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Items: 1 to 50 of 231

1.

Nestin+NG2+ Cells Form a Reserve Stem Cell Population in the Mouse Prostate.

Hanoun M, Arnal-Estapé A, Maryanovich M, Zahalka AH, Bergren SK, Chua CW, Leftin A, Brodin PN, Shen MM, Guha C, Frenette PS.

Stem Cell Reports. 2019 Jun 11;12(6):1201-1211. doi: 10.1016/j.stemcr.2019.04.019. Epub 2019 May 23.

PMID:
31130357
2.

Automated Cell Processing for Mass Cytometry Experiments.

Mikes J, Olin A, Lakshmikanth T, Chen Y, Brodin P.

Methods Mol Biol. 2019;1989:111-123. doi: 10.1007/978-1-4939-9454-0_8.

PMID:
31077102
3.

A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation.

Pastor A, Machelart A, Li X, Willand N, Baulard A, Brodin P, Gref R, Desmaële D.

Org Biomol Chem. 2019 May 28;17(20):5129-5137. doi: 10.1039/c9ob00680j. Epub 2019 May 10.

PMID:
31073555
4.

Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters.

Babonneau J, Bréard D, Reynaert ML, Marion E, Guilet D, Saint André JP, Croué A, Brodin P, Richomme P, Marsollier L.

Front Pharmacol. 2019 Apr 12;10:378. doi: 10.3389/fphar.2019.00378. eCollection 2019.

5.

B cell profiling in malaria reveals expansion and remodelling of CD11c+ B cell subsets.

Sundling C, Rönnberg C, Yman V, Asghar M, Jahnmatz P, Lakshmikanth T, Chen Y, Mikes J, Forsell MN, Sondén K, Achour A, Brodin P, Persson KE, Färnert A.

JCI Insight. 2019 Apr 2;5. pii: 126492. doi: 10.1172/jci.insight.126492.

6.

Leucocytosis is associated with retinopathy of prematurity in extremely preterm infants.

Lundgren P, Klevebro S, Brodin P, Smith LEH, Hallberg B, Hellström A.

Acta Paediatr. 2019 Mar 28. doi: 10.1111/apa.14798. [Epub ahead of print]

PMID:
30920014
7.

The repertoire of maternal anti-viral antibodies in human newborns.

Pou C, Nkulikiyimfura D, Henckel E, Olin A, Lakshmikanth T, Mikes J, Wang J, Chen Y, Bernhardsson AK, Gustafsson A, Bohlin K, Brodin P.

Nat Med. 2019 Apr;25(4):591-596. doi: 10.1038/s41591-019-0392-8. Epub 2019 Mar 18.

PMID:
30886409
8.

Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication.

Sahuc ME, Sahli R, Rivière C, Pène V, Lavie M, Vandeputte A, Brodin P, Rosenberg AR, Dubuisson J, Ksouri R, Rouillé Y, Sahpaz S, Séron K.

J Virol. 2019 May 1;93(10). pii: e02009-18. doi: 10.1128/JVI.02009-18. Print 2019 May 15.

PMID:
30842319
9.

Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis.

Machelart A, Salzano G, Li X, Demars A, Debrie AS, Menendez-Miranda M, Pancani E, Jouny S, Hoffmann E, Deboosere N, Belhaouane I, Rouanet C, Simar S, Talahari S, Giannini V, Villemagne B, Flipo M, Brosch R, Nesslany F, Deprez B, Muraille E, Locht C, Baulard AR, Willand N, Majlessi L, Gref R, Brodin P.

ACS Nano. 2019 Apr 23;13(4):3992-4007. doi: 10.1021/acsnano.8b07902. Epub 2019 Mar 8.

PMID:
30822386
10.

Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS Stimulation.

Pauwels AM, Härtlova A, Peltier J, Driege Y, Baudelet G, Brodin P, Trost M, Beyaert R, Hoffmann E.

