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Enrichment of cytomegalovirus-induced NKG2C+ Natural Killer cells in the lung allograft.

Harpur CM, Stankovic S, Kanagarajah A, Widjaja JML, Levvey BJ, Cristiano Y, Snell GI, Brooks AG, Westall GP, Sullivan LC.

Transplantation. 2018 Nov 19. doi: 10.1097/TP.0000000000002545. [Epub ahead of print]


Nightly Variation in Sleep Apnea Severity as Atrial Fibrillation Risk.

Linz D, Brooks AG, Elliott AD, Kalman JM, McEvoy RD, Lau DH, Sanders P.

J Am Coll Cardiol. 2018 Nov 6;72(19):2406-2407. doi: 10.1016/j.jacc.2018.08.2159. No abstract available.


Changes in Gut Microbiota Prior to Influenza A Virus Infection Do Not Affect Immune Responses in Pups or Juvenile Mice.

Fuglsang E, Pizzolla A, Krych L, Nielsen DS, Brooks AG, Frøkiær H, Reading PC.

Front Cell Infect Microbiol. 2018 Sep 12;8:319. doi: 10.3389/fcimb.2018.00319. eCollection 2018.


Diagnostic accuracy of overnight oximetry for the diagnosis of sleep-disordered breathing in atrial fibrillation patients.

Linz D, Kadhim K, Brooks AG, Elliott AD, Hendriks JML, Lau DH, Mahajan R, Gupta AK, Middeldorp ME, Hohl M, Nalliah CJ, Kalman JM, McEvoy RD, Baumert M, Sanders P.

Int J Cardiol. 2018 Dec 1;272:155-161. doi: 10.1016/j.ijcard.2018.07.124. Epub 2018 Jul 25.


Activating KIR Haplotype Influences Clinical Outcome Following HLA-Matched Sibling Hematopoietic Stem Cell Transplantation.

Heatley SL, Mullighan CG, Doherty K, Danner S, O'Connor GM, Hahn U, Szer J, Schwarer A, Bradstock K, Sullivan LC, Bardy PG, Brooks AG.

HLA. 2018 Jun 25. doi: 10.1111/tan.13327. [Epub ahead of print]


Oral Anticoagulation Therapy in Atrial Fibrillation Patients Managed in the Emergency Department Compared to Cardiology Outpatient: Opportunities for Improved Outcomes.

Rangnekar G, Gallagher C, Wong GR, Rocheleau S, Brooks AG, Hendriks JML, Middeldorp ME, Elliott AD, Mahajan R, Sanders P, Lau DH.

Heart Lung Circ. 2018 Apr 4. pii: S1443-9506(18)30140-9. doi: 10.1016/j.hlc.2018.03.024. [Epub ahead of print]


Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.

Martin MP, Naranbhai V, Shea PR, Qi Y, Ramsuran V, Vince N, Gao X, Thomas R, Brumme ZL, Carlson JM, Wolinsky SM, Goedert JJ, Walker BD, Segal FP, Deeks SG, Haas DW, Migueles SA, Connors M, Michael N, Fellay J, Gostick E, Llewellyn-Lacey S, Price DA, Lafont BA, Pymm P, Saunders PM, Widjaja J, Wong SC, Vivian JP, Rossjohn J, Brooks AG, Carrington M.

J Clin Invest. 2018 May 1;128(5):1903-1912. doi: 10.1172/JCI98463. Epub 2018 Apr 3.


Outcomes of persistent and long-standing persistent atrial fibrillation ablation: a systematic review and meta-analysis.

Clarnette JA, Brooks AG, Mahajan R, Elliott AD, Twomey DJ, Pathak RK, Kumar S, Munawar DA, Young GD, Kalman JM, Lau DH, Sanders P.

Europace. 2018 Nov 1;20(FI_3):f366-f376. doi: 10.1093/europace/eux297.


Host Cell Restriction Factors that Limit Influenza A Infection.

