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Do Risk-Enhancing Factors Enhance Risk Estimation?

Stern RH, Brook RD.

Circ Cardiovasc Qual Outcomes. 2019 Nov;12(11):e006078. doi: 10.1161/CIRCOUTCOMES.119.006078. Epub 2019 Nov 13. No abstract available.


Effects of Race on Statin Prescribing for Primary Prevention With High Atherosclerotic Cardiovascular Disease Risk in a Large Healthcare System.

Dorsch MP, Lester CA, Ding Y, Joseph M, Brook RD.

J Am Heart Assoc. 2019 Nov 19;8(22):e014709. doi: 10.1161/JAHA.119.014709. Epub 2019 Nov 11.


Acute differences in pulse wave velocity, augmentation index, and central pulse pressure following controlled exposures to cookstove air pollution in the Subclinical Tests of Volunteers Exposed to Smoke (SToVES) study.

Walker ES, Fedak KM, Good N, Balmes J, Brook RD, Clark ML, Cole-Hunter T, Dinenno F, Devlin RB, L'Orange C, Luckasen G, Mehaffy J, Shelton R, Wilson A, Volckens J, Peel JL.

Environ Res. 2019 Oct 17;180:108831. doi: 10.1016/j.envres.2019.108831. [Epub ahead of print]


Cardiopulmonary Exercise Testing Following Open Repair for a Proximal Thoracic Aortic Aneurysm or Dissection.

Hornsby WE, Norton EL, Fink S, Saberi S, Wu X, McGowan CL, Brook RD, Jones LW, Willer CJ, Patel HJ, Eagle KA, Lavie CJ, Rubenfire M, Yang B.

J Cardiopulm Rehabil Prev. 2019 Aug 29. doi: 10.1097/HCR.0000000000000446. [Epub ahead of print]


Acute Blood Pressure and Cardiovascular Effects of Near-Roadway Exposures With and Without N95 Respirators.

Morishita M, Wang L, Speth K, Zhou N, Bard RL, Li F, Brook JR, Rajagopalan S, Brook RD.

Am J Hypertens. 2019 Oct 16;32(11):1054-1065. doi: 10.1093/ajh/hpz113.


Study protocol for a stepped-wedge randomized cookstove intervention in rural Honduras: household air pollution and cardiometabolic health.

Young BN, Peel JL, Benka-Coker ML, Rajkumar S, Walker ES, Brook RD, Nelson TL, Volckens J, L'Orange C, Good N, Quinn C, Keller JP, Weller ZD, Africano S, Osorto Pinel AB, Clark ML.

BMC Public Health. 2019 Jul 8;19(1):903. doi: 10.1186/s12889-019-7214-2.


Acute Effects on Blood Pressure Following Controlled Exposure to Cookstove Air Pollution in the STOVES Study.

Fedak KM, Good N, Walker ES, Balmes J, Brook RD, Clark ML, Cole-Hunter T, Devlin R, L'Orange C, Luckasen G, Mehaffy J, Shelton R, Wilson A, Volckens J, Peel JL.

J Am Heart Assoc. 2019 Jul 16;8(14):e012246. doi: 10.1161/JAHA.119.012246. Epub 2019 Jul 9.



Byrd JB, Brook RD.

Ann Intern Med. 2019 May 7;170(9):ITC65-ITC80. doi: 10.7326/AITC201905070.


Interventions to Reduce Personal Exposures to Air Pollution: A Primer for Health Care Providers.

Bard RL, Ijaz MK, Zhang JJ, Li Y, Bai C, Yang Y, Garcia WD, Creek J, Brook RD.

Glob Heart. 2019 Mar;14(1):47-60. doi: 10.1016/j.gheart.2019.02.001. No abstract available.


Fishin' Mission on Emissions.

Rajagopalan S, Brook RD.

J Am Coll Cardiol. 2019 Apr 30;73(16):2086-2088. doi: 10.1016/j.jacc.2018.12.094. No abstract available.


Regional differences in rate of FEV1 decline in COPD: lessons from SUMMIT.

Celli BR, Anderson JA, Brook RD, Calverley PMA, Cowans NJ, Crim C, Martinez F, Newby DE, Yates J, Vestbo J.

