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Items: 1 to 50 of 110

1.

A Framework for Effective Promotion of a Medicaid Tobacco Cessation Benefit.

Williams RK, Brookes RL, Singer ER.

Health Promot Pract. 2019 Feb 20:1524839919829452. doi: 10.1177/1524839919829452. [Epub ahead of print]

PMID:
30786777
2.

Apathy is associated with large-scale white matter network disruption in small vessel disease.

Tay J, Tuladhar AM, Hollocks MJ, Brookes RL, Tozer DJ, Barrick TR, Husain M, de Leeuw FE, Markus HS.

Neurology. 2019 Mar 12;92(11):e1157-e1167. doi: 10.1212/WNL.0000000000007095. Epub 2019 Feb 8.

3.

Framingham vascular age is associated with worse cognitive performance in the middle-aged and elderly.

Badran A, Hollocks MJ, Brookes RL, Morris RG, Markus HS.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2019 Jul;26(4):531-540. doi: 10.1080/13825585.2018.1499866. Epub 2018 Jul 27.

PMID:
30053789
4.

Sodium Valproate, a Histone Deacetylase Inhibitor, Is Associated With Reduced Stroke Risk After Previous Ischemic Stroke or Transient Ischemic Attack.

Brookes RL, Crichton S, Wolfe CDA, Yi Q, Li L, Hankey GJ, Rothwell PM, Markus HS.

Stroke. 2018 Jan;49(1):54-61. doi: 10.1161/STROKEAHA.117.016674. Epub 2017 Dec 15.

5.

Change in multimodal MRI markers predicts dementia risk in cerebral small vessel disease.

Zeestraten EA, Lawrence AJ, Lambert C, Benjamin P, Brookes RL, Mackinnon AD, Morris RG, Barrick TR, Markus HS.

Neurology. 2017 Oct 31;89(18):1869-1876. doi: 10.1212/WNL.0000000000004594. Epub 2017 Oct 4.

6.

The Brief Memory and Executive Test (BMET): A cognitive screening tool to detect and differentiate vascular cognitive impairment and Alzheimer's disease.

Hollocks MJ, Brookes RL, Morris RG, Markus HS.

Int J Geriatr Psychiatry. 2018 Feb;33(2):e273-e279. doi: 10.1002/gps.4787. Epub 2017 Sep 7.

PMID:
28881062
7.

Mnemonic function in small vessel disease and associations with white matter tract microstructure.

Metoki A, Brookes RL, Zeestraten E, Lawrence AJ, Morris RG, Barrick TR, Markus HS, Charlton RA.

Neuropsychologia. 2017 Sep;104:1-7. doi: 10.1016/j.neuropsychologia.2017.07.027. Epub 2017 Jul 24.

8.

Mycobacterium tuberculosis Infection in Close Childhood Contacts of Adults with Pulmonary Tuberculosis is Increased by Secondhand Exposure to Tobacco.

Adetifa IMO, Kendall L, Donkor S, Lugos MD, Hammond AS, Owiafe PK, Ota MOC, Brookes RH, Hill PC.

Am J Trop Med Hyg. 2017 Aug;97(2):429-432. doi: 10.4269/ajtmh.16-0611. Epub 2017 Jul 19.

9.

An adjuvant-modulated vaccine response in human whole blood.

Hakimi J, Azizi A, Ausar SF, Todryk SM, Rahman N, Brookes RH.

Hum Vaccin Immunother. 2017 Sep 2;13(9):2130-2134. doi: 10.1080/21645515.2017.1337616. Epub 2017 Jun 12.

10.

Apathy, but not depression, is associated with executive dysfunction in cerebral small vessel disease.

Lohner V, Brookes RL, Hollocks MJ, Morris RG, Markus HS.

PLoS One. 2017 May 11;12(5):e0176943. doi: 10.1371/journal.pone.0176943. eCollection 2017.

11.

Screening Vaccine Formulations in Fresh Human Whole Blood.