Villalón-Letelier F, Brooks AG, Saunders PM, Londrigan SL, Reading PC.

Viruses. 2017 Dec 7;9(12). pii: E376. doi: 10.3390/v9120376. Review.


A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors.

Sullivan LC, Walpole NG, Farenc C, Pietra G, Sum MJW, Clements CS, Lee EJ, Beddoe T, Falco M, Mingari MC, Moretta L, Gras S, Rossjohn J, Brooks AG.

J Biol Chem. 2017 Dec 22;292(51):21149-21158. doi: 10.1074/jbc.M117.807719. Epub 2017 Sep 25.


The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.

Mobbs JI, Illing PT, Dudek NL, Brooks AG, Baker DG, Purcell AW, Rossjohn J, Vivian JP.

J Biol Chem. 2017 Oct 20;292(42):17203-17215. doi: 10.1074/jbc.M117.806976. Epub 2017 Aug 30.


Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

Pizzolla A, Nguyen THO, Smith JM, Brooks AG, Kedzieska K, Heath WR, Reading PC, Wakim LM.

Sci Immunol. 2017 Jun 2;2(12). pii: eaam6970. doi: 10.1126/sciimmunol.aam6970.


Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells.

Pizzolla A, Wang Z, Groom JR, Kedzierska K, Brooks AG, Reading PC, Wakim LM.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):5225-5230. doi: 10.1073/pnas.1620194114. Epub 2017 May 1.


MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

Pymm P, Illing PT, Ramarathinam SH, O'Connor GM, Hughes VA, Hitchen C, Price DA, Ho BK, McVicar DW, Brooks AG, Purcell AW, Rossjohn J, Vivian JP.

Nat Struct Mol Biol. 2017 Apr;24(4):387-394. doi: 10.1038/nsmb.3381. Epub 2017 Feb 20.


Spatiotemporal characteristics of atrial fibrillation electrograms: A novel marker for arrhythmia stability and termination.

Thanigaimani S, Brooks AG, Kuklik P, Twomey DJ, Franklin S, Noschka E, Chapman D, Pathak RK, Mahajan R, Sanders P, Lau DH.

J Arrhythm. 2017 Feb;33(1):40-48. doi: 10.1016/j.joa.2016.05.009. Epub 2016 Jul 27.


Pattern recognition receptor immunomodulation of innate immunity as a strategy to limit the impact of influenza virus.

Pizzolla A, Smith JM, Brooks AG, Reading PC.

J Leukoc Biol. 2017 Apr;101(4):851-861. doi: 10.1189/jlb.4MR0716-290R. Epub 2016 Nov 3. Review.


Injuries Sustained by the Mixed Martial Arts Athlete.

Jensen AR, Maciel RC, Petrigliano FA, Rodriguez JP, Brooks AG.

Sports Health. 2017 Jan/Feb;9(1):64-69. doi: 10.1177/1941738116664860. Epub 2016 Aug 20.


Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.

Sullivan LC, Berry R, Sosnin N, Widjaja JM, Deuss FA, Balaji GR, LaGruta NL, Mirams M, Trapani JA, Rossjohn J, Brooks AG, Andrews DM.

J Biol Chem. 2016 Sep 2;291(36):18740-52. doi: 10.1074/jbc.M116.737130. Epub 2016 Jul 6.


DC-SIGN and L-SIGN Are Attachment Factors That Promote Infection of Target Cells by Human Metapneumovirus in the Presence or Absence of Cellular Glycosaminoglycans.

Gillespie L, Gerstenberg K, Ana-Sosa-Batiz F, Parsons MS, Farrukee R, Krabbe M, Spann K, Brooks AG, Londrigan SL, Reading PC.

J Virol. 2016 Aug 12;90(17):7848-63. doi: 10.1128/JVI.00537-16. Print 2016 Sep 1.


Neutralizing inhibitors in the airways of naïve ferrets do not play a major role in modulating the virulence of H3 subtype influenza A viruses.

