Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 146

1.

Testing Pleiotropy vs. Separate QTL in Multiparental Populations.

Boehm FJ, Chesler EJ, Yandell BS, Broman KW.

G3 (Bethesda). 2019 Jul 9;9(7):2317-2324. doi: 10.1534/g3.119.400098.

2.

Cleaning Genotype Data from Diversity Outbred Mice.

Broman KW, Gatti DM, Svenson KL, Sen Ś, Churchill GA.

G3 (Bethesda). 2019 May 7;9(5):1571-1579. doi: 10.1534/g3.119.400165.

3.

R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations.

Broman KW, Gatti DM, Simecek P, Furlotte NA, Prins P, Sen Ś, Yandell BS, Churchill GA.

Genetics. 2019 Feb;211(2):495-502. doi: 10.1534/genetics.118.301595. Epub 2018 Dec 27.

4.

A novel locus on mouse chromosome 7 that influences survival after infection with tick-borne encephalitis virus.

Palus M, Sohrabi Y, Broman KW, Strnad H, Šíma M, Růžek D, Volkova V, Slapničková M, Vojtíšková J, Mrázková L, Salát J, Lipoldová M.

BMC Neurosci. 2018 Jul 6;19(1):39. doi: 10.1186/s12868-018-0438-8.

5.

Genetic Drivers of Pancreatic Islet Function.

Keller MP, Gatti DM, Schueler KL, Rabaglia ME, Stapleton DS, Simecek P, Vincent M, Allen S, Broman AT, Bacher R, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD.

Genetics. 2018 May;209(1):335-356. doi: 10.1534/genetics.118.300864. Epub 2018 Mar 22.

6.

Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats.

Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal A, Francic S, Cui L, Gatti DM, Broman KW, Tschannen M, Tsaih SW, Zagloul M, Kim Y, Baur B, Fox J, Robinson M, Levy S, Flister MJ, Mott R, Valdar W, Solberg Woods LC.

Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28.

7.

A modified vaccinia Ankara vaccine vector expressing a mosaic H5 hemagglutinin reduces viral shedding in rhesus macaques.

Florek NW, Kamlangdee A, Mutschler JP, Kingstad-Bakke B, Schultz-Darken N, Broman KW, Osorio JE, Friedrich TC.

PLoS One. 2017 Aug 3;12(8):e0181738. doi: 10.1371/journal.pone.0181738. eCollection 2017.

8.

The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.

Keller MP, Paul PK, Rabaglia ME, Stapleton DS, Schueler KL, Broman AT, Ye SI, Leng N, Brandon CJ, Neto EC, Plaisier CL, Simonett SP, Kebede MA, Sheynkman GM, Klein MA, Baliga NS, Smith LM, Broman KW, Yandell BS, Kendziorski C, Attie AD.

PLoS Genet. 2016 Dec 9;12(12):e1006466. doi: 10.1371/journal.pgen.1006466. eCollection 2016 Dec.

9.

Recombination rate variation in mice from an isolated island.

Wang RJ, Gray MM, Parmenter MD, Broman KW, Payseur BA.

Mol Ecol. 2017 Jan;26(2):457-470. doi: 10.1111/mec.13932. Epub 2016 Dec 21.

10.

Genetics of Skeletal Evolution in Unusually Large Mice from Gough Island.

Parmenter MD, Gray MM, Hogan CA, Ford IN, Broman KW, Vinyard CJ, Payseur BA.

Genetics. 2016 Dec;204(4):1559-1572. Epub 2016 Sep 30.

11.

A Spontaneous Missense Mutation in Branched Chain Keto Acid Dehydrogenase Kinase in the Rat Affects Both the Central and Peripheral Nervous Systems.

Zigler JS Jr, Hodgkinson CA, Wright M, Klise A, Sundin O, Broman KW, Hejtmancik F, Huang H, Patek B, Sergeev Y, Hose S, Brayton C, Xaiodong J, Vasquez D, Maragakis N, Mori S, Goldman D, Hoke A, Sinha D.

PLoS One. 2016 Jul 29;11(7):e0160447. doi: 10.1371/journal.pone.0160447. eCollection 2016.

12.

Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice.