Hakimi J, Aboutorabian S, To F, Ausar SF, Rahman N, Brookes RH.

Methods Mol Biol. 2017;1494:295-304.

PMID:
27718203
12.

Brief Screening of Vascular Cognitive Impairment in Patients With Cerebral Autosomal-Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Without Dementia.

Brookes RL, Hollocks MJ, Tan RY, Morris RG, Markus HS.

Stroke. 2016 Oct;47(10):2482-7. doi: 10.1161/STROKEAHA.116.013761. Epub 2016 Sep 13.

13.

A bivalent pneumococcal histidine triad protein D-choline-binding protein A vaccine elicits functional antibodies that passively protect mice from Streptococcus pneumoniae challenge.

Ochs MM, Williams K, Sheung A, Lheritier P, Visan L, Rouleau N, Proust E, de Montfort A, Tang M, Mari K, Hopfer R, Gallichan S, Brookes RH.

Hum Vaccin Immunother. 2016 Nov;12(11):2946-2952.

14.

Associations between the Brief Memory and Executive Test (BMET), Activities of Daily Living, and Quality of Life in Patients with Cerebral Small Vessel Disease.

Hollocks MJ, Brookes R, Morris RG, Markus HS.

J Int Neuropsychol Soc. 2016 May;22(5):561-9. doi: 10.1017/S1355617716000187. Epub 2016 Apr 6.

PMID:
27048925
15.

Differential relationships between apathy and depression with white matter microstructural changes and functional outcomes.

Hollocks MJ, Lawrence AJ, Brookes RL, Barrick TR, Morris RG, Husain M, Markus HS.

Brain. 2015 Dec;138(Pt 12):3803-15. doi: 10.1093/brain/awv304. Epub 2015 Oct 21.

16.

Pattern and Rate of Cognitive Decline in Cerebral Small Vessel Disease: A Prospective Study.

Lawrence AJ, Brookes RL, Zeestraten EA, Barrick TR, Morris RG, Markus HS.

PLoS One. 2015 Aug 14;10(8):e0135523. doi: 10.1371/journal.pone.0135523. eCollection 2015.

17.

A high ratio of IC31(®) adjuvant to antigen is necessary for H4 TB vaccine immunomodulation.

Aboutorabian S, Hakimi J, Boudet F, Montano S, Dookie A, Roque C, Ausar SF, Rahman N, Brookes RH.

Hum Vaccin Immunother. 2015;11(6):1449-55. doi: 10.1080/21645515.2015.1023970.

18.

Passive protection of mice against Streptococcus pneumoniae challenge by naturally occurring and vaccine-induced human anti-PhtD antibodies.

Brookes RH, Ming M, Williams K, Hopfer R, Gurunathan S, Gallichan S, Tang M, Ochs MM.

Hum Vaccin Immunother. 2015;11(7):1836-9. doi: 10.1080/21645515.2015.1039210.

19.

The Brief Memory and Executive Test (BMET) for detecting vascular cognitive impairment in small vessel disease: a validation study.

Brookes RL, Hollocks MJ, Khan U, Morris RG, Markus HS.

BMC Med. 2015 Mar 11;13:51. doi: 10.1186/s12916-015-0290-y.

20.

Depression in small-vessel disease relates to white matter ultrastructural damage, not disability.

Brookes RL, Herbert V, Lawrence AJ, Morris RG, Markus HS.

Neurology. 2014 Oct 14;83(16):1417-23. doi: 10.1212/WNL.0000000000000882. Epub 2014 Sep 17.

21.

Verbal fluency in cerebral small vessel disease and Alzheimer's disease.

Herbert V, Brookes RL, Markus HS, Morris RG.

J Int Neuropsychol Soc. 2014 Apr;20(4):413-21. doi: 10.1017/S1355617714000101. Epub 2014 Mar 3.

PMID:
24589176
22.

Screening vaccine formulations for biological activity using fresh human whole blood.

