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Items: 1 to 50 of 123

1.

HY-DIN' in the Cilia: Discovery of Central Pair-Related Mutations in Primary Ciliary Dyskinesia.

Dutcher SK, Brody SL.

Am J Respir Cell Mol Biol. 2019 Oct 11. doi: 10.1165/rcmb.2019-0316ED. [Epub ahead of print] No abstract available.

PMID:
31604022
2.

Quantification of image texture in X-ray phase-contrast-enhanced projection images of in vivo mouse lungs observed at varied inflation pressures.

Brooks FJ, Gunsten SP, Vasireddi SK, Brody SL, Anastasio MA.

Physiol Rep. 2019 Aug;7(16):e14208. doi: 10.14814/phy2.14208.

3.

Autophagy proteins are required for club cell structure and function in airways.

Malvin NP, Kern JT, Liu TC, Brody SL, Stappenbeck TS.

Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1;317(2):L259-L270. doi: 10.1152/ajplung.00394.2018. Epub 2019 May 22.

PMID:
31116580
4.

Regulation of cilia abundance in multiciliated cells.

Nanjundappa R, Kong D, Shim K, Stearns T, Brody SL, Loncarek J, Mahjoub MR.

Elife. 2019 Apr 26;8. pii: e44039. doi: 10.7554/eLife.44039.

5.

An obligatory role for club cells in preventing obliterative bronchiolitis in lung transplants.

Liu Z, Liao F, Scozzi D, Furuya Y, Pugh KN, Hachem R, Chen DL, Cano M, Green JM, Krupnick AS, Kreisel D, Perl AKT, Huang HJ, Brody SL, Gelman AE.

JCI Insight. 2019 Apr 16;5. pii: 124732. doi: 10.1172/jci.insight.124732.

6.

Frequenting Sequencing: How Genetics Teaches Us Cilia Biology.

Horani A, Brody SL.

Am J Respir Cell Mol Biol. 2019 Oct;61(4):403-404. doi: 10.1165/rcmb.2019-0103ED. No abstract available.

7.

Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart.

Heo GS, Kopecky B, Sultan D, Ou M, Feng G, Bajpai G, Zhang X, Luehmann H, Detering L, Su Y, Leuschner F, Combadière C, Kreisel D, Gropler RJ, Brody SL, Liu Y, Lavine KJ.

Circ Res. 2019 Mar 15;124(6):881-890. doi: 10.1161/CIRCRESAHA.118.314030.

PMID:
30661445
8.

Technical Considerations for Lung Transplantation in Kartagener's Syndrome.

Gauthier JM, Takahashi T, Bierhals AJ, Brody SL, Hachem RR, Witt CA, Byers DE, Yusen RD, Trulock EP, Aguilar PR, Nava RG, Kozower BD, Meyers BF, Patterson GA, Kreisel D, Puri V.

Ann Thorac Surg. 2019 May;107(5):e337-e339. doi: 10.1016/j.athoracsur.2018.08.095. Epub 2018 Oct 26.

PMID:
30612988
9.

A liquid-like organelle at the root of motile ciliopathy.

Huizar RL, Lee C, Boulgakov AA, Horani A, Tu F, Marcotte EM, Brody SL, Wallingford JB.

Elife. 2018 Dec 18;7. pii: e38497. doi: 10.7554/eLife.38497.

10.

Intracellular C3 Protects Human Airway Epithelial Cells from Stress-associated Cell Death.

Kulkarni HS, Elvington ML, Perng YC, Liszewski MK, Byers DE, Farkouh C, Yusen RD, Lenschow DJ, Brody SL, Atkinson JP.

Am J Respir Cell Mol Biol. 2019 Feb;60(2):144-157. doi: 10.1165/rcmb.2017-0405OC.

PMID:
30156437
11.

Blood Exposure Causes Ventricular Zone Disruption and Glial Activation In Vitro.

Castaneyra-Ruiz L, Morales DM, McAllister JP, Brody SL, Isaacs AM, Strahle JM, Dahiya SM, Limbrick DD.

