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Items: 48


Burden of disease in children with respiratory tract infections in primary care: diary-based cohort study.

Schot MJC, Dekker ARJ, van Werkhoven CH, van der Velden AW, Cals JWL, Broekhuizen BDL, Hopstaken RM, de Wit NJ, Verheij TJM.

Fam Pract. 2019 Nov 18;36(6):723-729. doi: 10.1093/fampra/cmz024.


Misclassification of Both Chronic Obstructive Pulmonary Disease and Heart Failure.

Rutten FH, Broekhuizen BDL.

JAMA Netw Open. 2018 Dec 7;1(8):e185486. doi: 10.1001/jamanetworkopen.2018.5486. No abstract available.


Point-of-care C-reactive protein to assist in primary care management of children with suspected non-serious lower respiratory tract infection: a randomised controlled trial.

Schot MJ, Van den Bruel A, Broekhuizen BD, Cals JW, Noteboom EA, Balemans W, Hopstaken RM, van Delft S, de Wit NJ, Verheij TJ.

BJGP Open. 2018 Jul 11;2(3):bjgpopen18X101600. doi: 10.3399/bjgpopen18X101600. eCollection 2018 Oct.


Effectiveness of the European Society of Cardiology/Heart Failure Association website '' and an e-health adjusted care pathway in patients with stable heart failure: results of the 'e-Vita HF' randomized controlled trial.

Wagenaar KP, Broekhuizen BDL, Jaarsma T, Kok I, Mosterd A, Willems FF, Linssen GCM, Agema WRP, Anneveldt S, Lucas CMHB, Mannaerts HFJ, Wajon EMCJ, Dickstein K, Cramer MJ, Landman MAJ, Hoes AW, Rutten FH.

Eur J Heart Fail. 2019 Feb;21(2):238-246. doi: 10.1002/ejhf.1354. Epub 2018 Nov 28.


Clinical relevance of bacterial resistance in lower respiratory tract infection in primary care: secondary analysis of a multicentre European trial.

Teepe J, Broekhuizen BD, Goossens H, Hordijk PM, Loens K, Lammens C, Ieven M, Little P, Butler CC, Coenen S, Godycki-Cwirko M, Henriques-Normark B, Verheij TJ; GRACE consortium.

Br J Gen Pract. 2018 Sep;68(674):e627-e632. doi: 10.3399/bjgp18X698333. Epub 2018 Jul 30.


Effectiveness of general practitioner online training and an information booklet for parents on antibiotic prescribing for children with respiratory tract infection in primary care: a cluster randomized controlled trial.

Dekker ARJ, Verheij TJM, Broekhuizen BDL, Butler CC, Cals JWL, Francis NA, Little P, Sanders EAM, Yardley L, Zuithoff NPA, van der Velden AW.

J Antimicrob Chemother. 2018 May 1;73(5):1416-1422. doi: 10.1093/jac/dkx542.


Interpretability of the European Heart Failure Self-care Behaviour scale.

Wagenaar KP, Broekhuizen BD, Rutten FH, Strömberg A, van Stel HF, Hoes AW, Jaarsma T.

Patient Prefer Adherence. 2017 Oct 26;11:1841-1849. doi: 10.2147/PPA.S144915. eCollection 2017.


C-reactive protein point-of-care testing in children with cough: qualitative study of GPs' perceptions.

Schot MJ, Broekhuizen BD, Cals JW, Brussee E, de Wit NJ, Verheij TJ, de Groot E.

BJGP Open. 2017 Oct 27;1(4):bjgpopen17X101193. doi: 10.3399/bjgpopen17X101193. eCollection 2018 Jan.


Antimicrobial resistance in women with urinary tract infection in primary care: No relation with type 2 diabetes mellitus.

Vinken JEM, Mol HE, Verheij TJM, van Delft S, Kolader M, Ekkelenkamp MB, Rutten GEHM, Broekhuizen BDL.