Eur Respir J. 2019 Jun 27;53(6). pii: 1900278. doi: 10.1183/13993003.00278-2019. Print 2019 Jun. No abstract available.


Hypertriglyceridaemia-induced pancreatitis prompted by acute corticosteroid treatment: caution for clinicians.

Kim DS, O'Hayer PJ, Rubenfire M, Brook RD.

Intern Med J. 2019 Mar;49(3):411-412. doi: 10.1111/imj.14228. No abstract available.


Impact of pre-enrolment medication use on clinical outcomes in SUMMIT.

Vestbo J, Dransfield M, Anderson JA, Brook RD, Calverley PMA, Celli BR, Cowans NJ, Crim C, Martinez F, Newby DE, Yates J, Lange P.

ERJ Open Res. 2019 Feb 25;5(1). pii: 00203-2018. doi: 10.1183/23120541.00203-2018. eCollection 2019 Feb.


Volcanic smog and cardiometabolic health: Hawaiian hypertension?

Brook RD, Brook JR, Tam EK.

J Clin Hypertens (Greenwich). 2019 Apr;21(4):533-535. doi: 10.1111/jch.13500. Epub 2019 Feb 22. No abstract available.


Exposure to household air pollution from biomass cookstoves and self-reported symptoms among women in rural Honduras.

Walker ES, Clark ML, Young BN, Rajkumar S, Benka-Coker ML, Bachand AM, Brook RD, Nelson TL, Volckens J, Reynolds SJ, L'Orange C, Africano S, Osorto Pinel AB, Good N, Koehler K, Peel JL.

Int J Environ Health Res. 2019 Feb 13:1-14. doi: 10.1080/09603123.2019.1579304. [Epub ahead of print]


Limitations in the Methodology Assessing Blood Pressure and the Need for Strict Exclusion Criteria-Reply.

Brook RD, Morishita M.

JAMA Intern Med. 2019 Feb 1;179(2):275-276. doi: 10.1001/jamainternmed.2018.7483. No abstract available.


The 2017 ACC/AHA Hypertension Guidelines: Should they have included proven nonpharmacological blood pressure-lowering strategies such as Transcendental Meditation?

Schneider RH, Fields JZ, Brook RD.

J Clin Hypertens (Greenwich). 2019 Mar;21(3):434. doi: 10.1111/jch.13488. Epub 2019 Feb 4. No abstract available.


Ambient Air Pollution Is Associated With HDL (High-Density Lipoprotein) Dysfunction in Healthy Adults.

Li J, Zhou C, Xu H, Brook RD, Liu S, Yi T, Wang Y, Feng B, Zhao M, Wang X, Zhao Q, Chen J, Song X, Wang T, Liu S, Zhang Y, Wu R, Gao J, Pan B, Pennathur S, Rajagopalan S, Huo Y, Zheng L, Huang W.

Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):513-522. doi: 10.1161/ATVBAHA.118.311749.


Ambient air pollution is associated with cardiac repolarization abnormalities in healthy adults.

Xu H, Chen J, Zhao Q, Zhang Y, Wang T, Feng B, Wang Y, Liu S, Yi T, Liu S, Wu R, Zhang Q, Fang J, Song X, Rajagopalan S, Li J, Brook RD, Huang W.

Environ Res. 2019 Apr;171:239-246. doi: 10.1016/j.envres.2019.01.023. Epub 2019 Jan 14.


Improving Blood Pressure Among African Americans With Hypertension Using a Mobile Health Approach (the MI-BP App): Protocol for a Randomized Controlled Trial.

Buis LR, Dawood K, Kadri R, Dawood R, Richardson CR, Djuric Z, Sen A, Plegue M, Hutton D, Brody A, McNaughton CD, Brook RD, Levy P.

JMIR Res Protoc. 2019 Jan 25;8(1):e12601. doi: 10.2196/12601.


Extreme Levels of Air Pollution Associated With Changes in Biomarkers of Atherosclerotic Plaque Vulnerability and Thrombogenicity in Healthy Adults.

Xu H, Wang T, Liu S, Brook RD, Feng B, Zhao Q, Song X, Yi T, Chen J, Zhang Y, Wang Y, Zheng L, Rajagopalan S, Li J, Huang W.