Job ER, Pizzolla A, Nebl T, Short KR, Deng YM, Carolan L, Laurie KL, Brooks AG, Reading PC.

Virology. 2016 Jul;494:143-57. doi: 10.1016/j.virol.2016.01.024. Epub 2016 Apr 26.


Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition.

Saunders PM, Pymm P, Pietra G, Hughes VA, Hitchen C, O'Connor GM, Loiacono F, Widjaja J, Price DA, Falco M, Mingari MC, Moretta L, McVicar DW, Rossjohn J, Brooks AG, Vivian JP.

J Exp Med. 2016 May 2;213(5):791-807. doi: 10.1084/jem.20152023. Epub 2016 Apr 4.


Endocytic function is critical for influenza A virus infection via DC-SIGN and L-SIGN.

Gillespie L, Roosendahl P, Ng WC, Brooks AG, Reading PC, Londrigan SL.

Sci Rep. 2016 Jan 14;6:19428. doi: 10.1038/srep19428.


Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection.

Londrigan SL, Tate MD, Job ER, Moffat JM, Wakim LM, Gonelli CA, Purcell DF, Brooks AG, Villadangos JA, Reading PC, Mintern JD.

PLoS One. 2015 Nov 13;10(11):e0142925. doi: 10.1371/journal.pone.0142925. eCollection 2015.


The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus.

Ng WC, Londrigan SL, Nasr N, Cunningham AL, Turville S, Brooks AG, Reading PC.

J Virol. 2015 Oct 14;90(1):206-21. doi: 10.1128/JVI.01447-15. Print 2016 Jan 1.


Limited Internodal Migration of T Follicular Helper Cells after Peripheral Infection with Herpes Simplex Virus-1.

Stankovic S, Harpur CM, Macleod BL, Whitney PG, Gebhardt T, Brooks AG.

J Immunol. 2015 Nov 15;195(10):4892-9. doi: 10.4049/jimmunol.1500247. Epub 2015 Oct 9.


Infection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle.

Londrigan SL, Short KR, Ma J, Gillespie L, Rockman SP, Brooks AG, Reading PC.

J Virol. 2015 Dec;89(24):12319-29. doi: 10.1128/JVI.01455-15. Epub 2015 Sep 30.


The Presence of HLA-E-Restricted, CMV-Specific CD8+ T Cells in the Blood of Lung Transplant Recipients Correlates with Chronic Allograft Rejection.

Sullivan LC, Westall GP, Widjaja JM, Mifsud NA, Nguyen TH, Meehan AC, Kotsimbos TC, Brooks AG.

PLoS One. 2015 Aug 24;10(8):e0135972. doi: 10.1371/journal.pone.0135972. eCollection 2015.


Spatiotemporally Distinct Interactions with Dendritic Cell Subsets Facilitates CD4+ and CD8+ T Cell Activation to Localized Viral Infection.

Hor JL, Whitney PG, Zaid A, Brooks AG, Heath WR, Mueller SN.

Immunity. 2015 Sep 15;43(3):554-65. doi: 10.1016/j.immuni.2015.07.020. Epub 2015 Aug 18. Erratum in: Immunity. 2015 Sep 15;43(3):615.


A bird's eye view of NK cell receptor interactions with their MHC class I ligands.

Saunders PM, Vivian JP, O'Connor GM, Sullivan LC, Pymm P, Rossjohn J, Brooks AG.

Immunol Rev. 2015 Sep;267(1):148-66. doi: 10.1111/imr.12319. Review.


High-density mapping of atrial fibrillation in a chronic substrate: evidence for distinct modes of repetitive wavefront propagation.

Kuklik P, Lau DH, Ganesan AN, Brooks AG, Sanders P.

Int J Cardiol. 2015 Nov 15;199:407-14. doi: 10.1016/j.ijcard.2015.07.057. Epub 2015 Jul 30.


Electrophysiological, Electroanatomical, and Structural Remodeling of the Atria as Consequences of Sustained Obesity.

