, Brown ES, Burns H, Salloum IM, Newport DJ, Mendelson J, Galloway G, Kampman K, Brooks C, Green AI, Brunette MF, Rosenthal RN, Dunn KE, Strain EC, Ray L, Shoptaw S, Ait-Daoud Tiouririne N, Gunderson EW, Ransom J, Scott C, Leggio L, Caras S, Mason BJ, Litten RZ; National Institute on Alcohol Abuse and Alcoholism Clinical Investigations Group (NCIG) Study Group.

Alcohol Clin Exp Res. 2019 Jan;43(1):158-169. doi: 10.1111/acer.13917. Epub 2018 Dec 9.

PMID:
30403402
50.

Investigating the Effect of Two-Point Surface Attachment on Enzyme Stability and Activity.

Zou X, Wei S, Badieyan S, Schroeder M, Jasensky J, Brooks CL 3rd, Marsh ENG, Chen Z.

J Am Chem Soc. 2018 Dec 5;140(48):16560-16569. doi: 10.1021/jacs.8b08138. Epub 2018 Nov 19.

PMID:
30403342

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