Circ Res. 2019 Mar;124(5):e30-e43. doi: 10.1161/CIRCRESAHA.118.313948.


Household air pollution from biomass-burning cookstoves and metabolic syndrome, blood lipid concentrations, and waist circumference in Honduran women: A cross-sectional study.

Rajkumar S, Young BN, Clark ML, Benka-Coker ML, Bachand AM, Brook RD, Nelson TL, Volckens J, Reynolds SJ, L'Orange C, Good N, Koehler K, Africano S, Osorto Pinel AB, Peel JL.

Environ Res. 2019 Mar;170:46-55. doi: 10.1016/j.envres.2018.12.010. Epub 2018 Dec 10.


Reduction of personal PM2.5 exposure via indoor air filtration systems in Detroit: an intervention study.

Maestas MM, Brook RD, Ziemba RA, Li F, Crane RC, Klaver ZM, Bard RL, Spino CA, Adar SD, Morishita M.

J Expo Sci Environ Epidemiol. 2019 Jun;29(4):484-490. doi: 10.1038/s41370-018-0085-2. Epub 2018 Nov 12.


Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association.

Carey RM, Calhoun DA, Bakris GL, Brook RD, Daugherty SL, Dennison-Himmelfarb CR, Egan BM, Flack JM, Gidding SS, Judd E, Lackland DT, Laffer CL, Newton-Cheh C, Smith SM, Taler SJ, Textor SC, Turan TN, White WB; American Heart Association Professional/Public Education and Publications Committee of the Council on Hypertension; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Genomic and Precision Medicine; Council on Peripheral Vascular Disease; Council on Quality of Care and Outcomes Research; and Stroke Council.

Hypertension. 2018 Nov;72(5):e53-e90. doi: 10.1161/HYP.0000000000000084.


Air Pollution and Cardiovascular Disease: JACC State-of-the-Art Review.

Rajagopalan S, Al-Kindi SG, Brook RD.

J Am Coll Cardiol. 2018 Oct 23;72(17):2054-2070. doi: 10.1016/j.jacc.2018.07.099. Review.


Reported obstructive sleep apnea does not diminish the cardiometabolic health benefits from a comprehensive lifestyle intervention program.

Farrehi PM, Brook RD, Godley R, Walden P, Jiang Q, Rubenfire M.

J Clin Hypertens (Greenwich). 2018 Nov;20(11):1610-1614. doi: 10.1111/jch.13406. Epub 2018 Oct 12.


Computational model-based assessment of baroreflex function from response to Valsalva maneuver.

Kosinski SA, Carlson BE, Hummel SL, Brook RD, Beard DA.

J Appl Physiol (1985). 2018 Dec 1;125(6):1944-1967. doi: 10.1152/japplphysiol.00095.2018. Epub 2018 Sep 20.


Effect of Portable Air Filtration Systems on Personal Exposure to Fine Particulate Matter and Blood Pressure Among Residents in a Low-Income Senior Facility: A Randomized Clinical Trial.

Morishita M, Adar SD, D'Souza J, Ziemba RA, Bard RL, Spino C, Brook RD.

JAMA Intern Med. 2018 Oct 1;178(10):1350-1357. doi: 10.1001/jamainternmed.2018.3308.


Exposure to household air pollution from biomass cookstoves and blood pressure among women in rural Honduras: A cross-sectional study.

Young BN, Clark ML, Rajkumar S, Benka-Coker ML, Bachand A, Brook RD, Nelson TL, Volckens J, Reynolds SJ, L'Orange C, Good N, Koehler K, Africano S, Osorto Pinel AB, Peel JL.

Indoor Air. 2019 Jan;29(1):130-142. doi: 10.1111/ina.12507. Epub 2018 Oct 15.


Cardiac Troponin I and Cardiovascular Risk in Patients With Chronic Obstructive Pulmonary Disease.

Adamson PD, Anderson JA, Brook RD, Calverley PMA, Celli BR, Cowans NJ, Crim C, Dixon IJ, Martinez FJ, Newby DE, Vestbo J, Yates JC, Mills NL.

