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ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation) randomised controlled, feasibility in older people trial: a study protocol.

van Berkel D, Ong T, Drummond A, Hendrick P, Leighton P, Jones M, Salem K, Quraishi N, Brookes C, Suazo Di Paola A, Edwards S, Sahota O.

BMJ Open. 2019 Jul 10;9(7):e032111. doi: 10.1136/bmjopen-2019-032111.


Desmoplastic fibroma associated with tuberous sclerosis: case report and literature review.

Fahmy MD, Gupta A, Padilla RJ, Segura A, Brookes CD.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Aug;128(2):e92-e99. doi: 10.1016/j.oooo.2019.03.008. Epub 2019 Mar 16. Review.


Pathway-based subnetworks enable cross-disease biomarker discovery.

Haider S, Yao CQ, Sabine VS, Grzadkowski M, Stimper V, Starmans MHW, Wang J, Nguyen F, Moon NC, Lin X, Drake C, Crozier CA, Brookes CL, van de Velde CJH, Hasenburg A, Kieback DG, Markopoulos CJ, Dirix LY, Seynaeve C, Rea DW, Kasprzyk A, Lambin P, Lio' P, Bartlett JMS, Boutros PC.

Nat Commun. 2018 Nov 12;9(1):4746. doi: 10.1038/s41467-018-07021-3.


Effect of sildenafil (Revatio) on postcardiac surgery acute kidney injury: a randomised, placebo-controlled clinical trial: the REVAKI-2 trial protocol.

Aujla H, Kumar T, Woźniak M, Dott W, Sullo N, Joel-David L, Morris T, Brookes C, Barber S, Murphy GJ.

Open Heart. 2018 Oct 18;5(2):e000838. doi: 10.1136/openhrt-2018-000838. eCollection 2018.


Influence of Graft Source on Postoperative Activity and Joint Laxity in Posterior Cruciate Ligament Reconstruction: A Systematic Review.

Ansari AS, Dennis BB, Horner NS, Zhu M, Brookes C, Khan M, Grant JA.

Arthroscopy. 2019 Jan;35(1):262-274.e6. doi: 10.1016/j.arthro.2018.07.027. Epub 2018 Oct 5. Review.


Human TANK-binding kinase 1 is required for early autophagy induction upon herpes simplex virus 1 infection.

Ahmad L, Mashbat B, Leung C, Brookes C, Hamad S, Krokowski S, Shenoy AR, Lorenzo L, Levin M, O'Hare P, Zhang SY, Casanova JL, Mostowy S, Sancho-Shimizu V.

J Allergy Clin Immunol. 2019 Feb;143(2):765-769.e7. doi: 10.1016/j.jaci.2018.09.013. Epub 2018 Oct 5. No abstract available.


Bordetella pertussis isolates vary in their interactions with human complement components.

Brookes C, Freire-Martin I, Cavell B, Alexander F, Taylor S, Persaud R, Fry N, Preston A, Diavatopoulos D, Gorringe A.

Emerg Microbes Infect. 2018 May 9;7(1):81. doi: 10.1038/s41426-018-0084-3.


Confusion Over Differences in Registration and Randomization Criteria for the LORIS (Low-Risk DCIS) Trial.

Rea D, Francis A, Wallis M, Thomas J, Bartlett J, Bowden S, Dodwell D, Fallowfield L, Gaunt C, Hanby A, Jenkins V, Matthews L, Pinder S, Pirrie S, Reed M, Wilcox M, Roberts T, Kirwan C, Brookes C, Fairbrother P, Billingham L, Evans A, Young J.

Ann Surg Oncol. 2017 Dec;24(Suppl 3):566-567. doi: 10.1245/s10434-017-6174-y. Epub 2017 Nov 28. No abstract available.


Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine.

Bayani J, Yao CQ, Quintayo MA, Yan F, Haider S, D'Costa A, Brookes CL, van de Velde CJH, Hasenburg A, Kieback DG, Markopoulos C, Dirix L, Seynaeve C, Rea D, Boutros PC, Bartlett JMS.