Mol Cell Proteomics. 2019 May;18(5):909-922. doi: 10.1074/mcp.RA119.001316. Epub 2019 Feb 26.

PMID:
30808727
11.

Mass cytometry identifies distinct CD4+ T cell clusters distinguishing HIV-1-infected patients according to antiretroviral therapy initiation.

Bekele Y, Lakshmikanth T, Chen Y, Mikes J, Nasi A, Petkov S, Hejdeman B, Brodin P, Chiodi F.

JCI Insight. 2019 Feb 7;4(3). pii: 125442. doi: 10.1172/jci.insight.125442. [Epub ahead of print]

12.

Mitochondrial Dynamics and Activity in Legionella-Infected Cells.

Song OR, Brodin P, Buchrieser C, Escoll P.

Methods Mol Biol. 2019;1921:205-220. doi: 10.1007/978-1-4939-9048-1_13.

PMID:
30694494
13.

Systems-Level Immune Monitoring by Mass Cytometry.

Lakshmikanth T, Brodin P.

Methods Mol Biol. 2019;1913:33-48. doi: 10.1007/978-1-4939-8979-9_3.

PMID:
30666597
14.

Systems-level patterns emerge.

Brodin P.

Nat Rev Immunol. 2019 Feb;19(2):87-88. doi: 10.1038/s41577-018-0106-3. No abstract available.

PMID:
30604773
15.

B cell alterations during BAFF inhibition with belimumab in SLE.

Ramsköld D, Parodis I, Lakshmikanth T, Sippl N, Khademi M, Chen Y, Zickert A, Mikeš J, Achour A, Amara K, Piehl F, Brodin P, Gunnarsson I, Malmström V.

EBioMedicine. 2019 Feb;40:517-527. doi: 10.1016/j.ebiom.2018.12.035. Epub 2018 Dec 26.

16.

Theaflavins, polyphenols of black tea, inhibit entry of hepatitis C virus in cell culture.

Chowdhury P, Sahuc ME, Rouillé Y, Rivière C, Bonneau N, Vandeputte A, Brodin P, Goswami M, Bandyopadhyay T, Dubuisson J, Séron K.

PLoS One. 2018 Nov 28;13(11):e0198226. doi: 10.1371/journal.pone.0198226. eCollection 2018.

17.

Effect of CTLA4-Ig (abatacept) treatment on T cells and B cells in peripheral blood of patients with polymyositis and dermatomyositis.

Tang Q, Ramsköld D, Krystufkova O, Mann HF, Wick C, Dastmalchi M, Lakshmikanth T, Chen Y, Mikes J, Alexanderson H, Achour A, Brodin P, Vencovsky J, Lundberg IE, Malmström V.

Scand J Immunol. 2019 Jan;89(1):e12732. doi: 10.1111/sji.12732. Epub 2018 Dec 9.

PMID:
30451307
18.

The biology of the cell - insights from mass cytometry.

Brodin P.

FEBS J. 2019 Apr;286(8):1514-1522. doi: 10.1111/febs.14693. Epub 2018 Nov 26. Review.

PMID:
30390411
19.

Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria.

Raze D, Verwaerde C, Deloison G, Werkmeister E, Coupin B, Loyens M, Brodin P, Rouanet C, Locht C.

Front Microbiol. 2018 Sep 24;9:2258. doi: 10.3389/fmicb.2018.02258. eCollection 2018.

20.

Continuous Immune Cell Differentiation Inferred From Single-Cell Measurements Following Allogeneic Stem Cell Transplantation.

Chen Y, Lakshmikanth T, Olin A, Mikes J, Remberger M, Brodin P.

Front Mol Biosci. 2018 Sep 12;5:81. doi: 10.3389/fmolb.2018.00081. eCollection 2018.

21.

Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis.

Nguyen PC, Delorme V, Bénarouche A, Guy A, Landry V, Audebert S, Pophillat M, Camoin L, Crauste C, Galano JM, Durand T, Brodin P, Canaan S, Cavalier JF.