J Neuropathol Exp Neurol. 2018 Sep 1;77(9):803-813. doi: 10.1093/jnen/nly058.

12.

Quantifying Ciliary Dynamics during Assembly Reveals Stepwise Waveform Maturation in Airway Cells.

Oltean A, Schaffer AJ, Bayly PV, Brody SL.

Am J Respir Cell Mol Biol. 2018 Oct;59(4):511-522. doi: 10.1165/rcmb.2017-0436OC.

13.

Visualization of Monocytic Cells in Regressing Atherosclerotic Plaques by Intravital 2-Photon and Positron Emission Tomography-Based Imaging-Brief Report.

Li W, Luehmann HP, Hsiao HM, Tanaka S, Higashikubo R, Gauthier JM, Sultan D, Lavine KJ, Brody SL, Gelman AE, Gropler RJ, Liu Y, Kreisel D.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1030-1036. doi: 10.1161/ATVBAHA.117.310517. Epub 2018 Mar 22.

14.

Development of Fully Degradable Phosphonium-Functionalized Amphiphilic Diblock Copolymers for Nucleic Acids Delivery.

Borguet YP, Khan S, Noel A, Gunsten SP, Brody SL, Elsabahy M, Wooley KL.

Biomacromolecules. 2018 Apr 9;19(4):1212-1222. doi: 10.1021/acs.biomac.8b00069. Epub 2018 Mar 11.

15.

Establishment of the early cilia preassembly protein complex during motile ciliogenesis.

Horani A, Ustione A, Huang T, Firth AL, Pan J, Gunsten SP, Haspel JA, Piston DW, Brody SL.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1221-E1228. doi: 10.1073/pnas.1715915115. Epub 2018 Jan 22.

16.

The complement system in the airway epithelium: An overlooked host defense mechanism and therapeutic target?

Kulkarni HS, Liszewski MK, Brody SL, Atkinson JP.

J Allergy Clin Immunol. 2018 May;141(5):1582-1586.e1. doi: 10.1016/j.jaci.2017.11.046. Epub 2018 Jan 12. Review. No abstract available.

17.

Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation.

Dickinson JD, Sweeter JM, Warren KJ, Ahmad IM, De Deken X, Zimmerman MC, Brody SL.

Redox Biol. 2018 Apr;14:272-284. doi: 10.1016/j.redox.2017.09.013. Epub 2017 Sep 22.

18.

17β-Estradiol Dysregulates Innate Immune Responses to Pseudomonas aeruginosa Respiratory Infection and Is Modulated by Estrogen Receptor Antagonism.

Abid S, Xie S, Bose M, Shaul PW, Terada LS, Brody SL, Thomas PJ, Katzenellenbogen JA, Kim SH, Greenberg DE, Jain R.

Infect Immun. 2017 Sep 20;85(10). pii: e00422-17. doi: 10.1128/IAI.00422-17. Print 2017 Oct.

19.

Harnessing TGF-β and BMP signaling for expansion of p63-positive epithelial stem cells.

Brody SL, Kaiko GE.

Stem Cell Investig. 2016 Nov 15;3:82. doi: 10.21037/sci.2016.10.13. eCollection 2016. No abstract available.

20.

PET-based Imaging of Chemokine Receptor 2 in Experimental and Disease-related Lung Inflammation.

Liu Y, Gunsten SP, Sultan DH, Luehmann HP, Zhao Y, Blackwell TS, Bollermann-Nowlis Z, Pan JH, Byers DE, Atkinson JJ, Kreisel D, Holtzman MJ, Gropler RJ, Combadiere C, Brody SL.

Radiology. 2017 Jun;283(3):758-768. doi: 10.1148/radiol.2016161409. Epub 2017 Jan 3.

21.

Noninvasive Imaging of CCR2+ Cells in Ischemia-Reperfusion Injury After Lung Transplantation.