NPJ Breast Cancer. 2017 Feb 15;3:3. doi: 10.1038/s41523-016-0003-5. eCollection 2017.


HER2 status predicts for upfront AI benefit: A TRANS-AIOG meta-analysis of 12,129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2.

Bartlett JMS, Ahmed I, Regan MM, Sestak I, Mallon EA, Dell'Orto P, Thürlimann B, Seynaeve C, Putter H, Van de Velde CJH, Brookes CL, Forbes JF, Viale G, Cuzick J, Dowsett M, Rea DW; Translational Aromatase Inhibitor Overview Group (Trans-AIOG).

Eur J Cancer. 2017 Jul;79:129-138. doi: 10.1016/j.ejca.2017.03.033. Epub 2017 May 8.


Toward a public health approach to the protection of vulnerable populations from the harmful effects of alcohol marketing.

Babor TF, Jernigan D, Brookes C, Brown K.

Addiction. 2017 Jan;112 Suppl 1:125-127. doi: 10.1111/add.13682. Review. No abstract available.


Alcohol marketing regulation: from research to public policy.

Monteiro MG, Babor TF, Jernigan D, Brookes C.

Addiction. 2017 Jan;112 Suppl 1:3-6. doi: 10.1111/add.13660. No abstract available.


International codes and agreements to restrict the promotion of harmful products can hold lessons for the control of alcohol marketing.

Landon J, Lobstein T, Godfrey F, Johns P, Brookes C, Jernigan D.

Addiction. 2017 Jan;112 Suppl 1:102-108. doi: 10.1111/add.13545. Epub 2016 Oct 18. Review.


Clinical Experience of Prescribing Dabigatran Etexilate With Dronedarone: The Role of Therapeutic Drug Monitoring.

Lock J, Patel RK, Brookes C, Patel JP.

Ther Drug Monit. 2016 Dec;38(6):813-814. No abstract available.


Individual placement and support (IPS) for patients with offending histories: the IPSOH feasibility cluster randomised trial protocol.

Khalifa N, Talbot E, Schneider J, Walker DM, Bates P, Bird Y, Davies D, Brookes C, Hall J, Völlm B.

BMJ Open. 2016 Jul 22;6(7):e012710. doi: 10.1136/bmjopen-2016-012710.


Methanol oxidation on Fe2O3 catalysts and the effects of surface Mo.

Bowker M, Gibson EK, Silverwood IP, Brookes C.

Faraday Discuss. 2016 Jul 4;188:387-98. doi: 10.1039/c5fd00225g.


Design and stabilisation of a high area iron molybdate surface for the selective oxidation of methanol to formaldehyde.

Chapman S, Brookes C, Bowker M, Gibson EK, Wells PP.

Faraday Discuss. 2016 Jul 4;188:115-29. doi: 10.1039/c5fd00153f.


Orbital apex disorders: a case series.

Warburton RE, Brookes CC, Golden BA, Turvey TA.

Int J Oral Maxillofac Surg. 2016 Apr;45(4):497-506. doi: 10.1016/j.ijom.2015.10.014. Epub 2015 Dec 24.


Addressing overtreatment of screen detected DCIS; the LORIS trial.

Francis A, Thomas J, Fallowfield L, Wallis M, Bartlett JM, Brookes C, Roberts T, Pirrie S, Gaunt C, Young J, Billingham L, Dodwell D, Hanby A, Pinder SE, Evans A, Reed M, Jenkins V, Matthews L, Wilcox M, Fairbrother P, Bowden S, Rea D.

Eur J Cancer. 2015 Nov;51(16):2296-303. doi: 10.1016/j.ejca.2015.07.017. Epub 2015 Aug 18.


Predicting the Pathogenic Potential of BRCA1 and BRCA2 Gene Variants Identified in Clinical Genetic Testing.

Brookes C, Lai S, Doherty E, Love DR.

Sultan Qaboos Univ Med J. 2015 May;15(2):e218-25. Epub 2015 May 28.