J Am Coll Cardiol. 2018 Sep 4;72(10):1126-1137. doi: 10.1016/j.jacc.2018.06.051. Erratum in: J Am Coll Cardiol. 2018 Oct 30;72(18):2282.


Blood pressure, heart rate, and mortality in chronic obstructive pulmonary disease: the SUMMIT trial.

Byrd JB, Newby DE, Anderson JA, Calverley PMA, Celli BR, Cowans NJ, Crim C, Martinez FJ, Vestbo J, Yates J, Brook RD; SUMMIT Investigators.

Eur Heart J. 2018 Sep 1;39(33):3128-3134. doi: 10.1093/eurheartj/ehy451.


Effect of Ambient Fine Particulate Matter Air Pollution and Colder Outdoor Temperatures on High-Density Lipoprotein Function.

Mathew AV, Yu J, Guo Y, Byun J, Chen YE, Wang L, Liu M, Bard RL, Morishita M, Huang W, Li J, Harkema JR, Rajagopalan S, Pennathur S, Brook RD.

Am J Cardiol. 2018 Aug 15;122(4):565-570. doi: 10.1016/j.amjcard.2018.04.061. Epub 2018 Jul 11.


Echoes from Gaea, Poseidon, Hephaestus, and Prometheus: environmental risk factors for high blood pressure.

Sharma P, Brook RD.

J Hum Hypertens. 2018 Sep;32(8-9):594-607. doi: 10.1038/s41371-018-0078-6. Epub 2018 Jun 13. Review.


Exposure to household air pollution from biomass-burning cookstoves and HbA1c and diabetic status among Honduran women.

Rajkumar S, Clark ML, Young BN, Benka-Coker ML, Bachand AM, Brook RD, Nelson TL, Volckens J, Reynolds SJ, L'Orange C, Good N, Koehler K, Africano S, Osorto Pinel AB, Peel JL.

Indoor Air. 2018 Jun 13. doi: 10.1111/ina.12484. [Epub ahead of print]


A novel homozygous ABCA1 variant in an asymptomatic man with profound hypoalphalipoproteinemia.

Carcora Y, Brook RD, Farhat L, Willer CJ, Rubenfire M, Kim DS.

J Clin Lipidol. 2018 Jul - Aug;12(4):878-882. doi: 10.1016/j.jacl.2018.04.005. Epub 2018 Apr 21.


Exacerbations of Chronic Obstructive Pulmonary Disease and Cardiac Events. A Post Hoc Cohort Analysis from the SUMMIT Randomized Clinical Trial.

Kunisaki KM, Dransfield MT, Anderson JA, Brook RD, Calverley PMA, Celli BR, Crim C, Hartley BF, Martinez FJ, Newby DE, Pragman AA, Vestbo J, Yates JC, Niewoehner DE; SUMMIT Investigators.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):51-57. doi: 10.1164/rccm.201711-2239OC.


Short-Term Blood Pressure Responses to Ambient Fine Particulate Matter Exposures at the Extremes of Global Air Pollution Concentrations.

Huang W, Wang L, Li J, Liu M, Xu H, Liu S, Chen J, Zhang Y, Morishita M, Bard RL, Harkema JR, Rajagopalan S, Brook RD.

Am J Hypertens. 2018 Apr 13;31(5):590-599. doi: 10.1093/ajh/hpx216.


β-Blocker Therapy and Clinical Outcomes in Patients with Moderate Chronic Obstructive Pulmonary Disease and Heightened Cardiovascular Risk. An Observational Substudy of SUMMIT.

Dransfield MT, McAllister DA, Anderson JA, Brook RD, Calverley PMA, Celli BR, Crim C, Gallot N, Martinez FJ, Scanlon PD, Yates J, Vestbo J, Newby DE; SUMMIT Investigators.

Ann Am Thorac Soc. 2018 May;15(5):608-614. doi: 10.1513/AnnalsATS.201708-626OC.


Cigarette smoking and response to inhaled corticosteroids in COPD.

Bhatt SP, Anderson JA, Brook RD, Calverley PMA, Celli BR, Cowans NJ, Crim C, Martinez FJ, Newby DE, Vestbo J, Yates JC, Dransfield MT.

Eur Respir J. 2018 Jan 18;51(1). pii: 1701393. doi: 10.1183/13993003.01393-2017. Print 2018 Jan. No abstract available.