Bioorg Chem. 2018 Dec;81:414-424. doi: 10.1016/j.bioorg.2018.08.025. Epub 2018 Aug 29.

PMID:
30212765
22.

The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.

Mori G, Orena BS, Franch C, Mitchenall LA, Godbole AA, Rodrigues L, Aguilar-Pérez C, Zemanová J, Huszár S, Forbak M, Lane TR, Sabbah M, Deboosere N, Frita R, Vandeputte A, Hoffmann E, Russo R, Connell N, Veilleux C, Jha RK, Kumar P, Freundlich JS, Brodin P, Aínsa JA, Nagaraja V, Maxwell A, Mikušová K, Pasca MR, Ekins S.

Tuberculosis (Edinb). 2018 Sep;112:98-109. doi: 10.1016/j.tube.2018.08.004. Epub 2018 Aug 11.

PMID:
30205975
23.

Stereotypic Immune System Development in Newborn Children.

Olin A, Henckel E, Chen Y, Lakshmikanth T, Pou C, Mikes J, Gustafsson A, Bernhardsson AK, Zhang C, Bohlin K, Brodin P.

Cell. 2018 Aug 23;174(5):1277-1292.e14. doi: 10.1016/j.cell.2018.06.045.

24.

Synergy between Circular Bacteriocin AS-48 and Ethambutol against Mycobacterium tuberculosis.

Aguilar-Pérez C, Gracia B, Rodrigues L, Vitoria A, Cebrián R, Deboosère N, Song OR, Brodin P, Maqueda M, Aínsa JA.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00359-18. doi: 10.1128/AAC.00359-18. Print 2018 Sep.

25.

Publisher Correction: Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.

Costa-Gouveia J, Pancani E, Jouny S, Machelart A, Delorme V, Salzano G, Iantomasi R, Piveteau C, Queval CJ, Song OR, Flipo M, Deprez B, Saint-André JP, Hureaux J, Majlessi L, Willand N, Baulard A, Brodin P, Gref R.

Sci Rep. 2018 May 10;8(1):7596. doi: 10.1038/s41598-018-25177-2.

26.

Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors.

Sayes F, Blanc C, Ates LS, Deboosere N, Orgeur M, Le Chevalier F, Gröschel MI, Frigui W, Song OR, Lo-Man R, Brossier F, Sougakoff W, Bottai D, Brodin P, Charneau P, Brosch R, Majlessi L.

Cell Rep. 2018 Apr 24;23(4):1072-1084. doi: 10.1016/j.celrep.2018.03.125.

27.

Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry.

Riva L, Song OR, Prentoe J, Helle F, L'homme L, Gattolliat CH, Vandeputte A, Fénéant L, Belouzard S, Baumert TF, Asselah T, Bukh J, Brodin P, Cocquerel L, Rouillé Y, Dubuisson J.

J Virol. 2018 Apr 27;92(10). pii: e01982-17. doi: 10.1128/JVI.01982-17. Print 2018 May 15.

28.

Rebooting Human Immunology.

Davis MM, Brodin P.

Annu Rev Immunol. 2018 Apr 26;36:843-864. doi: 10.1146/annurev-immunol-042617-053206. Epub 2018 Feb 28.

PMID:
29490162
29.

Proteomics of Mycobacterium Infection: Moving towards a Better Understanding of Pathogen-Driven Immunomodulation.

Hoffmann E, Machelart A, Song OR, Brodin P.

Front Immunol. 2018 Jan 30;9:86. doi: 10.3389/fimmu.2018.00086. eCollection 2018. Review.

30.

Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation.

Agudelo LZ, Ferreira DMS, Cervenka I, Bryzgalova G, Dadvar S, Jannig PR, Pettersson-Klein AT, Lakshmikanth T, Sustarsic EG, Porsmyr-Palmertz M, Correia JC, Izadi M, Martínez-Redondo V, Ueland PM, Midttun Ø, Gerhart-Hines Z, Brodin P, Pereira T, Berggren PO, Ruas JL.