Prim Care Diabetes. 2018 Feb;12(1):80-86. doi: 10.1016/j.pcd.2017.08.003. Epub 2017 Sep 14.


'', an educational website for patients and carers from the Heart Failure Association of the European Society of Cardiology: objectives, use and future directions.

Wagenaar KP, Rutten FH, Klompstra L, Bhana Y, Sieverink F, Ruschitzka F, Seferovic PM, Lainscak M, Piepoli MF, Broekhuizen BDL, Strömberg A, Jaarsma T, Hoes AW, Dickstein K.

Eur J Heart Fail. 2017 Nov;19(11):1447-1454. doi: 10.1002/ejhf.917. Epub 2017 Sep 4. Review.


The impact of penicillin allergy labels on antibiotic and health care use in primary care: a retrospective cohort study.

Su T, Broekhuizen BDL, Verheij TJM, Rockmann H.

Clin Transl Allergy. 2017 Jun 7;7:18. doi: 10.1186/s13601-017-0154-y. eCollection 2017.


Guideline adherence for diagnostic faeces testing in primary care patients with gastroenteritis.

Schierenberg A, Broekhuizen BDL, Nipshagen MD, Kommer MBJ, Bruijning-Verhagen PCJ, van Delft S, van de Pol AC, Bonten MJM, de Wit NJ.

Fam Pract. 2017 Nov 16;34(6):692-696. doi: 10.1093/fampra/cmx042.


Disease Course of Lower Respiratory Tract Infection With a Bacterial Cause.

Teepe J, Broekhuizen BD, Loens K, Lammens C, Ieven M, Goossens H, Little P, Butler CC, Coenen S, Godycki-Cwirko M, Verheij T; GRACE Consortium.

Ann Fam Med. 2016 Nov;14(6):534-539. doi: 10.1370/afm.1974.


Predicting the presence of bacterial pathogens in the airways of primary care patients with acute cough.

Teepe J, Broekhuizen BDL, Loens K, Lammens C, Ieven M, Goossens H, Little P, Butler CC, Coenen S, Godycki-Cwirko M, Verheij TJM; GRACE Consortium.

CMAJ. 2017 Jan 16;189(2):E50-E55. doi: 10.1503/cmaj.151364. Epub 2016 Oct 24.


The added value of C-reactive protein measurement in diagnosing pneumonia in primary care: a meta-analysis of individual patient data.

Minnaard MC, de Groot JAH, Hopstaken RM, Schierenberg A, de Wit NJ, Reitsma JB, Broekhuizen BDL, van Vugt SF, Neven AK, Graffelman AW, Melbye H, Rainer TH, Steurer J, Holm A, Gonzales R, Dinant GJ, van de Pol AC, Verheij TJM.

CMAJ. 2017 Jan 16;189(2):E56-E63. doi: 10.1503/cmaj.151163. Epub 2016 Sep 19.


Representativeness of Participants in Heart Failure E-Health Trials: A Report From the E-Vita HF Study.

Wagenaar KP, Hakim N, Broekhuizen BD, Jaarsma T, Rutten FH, Hoes AW.

J Card Fail. 2017 Jan;23(1):88-89. doi: 10.1016/j.cardfail.2016.08.006. Epub 2016 Aug 23. No abstract available.


Analysis of recruitment in a pragmatic observational study on C-reactive protein point-of-care testing in primary care.

Minnaard MC, van der Zand J, van de Pol AC, de Wit NJ, Schierenberg A, Hopstaken RM, van Delft S, Verheij TJ, Broekhuizen BD.

Eur J Gen Pract. 2016 Dec;22(4):219-224. doi: 10.1080/13814788.2016.1208167. Epub 2016 Aug 2.


Overdiagnosis of heart failure in primary care: a cross-sectional study.

Valk MJ, Mosterd A, Broekhuizen BD, Zuithoff NP, Landman MA, Hoes AW, Rutten FH.