De Simone M, Spagnuolo L, Lorè NI, Cigana C, De Fino I, Broman KW, Iraqi FA, Bragonzi A.

BMC Genomics. 2016 May 11;17:351. doi: 10.1186/s12864-016-2676-4.

13.

The Dissection of Expression Quantitative Trait Locus Hotspots.

Tian J, Keller MP, Broman AT, Kendziorski C, Yandell BS, Attie AD, Broman KW.

Genetics. 2016 Apr;202(4):1563-74. doi: 10.1534/genetics.115.183624. Epub 2016 Feb 2.

14.

Correlations between Synaptic Initiation and Meiotic Recombination: A Study of Humans and Mice.

Gruhn JR, Al-Asmar N, Fasnacht R, Maylor-Hagen H, Peinado V, Rubio C, Broman KW, Hunt PA, Hassold T.

Am J Hum Genet. 2016 Jan 7;98(1):102-15. doi: 10.1016/j.ajhg.2015.11.019. Epub 2015 Dec 31.

15.

Mapping Quantitative Trait Loci Underlying Function-Valued Traits Using Functional Principal Component Analysis and Multi-Trait Mapping.

Kwak IY, Moore CR, Spalding EP, Broman KW.

G3 (Bethesda). 2015 Nov 3;6(1):79-86. doi: 10.1534/g3.115.024133.

16.

Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets.

Tian J, Keller MP, Oler AT, Rabaglia ME, Schueler KL, Stapleton DS, Broman AT, Zhao W, Kendziorski C, Yandell BS, Hagenbuch B, Broman KW, Attie AD.

Genetics. 2015 Nov;201(3):1253-62. doi: 10.1534/genetics.115.179432. Epub 2015 Sep 18.

17.

Identification and Correction of Sample Mix-Ups in Expression Genetic Data: A Case Study.

Broman KW, Keller MP, Broman AT, Kendziorski C, Yandell BS, Sen Ś, Attie AD.

G3 (Bethesda). 2015 Aug 19;5(10):2177-86. doi: 10.1534/g3.115.019778.

18.

Genetics of Rapid and Extreme Size Evolution in Island Mice.

Gray MM, Parmenter MD, Hogan CA, Ford I, Cuthbert RJ, Ryan PG, Broman KW, Payseur BA.

Genetics. 2015 Sep;201(1):213-28. doi: 10.1534/genetics.115.177790. Epub 2015 Jul 20.

19.

R/qtlcharts: interactive graphics for quantitative trait locus mapping.

Broman KW.

Genetics. 2015 Feb;199(2):359-61. doi: 10.1534/genetics.114.172742. Epub 2014 Dec 18.

20.

Quantitative trait locus mapping identifies candidate alleles involved in adaptive introgression and range expansion in a wild sunflower.

Whitney KD, Broman KW, Kane NC, Hovick SM, Randell RA, Rieseberg LH.

Mol Ecol. 2015 May;24(9):2194-211. doi: 10.1111/mec.13044. Epub 2015 Jan 21.

21.

Fourteen Years of R/qtl: Just Barely Sustainable.

Broman KW.

J Open Res Softw. 2014 Jul 9;2(1). pii: e11.

22.

Quantitative trait locus mapping methods for diversity outbred mice.

Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA.

G3 (Bethesda). 2014 Sep 18;4(9):1623-33. doi: 10.1534/g3.114.013748.

23.

Modified vaccinia virus Ankara encoding influenza virus hemagglutinin induces heterosubtypic immunity in macaques.

Florek NW, Weinfurter JT, Jegaskanda S, Brewoo JN, Powell TD, Young GR, Das SC, Hatta M, Broman KW, Hungnes O, Dudman SG, Kawaoka Y, Kent SJ, Stinchcomb DT, Osorio JE, Friedrich TC.

J Virol. 2014 Nov;88(22):13418-28. doi: 10.1128/JVI.01219-14. Epub 2014 Sep 10.

24.

Examining variation in recombination levels in the human female: a test of the production-line hypothesis.

Rowsey R, Gruhn J, Broman KW, Hunt PA, Hassold T.

Am J Hum Genet. 2014 Jul 3;95(1):108-12. doi: 10.1016/j.ajhg.2014.06.008.

25.

