Sort by
Items per page

Send to

Choose Destination

Search results

Items: 16


Inducible Cell Fusion Permits Use of Competitive Fitness Profiling in the Human Pathogenic Fungus Aspergillus fumigatus.

Macdonald D, Thomson DD, Johns A, Contreras Valenzuela A, Gilsenan JM, Lord KM, Bowyer P, Denning DW, Read ND, Bromley MJ.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01615-18. doi: 10.1128/AAC.01615-18. Print 2019 Jan.


Development of an adaptable headspace sampling method for metabolic profiling of the fungal volatome.

Ahmed WM, Geranios P, White IR, Lawal O, Nijsen TM, Bromley MJ, Goodacre R, Read ND, Fowler SJ.

Analyst. 2018 Aug 20;143(17):4155-4162. doi: 10.1039/c8an00841h.


Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus.

Gsaller F, Furukawa T, Carr PD, Rash B, Jöchl C, Bertuzzi M, Bignell EM, Bromley MJ.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e02593-17. doi: 10.1128/AAC.02593-17. Print 2018 Jun.


The cytochrome b5 CybE is regulated by iron availability and is crucial for azole resistance in A. fumigatus.

Misslinger M, Gsaller F, Hortschansky P, Müller C, Bracher F, Bromley MJ, Haas H.

Metallomics. 2017 Nov 15;9(11):1655-1665. doi: 10.1039/c7mt00110j.


A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity.

Johns A, Scharf DH, Gsaller F, Schmidt H, Heinekamp T, Straßburger M, Oliver JD, Birch M, Beckmann N, Dobb KS, Gilsenan J, Rash B, Bignell E, Brakhage AA, Bromley MJ.

MBio. 2017 Jul 18;8(4). pii: e01504-16. doi: 10.1128/mBio.01504-16.


Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression.

Beattie SR, Mark KMK, Thammahong A, Ries LNA, Dhingra S, Caffrey-Carr AK, Cheng C, Black CC, Bowyer P, Bromley MJ, Obar JJ, Goldman GH, Cramer RA.

PLoS Pathog. 2017 Apr 19;13(4):e1006340. doi: 10.1371/journal.ppat.1006340. eCollection 2017 Apr.


Comprehensive Proteomic Profiling of Wheat Gluten Using a Combination of Data-Independent and Data-Dependent Acquisition.

Bromilow SN, Gethings LA, Langridge JI, Shewry PR, Buckley M, Bromley MJ, Mills EN.

Front Plant Sci. 2017 Jan 10;7:2020. doi: 10.3389/fpls.2016.02020. eCollection 2016.


Correction: Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.

Gsaller F, Hortschansky P, Furukawa T, Carr PD, Rash B, Capilla J, Müller C, Bracher F, Bowyer P, Haas H, Brakhage AA, Bromley MJ.

PLoS Pathog. 2016 Dec 14;12(12):e1006106. doi: 10.1371/journal.ppat.1006106. eCollection 2016 Dec.


F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase.

Oliver JD, Sibley GEM, Beckmann N, Dobb KS, Slater MJ, McEntee L, du Pré S, Livermore J, Bromley MJ, Wiederhold NP, Hope WW, Kennedy AJ, Law D, Birch M.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12809-12814. doi: 10.1073/pnas.1608304113. Epub 2016 Oct 25.


Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.

Gsaller F, Hortschansky P, Furukawa T, Carr PD, Rash B, Capilla J, Müller C, Bracher F, Bowyer P, Haas H, Brakhage AA, Bromley MJ.

PLoS Pathog. 2016 Jul 20;12(7):e1005775. doi: 10.1371/journal.ppat.1005775. eCollection 2016 Jul. Erratum in: PLoS Pathog. 2016 Dec 14;12 (12 ):e1006106.


Infectious Disease. How to bolster the antifungal pipeline.

Denning DW, Bromley MJ.

Science. 2015 Mar 27;347(6229):1414-6. doi: 10.1126/science.aaa6097. Epub 2015 Mar 26. No abstract available.


Occurrence of azole-resistant species of Aspergillus in the UK environment.

Bromley MJ, van Muijlwijk G, Fraczek MG, Robson G, Verweij PE, Denning DW, Bowyer P.

J Glob Antimicrob Resist. 2014 Dec;2(4):276-279. doi: 10.1016/j.jgar.2014.05.004. Epub 2014 Jun 21.


Elevated levels of the neutrophil chemoattractant pro-platelet basic protein in macrophages from individuals with chronic and allergic aspergillosis.

Smith NL, Bromley MJ, Denning DW, Simpson A, Bowyer P.

J Infect Dis. 2015 Feb 15;211(4):651-60. doi: 10.1093/infdis/jiu490. Epub 2014 Sep 5.


The Aspergillus fumigatus dihydroxyacid dehydratase Ilv3A/IlvC is required for full virulence.

Oliver JD, Kaye SJ, Tuckwell D, Johns AE, Macdonald DA, Livermore J, Warn PA, Birch M, Bromley MJ.

PLoS One. 2012;7(9):e43559. doi: 10.1371/journal.pone.0043559. Epub 2012 Sep 18.


The transposon impala is activated by low temperatures: use of a controlled transposition system to identify genes critical for viability of Aspergillus fumigatus.

Carr PD, Tuckwell D, Hey PM, Simon L, d'Enfert C, Birch M, Oliver JD, Bromley MJ.

Eukaryot Cell. 2010 Mar;9(3):438-48. doi: 10.1128/EC.00324-09. Epub 2010 Jan 22.


Gene essentiality in Aspergillus fumigatus.

Turner G, Allen GJ, Keszenman-Pereyra D, Bromley MJ.

Med Mycol. 2006 Sep 1;44(Supplement_1):S87-S90. doi: 10.1080/13693780600898011.


Supplemental Content

Loading ...
Support Center