Postdischarge Nausea and Vomiting Remains Frequent After Le Fort I Osteotomy Despite Implementation of a Multimodal Antiemetic Protocol Effective in Reducing Postoperative Nausea and Vomiting.

Brookes CD, Turvey TA, Phillips C, Kopp V, Anderson JA.

J Oral Maxillofac Surg. 2015 Jul;73(7):1259-66. doi: 10.1016/j.joms.2015.01.015. Epub 2015 Jan 29.


Seroprevalence of Antibody-Mediated, Complement-Dependent Opsonophagocytic Activity against Neisseria meningitidis Serogroup B in England.

Humphries HE, Brookes C, Allen L, Kuisma E, Gorringe A, Taylor S.

Clin Vaccine Immunol. 2015 May;22(5):503-9. doi: 10.1128/CVI.00100-15. Epub 2015 Mar 4.


Diagnostic Screening Workflow for Mutations in the BRCA1 and BRCA2 Genes.

Lai S, Brookes C, Prosser DO, Lan CC, Doherty E, Love DR.

Sultan Qaboos Univ Med J. 2015 Feb;15(1):e58-70. Epub 2015 Jan 21.


Unilateral mydriasis after maxillary osteotomy: a case series and review of the literature.

Brookes CD, Golden BA, Lawrence SD, Turvey TA.

J Oral Maxillofac Surg. 2015 Jun;73(6):1159-68. doi: 10.1016/j.joms.2014.12.024. Epub 2015 Jan 7. Review.


Postoperative nausea and vomiting following orthognathic surgery.

Phillips C, Brookes CD, Rich J, Arbon J, Turvey TA.

Int J Oral Maxillofac Surg. 2015 Jun;44(6):745-51. doi: 10.1016/j.ijom.2015.01.006. Epub 2015 Feb 2.


Antibody-mediated complement C3b/iC3b binding to group B Streptococcus in paired mother and baby serum samples in a refugee population on the Thailand-Myanmar border.

Herbert J, Thomas S, Brookes C, Turner C, Turner P, Nosten F, Le Doare K, Hudson M, Heath PT, Gorringe A, Taylor S.

Clin Vaccine Immunol. 2015 Mar;22(3):319-26. doi: 10.1128/CVI.00803-14. Epub 2015 Jan 14.


Multimodal protocol reduces postoperative nausea and vomiting in patients undergoing Le Fort I osteotomy.

Brookes CD, Berry J, Rich J, Golden BA, Turvey TA, Blakey G 3rd, Kopp V, Phillips C, Anderson J.

J Oral Maxillofac Surg. 2015 Feb;73(2):324-32. doi: 10.1016/j.joms.2014.08.007. Epub 2014 Aug 11.


Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer.

Stephen J, Murray G, Cameron DA, Thomas J, Kunkler IH, Jack W, Kerr GR, Piper T, Brookes CL, Rea DW, van de Velde CJ, Hasenburg A, Markopoulos C, Dirix L, Seynaeve C, Bartlett JM.

Br J Cancer. 2014 Dec 9;111(12):2242-7. doi: 10.1038/bjc.2014.530. Epub 2014 Oct 14.


Mutational analysis of PI3K/AKT signaling pathway in tamoxifen exemestane adjuvant multinational pathology study.

Sabine VS, Crozier C, Brookes CL, Drake C, Piper T, van de Velde CJ, Hasenburg A, Kieback DG, Markopoulos C, Dirix L, Seynaeve C, Rea DW, Bartlett JM.

J Clin Oncol. 2014 Sep 20;32(27):2951-8.


Learning from communities in the USA and England to promote equity and address the social determinants of health.

Blanchard C, Gibbs M, Narle G, Brookes C.

Glob Health Promot. 2013 Dec;20(4 Suppl):104-12. doi: 10.1177/1757975913501006.


Improving policy and practice to promote equity and social justice - a qualitative comparative analysis building on key learnings from a twinning exchange between England and the US.

Blanchard C, Narle G, Gibbs M, Ruddock C, Grady M, Brookes C, Hopkins T, Norwood J.