Cell Metab. 2018 Feb 6;27(2):378-392.e5. doi: 10.1016/j.cmet.2018.01.004.

31.

Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains.

Ju CH, Blum LK, Kongpachith S, Lingampalli N, Mao R, Brodin P, Dekker CL, Davis MM, Robinson WH.

Clin Immunol. 2018 Aug;193:70-79. doi: 10.1016/j.clim.2018.01.011. Epub 2018 Feb 2.

PMID:
29410330
32.

Host-pathogen systems for early drug discovery against tuberculosis.

Trofimov V, Costa-Gouveia J, Hoffmann E, Brodin P.

Curr Opin Microbiol. 2017 Oct;39:143-151. doi: 10.1016/j.mib.2017.11.017. Epub 2017 Nov 24. Review.

PMID:
29179041
33.

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton.

Song OR, Queval CJ, Iantomasi R, Delorme V, Marion S, Veyron-Churlet R, Werkmeister E, Popoff M, Ricard I, Jouny S, Deboosere N, Lafont F, Baulard A, Yeramian E, Marsollier L, Hoffmann E, Brodin P.

EMBO Rep. 2018 Jan;19(1):29-42. doi: 10.15252/embr.201744371. Epub 2017 Nov 15.

34.

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids.

Blanc L, Gilleron M, Prandi J, Song OR, Jang MS, Gicquel B, Drocourt D, Neyrolles O, Brodin P, Tiraby G, Vercellone A, Nigou J.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11205-11210. doi: 10.1073/pnas.1707840114. Epub 2017 Oct 2.

35.

Mass Cytometry Identifies Distinct Lung CD4+ T Cell Patterns in Löfgren's Syndrome and Non-Löfgren's Syndrome Sarcoidosis.

Kaiser Y, Lakshmikanth T, Chen Y, Mikes J, Eklund A, Brodin P, Achour A, Grunewald J.

Front Immunol. 2017 Sep 12;8:1130. doi: 10.3389/fimmu.2017.01130. eCollection 2017.

36.

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling.

Queval CJ, Song OR, Carralot JP, Saliou JM, Bongiovanni A, Deloison G, Deboosère N, Jouny S, Iantomasi R, Delorme V, Debrie AS, Park SJ, Gouveia JC, Tomavo S, Brosch R, Yoshimura A, Yeramian E, Brodin P.

Cell Rep. 2017 Sep 26;20(13):3188-3198. doi: 10.1016/j.celrep.2017.08.101.

37.

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis.

Nguyen PC, Delorme V, Bénarouche A, Martin BP, Paudel R, Gnawali GR, Madani A, Puppo R, Landry V, Kremer L, Brodin P, Spilling CD, Cavalier JF, Canaan S.

Sci Rep. 2017 Sep 18;7(1):11751. doi: 10.1038/s41598-017-11843-4.

38.

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages.

Escoll P, Song OR, Viana F, Steiner B, Lagache T, Olivo-Marin JC, Impens F, Brodin P, Hilbi H, Buchrieser C.

Cell Host Microbe. 2017 Sep 13;22(3):302-316.e7. doi: 10.1016/j.chom.2017.07.020. Epub 2017 Aug 31.

39.

Mass Cytometry and Topological Data Analysis Reveal Immune Parameters Associated with Complications after Allogeneic Stem Cell Transplantation.

Lakshmikanth T, Olin A, Chen Y, Mikes J, Fredlund E, Remberger M, Omazic B, Brodin P.

Cell Rep. 2017 Aug 29;20(9):2238-2250. doi: 10.1016/j.celrep.2017.08.021.

40.

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.

Song OR, Kim HB, Jouny S, Ricard I, Vandeputte A, Deboosere N, Marion E, Queval CJ, Lesport P, Bourinet E, Henrion D, Oh SB, Lebon G, Sandoz G, Yeramian E, Marsollier L, Brodin P.

