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Items: 37


Adult Neurogenesis in the Subventricular Zone and Its Regulation After Ischemic Stroke: Implications for Therapeutic Approaches.

Dillen Y, Kemps H, Gervois P, Wolfs E, Bronckaers A.

Transl Stroke Res. 2019 Jul 15. doi: 10.1007/s12975-019-00717-8. [Epub ahead of print] Review.


Non-pulsed Sinusoidal Electromagnetic Field Rescues Animals From Severe Ischemic Stroke via NO Activation.

Font LP, Cardonne MM, Kemps H, Meesen R, Salmon OF, González FG, Lambrichts I, Rigo JM, Brône B, Bronckaers A.

Front Neurosci. 2019 Jun 19;13:561. doi: 10.3389/fnins.2019.00561. eCollection 2019.


Preconditioning of Human Dental Pulp Stem Cells with Leukocyte- and Platelet-Rich Fibrin-Derived Factors Does Not Enhance Their Neuroregenerative Effect.

Gervois P, Ratajczak J, Wolfs E, Vangansewinkel T, Dillen Y, Merckx G, Bronckaers A, Lambrichts I.

Stem Cells Int. 2019 Apr 8;2019:8589149. doi: 10.1155/2019/8589149. eCollection 2019.


Angiogenic Properties of 'Leukocyte- and Platelet-Rich Fibrin'.

Ratajczak J, Vangansewinkel T, Gervois P, Merckx G, Hilkens P, Quirynen M, Lambrichts I, Bronckaers A.

Sci Rep. 2018 Oct 2;8(1):14632. doi: 10.1038/s41598-018-32936-8.


Stem Cells for Cartilage Repair: Preclinical Studies and Insights in Translational Animal Models and Outcome Measures.

Lo Monaco M, Merckx G, Ratajczak J, Gervois P, Hilkens P, Clegg P, Bronckaers A, Vandeweerd JM, Lambrichts I.

Stem Cells Int. 2018 Feb 5;2018:9079538. doi: 10.1155/2018/9079538. eCollection 2018. Review.


The Angiogenic Potential of DPSCs and SCAPs in an In Vivo Model of Dental Pulp Regeneration.

Hilkens P, Bronckaers A, Ratajczak J, Gervois P, Wolfs E, Lambrichts I.

Stem Cells Int. 2017;2017:2582080. doi: 10.1155/2017/2582080. Epub 2017 Sep 5.


Dental Pulp Stem Cells: Their Potential in Reinnervation and Angiogenesis by Using Scaffolds.

Lambrichts I, Driesen RB, Dillen Y, Gervois P, Ratajczak J, Vangansewinkel T, Wolfs E, Bronckaers A, Hilkens P.

J Endod. 2017 Sep;43(9S):S12-S16. doi: 10.1016/j.joen.2017.06.001. Epub 2017 Aug 3.


Paracrine Maturation and Migration of SH-SY5Y Cells by Dental Pulp Stem Cells.

Gervois P, Wolfs E, Dillen Y, Hilkens P, Ratajczak J, Driesen RB, Vangansewinkel T, Bronckaers A, Brône B, Struys T, Lambrichts I.

J Dent Res. 2017 Jun;96(6):654-662. doi: 10.1177/0022034517690491. Epub 2017 Jan 31.


Angiogenic Capacity of Periodontal Ligament Stem Cells Pretreated with Deferoxamine and/or Fibroblast Growth Factor-2.

Ratajczak J, Hilkens P, Gervois P, Wolfs E, Jacobs R, Lambrichts I, Bronckaers A.

PLoS One. 2016 Dec 9;11(12):e0167807. doi: 10.1371/journal.pone.0167807. eCollection 2016.


Cryopreservation and Banking of Dental Stem Cells.

Hilkens P, Driesen RB, Wolfs E, Gervois P, Vangansewinkel T, Ratajczak J, Dillen Y, Bronckaers A, Lambrichts I.

Adv Exp Med Biol. 2016;951:199-235. Review.


The β2-Adrenoceptor Agonist Terbutaline Stimulates Angiogenesis via Akt and ERK Signaling.

Lemmens S, Kusters L, Bronckaers A, Geurts N, Hendrix S.

J Cell Physiol. 2017 Feb;232(2):298-308. doi: 10.1002/jcp.25483. Epub 2016 Jul 20.


Stem Cell-Based Therapies for Ischemic Stroke: Preclinical Results and the Potential of Imaging-Assisted Evaluation of Donor Cell Fate and Mechanisms of Brain Regeneration.

Gervois P, Wolfs E, Ratajczak J, Dillen Y, Vangansewinkel T, Hilkens P, Bronckaers A, Lambrichts I, Struys T.

Med Res Rev. 2016 Nov;36(6):1080-1126. doi: 10.1002/med.21400. Epub 2016 Jul 21. Review.