Mahajan R, Lau DH, Brooks AG, Shipp NJ, Manavis J, Wood JP, Finnie JW, Samuel CS, Royce SG, Twomey DJ, Thanigaimani S, Kalman JM, Sanders P.

J Am Coll Cardiol. 2015 Jul 7;66(1):1-11. doi: 10.1016/j.jacc.2015.04.058.


Erratum for O'Connor et al., Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

O'Connor GM, Vivian JP, Gostick E, Pymm P, Lafont BA, Price DA, Rossjohn J, Brooks AG, McVicar DW.

J Virol. 2015 Jul;89(14):7442. doi: 10.1128/JVI.01159-15. No abstract available.


Underuse and overuse of anticoagulation for atrial fibrillation: A study in Indigenous and non-Indigenous Australians.

Wong CX, Lee SW, Gan SW, Mahajan R, Rangnekar G, Pathak RK, Twomey D, Schultz C, Ganesan AN, Brooks AG, Roberts-Thomson KC, Brown A, Lau DH, Sanders P.

Int J Cardiol. 2015 Jul 15;191:20-4. doi: 10.1016/j.ijcard.2015.03.064. Epub 2015 Mar 4.


The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.

Moradi S, Berry R, Pymm P, Hitchen C, Beckham SA, Wilce MC, Walpole NG, Clements CS, Reid HH, Perugini MA, Brooks AG, Rossjohn J, Vivian JP.

J Biol Chem. 2015 Apr 17;290(16):10460-71. doi: 10.1074/jbc.M114.612291. Epub 2015 Mar 10.


Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

O'Connor GM, Vivian JP, Gostick E, Pymm P, Lafont BA, Price DA, Rossjohn J, Brooks AG, McVicar DW.

J Virol. 2015 May;89(10):5213-21. doi: 10.1128/JVI.03586-14. Epub 2015 Mar 4. Erratum in: J Virol. 2015 Jul;89(14):7442.


Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines.

Caccamo N, Pietra G, Sullivan LC, Brooks AG, Prezzemolo T, La Manna MP, Di Liberto D, Joosten SA, van Meijgaarden KE, Di Carlo P, Titone L, Moretta L, Mingari MC, Ottenhoff TH, Dieli F.

Eur J Immunol. 2015 Apr;45(4):1069-81. doi: 10.1002/eji.201445193. Epub 2015 Feb 17.


Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates.

Li J, Ahmet F, Sullivan LC, Brooks AG, Kent SJ, De Rose R, Salazar AM, Reis e Sousa C, Shortman K, Lahoud MH, Heath WR, Caminschi I.

Eur J Immunol. 2015 Mar;45(3):854-64. doi: 10.1002/eji.201445127. Epub 2015 Jan 14.


The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope.

Saunders PM, Vivian JP, Baschuk N, Beddoe T, Widjaja J, O'Connor GM, Hitchen C, Pymm P, Andrews DM, Gras S, McVicar DW, Rossjohn J, Brooks AG.

J Immunol. 2015 Jan 15;194(2):781-789. doi: 10.4049/jimmunol.1402542. Epub 2014 Dec 5.


Atrial fibrillation in Indigenous and non-Indigenous Australians: a cross-sectional study.

Wong CX, Brooks AG, Cheng YH, Lau DH, Rangnekar G, Roberts-Thomson KC, Kalman JM, Brown A, Sanders P.

BMJ Open. 2014 Oct 24;4(10):e006242. doi: 10.1136/bmjopen-2014-006242.


Distinct APC subtypes drive spatially segregated CD4+ and CD8+ T-cell effector activity during skin infection with HSV-1.

Macleod BL, Bedoui S, Hor JL, Mueller SN, Russell TA, Hollett NA, Heath WR, Tscharke DC, Brooks AG, Gebhardt T.

PLoS Pathog. 2014 Aug 14;10(8):e1004303. doi: 10.1371/journal.ppat.1004303. eCollection 2014 Aug.