Liu Y, Li W, Luehmann HP, Zhao Y, Detering L, Sultan DH, Hsiao HM, Krupnick AS, Gelman AE, Combadiere C, Gropler RJ, Brody SL, Kreisel D.

Am J Transplant. 2016 Oct;16(10):3016-3023. doi: 10.1111/ajt.13907. Epub 2016 Jul 14.

22.

In vivo fate tracking of degradable nanoparticles for lung gene transfer using PET and Ĉerenkov imaging.

Black KC, Ibricevic A, Gunsten SP, Flores JA, Gustafson TP, Raymond JE, Samarajeewa S, Shrestha R, Felder SE, Cai T, Shen Y, Löbs AK, Zhegalova N, Sultan DH, Berezin M, Wooley KL, Liu Y, Brody SL.

Biomaterials. 2016 Aug;98:53-63. doi: 10.1016/j.biomaterials.2016.04.040. Epub 2016 May 3.

23.

p300/β-Catenin Interactions Regulate Adult Progenitor Cell Differentiation Downstream of WNT5a/Protein Kinase C (PKC).

Rieger ME, Zhou B, Solomon N, Sunohara M, Li C, Nguyen C, Liu Y, Pan JH, Minoo P, Crandall ED, Brody SL, Kahn M, Borok Z.

J Biol Chem. 2016 Mar 18;291(12):6569-82. doi: 10.1074/jbc.M115.706416. Epub 2016 Feb 1.

24.

Genetics and biology of primary ciliary dyskinesia.

Horani A, Ferkol TW, Dutcher SK, Brody SL.

Paediatr Respir Rev. 2016 Mar;18:18-24. doi: 10.1016/j.prrv.2015.09.001. Epub 2015 Sep 11. Review.

25.

Ex Vivo and In Vivo Lentivirus-Mediated Transduction of Airway Epithelial Progenitor Cells.

Leoni G, Wasowicz MY, Chan M, Meng C, Farley R, Brody SL, Inoue M, Hasegawa M, Alton EW, Griesenbach U.

Curr Gene Ther. 2015;15(6):581-90.

26.

IL13 activates autophagy to regulate secretion in airway epithelial cells.

Dickinson JD, Alevy Y, Malvin NP, Patel KK, Gunsten SP, Holtzman MJ, Stappenbeck TS, Brody SL.

Autophagy. 2016;12(2):397-409. doi: 10.1080/15548627.2015.1056967. Epub 2015 Jun 10.

27.

Visualization of pulmonary clearance mechanisms via noninvasive optical imaging validated by near-infrared flow cytometry.

Zhou H, Gunsten SP, Zhegalova NG, Bloch S, Achilefu S, Christopher Holley J, Schweppe D, Akers W, Brody SL, Eades WC, Berezin MY.

Cytometry A. 2015 May;87(5):419-27. doi: 10.1002/cyto.a.22658. Epub 2015 Mar 23.

28.

DAP12 expression in lung macrophages mediates ischemia/reperfusion injury by promoting neutrophil extravasation.

Spahn JH, Li W, Bribriesco AC, Liu J, Shen H, Ibricevic A, Pan JH, Zinselmeyer BH, Brody SL, Goldstein DR, Krupnick AS, Gelman AE, Miller MJ, Kreisel D.

J Immunol. 2015 Apr 15;194(8):4039-48. doi: 10.4049/jimmunol.1401415. Epub 2015 Mar 11.

29.

Imaging pulmonary inducible nitric oxide synthase expression with PET.

Huang HJ, Isakow W, Byers DE, Engle JT, Griffin EA, Kemp D, Brody SL, Gropler RJ, Miller JP, Chu W, Zhou D, Pierce RA, Castro M, Mach RH, Chen DL.

J Nucl Med. 2015 Jan;56(1):76-81. doi: 10.2967/jnumed.114.146381. Epub 2014 Dec 18.

30.

Interferon response and respiratory virus control are preserved in bronchial epithelial cells in asthma.