Br J Gen Pract. 2016 Aug;66(649):e587-92. doi: 10.3399/bjgp16X685705. Epub 2016 Jun 6.


C-reactive protein point-of-care testing and associated antibiotic prescribing.

Minnaard MC, van de Pol AC, Hopstaken RM, van Delft S, Broekhuizen BD, Verheij TJ, de Wit NJ.

Fam Pract. 2016 Aug;33(4):408-13. doi: 10.1093/fampra/cmw039. Epub 2016 May 26.


External Validation of Prediction Models for Pneumonia in Primary Care Patients with Lower Respiratory Tract Infection: An Individual Patient Data Meta-Analysis.

Schierenberg A, Minnaard MC, Hopstaken RM, van de Pol AC, Broekhuizen BD, de Wit NJ, Reitsma JB, van Vugt SF, Graffelman AW, Melbye H, Rainer TH, Steurer J, Holm A, Gonzales R, Dinant GJ, de Groot JA, Verheij TJ.

PLoS One. 2016 Feb 26;11(2):e0149895. doi: 10.1371/journal.pone.0149895. eCollection 2016.


Design of the PROUD study: PCR faeces testing in outpatients with diarrhoea.

Schierenberg A, Nipshagen MD, Broekhuizen BDL, van de Pol AC, Bruijning-Verhagen PCJ, Kusters JG, Schuurman R, van Delft S, Mangen MJ, de Wit NJ, Bonten MJM.

BMC Infect Dis. 2016 Jan 30;16:39. doi: 10.1186/s12879-016-1371-z.


Amoxicillin for clinically unsuspected pneumonia in primary care: subgroup analysis.

Teepe J, Little P, Elshof N, Broekhuizen BD, Moore M, Stuart B, Butler CC, Hood K, Ieven M, Coenen S, Goossens H, Verheij TJ; GRACE consortium.

Eur Respir J. 2016 Jan;47(1):327-30. doi: 10.1183/13993003.00611-2015. Epub 2015 Nov 5. No abstract available.


Rationale, design and baseline results of the Treatment Optimisation in Primary care of Heart failure in the Utrecht region (TOPHU) study: a cluster randomised controlled trial.

Valk MJ, Hoes AW, Mosterd A, Landman MA, Broekhuizen BD, Rutten FH.

BMC Fam Pract. 2015 Oct 7;16:130. doi: 10.1186/s12875-015-0347-1.


Effectiveness of an interactive platform, and the ESC/HFA website in patients with heart failure: design of the multicentre randomized e-Vita heart failure trial.

Wagenaar KP, Broekhuizen BD, Dickstein K, Jaarsma T, Hoes AW, Rutten FH.

Eur J Heart Fail. 2015 Dec;17(12):1310-6. doi: 10.1002/ejhf.413. Epub 2015 Oct 1.


Prevalence, diagnosis, and disease course of pertussis in adults with acute cough: a prospective, observational study in primary care.

Teepe J, Broekhuizen BD, Ieven M, Loens K, Huygen K, Kretzschmar M, de Melker H, Butler CC, Little P, Stuart B, Coenen S, Goossens H, Verheij TJ; GRACE consortium.

Br J Gen Pract. 2015 Oct;65(639):e662-7. doi: 10.3399/bjgp15X686917.


Diagnostic and prognostic utility of mid-expiratory flow rate in older community-dwelling persons with respiratory symptoms, but without chronic obstructive pulmonary disease.

Güder G, Brenner S, Störk S, Held M, Broekhuizen BD, Lammers JW, Hoes AW, Rutten FH.

BMC Pulm Med. 2015 Jul 31;15:83. doi: 10.1186/s12890-015-0081-4.


COPD in patients with stable heart failure in the primary care setting.

Valk MJ, Broekhuizen BD, Mosterd A, Zuithoff NP, Hoes AW, Rutten FH.

