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Items: 1 to 50 of 120

1.

Derivation of a bronchial genomic classifier for lung cancer in a prospective study of patients undergoing diagnostic bronchoscopy.

Whitney DH, Elashoff MR, Porta-Smith K, Gower AC, Vachani A, Ferguson JS, Silvestri GA, Brody JS, Lenburg ME, Spira A.

BMC Med Genomics. 2015 May 6;8:18. doi: 10.1186/s12920-015-0091-3.

2.

Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention.

Kathuria H, Gesthalter Y, Spira A, Brody JS, Steiling K.

Cancers (Basel). 2014 May 16;6(2):1157-79. doi: 10.3390/cancers6021157.

3.

The Red journal at 25. A perspective from the founding editors.

Senior RM, Brody JS, Williams MC.

Am J Respir Cell Mol Biol. 2014 May;50(5):840-1. doi: 10.1165/rcmb.2014-0105ED. No abstract available.

PMID:
24783953
4.

The promise and problems of e-cigarettes.

Brody JS.

Am J Respir Crit Care Med. 2014 Feb 15;189(4):379-80. doi: 10.1164/rccm.201312-2263ED. No abstract available.

PMID:
24528311
5.

Transcriptome alterations induced by cigarette smoke.

Brody JS.

Int J Cancer. 2012 Dec 15;131(12):2754-62. doi: 10.1002/ijc.27829. Epub 2012 Oct 5. Review.

6.

Interaction of cigarette exposure and airway epithelial cell gene expression.

Brody JS, Steiling K.

Annu Rev Physiol. 2011;73:437-56. doi: 10.1146/annurev-physiol-012110-142219. Review.

PMID:
21090967
7.

Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers.

Steiling K, Kadar AY, Bergerat A, Flanigon J, Sridhar S, Shah V, Ahmad QR, Brody JS, Lenburg ME, Steffen M, Spira A.

PLoS One. 2009;4(4):e5043. doi: 10.1371/journal.pone.0005043. Epub 2009 Apr 9.

8.

MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium.

Schembri F, Sridhar S, Perdomo C, Gustafson AM, Zhang X, Ergun A, Lu J, Liu G, Zhang X, Bowers J, Vaziri C, Ott K, Sensinger K, Collins JJ, Brody JS, Getts R, Lenburg ME, Spira A.

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2319-24. doi: 10.1073/pnas.0806383106. Epub 2009 Jan 23.

9.

The field of tissue injury in the lung and airway.

Steiling K, Ryan J, Brody JS, Spira A.

Cancer Prev Res (Phila). 2008 Nov;1(6):396-403. doi: 10.1158/1940-6207.CAPR-08-0174. Review.

10.

Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium.

Sridhar S, Schembri F, Zeskind J, Shah V, Gustafson AM, Steiling K, Liu G, Dumas YM, Zhang X, Brody JS, Lenburg ME, Spira A.

BMC Genomics. 2008 May 30;9:259. doi: 10.1186/1471-2164-9-259.

11.

Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression.

Beane J, Sebastiani P, Liu G, Brody JS, Lenburg ME, Spira A.

Genome Biol. 2007;8(9):R201.

12.

Microsensor arrays for saliva diagnostics.

Walt DR, Blicharz TM, Hayman RB, Rissin DM, Bowden M, Siqueira WL, Helmerhorst EJ, Grand-Pierre N, Oppenheim FG, Bhatia JS, Little FF, Brody JS.

Ann N Y Acad Sci. 2007 Mar;1098:389-400.

PMID:
17435144
13.

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer.

Spira A, Beane JE, Shah V, Steiling K, Liu G, Schembri F, Gilman S, Dumas YM, Calner P, Sebastiani P, Sridhar S, Beamis J, Lamb C, Anderson T, Gerry N, Keane J, Lenburg ME, Brody JS.

Nat Med. 2007 Mar;13(3):361-6. Epub 2007 Mar 4.

PMID:
17334370
14.

State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer.

Brody JS, Spira A.

Proc Am Thorac Soc. 2006 Aug;3(6):535-7. Review.

PMID:
16921139
15.

SIEGE: Smoking Induced Epithelial Gene Expression Database.

Shah V, Sridhar S, Beane J, Brody JS, Spira A.