Patel DA, You Y, Huang G, Byers DE, Kim HJ, Agapov E, Moore ML, Peebles RS Jr, Castro M, Sumino K, Shifren A, Brody SL, Holtzman MJ.

J Allergy Clin Immunol. 2014 Dec;134(6):1402-1412.e7. doi: 10.1016/j.jaci.2014.07.013. Epub 2014 Sep 9.

31.

Myb permits multilineage airway epithelial cell differentiation.

Pan JH, Adair-Kirk TL, Patel AC, Huang T, Yozamp NS, Xu J, Reddy EP, Byers DE, Pierce RA, Holtzman MJ, Brody SL.

Stem Cells. 2014 Dec;32(12):3245-56. doi: 10.1002/stem.1814.

32.

Response to Snijders et al.

Horani A, Brody SL, Ferkol TW.

Pediatr Res. 2014 Sep;76(3):322. doi: 10.1038/pr.2014.80. Epub 2014 Jun 16. No abstract available.

PMID:
24933009
33.

Antisense peptide nucleic acid-functionalized cationic nanocomplex for in vivo mRNA detection.

Shen Y, Shrestha R, Ibricevic A, Gunsten SP, Welch MJ, Wooley KL, Brody SL, Taylor JS, Liu Y.

Interface Focus. 2013 Jun 6;3(3):20120059. doi: 10.1098/rsfs.2012.0059.

34.

Picking up speed: advances in the genetics of primary ciliary dyskinesia.

Horani A, Brody SL, Ferkol TW.

Pediatr Res. 2014 Jan;75(1-2):158-64. doi: 10.1038/pr.2013.200. Epub 2013 Nov 5. Review.

35.

Chemosensory functions for pulmonary neuroendocrine cells.

Gu X, Karp PH, Brody SL, Pierce RA, Welsh MJ, Holtzman MJ, Ben-Shahar Y.

Am J Respir Cell Mol Biol. 2014 Mar;50(3):637-46. doi: 10.1165/rcmb.2013-0199OC.

36.

CCDC65 mutation causes primary ciliary dyskinesia with normal ultrastructure and hyperkinetic cilia.

Horani A, Brody SL, Ferkol TW, Shoseyov D, Wasserman MG, Ta-shma A, Wilson KS, Bayly PV, Amirav I, Cohen-Cymberknoh M, Dutcher SK, Elpeleg O, Kerem E.

PLoS One. 2013 Aug 26;8(8):e72299. doi: 10.1371/journal.pone.0072299. eCollection 2013.

37.

Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease.

Byers DE, Alexander-Brett J, Patel AC, Agapov E, Dang-Vu G, Jin X, Wu K, You Y, Alevy Y, Girard JP, Stappenbeck TS, Patterson GA, Pierce RA, Brody SL, Holtzman MJ.

J Clin Invest. 2013 Sep;123(9):3967-82. doi: 10.1172/JCI65570. Epub 2013 Aug 15. Erratum in: J Clin Invest. 2013 Dec 2;123(12):5410.

38.

Applications of mouse airway epithelial cell culture for asthma research.

Horani A, Dickinson JD, Brody SL.

Methods Mol Biol. 2013;1032:91-107. doi: 10.1007/978-1-62703-496-8_7.

PMID:
23943446
39.

Synthesis, characterization, and in vivo efficacy of shell cross-linked nanoparticle formulations carrying silver antimicrobials as aerosolized therapeutics.

Shah PN, Lin LY, Smolen JA, Tagaev JA, Gunsten SP, Han DS, Heo GS, Li Y, Zhang F, Zhang S, Wright BD, Panzner MJ, Youngs WJ, Brody SL, Wooley KL, Cannon CL.

ACS Nano. 2013 Jun 25;7(6):4977-87. doi: 10.1021/nn400322f. Epub 2013 Jun 4.

40.

Rho-associated protein kinase inhibition enhances airway epithelial Basal-cell proliferation and lentivirus transduction.

