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Items: 4

1.

Seletalisib: Characterization of a Novel, Potent, and Selective Inhibitor of PI3Kδ.

Allen RA, Brookings DC, Powell MJ, Delgado J, Shuttleworth LK, Merriman M, Fahy IJ, Tewari R, Silva JP, Healy LJ, Davies GCG, Twomey B, Cutler RM, Kotian A, Crosby A, McCluskey G, Watt GF, Payne A.

J Pharmacol Exp Ther. 2017 Jun;361(3):429-440. doi: 10.1124/jpet.116.237347. Epub 2017 Apr 25.

PMID:
28442583
2.

Engineering human MEK-1 for structural studies: A case study of combinatorial domain hunting.

Meier C, Brookings DC, Ceska TA, Doyle C, Gong H, McMillan D, Saville GP, Mushtaq A, Knight D, Reich S, Pearl LH, Powell KA, Savva R, Allen RA.

J Struct Biol. 2012 Feb;177(2):329-34. doi: 10.1016/j.jsb.2012.01.002. Epub 2012 Jan 8.

PMID:
22245778
3.

Fused thiophene derivatives as MEK inhibitors.

Laing VE, Brookings DC, Carbery RJ, Simorte JG, Hutchings MC, Langham BJ, Lowe MA, Allen RA, Fetterman JR, Turner J, Meier C, Kennedy J, Merriman M.

Bioorg Med Chem Lett. 2012 Jan 1;22(1):472-5. doi: 10.1016/j.bmcl.2011.10.105. Epub 2011 Nov 6.

PMID:
22119475
4.

Peptide deformylase inhibitors with activity against respiratory tract pathogens.

East SP, Beckett RP, Brookings DC, Clements JM, Doel S, Keavey K, Pain G, Smith HK, Thomas W, Thompson AJ, Todd RS, Whittaker M.

Bioorg Med Chem Lett. 2004 Jan 5;14(1):59-62.

PMID:
14684298

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