Prior Medications and the Cardiovascular Benefits From Combination Angiotensin-Converting Enzyme Inhibition Plus Calcium Channel Blockade Among High-Risk Hypertensive Patients.

Brook RD, Kaciroti N, Bakris G, Dahlöf B, Pitt B, Velazquez E, Weber M, Zappe DH, Hau T, Jamerson KA.

J Am Heart Assoc. 2018 Jan 4;7(1). pii: e006940. doi: 10.1161/JAHA.117.006940.


Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways.

Rao X, Zhong J, Brook RD, Rajagopalan S.

Antioxid Redox Signal. 2018 Mar 20;28(9):797-818. doi: 10.1089/ars.2017.7394. Epub 2017 Dec 12. Review.


Acute Response to a 2-Minute Isometric Exercise Test Predicts the Blood Pressure-Lowering Efficacy of Isometric Resistance Training in Young Adults.

Somani YB, Baross AW, Brook RD, Milne KJ, McGowan CL, Swaine IL.

Am J Hypertens. 2018 Feb 9;31(3):362-368. doi: 10.1093/ajh/hpx173.


Extreme levels of ambient air pollution adversely impact cardiac and central aortic hemodynamics: the AIRCMD-China study.

Liu S, Brook RD, Huang W, Fan Z, Xu H, Wu R, Sun Z, Zhao X, Ruan Y, Yan J, Sun L, Liang R, Lian H, Gu D, Rajagopalan S.

J Am Soc Hypertens. 2017 Nov;11(11):754-761.e3. doi: 10.1016/j.jash.2017.09.009. Epub 2017 Sep 28.


Personal-level exposure to environmental temperature is a superior predictor of endothelial-dependent vasodilatation than outdoor-ambient level.

Ejike C, Wang L, Liu M, Wang W, Morishita M, Bard RL, Huang W, Harkema J, Rajagopalan S, Brook RD.

J Am Soc Hypertens. 2017 Nov;11(11):746-753.e1. doi: 10.1016/j.jash.2017.09.006. Epub 2017 Sep 28.


Pneumonia risk with inhaled fluticasone furoate and vilanterol in COPD patients with moderate airflow limitation: The SUMMIT trial.

Crim C, Calverley PMA, Anderson JA, Holmes AP, Kilbride S, Martinez FJ, Brook RD, Newby DE, Yates JC, Celli BR, Vestbo J; SUMMIT investigators.

Respir Med. 2017 Oct;131:27-34. doi: 10.1016/j.rmed.2017.07.060. Epub 2017 Aug 1.


Association of Genetic Variants Related to CETP Inhibitors and Statins With Lipoprotein Levels and Cardiovascular Risk.

Ference BA, Kastelein JJP, Ginsberg HN, Chapman MJ, Nicholls SJ, Ray KK, Packard CJ, Laufs U, Brook RD, Oliver-Williams C, Butterworth AS, Danesh J, Smith GD, Catapano AL, Sabatine MS.

JAMA. 2017 Sep 12;318(10):947-956. doi: 10.1001/jama.2017.11467.


"Stressed" About Air Pollution: Time for Personal Action.

Brook RD, Rajagopalan S.

Circulation. 2017 Aug 15;136(7):628-631. doi: 10.1161/CIRCULATIONAHA.117.029688. No abstract available.


Fluticasone Furoate, Vilanterol, and Lung Function Decline in Patients with Moderate Chronic Obstructive Pulmonary Disease and Heightened Cardiovascular Risk.

Calverley PMA, Anderson JA, Brook RD, Crim C, Gallot N, Kilbride S, Martinez FJ, Yates J, Newby DE, Vestbo J, Wise R, Celli BR; SUMMIT (Study to Understand Mortality and Morbidity) Investigators.

Am J Respir Crit Care Med. 2018 Jan 1;197(1):47-55. doi: 10.1164/rccm.201610-2086OC.


Air Pollution and Cardiometabolic Disease: An Update and Call for Clinical Trials.

Brook RD, Newby DE, Rajagopalan S.

Am J Hypertens. 2017 Dec 8;31(1):1-10. doi: 10.1093/ajh/hpx109. Review.

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