Horani A, Nath A, Wasserman MG, Huang T, Brody SL.

Am J Respir Cell Mol Biol. 2013 Sep;49(3):341-7. doi: 10.1165/rcmb.2013-0046TE.

41.

Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signaling.

Li A, Chan B, Felix JC, Xing Y, Li M, Brody SL, Borok Z, Li C, Minoo P.

PLoS One. 2013 Apr 30;8(4):e62215. doi: 10.1371/journal.pone.0062215. Print 2013.

42.

LRRC6 mutation causes primary ciliary dyskinesia with dynein arm defects.

Horani A, Ferkol TW, Shoseyov D, Wasserman MG, Oren YS, Kerem B, Amirav I, Cohen-Cymberknoh M, Dutcher SK, Brody SL, Elpeleg O, Kerem E.

PLoS One. 2013;8(3):e59436. doi: 10.1371/journal.pone.0059436. Epub 2013 Mar 19.

43.

Analysis of ciliogenesis in primary culture mouse tracheal epithelial cells.

Vladar EK, Brody SL.

Methods Enzymol. 2013;525:285-309. doi: 10.1016/B978-0-12-397944-5.00014-6.

PMID:
23522475
44.

Degradable cationic shell cross-linked knedel-like nanoparticles: synthesis, degradation, nucleic acid binding, and in vitro evaluation.

Samarajeewa S, Ibricevic A, Gunsten SP, Shrestha R, Elsabahy M, Brody SL, Wooley KL.

Biomacromolecules. 2013 Apr 8;14(4):1018-27. doi: 10.1021/bm3018774. Epub 2013 Mar 19.

45.

PEGylation of cationic, shell-crosslinked-knedel-like nanoparticles modulates inflammation and enhances cellular uptake in the lung.

Ibricevic A, Guntsen SP, Zhang K, Shrestha R, Liu Y, Sun JY, Welch MJ, Wooley KL, Brody SL.

Nanomedicine. 2013 Oct;9(7):912-22. doi: 10.1016/j.nano.2013.02.006. Epub 2013 Feb 27.

46.

IL-17A induces signal transducers and activators of transcription-6-independent airway mucous cell metaplasia.

Newcomb DC, Boswell MG, Sherrill TP, Polosukhin VV, Boyd KL, Goleniewska K, Brody SL, Kolls JK, Adler KB, Peebles RS Jr.

Am J Respir Cell Mol Biol. 2013 Jun;48(6):711-6. doi: 10.1165/rcmb.2013-0017OC.

47.

Culture and differentiation of mouse tracheal epithelial cells.

You Y, Brody SL.

Methods Mol Biol. 2013;945:123-43. doi: 10.1007/978-1-62703-125-7_9.

PMID:
23097105
48.

Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia.

Horani A, Druley TE, Zariwala MA, Patel AC, Levinson BT, Van Arendonk LG, Thornton KC, Giacalone JC, Albee AJ, Wilson KS, Turner EH, Nickerson DA, Shendure J, Bayly PV, Leigh MW, Knowles MR, Brody SL, Dutcher SK, Ferkol TW.

Am J Hum Genet. 2012 Oct 5;91(4):685-93. doi: 10.1016/j.ajhg.2012.08.022.

49.

Lung transplant acceptance is facilitated by early events in the graft and is associated with lymphoid neogenesis.

Li W, Bribriesco AC, Nava RG, Brescia AA, Ibricevic A, Spahn JH, Brody SL, Ritter JH, Gelman AE, Krupnick AS, Miller MJ, Kreisel D.

Mucosal Immunol. 2012 Sep;5(5):544-54. doi: 10.1038/mi.2012.30. Epub 2012 May 2.

50.

Sensory functions of motile cilia and implication for bronchiectasis.

Jain R, Javidan-Nejad C, Alexander-Brett J, Horani A, Cabellon MC, Walter MJ, Brody SL.

Front Biosci (Schol Ed). 2012 Jan 1;4:1088-98. Review.

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