Brookes RH, Hakimi J, Ha Y, Aboutorabian S, Ausar SF, Hasija M, Smith SG, Todryk SM, Dockrell HM, Rahman N.

Hum Vaccin Immunother. 2014;10(4):1129-35. Epub 2014 Jan 8.

23.

Improving the management of patients with acute red eyes in a large London Emergency Department.

Saifuddin A, Brookes R.

BMJ Qual Improv Rep. 2014 Jun 13;3(1). pii: u201656.w1962. doi: 10.1136/bmjquality.u201656.w1962. eCollection 2014.

24.

Executive dysfunction, awareness deficits and quality of life in patients with cerebral small vessel disease: a structural equation model.

Brookes RL, Herbert V, Paul S, Hannesdottir K, Markus HS, Morris RG.

Neuropsychology. 2014 Mar;28(2):247-253. doi: 10.1037/neu0000015. Epub 2013 Nov 25.

PMID:
24274025
25.

Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR.

Rottiers V, Obad S, Petri A, McGarrah R, Lindholm MW, Black JC, Sinha S, Goody RJ, Lawrence MS, deLemos AS, Hansen HF, Whittaker S, Henry S, Brookes R, Najafi-Shoushtari SH, Chung RT, Whetstine JR, Gerszten RE, Kauppinen S, Näär AM.

Sci Transl Med. 2013 Nov 20;5(212):212ra162. doi: 10.1126/scitranslmed.3006840.

26.

Elevated inflammatory markers combined with positive pneumococcal urinary antigen are a good predictor of pneumococcal community-acquired pneumonia in children.

Galetto-Lacour A, Alcoba G, Posfay-Barbe KM, Cevey-Macherel M, Gehri M, Ochs MM, Brookes RH, Siegrist CA, Gervaix A.

Pediatr Infect Dis J. 2013 Nov;32(11):1175-9. doi: 10.1097/INF.0b013e31829ba62a.

PMID:
23694836
27.

Interferon-γ ELISPOT as a biomarker of treatment efficacy in latent tuberculosis infection: a clinical trial.

Adetifa IM, Ota MO, Jeffries DJ, Lugos MD, Hammond AS, Battersby NJ, Owiafe PK, Donkor SD, Antonio M, Ibanga HB, Brookes RH, Aka P, Walton R, Adegbola RA, Hill PC.

Am J Respir Crit Care Med. 2013 Feb 15;187(4):439-45. doi: 10.1164/rccm.201208-1352OC. Epub 2012 Dec 6.

PMID:
23220919
28.

Safety and immunogenicity of a pneumococcal histidine triad protein D vaccine candidate in adults.

Seiberling M, Bologa M, Brookes R, Ochs M, Go K, Neveu D, Kamtchoua T, Lashley P, Yuan T, Gurunathan S.

Vaccine. 2012 Dec 14;30(52):7455-60. doi: 10.1016/j.vaccine.2012.10.080. Epub 2012 Nov 3.

PMID:
23131206
29.

Influence of age, social patterns and nasopharyngeal carriage on antibodies to three conserved pneumococcal surface proteins (PhtD, PcpA and PrtA) in healthy young children.

Hagerman A, Posfay-Barbe KM, Grillet S, Ochs MM, Brookes RH, Greenberg D, Givon-Lavi N, Dagan R, Siegrist CA.

Eur J Clin Microbiol Infect Dis. 2013 Jan;32(1):43-9. doi: 10.1007/s10096-012-1712-9. Epub 2012 Aug 18.

PMID:
22903166
30.

Synthetic collagen fascicles for the regeneration of tendon tissue.

Kew SJ, Gwynne JH, Enea D, Brookes R, Rushton N, Best SM, Cameron RE.

Acta Biomater. 2012 Oct;8(10):3723-31. doi: 10.1016/j.actbio.2012.06.018. Epub 2012 Jun 21.

PMID:
22728568
31.

Lack of awareness of neuropsychological deficit in cerebral small vessel disease: the relationship with executive and episodic memory functions.

