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Items: 1 to 50 of 84

1.

Pharmacokinetic analysis of [68Ga]Ga-DOTA-TOC PET in meningiomas for assessment of in vivo somatostatin receptor subtype 2.

Bashir A, Vestergaard MB, Binderup T, Broholm H, Marner L, Ziebell M, Fugleholm K, Mathiesen T, Kjær A, Law I.

Eur J Nucl Med Mol Imaging. 2020 Mar 13. doi: 10.1007/s00259-020-04759-1. [Epub ahead of print]

PMID:
32170347
2.

Angiotensinogen promoter methylation predicts bevacizumab treatment response of patients with recurrent glioblastoma.

Urup T, Gillberg L, Kaastrup K, Lü MJS, Michaelsen SR, Andrée Larsen V, Christensen IJ, Broholm H, Lassen U, Grønbaek K, Poulsen HS.

Mol Oncol. 2020 Mar 5. doi: 10.1002/1878-0261.12660. [Epub ahead of print]

3.

In vivo imaging of cell proliferation in meningioma using 3'-deoxy-3'-[18F]fluorothymidine PET/MRI.

Bashir A, Binderup T, Vestergaard MB, Broholm H, Marner L, Ziebell M, Fugleholm K, Kjær A, Law I.

Eur J Nucl Med Mol Imaging. 2020 Feb 11. doi: 10.1007/s00259-020-04704-2. [Epub ahead of print]

PMID:
32047966
4.

Poor prognosis associated with TERT gene alterations in meningioma is independent of the WHO classification: an individual patient data meta-analysis.

Mirian C, Duun-Henriksen AK, Juratli T, Sahm F, Spiegl-Kreinecker S, Peyre M, Biczok A, Tonn JC, Goutagny S, Bertero L, Maier AD, Møller Pedersen M, Law I, Broholm H, Cahill DP, Brastianos P, Poulsgaard L, Fugleholm K, Ziebell M, Munch T, Mathiesen T.

J Neurol Neurosurg Psychiatry. 2020 Apr;91(4):378-387. doi: 10.1136/jnnp-2019-322257. Epub 2020 Feb 10. Review.

PMID:
32041819
5.

Clinical Characteristics of Gliosarcoma and Outcomes From Standardized Treatment Relative to Conventional Glioblastoma.

Frandsen S, Broholm H, Larsen VA, Grunnet K, Møller S, Poulsen HS, Michaelsen SR.

Front Oncol. 2019 Dec 17;9:1425. doi: 10.3389/fonc.2019.01425. eCollection 2019.

6.

ABCB1 single-nucleotide variants and survival in patients with glioblastoma treated with radiotherapy concomitant with temozolomide.

Malmström A, Łysiak M, Åkesson L, Jakobsen I, Mudaisi M, Milos P, Hallbeck M, Fomichov V, Broholm H, Grunnet K, Poulsen HS, Bratthäll C, Strandeus M, Papagiannopoulou A, Stenmark-Askmalm M, Green H, Söderkvist P.

Pharmacogenomics J. 2020 Apr;20(2):213-219. doi: 10.1038/s41397-019-0107-z. Epub 2019 Oct 17.

PMID:
31624332
7.

Recurrent glioblastoma versus late posttreatment changes: diagnostic accuracy of O-(2-[18F]fluoroethyl)-L-tyrosine positron emission tomography (18F-FET PET).

Bashir A, Mathilde Jacobsen S, Mølby Henriksen O, Broholm H, Urup T, Grunnet K, Andrée Larsen V, Møller S, Skjøth-Rasmussen J, Skovgaard Poulsen H, Law I.

Neuro Oncol. 2019 Dec 17;21(12):1595-1606. doi: 10.1093/neuonc/noz166.

PMID:
31618420
8.

Multiple Extracranial Metastases from Primary Gliosarcoma in a Patient with Two Previous Different Primary Cancers.

Capion T, Hauerberg J, Broholm H, Muhic A.

Case Rep Oncol Med. 2019 Sep 2;2019:7849616. doi: 10.1155/2019/7849616. eCollection 2019.

9.

Molecular Characterization of the Danish Prion Diseases Cohort With Special Emphasis on Rare and Unique Cases.

Areškevičiūtė A, Broholm H, Melchior LC, Bartoletti-Stella A, Parchi P, Capellari S, Scheie D, Lund EL.

