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Items: 15

1.

Serotonin receptors of 5-HT2 type in the hypothalamic arcuate nuclei (ARC) positively regulate liver cytochrome P450 via stimulation of the growth hormone-releasing hormone - growth hormone (GHRH-GH) hormonal pathway.

Bromek E, Rysz M, Haduch A, Daniel WA.

Drug Metab Dispos. 2018 Dec 5. pii: dmd.118.083808. doi: 10.1124/dmd.118.083808. [Epub ahead of print]

PMID:
30518657
2.

Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver.

Bromek E, Rysz M, Haduch A, Wójcikowski J, Daniel WA.

Drug Metab Dispos. 2018 Jun;46(6):786-793. doi: 10.1124/dmd.117.079632. Epub 2018 Mar 19.

PMID:
29555828
3.

The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11.

Rysz M, Bromek E, Haduch A, Liskova B, Wójcikowski J, Daniel WA.

Biochem Pharmacol. 2016 Jul 15;112:82-9. doi: 10.1016/j.bcp.2016.04.017. Epub 2016 Apr 29.

PMID:
27137992
4.

Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain.

Haduch A, Bromek E, Wójcikowski J, Gołembiowska K, Daniel WA.

Drug Metab Dispos. 2016 Mar;44(3):445-52. doi: 10.1124/dmd.115.067413.

5.

Activation of brain serotonergic system by repeated intracerebral administration of 5-hydroxytryptophan (5-HTP) decreases the expression and activity of liver cytochrome P450.

Rysz M, Bromek E, Daniel WA.

Biochem Pharmacol. 2016 Jan 1;99:113-22. doi: 10.1016/j.bcp.2015.11.014. Epub 2015 Nov 12.

PMID:
26581122
6.

Damage to the Brain Serotonergic System Increases the Expression of Liver Cytochrome P450.

Rysz M, Bromek E, Haduch A, Sadakierska-Chudy A, Daniel WA.

Drug Metab Dispos. 2015 Sep;43(9):1345-52. doi: 10.1124/dmd.115.064980. Epub 2015 Jun 9.

7.

The role of the dorsal noradrenergic pathway of the brain (locus coeruleus) in the regulation of liver cytochrome P450 activity.

Kot M, Sadakierska-Chudy A, Haduch A, Rysz M, Bromek E, Gołembiowska K, Daniel WA.

Eur J Pharmacol. 2015 Mar 15;751:34-41. doi: 10.1016/j.ejphar.2015.01.014. Epub 2015 Jan 28.

PMID:
25637782
8.

The cytochrome P450 2D-mediated formation of serotonin from 5-methoxytryptamine in the brain in vivo: a microdialysis study.

Haduch A, Bromek E, Kot M, Kamińska K, Gołembiowska K, Daniel WA.

J Neurochem. 2015 Apr;133(1):83-92. doi: 10.1111/jnc.13031. Epub 2015 Feb 8.

9.

Role of brain cytochrome P450 (CYP2D) in the metabolism of monoaminergic neurotransmitters.

Anna Haduch A, Bromek E, Daniel WA.

Pharmacol Rep. 2013;65(6):1519-28. Review.

10.

Involvement of the paraventricular (PVN) and arcuate (ARC) nuclei of the hypothalamus in the central noradrenergic regulation of liver cytochrome P450.

Bromek E, Wójcikowski J, Daniel WA.

Biochem Pharmacol. 2013 Dec 1;86(11):1614-20. doi: 10.1016/j.bcp.2013.09.006. Epub 2013 Sep 17.

PMID:
24051135
11.

The catalytic competence of cytochrome P450 in the synthesis of serotonin from 5-methoxytryptamine in the brain: an in vitro study.

Haduch A, Bromek E, Sadakierska-Chudy A, Wójcikowski J, Daniel WA.

Pharmacol Res. 2013 Jan;67(1):53-9. doi: 10.1016/j.phrs.2012.10.009. Epub 2012 Oct 23.

PMID:
23098818
12.

Cytochrome P450 mediates dopamine formation in the brain in vivo.

Bromek E, Haduch A, Gołembiowska K, Daniel WA.

J Neurochem. 2011 Sep;118(5):806-15. doi: 10.1111/j.1471-4159.2011.07339.x. Epub 2011 Jul 14.

13.

The effect of psychotropic drugs on cytochrome P450 2D (CYP2D) in rat brain.

Haduch A, Bromek E, Daniel WA.

Eur J Pharmacol. 2011 Jan 25;651(1-3):51-8. doi: 10.1016/j.ejphar.2010.10.077. Epub 2010 Nov 27.

PMID:
21115002
14.

The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study.

Bromek E, Haduch A, Daniel WA.

Eur J Pharmacol. 2010 Jan 25;626(2-3):171-8. doi: 10.1016/j.ejphar.2009.09.062. Epub 2009 Oct 8.

PMID:
19818757
15.

Effect of mirtazapine on the CYP2D activity in the primary culture of rat hepatocytes.

Haduch A, Bromek E, Kot M, Jemnitz K, Veres Z, Vereczkey L, Daniel WA.

Pharmacol Rep. 2006 Nov-Dec;58(6):979-84.

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