Brookes RL, Hannesdottir K, Markus HS, Morris RG.

J Neuropsychol. 2013 Mar;7(1):19-28. doi: 10.1111/j.1748-6653.2012.02032.x. Epub 2012 Jun 14.

PMID:
22697174
32.

Depressive symptoms as a predictor of quality of life in cerebral small vessel disease, acting independently of disability; a study in both sporadic small vessel disease and CADASIL.

Brookes RL, Willis TA, Patel B, Morris RG, Markus HS.

Int J Stroke. 2013 Oct;8(7):510-7. doi: 10.1111/j.1747-4949.2011.00763.x. Epub 2012 Feb 26.

33.

Brief Memory and Executive Test: evaluation of a new screening test for cognitive impairment due to small vessel disease.

Brookes RL, Hannesdottir K, Lawrence R, Morris RG, Markus HS.

Age Ageing. 2012 Mar;41(2):212-8. doi: 10.1093/ageing/afr172. Epub 2012 Jan 19.

34.

Failure to elicit seroresponses to pneumococcal surface proteins (pneumococcal histidine triad D, pneumococcal choline-binding protein A, and serine proteinase precursor A) in children with pneumococcal bacteraemia.

Hagerman A, Posfay-Barbe KM, Grillet S, Ochs MM, Brookes RH, Greenberg D, Givon-Lavi N, Dagan R, Siegrist CA.

Clin Microbiol Infect. 2012 Aug;18(8):756-62. doi: 10.1111/j.1469-0691.2011.03629.x. Epub 2011 Aug 18.

35.

Immunity to pneumococcal surface proteins in children with community-acquired pneumonia: a distinct pattern of responses to pneumococcal choline-binding protein A.

Posfay-Barbe KM, Galetto-Lacour A, Grillet S, Ochs MM, Brookes RH, Kraehenbuhl JD, Cevey-Macherel M, Gehri M, Gervaix A, Siegrist CA.

Clin Microbiol Infect. 2011 Aug;17(8):1232-8. doi: 10.1111/j.1469-0691.2010.03389.x. Epub 2010 Dec 17.

36.

Striking the right balance: motor difficulties in children and adults with dyslexia.

Brookes RL, Tinkler S, Nicolson RI, Fawcett AJ.

Dyslexia. 2010 Nov;16(4):358-73. doi: 10.1002/dys.420.

PMID:
20957688
37.

Procedural learning and dyslexia.

Nicolson RI, Fawcett AJ, Brookes RL, Needle J.

Dyslexia. 2010 Aug;16(3):194-212. doi: 10.1002/dys.408. Review.

PMID:
20680991
38.

Reproductive investment within inflorescences of Stylidium armeria varies with the strength of early resource commitment.

Brookes RH, Jesson LK, Burd M.

Ann Bot. 2010 May;105(5):697-705. doi: 10.1093/aob/mcq026. Epub 2010 Apr 7.

39.

A test of simultaneous resource and pollen limitation in Stylidium armeria.

Brookes RH, Jesson LK, Burd M.

New Phytol. 2008 Jul;179(2):557-65. doi: 10.1111/j.1469-8137.2008.02453.x.

40.

Safety and immunogenicity of the candidate tuberculosis vaccine MVA85A in West Africa.

Brookes RH, Hill PC, Owiafe PK, Ibanga HB, Jeffries DJ, Donkor SA, Fletcher HA, Hammond AS, Lienhardt C, Adegbola RA, McShane H, Hill AV.

PLoS One. 2008 Aug 13;3(8):e2921. doi: 10.1371/journal.pone.0002921. Erratum in: PLoS One. 2011;6(2). doi:10.1371/annotation/5284a0b6-62a9-484e-80a4-a08c59b3b17c.

41.

Characterization of Melan-A reactive memory CD8+ T cells in a healthy donor.