J Neuropathol Exp Neurol. 2019 Nov 1;78(11):980-992. doi: 10.1093/jnen/nlz089.

PMID:
31553446
10.

A Novel Eight Octapeptide Repeat Insertion in PRNP Causing Prion Disease in a Danish Family.

Areškevičiūtė A, Høgh P, Bartoletti-Stella A, Melchior LC, Nielsen PR, Parchi P, Capellari S, Broholm H, Scheie D, Lund EL.

J Neuropathol Exp Neurol. 2019 Jul 1;78(7):595-604. doi: 10.1093/jnen/nlz037.

PMID:
31107536
11.

Clinical and histopathological predictors of outcome in malignant meningioma.

Maier AD, Bartek J Jr, Eriksson F, Ugleholdt H, Juhler M, Broholm H, Mathiesen TI.

Neurosurg Rev. 2019 Mar 13. doi: 10.1007/s10143-019-01093-5. [Epub ahead of print]

PMID:
30868425
12.

Extracranial metastases in glioblastoma-Two case stories.

Schou Nørøxe D, Regner Michaelsen S, Broholm H, Møller S, Skovgaard Poulsen H, Lassen U.

Clin Case Rep. 2018 Dec 27;7(2):289-294. doi: 10.1002/ccr3.1980. eCollection 2019 Feb.

13.

Biomarkers in tumors of the central nervous system - a review.

Scheie D, Kufaishi HHA, Broholm H, Lund EL, de Stricker K, Melchior LC, Grauslund M.

APMIS. 2019 May;127(5):265-287. doi: 10.1111/apm.12916. Epub 2019 Feb 10. Review.

PMID:
30740783
14.

Early Postoperative 18F-FET PET/MRI for Pediatric Brain and Spinal Cord Tumors.

Marner L, Nysom K, Sehested A, Borgwardt L, Mathiasen R, Henriksen OM, Lundemann M, Munck Af Rosenschöld P, Thomsen C, Bøgeskov L, Skjøth-Rasmussen J, Juhler M, Kruse A, Broholm H, Scheie D, Lauritsen T, Forman JL, Wehner PS, Højgaard L, Law I.

J Nucl Med. 2019 Aug;60(8):1053-1058. doi: 10.2967/jnumed.118.220293. Epub 2019 Jan 25.

PMID:
30683767
15.

Advancing brain tumor epidemiology - multi-level integration and international collaboration: The 2018 Brain Tumor Epidemiology Consortium meeting report.

Johnson KJ, Broholm H, Scheurer ME, Lau CC, Hainfellner JA, Wiemels J, Schwartzbaum J.

Clin Neuropathol. 2018 Nov/Dec;37(6):254-261. doi: 10.5414/NP301148.

16.

VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance.

Michaelsen SR, Staberg M, Pedersen H, Jensen KE, Majewski W, Broholm H, Nedergaard MK, Meulengracht C, Urup T, Villingshøj M, Lukacova S, Skjøth-Rasmussen J, Brennum J, Kjær A, Lassen U, Stockhausen MT, Poulsen HS, Hamerlik P.

Neuro Oncol. 2018 Oct 9;20(11):1462-1474. doi: 10.1093/neuonc/noy103.

17.

Sporadic Creutzfeldt-Jakob Disease in a Woman Married Into a Gerstmann-Sträussler-Scheinker Family: An Investigation of Prions Transmission via Microchimerism.

Areškeviciute A, Melchior LC, Broholm H, Krarup LH, Lindquist SG, Johansen P, McKenzie N, Green A, Nielsen JE, Laursen H, Lund EL.

J Neuropathol Exp Neurol. 2018 Aug 1;77(8):673-684. doi: 10.1093/jnen/nly043.

PMID:
29889261
18.
19.

[Epilepsy surgery].

Pinborg LH, Jespersen B, Beniczky S, Fabricius M, Rasonyi G, Uldall P, Tsiropoulos I, Leffers AM, Madsen C, Foged M, Ziebell M, Henriksen O, Jørgensen M, Vinter K, Stauning L, Broholm H, Brennum J, Sabers A, Rubboli G.

Ugeskr Laeger. 2018 Mar 26;180(13). pii: V09170653. Review. Danish.

PMID:
29587957
20.

Adoptive cancer immunotherapy using DNA-demethylated T helper cells as antigen-presenting cells.