Toxins (Basel). 2017 Jul 18;9(7). pii: E227. doi: 10.3390/toxins9070227.

41.

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.

Costa-Gouveia J, Pancani E, Jouny S, Machelart A, Delorme V, Salzano G, Iantomasi R, Piveteau C, Queval CJ, Song OR, Flipo M, Deprez B, Saint-André JP, Hureaux J, Majlessi L, Willand N, Baulard A, Brodin P, Gref R.

Sci Rep. 2017 Jul 14;7(1):5390. doi: 10.1038/s41598-017-05453-3. Erratum in: Sci Rep. 2018 May 10;8(1):7596.

42.

Continuous immunotypes describe human immune variation and predict diverse responses.

Kaczorowski KJ, Shekhar K, Nkulikiyimfura D, Dekker CL, Maecker H, Davis MM, Chakraborty AK, Brodin P.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6097-E6106. doi: 10.1073/pnas.1705065114. Epub 2017 Jul 10.

43.

Combining Flow and Mass Cytometry in the Search for Biomarkers in Chronic Graft-versus-Host Disease.

Stikvoort A, Chen Y, Rådestad E, Törlén J, Lakshmikanth T, Björklund A, Mikes J, Achour A, Gertow J, Sundberg B, Remberger M, Sundin M, Mattsson J, Brodin P, Uhlin M.

Front Immunol. 2017 Jun 19;8:717. doi: 10.3389/fimmu.2017.00717. eCollection 2017.

44.

The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education.

Ganesan S, Luu TT, Chambers BJ, Meinke S, Brodin P, Vivier E, Wetzel DM, Koleske AJ, Kadri N, Höglund P.

Scand J Immunol. 2017 Sep;86(3):135-142. doi: 10.1111/sji.12574.

45.

Expression of CD226 is associated to but not required for NK cell education.

Wagner AK, Kadri N, Snäll J, Brodin P, Gilfillan S, Colonna M, Bernhardt G, Höglund P, Kärre K, Chambers BJ.

Nat Commun. 2017 May 31;8:15627. doi: 10.1038/ncomms15627.

46.

Phenotypic assays for Mycobacterium tuberculosis infection.

Song OR, Deboosere N, Delorme V, Queval CJ, Deloison G, Werkmeister E, Lafont F, Baulard A, Iantomasi R, Brodin P.

Cytometry A. 2017 Oct;91(10):983-994. doi: 10.1002/cyto.a.23129. Epub 2017 May 19.

47.

Host-directed therapies offer novel opportunities for the fight against tuberculosis.

Machelart A, Song OR, Hoffmann E, Brodin P.

Drug Discov Today. 2017 Aug;22(8):1250-1257. doi: 10.1016/j.drudis.2017.05.005. Epub 2017 May 19. Review.

PMID:
28533187
48.

Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs.

Salzano G, Wankar J, Ottani S, Villemagne B, Baulard AR, Willand N, Brodin P, Manet I, Gref R.

Int J Pharm. 2017 Oct 15;531(2):577-587. doi: 10.1016/j.ijpharm.2017.05.030. Epub 2017 May 15.

PMID:
28522424
49.

Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis.

Camassa S, Palucci I, Iantomasi R, Cubeddu T, Minerva M, De Maio F, Jouny S, Petruccioli E, Goletti D, Ria F, Sali M, Sanguinetti M, Manganelli R, Rocca S, Brodin P, Delogu G.

Front Cell Infect Microbiol. 2017 Apr 21;7:137. doi: 10.3389/fcimb.2017.00137. eCollection 2017.

50.

Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections.

Valetti S, Xia X, Costa-Gouveia J, Brodin P, Bernet-Camard MF, Andersson M, Feiler A.

Nanomedicine (Lond). 2017 Apr;12(8):831-844. doi: 10.2217/nnm-2016-0364. Epub 2017 Mar 24.

PMID:
28338408

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