The Neurovascular Properties of Dental Stem Cells and Their Importance in Dental Tissue Engineering.

Ratajczak J, Bronckaers A, Dillen Y, Gervois P, Vangansewinkel T, Driesen RB, Wolfs E, Lambrichts I, Hilkens P.

Stem Cells Int. 2016;2016:9762871. doi: 10.1155/2016/9762871. Epub 2016 Sep 5. Review.


Cardiac atrial appendage stem cells promote angiogenesis in vitro and in vivo.

Fanton Y, Houbrechts C, Willems L, Daniëls A, Linsen L, Ratajczak J, Bronckaers A, Lambrichts I, Declercq J, Rummens JL, Hendrikx M, Hensen K.

J Mol Cell Cardiol. 2016 Aug;97:235-44. doi: 10.1016/j.yjmcc.2016.06.005. Epub 2016 Jun 9.


In vivo evidence for long-term vascular remodeling resulting from chronic cerebral hypoperfusion in mice.

Struys T, Govaerts K, Oosterlinck W, Casteels C, Bronckaers A, Koole M, Van Laere K, Herijgers P, Lambrichts I, Himmelreich U, Dresselaers T.

J Cereb Blood Flow Metab. 2017 Feb;37(2):726-739. doi: 10.1177/0271678X16638349. Epub 2016 Jul 20.


Cross-linking versus RAGE: How do high molecular weight advanced glycation products induce cardiac dysfunction?

Deluyker D, Ferferieva V, Noben JP, Swennen Q, Bronckaers A, Lambrichts I, Rigo JM, Bito V.

Int J Cardiol. 2016 May 1;210:100-8. doi: 10.1016/j.ijcard.2016.02.095. Epub 2016 Feb 18.


Neuroinflammatory signals enhance the immunomodulatory and neuroprotective properties of multipotent adult progenitor cells.

Ravanidis S, Bogie JF, Donders R, Craeye D, Mays RW, Deans R, Gijbels K, Bronckaers A, Stinissen P, Pinxteren J, Hellings N.

Stem Cell Res Ther. 2015 Sep 16;6:176. doi: 10.1186/s13287-015-0169-z.


Dental Stem Cells in Pulp Regeneration: Near Future or Long Road Ahead?

Hilkens P, Meschi N, Lambrechts P, Bronckaers A, Lambrichts I.

Stem Cells Dev. 2015 Jul 15;24(14):1610-22. doi: 10.1089/scd.2014.0510. Epub 2015 May 20. Review.


Neurogenic maturation of human dental pulp stem cells following neurosphere generation induces morphological and electrophysiological characteristics of functional neurons.

Gervois P, Struys T, Hilkens P, Bronckaers A, Ratajczak J, Politis C, Brône B, Lambrichts I, Martens W.

Stem Cells Dev. 2015 Feb 1;24(3):296-311. doi: 10.1089/scd.2014.0117. Epub 2014 Oct 20.


Pro-angiogenic impact of dental stem cells in vitro and in vivo.

Hilkens P, Fanton Y, Martens W, Gervois P, Struys T, Politis C, Lambrichts I, Bronckaers A.

Stem Cell Res. 2014 May;12(3):778-90. doi: 10.1016/j.scr.2014.03.008. Epub 2014 Apr 1.


Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis.

Bronckaers A, Hilkens P, Martens W, Gervois P, Ratajczak J, Struys T, Lambrichts I.

Pharmacol Ther. 2014 Aug;143(2):181-96. doi: 10.1016/j.pharmthera.2014.02.013. Epub 2014 Mar 1. Review.


Human dental pulp stem cells can differentiate into Schwann cells and promote and guide neurite outgrowth in an aligned tissue-engineered collagen construct in vitro.

Martens W, Sanen K, Georgiou M, Struys T, Bronckaers A, Ameloot M, Phillips J, Lambrichts I.

FASEB J. 2014 Apr;28(4):1634-43. doi: 10.1096/fj.13-243980. Epub 2013 Dec 18.


Angiogenic properties of human dental pulp stem cells.

Bronckaers A, Hilkens P, Fanton Y, Struys T, Gervois P, Politis C, Martens W, Lambrichts I.

PLoS One. 2013 Aug 7;8(8):e71104. doi: 10.1371/journal.pone.0071104. eCollection 2013.


Dental stem cells and their promising role in neural regeneration: an update.

Martens W, Bronckaers A, Politis C, Jacobs R, Lambrichts I.

Clin Oral Investig. 2013 Dec;17(9):1969-83. doi: 10.1007/s00784-013-1030-3. Epub 2013 Jul 12. Review.


Effect of isolation methodology on stem cell properties and multilineage differentiation potential of human dental pulp stem cells.