Kirkin AF, Dzhandzhugazyan KN, Guldberg P, Fang JJ, Andersen RS, Dahl C, Mortensen J, Lundby T, Wagner A, Law I, Broholm H, Madsen L, Lundell-Ek C, Gjerstorff MF, Ditzel HJ, Jensen MR, Fischer W.

Nat Commun. 2018 Mar 6;9(1):785. doi: 10.1038/s41467-018-03217-9.

21.

DNA Methylation Levels of the ELMO Gene Promoter CpG Islands in Human Glioblastomas.

Michaelsen SR, Aslan D, Urup T, Poulsen HS, Grønbæk K, Broholm H, Kristensen LS.

Int J Mol Sci. 2018 Feb 28;19(3). pii: E679. doi: 10.3390/ijms19030679.

22.

Increased cytomegalovirus replication by 5-Azacytidine and viral-induced cytoplasmic expression of DNMT‑1 in medulloblastoma and endothelial cells.

Estekizadeh A, Landázur N, Bartek J Jr, Beltoft Brøchner C, Davoudi B, Broholm H, Karimi M, Ekström TJ, Rahbar A.

Int J Oncol. 2018 Apr;52(4):1317-1327. doi: 10.3892/ijo.2018.4286. Epub 2018 Feb 26.

PMID:
29484388
23.

Biomarkers in Recurrent Grade III Glioma Patients Treated with Bevacizumab and Irinotecan.

Toft A, Urup T, Christensen IJ, Michaelsen SR, Lukram B, Grunnet K, Kosteljanetz M, Larsen VA, Lassen U, Broholm H, Poulsen HS.

Cancer Invest. 2018 Feb 7;36(2):165-174. doi: 10.1080/07357907.2018.1430818. Epub 2018 Feb 2. Review.

PMID:
29393706
24.

Molecular profiling of short-term and long-term surviving patients identifies CD34 mRNA level as prognostic for glioblastoma survival.

Michaelsen SR, Urup T, Olsen LR, Broholm H, Lassen U, Poulsen HS.

J Neurooncol. 2018 May;137(3):533-542. doi: 10.1007/s11060-017-2739-7. Epub 2018 Jan 5.

PMID:
29305787
25.

Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients.

Urup T, Staunstrup LM, Michaelsen SR, Vitting-Seerup K, Bennedbæk M, Toft A, Olsen LR, Jønson L, Issazadeh-Navikas S, Broholm H, Hamerlik P, Poulsen HS, Lassen U.

BMC Cancer. 2017 Apr 18;17(1):278. doi: 10.1186/s12885-017-3251-3.

26.

Replication stress, DNA damage signalling, and cytomegalovirus infection in human medulloblastomas.

Bartek J Jr, Fornara O, Merchut-Maya JM, Maya-Mendoza A, Rahbar A, Stragliotto G, Broholm H, Svensson M, Sehested A, Söderberg Naucler C, Bartek J, Bartkova J.

Mol Oncol. 2017 Aug;11(8):945-964. doi: 10.1002/1878-0261.12061. Epub 2017 Jun 17.

27.

Quantifying Long-Term Retention of Excised Fat Grafts: A Longitudinal, Retrospective Cohort Study of 108 Patients Followed for Up to 8.4 Years.

Herly M, Ørholt M, Glovinski PV, Pipper CB, Broholm H, Poulsgaard L, Fugleholm K, Thomsen C, Drzewiecki KT.

Plast Reconstr Surg. 2017 May;139(5):1223-1232. doi: 10.1097/PRS.0000000000003237.

PMID:
28092338
28.

Visual outcome, endocrine function and tumor control after fractionated stereotactic radiation therapy of craniopharyngiomas in adults: findings in a prospective cohort.

Astradsson A, Munck Af Rosenschöld P, Feldt-Rasmussen U, Poulsgaard L, Wiencke AK, Ohlhues L, Engelholm SA, Broholm H, Hansen Møller E, Klose M, Roed H, Juhler M.

Acta Oncol. 2017 Mar;56(3):415-421. doi: 10.1080/0284186X.2016.1270466. Epub 2017 Jan 13.

PMID:
28084862
29.

Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients.

Urup T, Michaelsen SR, Olsen LR, Toft A, Christensen IJ, Grunnet K, Winther O, Broholm H, Kosteljanetz M, Issazadeh-Navikas S, Poulsen HS, Lassen U.

Mol Oncol. 2016 Oct;10(8):1160-8. doi: 10.1016/j.molonc.2016.05.005. Epub 2016 May 26.

30.

TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy.

Munch-Petersen HD, Asmar F, Dimopoulos K, Areškevičiūtė A, Brown P, Girkov MS, Pedersen A, Sjö LD, Heegaard S, Broholm H, Kristensen LS, Ralfkiaer E, Grønbæk K.

Acta Neuropathol Commun. 2016 Apr 22;4:40. doi: 10.1186/s40478-016-0307-6.

31.

Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma.

Kristensen LS, Michaelsen SR, Dyrbye H, Aslan D, Grunnet K, Christensen IJ, Poulsen HS, Grønbæk K, Broholm H.

J Neuropathol Exp Neurol. 2016 Mar;75(3):246-55. doi: 10.1093/jnen/nlv024. Epub 2016 Feb 16.

32.

Development and validation of a prognostic model for recurrent glioblastoma patients treated with bevacizumab and irinotecan.

Urup T, Dahlrot RH, Grunnet K, Christensen IJ, Michaelsen SR, Toft A, Larsen VA, Broholm H, Kosteljanetz M, Hansen S, Poulsen HS, Lassen U.

Acta Oncol. 2016;55(4):418-22. doi: 10.3109/0284186X.2015.1114679. Epub 2016 Feb 1.

PMID:
26828563
33.

The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium.

Amirian ES, Armstrong GN, Zhou R, Lau CC, Claus EB, Barnholtz-Sloan JS, Il'yasova D, Schildkraut J, Ali-Osman F, Sadetzki S, Johansen C, Houlston RS, Jenkins RB, Lachance D, Olson SH, Bernstein JL, Merrell RT, Wrensch MR, Davis FG, Lai R, Shete S, Amos CI, Scheurer ME, Aldape K, Alafuzoff I, Brännström T, Broholm H, Collins P, Giannini C, Rosenblum M, Tihan T, Melin BS, Bondy ML.

Am J Epidemiol. 2016 Jan 15;183(2):85-91. doi: 10.1093/aje/kwv235. Epub 2015 Dec 10.

34.

Late malignant transformation of vestibular schwannoma in the absence of irradiation: case report.

Bashir A, Poulsgaard L, Broholm H, Fugleholm K.

J Neurosurg. 2016 Aug;125(2):372-7. doi: 10.3171/2015.6.JNS1544. Epub 2015 Nov 27.

PMID:
26613171
35.

KINFix--A formalin-free non-commercial fixative optimized for histological, immunohistochemical and molecular analyses of neurosurgical tissue specimens.

Stefanits H, Bienkowski M, Galanski M, Mitulovic G, Ströbel T, Gelpi E, Ribalta T, Broholm H, Hartmann C, Kros JM, Preusser M, Hainfellner JA.

Clin Neuropathol. 2016 Jan-Feb;35(1):3-12. doi: 10.5414/NP300907.

36.

VEGF-A mRNA measurement in meningiomas using a new simplified approach: branched DNA and chemiluminescence.

Dyrbye H, Nassehi D, Sørensen LP, Juhler M, Laursen H, Broholm H.

Clin Neuropathol. 2016 Jan-Feb;35(1):13-21. doi: 10.5414/NP300583.

PMID:
26413777
37.

The use of 5-ALA to assist complete removal of residual non-enhancing part of childhood medulloblastoma: a case report.

Skjøth-Rasmussen J, Bøgeskov L, Sehested A, Klausen C, Broholm H, Nysom K.

Childs Nerv Syst. 2015 Nov;31(11):2173-7. doi: 10.1007/s00381-015-2762-y. Epub 2015 Jun 13.

PMID:
26070965
38.

18F-FET microPET and microMRI for anti-VEGF and anti-PlGF response assessment in an orthotopic murine model of human glioblastoma.

Nedergaard MK, Michaelsen SR, Urup T, Broholm H, El Ali H, Poulsen HS, Stockhausen MT, Kjaer A, Lassen U.

PLoS One. 2015 Feb 13;10(2):e0115315. doi: 10.1371/journal.pone.0115315. eCollection 2015.

39.

Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-convergence on axonal guidance.

Kaalund SS, Venø MT, Bak M, Møller RS, Laursen H, Madsen F, Broholm H, Quistorff B, Uldall P, Tommerup N, Kauppinen S, Sabers A, Fluiter K, Møller LB, Nossent AY, Silahtaroglu A, Kjems J, Aronica E, Tümer Z.