Voelter V, Rufer N, Reynard S, Greub G, Brookes R, Guillaume P, Grosjean F, Fagerberg T, Michelin O, Rowland-Jones S, Pinilla C, Leyvraz S, Romero P, Appay V.

Int Immunol. 2008 Aug;20(8):1087-96. doi: 10.1093/intimm/dxn066. Epub 2008 Jun 23.

PMID:
18573812
42.

Mycobacterial T cell responses in HIV-infected patients with advanced immunosuppression.

Hammond AS, McConkey SJ, Hill PC, Crozier S, Klein MR, Adegbola RA, Rowland-Jones S, Brookes RH, Whittle H, Jaye A.

J Infect Dis. 2008 Jan 15;197(2):295-9. doi: 10.1086/524685.

PMID:
18194089
43.

Incidence of tuberculosis and the predictive value of ELISPOT and Mantoux tests in Gambian case contacts.

Hill PC, Jackson-Sillah DJ, Fox A, Brookes RH, de Jong BC, Lugos MD, Adetifa IM, Donkor SA, Aiken AM, Howie SR, Corrah T, McAdam KP, Adegbola RA.

PLoS One. 2008 Jan 2;3(1):e1379. doi: 10.1371/journal.pone.0001379.

44.

The effect of tuberculin skin test and BCG vaccination on the expansion of PPD-specific IFN-gamma producing cells ex vivo.

Ota MO, Brookes RH, Hill PC, Owiafe PK, Ibanga HB, Donkor S, Awine T, McShane H, Adegbola RA.

Vaccine. 2007 Dec 17;25(52):8861-7. Epub 2007 Oct 31.

PMID:
18023944
45.

Longitudinal assessment of an ELISPOT test for Mycobacterium tuberculosis infection.

Hill PC, Brookes RH, Fox A, Jackson-Sillah D, Jeffries DJ, Lugos MD, Donkor SA, Adetifa IM, de Jong BC, Aiken AM, Adegbola RA, McAdam KP.

PLoS Med. 2007 Jun;4(6):e192.

46.

FOXP3 gene expression in a tuberculosis case contact study.

Burl S, Hill PC, Jeffries DJ, Holland MJ, Fox A, Lugos MD, Adegbola RA, Rook GA, Zumla A, McAdam KP, Brookes RH.

Clin Exp Immunol. 2007 Jul;149(1):117-22. Epub 2007 Apr 26.

47.

Extended culture enhances sensitivity of a gamma interferon assay for latent Mycobacterium tuberculosis infection.

Cehovin A, Cliff JM, Hill PC, Brookes RH, Dockrell HM.

Clin Vaccine Immunol. 2007 Jun;14(6):796-8. Epub 2007 Apr 25.

48.

ESAT-6 and CFP-10 can be combined to reduce the cost of testing for Mycobacterium tuberculosis infection, but CFP-10 responses associate with active disease.

Fox A, Jeffries DJ, Hill PC, Hammond AS, Lugos MD, Jackson-Sillah D, Donkor SA, Owiafe PK, McAdam KP, Brookes RH.

Trans R Soc Trop Med Hyg. 2007 Jul;101(7):691-8. Epub 2007 Apr 16.

PMID:
17434194
49.

Screening for tuberculosis among 2381 household contacts of sputum-smear-positive cases in The Gambia.

Jackson-Sillah D, Hill PC, Fox A, Brookes RH, Donkor SA, Lugos MD, Howie SR, Fielding KR, Jallow A, Lienhardt C, Corrah T, Adegbola RA, McAdam KP.

Trans R Soc Trop Med Hyg. 2007 Jun;101(6):594-601. Epub 2007 Mar 26.

PMID:
17368495
50.

Rising ELISPOT count prior to the onset of symptoms of full-blown tuberculosis disease.

Adetifa IM, Brookes R, Lugos MD, de Jong BC, Antonio M, Adegbola RA, Hill PC.

Int J Tuberc Lung Dis. 2007 Mar;11(3):350-2.

PMID:
17352104

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