Glob Health Promot. 2013 Dec;20(4 Suppl):45-56. doi: 10.1177/1757975913509658.


Identification of vaccine antigens using integrated proteomic analyses of surface immunogens from serogroup B Neisseria meningitidis.

Tsolakos N, Brookes C, Taylor S, Gorringe A, Tang CM, Feavers IM, Wheeler JX.

J Proteomics. 2014 Apr 14;101:63-76. doi: 10.1016/j.jprot.2014.02.013. Epub 2014 Feb 21.


EBV-associated post-transplant lymphoproliferative disorder following in vivo T-cell-depleted allogeneic transplantation: clinical features, viral load correlates and prognostic factors in the rituximab era.

Fox CP, Burns D, Parker AN, Peggs KS, Harvey CM, Natarajan S, Marks DI, Jackson B, Chakupurakal G, Dennis M, Lim Z, Cook G, Carpenter B, Pettitt AR, Mathew S, Connelly-Smith L, Yin JA, Viskaduraki M, Chakraverty R, Orchard K, Shaw BE, Byrne JL, Brookes C, Craddock CF, Chaganti S.

Bone Marrow Transplant. 2014 Feb;49(2):280-6. doi: 10.1038/bmt.2013.170. Epub 2013 Nov 11.


Salford's journey to improvement.

Tsai J, Brookes C, Inglesby-Burke E, Moran S.

Health Serv J. 2013 Sep 13;123(6366):34-5. No abstract available.


Do type 1 receptor tyrosine kinases inform treatment choice? A prospectively planned analysis of the TEAM trial.

Bartlett JM, Brookes CL, Piper T, van de Velde CJ, Stocken D, Lyttle N, Hasenburg A, Quintayo MA, Kieback DG, Putter H, Markopoulos C, Kranenbarg EM, Mallon EA, Dirix LY, Seynaeve C, Rea DW.

Br J Cancer. 2013 Oct 29;109(9):2453-61. doi: 10.1038/bjc.2013.609. Epub 2013 Oct 3.


Diagnostic genetics at a distance: von hippel-lindau disease and a novel mutation.

Brookes C, Prosser DO, Love JM, Gardner RJ, Love DR.

Genet Res Int. 2013;2013:189196. doi: 10.1155/2013/189196. Epub 2013 Aug 26.


Evolution of active catalysts for the selective oxidative dehydrogenation of methanol on Fe2O3 surface doped with Mo oxide.

Bowker M, Brookes C, Carley AF, House MP, Kosif M, Sankar G, Wawata I, Wells PP, Yaseneva P.

Phys Chem Chem Phys. 2013 Aug 7;15(29):12056-67. doi: 10.1039/c3cp50399b. Epub 2013 Apr 3.


Development of a large scale human complement source for use in bacterial immunoassays.

Brookes C, Kuisma E, Alexander F, Allen L, Tipton T, Ram S, Gorringe A, Taylor S.

J Immunol Methods. 2013 May 31;391(1-2):39-49. doi: 10.1016/j.jim.2013.02.007. Epub 2013 Feb 26.


Post-transplant T cell chimerism predicts graft versus host disease but not disease relapse in patients undergoing an alemtuzumab based reduced intensity conditioned allogeneic transplant.

Nikolousis E, Robinson S, Nagra S, Brookes C, Kinsella F, Tauro S, Jeffries S, Griffiths M, Mahendra P, Cook M, Paneesha S, Lovell R, Kishore B, Chaganti S, Malladi R, Raghavan M, Moss P, Milligan D, Craddock C.

Leuk Res. 2013 May;37(5):561-5. doi: 10.1016/j.leukres.2013.01.010. Epub 2013 Feb 5.


Patterns of relapse in glioblastoma multiforme following concomitant chemoradiotherapy with temozolomide.

Sherriff J, Tamangani J, Senthil L, Cruickshank G, Spooner D, Jones B, Brookes C, Sanghera P.

Br J Radiol. 2013 Feb;86(1022):20120414. doi: 10.1259/bjr.20120414.


Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia.