Nucleic Acids Res. 2005 Jan 1;33(Database issue):D573-9.

16.

Gene expression profiling of human lung tissue from smokers with severe emphysema.

Spira A, Beane J, Pinto-Plata V, Kadar A, Liu G, Shah V, Celli B, Brody JS.

Am J Respir Cell Mol Biol. 2004 Dec;31(6):601-10. Epub 2004 Sep 16.

PMID:
15374838
17.

Effects of cigarette smoke on the human airway epithelial cell transcriptome.

Spira A, Beane J, Shah V, Liu G, Schembri F, Yang X, Palma J, Brody JS.

Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10143-8. Epub 2004 Jun 21.

18.

Impact of cigarette smoke on the normal airway transcriptome.

Spira A, Schembri F, Beane J, Shah V, Liu G, Brody JS.

Chest. 2004 May;125(5 Suppl):115S. No abstract available.

PMID:
15136455
19.

Noninvasive method for obtaining RNA from buccal mucosa epithelial cells for gene expression profiling.

Spira A, Beane J, Schembri F, Liu G, Ding C, Gilman S, Yang X, Cantor C, Brody JS.

Biotechniques. 2004 Mar;36(3):484-7. No abstract available.

20.

"What we've got here is a failure to communicate".

Brody JS.

Am J Respir Crit Care Med. 2003 Aug 15;168(4):415-6. No abstract available.

PMID:
12912733
21.

The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor.

Kim H, Xu GL, Borczuk AC, Busch S, Filmus J, Capurro M, Brody JS, Lange J, D'Armiento JM, Rothman PB, Powell CA.

Am J Respir Cell Mol Biol. 2003 Dec;29(6):694-701. Epub 2003 Jun 19.

PMID:
12816733
22.

Gene expression in lung adenocarcinomas of smokers and nonsmokers.

Powell CA, Spira A, Derti A, DeLisi C, Liu G, Borczuk A, Busch S, Sahasrabudhe S, Chen Y, Sugarbaker D, Bueno R, Richards WG, Brody JS.

Am J Respir Cell Mol Biol. 2003 Aug;29(2):157-62. Epub 2003 Feb 21.

PMID:
12600827
23.

Patterns of allelic loss differ in lung adenocarcinomas of smokers and nonsmokers.

Powell CA, Bueno R, Borczuk AC, Caracta CF, Richards WG, Sugarbaker DJ, Brody JS.

Lung Cancer. 2003 Jan;39(1):23-9.

PMID:
12499090
24.

Oligonucleotide microarray analysis of lung adenocarcinoma in smokers and nonsmokers identifies GPC3 as a potential lung tumor suppressor.

Powell CA, Xu G, Filmus J, Busch S, Brody JS, Rothman PB.

Chest. 2002 Mar;121(3 Suppl):6S-7S. No abstract available.

PMID:
11893651
25.

Retinoblastoma protein complexes with C/EBP proteins and activates C/EBP-mediated transcription.

Charles A, Tang X, Crouch E, Brody JS, Xiao ZX.

J Cell Biochem. 2001 Aug 21-Sep 5;83(3):414-25.

PMID:
11596110
26.

Loss of heterozygosity in epithelial cells obtained by bronchial brushing: clinical utility in lung cancer.

Powell CA, Klares S, O'Connor G, Brody JS.

Clin Cancer Res. 1999 Aug;5(8):2025-34.

27.
28.

Atrial natriuretic peptide modulates alveolar type 2 cell adenylyl and guanylyl cyclases and inhibits surfactant secretion.

Panchenko MP, Joyce-Brady M, Starikova MG, Oakes SM, Adachi R, Brody JS, Dickey BF.

Biochim Biophys Acta. 1998 May 27;1403(1):115-25.

29.

FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium.

Cardoso WV, Itoh A, Nogawa H, Mason I, Brody JS.

Dev Dyn. 1997 Mar;208(3):398-405.

30.

Epithelial marker genes are expressed in cultured embryonic rat lung and in vivo with similar spatial and temporal patterns.

Meneghetti A, Cardoso WV, Brody JS, Williams MC.

J Histochem Cytochem. 1996 Oct;44(10):1173-82.