Development of a surgical skills curriculum for the training and assessment of manual skills in orthopedic surgical residents.

Hohn EA, Brooks AG, Leasure J, Camisa W, van Warmerdam J, Kondrashov D, Montgomery W, McGann W.

J Surg Educ. 2015 Jan-Feb;72(1):47-52. doi: 10.1016/j.jsurg.2014.06.005. Epub 2014 Aug 6.


The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins.

Berry R, Vivian JP, Deuss FA, Balaji GR, Saunders PM, Lin J, Littler DR, Brooks AG, Rossjohn J.

J Biol Chem. 2014 Aug 22;289(34):23753-63. doi: 10.1074/jbc.M114.584128. Epub 2014 Jun 30.


Quantitative description of the 3D regional mechanics of the left atrium using cardiac magnetic resonance imaging.

Kuklik P, Molaee P, Podziemski P, Ganesan AN, Brooks AG, Worthley SG, Sanders P.

Physiol Meas. 2014 May;35(5):763-75. doi: 10.1088/0967-3334/35/5/763. Epub 2014 Mar 26.


Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity.

O'Connor GM, Vivian JP, Widjaja JM, Bridgeman JS, Gostick E, Lafont BA, Anderson SK, Price DA, Brooks AG, Rossjohn J, McVicar DW.

J Immunol. 2014 Mar 15;192(6):2875-84. doi: 10.4049/jimmunol.1303142. Epub 2014 Feb 21.


Cardiovascular magnetic resonance of total and atrial pericardial adipose tissue: a validation study and development of a 3 dimensional pericardial adipose tissue model.

Mahajan R, Kuklik P, Grover S, Brooks AG, Wong CX, Sanders P, Selvanayagam JB.

J Cardiovasc Magn Reson. 2013 Aug 29;15:73. doi: 10.1186/1532-429X-15-73.


Time course of inflammation, myocardial injury, and prothrombotic response after radiofrequency catheter ablation for atrial fibrillation.

Lim HS, Schultz C, Dang J, Alasady M, Lau DH, Brooks AG, Wong CX, Roberts-Thomson KC, Young GD, Worthley MI, Sanders P, Willoughby SR.

Circ Arrhythm Electrophysiol. 2014 Feb;7(1):83-9. doi: 10.1161/CIRCEP.113.000876. Epub 2014 Jan 20.


The Ly49 natural killer cell receptors: a versatile tool for viral self-discrimination.

Berry R, Rossjohn J, Brooks AG.

Immunol Cell Biol. 2014 Mar;92(3):214-20. doi: 10.1038/icb.2013.100. Epub 2014 Jan 14. Review.


High-density mapping of ventricular scar: a comparison of ventricular tachycardia (VT) supporting channels with channels that do not support VT.

Nayyar S, Wilson L, Ganesan AN, Sullivan T, Kuklik P, Chapman D, Brooks AG, Mahajan R, Baumert M, Young GD, Sanders P, Roberts-Thomson KC.

Circ Arrhythm Electrophysiol. 2014 Feb;7(1):90-8. doi: 10.1161/CIRCEP.113.000882. Epub 2014 Jan 1.


Anti-HIV antibody-dependent activation of NK cells impairs NKp46 expression.

Parsons MS, Tang CC, Jegaskanda S, Center RJ, Brooks AG, Stratov I, Kent SJ.

J Immunol. 2014 Jan 1;192(1):308-15. doi: 10.4049/jimmunol.1301247. Epub 2013 Dec 6.


A single amino acid substitution in the hemagglutinin of H3N2 subtype influenza A viruses is associated with resistance to the long pentraxin PTX3 and enhanced virulence in mice.

Job ER, Bottazzi B, Short KR, Deng YM, Mantovani A, Brooks AG, Reading PC.

J Immunol. 2014 Jan 1;192(1):271-81. doi: 10.4049/jimmunol.1301814. Epub 2013 Dec 4.

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