Resistance to noise-induced hearing loss in 129S6 and MOLF mice: identification of independent, overlapping, and interacting chromosomal regions.

Street VA, Kujawa SG, Manichaikul A, Broman KW, Kallman JC, Shilling DJ, Iwata AJ, Robinson LC, Robbins CA, Li J, Liberman MC, Tempel BL.

J Assoc Res Otolaryngol. 2014 Oct;15(5):721-38. doi: 10.1007/s10162-014-0472-x. Epub 2014 Jun 21.

26.

A simple regression-based method to map quantitative trait loci underlying function-valued phenotypes.

Kwak IY, Moore CR, Spalding EP, Broman KW.

Genetics. 2014 Aug;197(4):1409-16. doi: 10.1534/genetics.114.166306. Epub 2014 Jun 14.

27.

Efficient imputation of missing markers in low-coverage genotyping-by-sequencing data from multiparental crosses.

Huang BE, Raghavan C, Mauleon R, Broman KW, Leung H.

Genetics. 2014 May;197(1):401-4. doi: 10.1534/genetics.113.158014. Epub 2014 Feb 28.

28.

Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males.

Baier B, Hunt P, Broman KW, Hassold T.

PLoS Genet. 2014 Jan 30;10(1):e1004125. doi: 10.1371/journal.pgen.1004125. eCollection 2014 Jan.

29.

Cytological studies of human meiosis: sex-specific differences in recombination originate at, or prior to, establishment of double-strand breaks.

Gruhn JR, Rubio C, Broman KW, Hunt PA, Hassold T.

PLoS One. 2013 Dec 20;8(12):e85075. doi: 10.1371/journal.pone.0085075. eCollection 2013.

31.

High-throughput computer vision introduces the time axis to a quantitative trait map of a plant growth response.

Moore CR, Johnson LS, Kwak IY, Livny M, Broman KW, Spalding EP.

Genetics. 2013 Nov;195(3):1077-86. doi: 10.1534/genetics.113.153346. Epub 2013 Aug 26.

32.

Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus.

Harris M, Burns CM, Becker EA, Braasch AT, Gostick E, Johnson RC, Broman KW, Price DA, Friedrich TC, O'Connor SL.

J Virol. 2013 Aug;87(16):9353-64. doi: 10.1128/JVI.00909-13. Epub 2013 Jun 19.

33.

FMR1 CGG expansions: prevalence and sex ratios.

Maenner MJ, Baker MW, Broman KW, Tian J, Barnes JK, Atkins A, McPherson E, Hong J, Brilliant MH, Mailick MR.

Am J Med Genet B Neuropsychiatr Genet. 2013 Jul;162B(5):466-73. doi: 10.1002/ajmg.b.32176. Epub 2013 Jun 5.

34.

The Lsktm1 locus modulates lung and skin tumorigenesis in the mouse.

Galvan A, Colombo F, Noci S, Pazzaglia S, Mancuso M, Manenti G, Broman KW, Saran A, Dragani TA.

G3 (Bethesda). 2012 Sep;2(9):1041-6. doi: 10.1534/g3.112.003525. Epub 2012 Sep 1.

35.

Ex vivo SIV-specific CD8 T cell responses in heterozygous animals are primarily directed against peptides presented by a single MHC haplotype.

Greene JM, Chin EN, Budde ML, Lhost JJ, Hines PJ, Burwitz BJ, Broman KW, Nelson JE, Friedrich TC, O'Connor DH.

PLoS One. 2012;7(8):e43690. doi: 10.1371/journal.pone.0043690. Epub 2012 Aug 22.

36.

Mapping quantitative trait loci onto a phylogenetic tree.

Broman KW, Kim S, Sen S, Ané C, Payseur BA.

Genetics. 2012 Sep;192(1):267-79. doi: 10.1534/genetics.112.142448. Epub 2012 Jun 28.

37.

Quantile-based permutation thresholds for quantitative trait loci hotspots.

Neto EC, Keller MP, Broman AF, Attie AD, Jansen RC, Broman KW, Yandell BS.

Genetics. 2012 Aug;191(4):1355-65. doi: 10.1534/genetics.112.139451. Epub 2012 Jun 1.

38.

Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis.