Epilepsia. 2014 Dec;55(12):2017-27. doi: 10.1111/epi.12839. Epub 2014 Nov 19.

40.

Effect of nitric oxide on spinal evoked potentials and survival rate in rats with decompression sickness.

Randsoe T, Meehan CF, Broholm H, Hyldegaard O.

J Appl Physiol (1985). 2015 Jan 1;118(1):20-8. doi: 10.1152/japplphysiol.00260.2014. Epub 2014 Nov 6.

41.

Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature.

Kristoffersen K, Nedergaard MK, Villingshøj M, Borup R, Broholm H, Kjær A, Poulsen HS, Stockhausen MT.

Cancer Biol Ther. 2014 Jul;15(7):862-77. doi: 10.4161/cbt.28876. Epub 2014 Apr 22.

42.

Clinical variables serve as prognostic factors in a model for survival from glioblastoma multiforme: an observational study of a cohort of consecutive non-selected patients from a single institution.

Michaelsen SR, Christensen IJ, Grunnet K, Stockhausen MT, Broholm H, Kosteljanetz M, Poulsen HS.

BMC Cancer. 2013 Sep 3;13:402. doi: 10.1186/1471-2407-13-402.

43.

Pathophysiology of shunt dysfunction in shunt treated hydrocephalus.

Blegvad C, Skjolding AD, Broholm H, Laursen H, Juhler M.

Acta Neurochir (Wien). 2013 Sep;155(9):1763-72. doi: 10.1007/s00701-013-1729-6. Epub 2013 May 5.

PMID:
23645322
44.

Peritumoral brain edema in angiomatous supratentorial meningiomas: an investigation of the vascular endothelial growth factor A pathway.

Nassehi D, Sørensen LP, Dyrbye H, Thomsen C, Juhler M, Laursen H, Broholm H.

APMIS. 2013 Nov;121(11):1025-36. doi: 10.1111/apm.12052. Epub 2013 Feb 11.

PMID:
23398358
45.

[Danish Neuro-Oncology Registry].

Hansen S, Green A, Nielsen J, Haugaard M, Laursen R, Schultz H, Rasmussen B, Broholm H, Andersen P, Kosteljanetz M; styregruppen for DNOR.

Ugeskr Laeger. 2012 Oct 15;174(42):2558. Danish. No abstract available.

PMID:
23079461
46.

Brain perfusion CT compared with ¹⁵O-H₂O PET in patients with primary brain tumours.

Grüner JM, Paamand R, Kosteljanetz M, Broholm H, Højgaard L, Law I.

Eur J Nucl Med Mol Imaging. 2012 Nov;39(11):1691-701. doi: 10.1007/s00259-012-2173-1. Epub 2012 Jun 27.

47.

Differences in distribution and regulation of astrocytic aquaporin-4 in human and rat hydrocephalic brain.

Skjolding AD, Holst AV, Broholm H, Laursen H, Juhler M.

Neuropathol Appl Neurobiol. 2013 Feb;39(2):179-91. doi: 10.1111/j.1365-2990.2012.01275.x.

PMID:
22497211
48.

Vascular endothelial growth factor A protein level and gene expression in intracranial meningiomas with brain edema.

Nassehi D, Dyrbye H, Andresen M, Thomsen C, Juhler M, Laursen H, Broholm H.

APMIS. 2011 Dec;119(12):831-43. doi: 10.1111/j.1600-0463.2011.02764.x. Epub 2011 Oct 17.

PMID:
22085359
49.

DNA-repair gene variants are associated with glioblastoma survival.

Wibom C, Sjöström S, Henriksson R, Brännström T, Broholm H, Rydén P, Johansen C, Collatz-Laier H, Hepworth S, McKinney PA, Bethke L, Houlston RS, Andersson U, Melin BS.

Acta Oncol. 2012 Mar;51(3):325-32. doi: 10.3109/0284186X.2011.616284. Epub 2011 Oct 21.

PMID:
22017238
50.

Analysis of DNA repair gene polymorphisms and survival in low-grade and anaplastic gliomas.

Berntsson SG, Wibom C, Sjöström S, Henriksson R, Brännström T, Broholm H, Johansson C, Fleming SJ, McKinney PA, Bethke L, Houlston R, Smits A, Andersson U, Melin BS.

J Neurooncol. 2011 Dec;105(3):531-8. doi: 10.1007/s11060-011-0614-5. Epub 2011 Jun 5.

PMID:
21643987

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