PMID:
8813083
31.

Retinoic acid alters the expression of pattern-related genes in the developing rat lung.

Cardoso WV, Mitsialis SA, Brody JS, Williams MC.

Dev Dyn. 1996 Sep;207(1):47-59.

32.

Type I receptor serine-threonine kinase preferentially expressed in pulmonary blood vessels.

Panchenko MP, Williams MC, Brody JS, Yu Q.

Am J Physiol. 1996 Apr;270(4 Pt 1):L547-58.

PMID:
8928814
33.
34.

Expression of insulin-like growth factor receptors 1 and 2 in the developing lung and their relation to epithelial cell differentiation.

Maitre B, Clement A, Williams MC, Brody JS.

Am J Respir Cell Mol Biol. 1995 Sep;13(3):262-70.

PMID:
7654382
35.

Retinoic acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro.

Cardoso WV, Williams MC, Mitsialis SA, Joyce-Brady M, Rishi AK, Brody JS.

Am J Respir Cell Mol Biol. 1995 May;12(5):464-76.

PMID:
7742011
36.

Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors.

Itoh A, Levinson SF, Morita T, Kourembanas S, Brody JS, Mitsialis SA.

Cell Mol Biol Res. 1995;41(3):147-54.

PMID:
8589754
37.

Cloning, characterization, and development expression of a rat lung alveolar type I cell gene in embryonic endodermal and neural derivatives.

Rishi AK, Joyce-Brady M, Fisher J, Dobbs LG, Floros J, VanderSpek J, Brody JS, Williams MC.

Dev Biol. 1995 Jan;167(1):294-306.

38.

Insulin-like growth factors, their binding proteins, and transforming growth factor-beta 1 in oxidant-arrested lung alveolar epithelial cells.

Cazals V, Mouhieddine B, Maitre B, Le Bouc Y, Chadelat K, Brody JS, Clement A.

J Biol Chem. 1994 May 13;269(19):14111-7.

39.

Type I collagen formation in rat type II alveolar cells immortalised by viral gene products.

Matsui R, Goldstein RH, Mihal K, Brody JS, Steele MP, Fine A.

Thorax. 1994 Mar;49(3):201-6.

40.

Effect of floating a gel matrix on mucin release in cultured airway epithelial cells.

Kim KC, Zheng QX, Brody JS.

J Cell Physiol. 1993 Sep;156(3):480-6.

PMID:
8360255
41.
42.

A rat alveolar type II cell line developed by adenovirus 12SE1A gene transfer.

Steele MP, Levine RA, Joyce-Brady M, Brody JS.

Am J Respir Cell Mol Biol. 1992 Jan;6(1):50-6.

PMID:
1728294
43.

Pulmonary alveolar epithelial cell differentiation.

Brody JS, Williams MC.

Annu Rev Physiol. 1992;54:351-71. Review. No abstract available.

PMID:
1562179
44.

SV40T-immortalized lung alveolar epithelial cells display post-transcriptional regulation of proliferation-related genes.

Clement A, Steele MP, Brody JS, Riedel N.

Exp Cell Res. 1991 Oct;196(2):198-205.

PMID:
1716583
45.

Lung development: past, present and future.

Brody JS.

Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Jan;29(1):4-6. No abstract available.

PMID:
2041256
46.

Growth-related gene expression in type 2 alveolar epithelial cells.

Clement A, Steele M, Brody JS, Riedel N.

Am Rev Respir Dis. 1990 Dec;142(6 Pt 2):S60-2.

PMID:
2252276
47.

Serum accelerates the loss of type II cell differentiation in vitro.

Paine R 3rd, Joyce-Brady M, Clement A, Brody JS.

Am J Respir Cell Mol Biol. 1990 Oct;3(4):311-23.

PMID:
1698400
48.

[3H]thymidine incorporation does not correlate with growth state in cultured alveolar type II cells.

Clement A, Riedel N, Brody JS.

Am J Respir Cell Mol Biol. 1990 Aug;3(2):159-64.

PMID:
2378750
49.

Ontogeny of pulmonary alveolar epithelial markers of differentiation.

Joyce-Brady MF, Brody JS.

Dev Biol. 1990 Feb;137(2):331-48.

PMID:
2303166

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