Int J Chron Obstruct Pulmon Dis. 2015 Jun 26;10:1219-24. doi: 10.2147/COPD.S77085. eCollection 2015.


Validity of a clinical model to predict influenza in patients presenting with symptoms of lower respiratory tract infection in primary care.

van Vugt SF, Broekhuizen BD, Zuithoff NP, van Essen GA, Ebell MH, Coenen S, Ieven M, Lammens C, Goossens H, Butler CC, Hood K, Little P, Verheij TJ; GRACE Consortium.

Fam Pract. 2015 Aug;32(4):408-14. doi: 10.1093/fampra/cmv039. Epub 2015 Jun 4.


[The NHG guidelines 'Adult asthma' and 'COPD'].

Geijer RM, Tuut MK, in't Veen JC, Broekhuizen BD, Chavannes NH, Smeele IJ.

Ned Tijdschr Geneeskd. 2015;159:A9076. Review. Dutch.


Diagnosis of allergy against beta-lactams in primary care: prevalence and diagnostic criteria.

Salden OA, Rockmann H, Verheij TJ, Broekhuizen BD.

Fam Pract. 2015 Jun;32(3):257-62. doi: 10.1093/fampra/cmv018. Epub 2015 Apr 7.


The added diagnostic value of five different C-reactive protein point-of-care test devices in detecting pneumonia in primary care: A nested case-control study.

Minnaard MC, van de Pol AC, de Groot JA, De Wit NJ, Hopstaken RM, van Delft S, Goossens H, Ieven M, Lammens C, Little P, Butler CC, Broekhuizen BD, Verheij TJ.

Scand J Clin Lab Invest. 2015 Jul;75(4):291-5. doi: 10.3109/00365513.2015.1006136. Epub 2015 Feb 27.


[Rules and regulations threaten non-pharmacological studies in children].

Schot MJ, Broekhuizen BD, Cals JW.

Ned Tijdschr Geneeskd. 2015;160:A9354. Dutch.


Illness perception and related behaviour in lower respiratory tract infections—a European study.

Hordijk PM, Broekhuizen BD, Butler CC, Coenen S, Godycki-Cwirko M, Goossens H, Hood K, Smith R, van Vugt SF, Little P, Verheij TJ; GRACE Project Group.

Fam Pract. 2015 Apr;32(2):152-8. doi: 10.1093/fampra/cmu075. Epub 2014 Nov 18.


Medication use in European primary care patients with lower respiratory tract infection: an observational study.

Hamoen M, Broekhuizen BD, Little P, Melbye H, Coenen S, Goossens H, Butler CC, Francis NA, Verheij TJ; GRACE clinical study group.

Br J Gen Pract. 2014 Feb;64(619):e81-91. doi: 10.3399/bjgp14X677130. Review.


Use of expert panels to define the reference standard in diagnostic research: a systematic review of published methods and reporting.

Bertens LC, Broekhuizen BD, Naaktgeboren CA, Rutten FH, Hoes AW, van Mourik Y, Moons KG, Reitsma JB.

PLoS Med. 2013 Oct;10(10):e1001531. doi: 10.1371/journal.pmed.1001531. Epub 2013 Oct 15. Review.


Development and validation of a model to predict the risk of exacerbations in chronic obstructive pulmonary disease.

Bertens LC, Reitsma JB, Moons KG, van Mourik Y, Lammers JW, Broekhuizen BD, Hoes AW, Rutten FH.

Int J Chron Obstruct Pulmon Dis. 2013;8:493-9. doi: 10.2147/COPD.S49609. Epub 2013 Oct 10.


Analytical performance, agreement and user-friendliness of five C-reactive protein point-of-care tests.

Minnaard MC, van de Pol AC, Broekhuizen BD, Verheij TJ, Hopstaken RM, van Delft S, Kooijman-Buiting AM, de Groot JA, De Wit NJ.

Scand J Clin Lab Invest. 2013 Dec;73(8):627-34. doi: 10.3109/00365513.2013.841985. Epub 2013 Oct 14.