Hilkens P, Gervois P, Fanton Y, Vanormelingen J, Martens W, Struys T, Politis C, Lambrichts I, Bronckaers A.

Cell Tissue Res. 2013 Jul;353(1):65-78. doi: 10.1007/s00441-013-1630-x. Epub 2013 May 29.


Magnetic resonance imaging of human dental pulp stem cells in vitro and in vivo.

Struys T, Ketkar-Atre A, Gervois P, Leten C, Hilkens P, Martens W, Bronckaers A, Dresselaers T, Politis C, Lambrichts I, Himmelreich U.

Cell Transplant. 2013;22(10):1813-29. doi: 10.3727/096368912X657774. Epub 2012 Oct 8.


Expression pattern of basal markers in human dental pulp stem cells and tissue.

Martens W, Wolfs E, Struys T, Politis C, Bronckaers A, Lambrichts I.

Cells Tissues Organs. 2012;196(6):490-500. doi: 10.1159/000338654. Epub 2012 Jun 27.


The thymidine phosphorylase inhibitor 5'-O-tritylinosine (KIN59) is an antiangiogenic multitarget fibroblast growth factor-2 antagonist.

Liekens S, Bronckaers A, Belleri M, Bugatti A, Sienaert R, Ribatti D, Nico B, Gigante A, Casanova E, Opdenakker G, Pérez-Pérez MJ, Balzarini J, Presta M.

Mol Cancer Ther. 2012 Apr;11(4):817-29. doi: 10.1158/1535-7163.MCT-11-0738. Epub 2012 Feb 1.


The COOH-terminal peptide of platelet factor-4 variant (CXCL4L1/PF-4var47-70) strongly inhibits angiogenesis and suppresses B16 melanoma growth in vivo.

Vandercappellen J, Liekens S, Bronckaers A, Noppen S, Ronsse I, Dillen C, Belleri M, Mitola S, Proost P, Presta M, Struyf S, Van Damme J.

Mol Cancer Res. 2010 Mar;8(3):322-34. doi: 10.1158/1541-7786.MCR-09-0176. Epub 2010 Mar 9.


Improvement of purine and pyrimidine antimetabolite-based anticancer treatment by selective suppression of mycoplasma-encoded catabolic enzymes.

Liekens S, Bronckaers A, Balzarini J.

Lancet Oncol. 2009 Jun;10(6):628-35. doi: 10.1016/S1470-2045(09)70037-3.


The dual role of thymidine phosphorylase in cancer development and chemotherapy.

Bronckaers A, Gago F, Balzarini J, Liekens S.

Med Res Rev. 2009 Nov;29(6):903-53. doi: 10.1002/med.20159. Review.


Identification of aspartic acid-203 in human thymidine phosphorylase as an important residue for both catalysis and non-competitive inhibition by the small molecule "crystallization chaperone" 5'-O-tritylinosine (KIN59).

Bronckaers A, Aguado L, Negri A, Camarasa MJ, Balzarini J, Pérez-Pérez MJ, Gago F, Liekens S.

Biochem Pharmacol. 2009 Aug 1;78(3):231-40. doi: 10.1016/j.bcp.2009.04.011. Epub 2009 Apr 21.


The cytostatic activity of pyrimidine nucleosides is strongly modulated by Mycoplasma hyorhinis infection: Implications for cancer therapy.

Bronckaers A, Balzarini J, Liekens S.

Biochem Pharmacol. 2008 Jul 15;76(2):188-97. doi: 10.1016/j.bcp.2008.04.019. Epub 2008 May 4.


Targeting platelet-derived endothelial cell growth factor/thymidine phosphorylase for cancer therapy.

Liekens S, Bronckaers A, Pérez-Pérez MJ, Balzarini J.

Biochem Pharmacol. 2007 Dec 3;74(11):1555-67. Epub 2007 May 16. Review.


Structural basis for non-competitive product inhibition in human thymidine phosphorylase: implications for drug design.

El Omari K, Bronckaers A, Liekens S, Pérez-Pérez MJ, Balzarini J, Stammers DK.

Biochem J. 2006 Oct 15;399(2):199-204.


5'-O-tritylated nucleoside derivatives: inhibition of thymidine phosphorylase and angiogenesis.

Liekens S, Bronckaers A, Hernández AI, Priego EM, Casanova E, Camarasa MJ, Pérez-Pérez MJ, Balzarini J.

Mol Pharmacol. 2006 Aug;70(2):501-9. Epub 2006 May 4.


Eicosanoids mediate the laminarin-induced nodulation response in larvae of the flesh fly, Neobellieria bullata.

Franssens V, Simonet G, Bronckaers A, Claeys I, De Loof A, Vanden Broeck J.

Arch Insect Biochem Physiol. 2005 May;59(1):32-41.


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