Wang CY, Stapleton DS, Schueler KL, Rabaglia ME, Oler AT, Keller MP, Kendziorski CM, Broman KW, Yandell BS, Schadt EE, Attie AD.

J Lipid Res. 2012 Aug;53(8):1493-501. doi: 10.1194/jlr.M025239. Epub 2012 May 23.

39.

Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource.

King EG, Merkes CM, McNeil CL, Hoofer SR, Sen S, Broman KW, Long AD, Macdonald SJ.

Genome Res. 2012 Aug;22(8):1558-66. doi: 10.1101/gr.134031.111. Epub 2012 Apr 10.

40.

Haplotype probabilities in advanced intercross populations.

Broman KW.

G3 (Bethesda). 2012 Feb;2(2):199-202. doi: 10.1534/g3.111.001818. Epub 2012 Feb 1.

41.

Genotype probabilities at intermediate generations in the construction of recombinant inbred lines.

Broman KW.

Genetics. 2012 Feb;190(2):403-12. doi: 10.1534/genetics.111.132647.

42.

xQTL workbench: a scalable web environment for multi-level QTL analysis.

Arends D, van der Velde KJ, Prins P, Broman KW, Möller S, Jansen RC, Swertz MA.

Bioinformatics. 2012 Apr 1;28(7):1042-4. doi: 10.1093/bioinformatics/bts049. Epub 2012 Feb 3.

43.

Arlm1 is a male-specific modifier of astrocytoma resistance on mouse Chr 12.

Amlin-Van Schaick JC, Kim S, DiFabio C, Lee MH, Broman KW, Reilly KM.

Neuro Oncol. 2012 Feb;14(2):160-74. doi: 10.1093/neuonc/nor206. Epub 2012 Jan 10.

44.

Scram1 is a modifier of spinal cord resistance for astrocytoma on mouse Chr 5.

Amlin-Van Schaick J, Kim S, Broman KW, Reilly KM.

Mamm Genome. 2012 Apr;23(3-4):277-85. doi: 10.1007/s00335-011-9380-0. Epub 2011 Dec 8.

45.

Cross-reactive T cells are involved in rapid clearance of 2009 pandemic H1N1 influenza virus in nonhuman primates.

Weinfurter JT, Brunner K, Capuano SV 3rd, Li C, Broman KW, Kawaoka Y, Friedrich TC.

PLoS Pathog. 2011 Nov;7(11):e1002381. doi: 10.1371/journal.ppat.1002381. Epub 2011 Nov 10.

46.

Systems genetics of susceptibility to obesity-induced diabetes in mice.

Davis RC, van Nas A, Castellani LW, Zhao Y, Zhou Z, Wen P, Yu S, Qi H, Rosales M, Schadt EE, Broman KW, Péterfy M, Lusis AJ.

Physiol Genomics. 2012 Jan 18;44(1):1-13. doi: 10.1152/physiolgenomics.00003.2011. Epub 2011 Oct 18.

47.

An SNP-Based Linkage Map for Zebrafish Reveals Sex Determination Loci.

Bradley KM, Breyer JP, Melville DB, Broman KW, Knapik EW, Smith JR.

G3 (Bethesda). 2011 Jun 1;1(1):3-9.

48.

Differential MHC class I expression in distinct leukocyte subsets.

Greene JM, Wiseman RW, Lank SM, Bimber BN, Karl JA, Burwitz BJ, Lhost JJ, Hawkins OE, Kunstman KJ, Broman KW, Wolinsky SM, Hildebrand WH, O'Connor DH.

BMC Immunol. 2011 Jul 15;12:39. doi: 10.1186/1471-2172-12-39.

49.

Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques.

Moreland AJ, Guethlein LA, Reeves RK, Broman KW, Johnson RP, Parham P, O'Connor DH, Bimber BN.

BMC Genomics. 2011 Jun 7;12:295. doi: 10.1186/1471-2164-12-295.

50.

Genetic analysis of complex traits in the emerging Collaborative Cross.

Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, de Villena FP, Churchill GA.

Genome Res. 2011 Aug;21(8):1213-22. doi: 10.1101/gr.111310.110. Epub 2011 Mar 15.

Supplemental Content

Loading ...
Support Center