Diagnostic properties of C-reactive protein for detecting pneumonia in children.

Koster MJ, Broekhuizen BD, Minnaard MC, Balemans WA, Hopstaken RM, de Jong PA, Verheij TJ.

Respir Med. 2013 Jul;107(7):1087-93. doi: 10.1016/j.rmed.2013.04.012. Epub 2013 May 11.


Use of serum C reactive protein and procalcitonin concentrations in addition to symptoms and signs to predict pneumonia in patients presenting to primary care with acute cough: diagnostic study.

van Vugt SF, Broekhuizen BD, Lammens C, Zuithoff NP, de Jong PA, Coenen S, Ieven M, Butler CC, Goossens H, Little P, Verheij TJ; GRACE consortium.

BMJ. 2013 Apr 30;346:f2450. doi: 10.1136/bmj.f2450.


Diagnosing pneumonia in patients with acute cough: clinical judgment compared to chest radiography.

van Vugt SF, Verheij TJ, de Jong PA, Butler CC, Hood K, Coenen S, Goossens H, Little P, Broekhuizen BD; GRACE Project Group.

Eur Respir J. 2013 Oct;42(4):1076-82. doi: 10.1183/09031936.00111012. Epub 2013 Jan 24.


Accuracy of symptoms, signs, and C-reactive protein for early chronic obstructive pulmonary disease.

Broekhuizen BD, Sachs AP, Verheij TJ, Janssen KJ, Asma G, Lammers JW, Hage R, Lammers E, Hoes AW, Moons KG.

Br J Gen Pract. 2012 Sep;62(602):e632-8. doi: 10.3399/bjgp12X654605.


COPD in primary care: from episodic to continual management.

Broekhuizen BD, Sachs AP, Verheij TJ.

Br J Gen Pract. 2012 Feb;62(595):60-1. doi: 10.3399/bjgp12X625003. No abstract available.


Spirometric thresholds for diagnosing COPD: 0.70 or LLN, pre- or post-dilator values?

Mohamed Hoesein FA, Zanen P, Sachs AP, Verheij TJ, Lammers JW, Broekhuizen BD.

COPD. 2012 Aug;9(4):338-43. doi: 10.3109/15412555.2012.667851. Epub 2012 Apr 11.


Diagnostic management of chronic obstructive pulmonary disease.

Broekhuizen BD, Sachs AP, Hoes AW, Verheij TJ, Moons KG.

Neth J Med. 2012 Jan;70(1):6-11. Review.


Does a decision aid help physicians to detect chronic obstructive pulmonary disease?

Broekhuizen BD, Sachs A, Janssen K, Geersing GJ, Moons K, Hoes A, Verheij T.

Br J Gen Pract. 2011 Oct;61(591):e674-9. doi: 10.3399/bjgp11X601398.


Diagnostic value of oral prednisolone test for chronic obstructive pulmonary disorders.

Broekhuizen BD, Sachs AP, Moons KG, Cheragwandi SA, Damsté HE, Wijnands GJ, Verheij TJ, Hoes AW.

Ann Fam Med. 2011 Mar-Apr;9(2):104-9. doi: 10.1370/afm.1223.


Undetected chronic obstructive pulmonary disease and asthma in people over 50 years with persistent cough.

Broekhuizen BD, Sachs AP, Hoes AW, Moons KG, van den Berg JW, Dalinghaus WH, Lammers E, Verheij TJ.

Br J Gen Pract. 2010 Jul;60(576):489-94. doi: 10.3399/bjgp10X514738.


The diagnostic value of history and physical examination for COPD in suspected or known cases: a systematic review.

Broekhuizen BD, Sachs AP, Oostvogels R, Hoes AW, Verheij TJ, Moons KG.

Fam Pract. 2009 Aug;26(4):260-8. doi: 10.1093/fampra/cmp026. Epub 2009 May 7.


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