Craddock C, Quek L, Goardon N, Freeman S, Siddique S, Raghavan M, Aztberger A, Schuh A, Grimwade D, Ivey A, Virgo P, Hills R, McSkeane T, Arrazi J, Knapper S, Brookes C, Davies B, Price A, Wall K, Griffiths M, Cavenagh J, Majeti R, Weissman I, Burnett A, Vyas P.

Leukemia. 2013 Apr;27(5):1028-36. doi: 10.1038/leu.2012.312. Epub 2012 Nov 6.


Structural characterisation, stability and antibody recognition of chimeric NHBA-GNA1030: an investigational vaccine component against Neisseria meningitidis.

Martino A, Magagnoli C, De Conciliis G, D'Ascenzi S, Forster MJ, Allen L, Brookes C, Taylor S, Bai X, Findlow J, Feavers IM, Rodger A, Bolgiano B.

Vaccine. 2012 Feb 8;30(7):1330-42. doi: 10.1016/j.vaccine.2011.12.066. Epub 2011 Dec 27.


Treatment of left ventricular non-compaction with cardiac resynchronization therapy.

Guha K, Treibel TA, Roussin I, Prasad SK, Duncan AM, Brookes C, McDonagh TA, Sharma R.

QJM. 2013 Jun;106(6):575-9. doi: 10.1093/qjmed/hcr201. Epub 2011 Oct 22. No abstract available.


Induction of immune responses by purified outer membrane protein complexes from Neisseria meningitidis.

Marzoa J, Sánchez S, Costoya L, Diéguez-Casal E, Freixeiro P, Brookes C, Allen L, Taylor S, Gorringe AR, Ferreirós CM, Criado MT.

Vaccine. 2012 Mar 16;30(13):2387-95. doi: 10.1016/j.vaccine.2011.08.123. Epub 2011 Sep 10.


Ontogeny stage-independent and high-level clonal expansion in vitro of mouse hematopoietic stem cells stimulated by an engineered NUP98-HOX fusion transcription factor.

Sekulovic S, Gasparetto M, Lecault V, Hoesli CA, Kent DG, Rosten P, Wan A, Brookes C, Hansen CL, Piret JM, Smith C, Eaves CJ, Humphries RK.

Blood. 2011 Oct 20;118(16):4366-76. doi: 10.1182/blood-2011-04-350066. Epub 2011 Aug 24.


Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells.

Sekulovic S, Gylfadottir V, Vulto I, Gasparetto M, Even Y, Brookes C, Smith C, Eaves CJ, Lansdorp PM, Rossi FM, Humphries RK.

Blood. 2011 Aug 18;118(7):1766-73. doi: 10.1182/blood-2010-11-319632. Epub 2011 Jul 5.


Classification of cell signalling in tissue development.

Platt CC, Nicholls C, Brookes C, Wood I.

Cell Commun Adhes. 2011 Feb;18(1-2):9-17. doi: 10.3109/15419061.2011.586755. Epub 2011 Jun 8. Review.


Estrogen receptor and progesterone receptor as predictive biomarkers of response to endocrine therapy: a prospectively powered pathology study in the Tamoxifen and Exemestane Adjuvant Multinational trial.

Bartlett JM, Brookes CL, Robson T, van de Velde CJ, Billingham LJ, Campbell FM, Grant M, Hasenburg A, Hille ET, Kay C, Kieback DG, Putter H, Markopoulos C, Kranenbarg EM, Mallon EA, Dirix L, Seynaeve C, Rea D.

J Clin Oncol. 2011 Apr 20;29(12):1531-8. doi: 10.1200/JCO.2010.30.3677. Epub 2011 Mar 21.


Characterising stutter in forensic STR multiplexes.

Brookes C, Bright JA, Harbison S, Buckleton J.

Forensic Sci Int Genet. 2012 Jan;6(1):58-63. doi: 10.1016/j.fsigen.2011.02.001. Epub 2011 Mar 8.


Where the eyes have it.

Feeney A, Brookes C, Gibbons H.

Nurs Stand. 2010 Jan 6-12;24(18):62-3. No abstract available.


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