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Items: 1 to 50 of 85

1.

Toxicological assessment of the role of alcohol and drugs in drug-facilitated sexual assault cases in New Zealand.

Poulsen H, McCarthy MJ, Baker J, Verma A, Moir HJ, Brodie T, Thatti B, Trotter G, Rooney B.

J Anal Toxicol. 2020 Mar 11. pii: bkz110. doi: 10.1093/jat/bkz110. [Epub ahead of print]

PMID:
32159218
2.

Investigation on the Effect of Capillary Microsampling on Hematologic and Toxicokinetic Evaluation in Regulatory Safety Studies in Mice.

Wang B, Wang L, Batog A, Brodie T, Ramaiah L, Chadwick KD, Su T, Mangipudy R, Pilutla RC, Ji QC.

AAPS J. 2020 Mar 9;22(2):55. doi: 10.1208/s12248-020-00438-z.

PMID:
32152888
3.

Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma.

Nisa L, Francica P, Giger R, Medo M, Elicin O, Friese-Hamim M, Wilm C, Stroh C, Bojaxhiu B, Quintin A, Caversaccio MD, Dettmer MS, Buchwalder M, Brodie TM, Aebersold DM, Zimmer Y, Carey TE, Medová M.

Mol Cancer Ther. 2020 Feb;19(2):614-626. doi: 10.1158/1535-7163.MCT-18-1274. Epub 2019 Nov 19.

PMID:
31744898
4.

Adverse vacuolation in multiple tissues in cynomolgus monkeys following repeat-dose administration of a PEGylated protein.

Fletcher AM, Tellier P, Douville J, Mansell P, Graziano MJ, Mangipudy RS, Brodie TA, Achanzar WE.

Toxicol Lett. 2019 Dec 15;317:120-129. doi: 10.1016/j.toxlet.2019.09.023. Epub 2019 Sep 30.

PMID:
31580884
5.

Assessing the risk of drug crystallization in vivo.

Ruepp S, Janovitz E, Brodie T, White R, Santella J, Hynes J, Carman J, Pan D, Wu Y, Hanumegowda U, Gemzik B, Megill J, DiPiero J, Drexler D, Su CC, Hageman M.

J Pharmacol Toxicol Methods. 2019 Mar - Apr;96:1-8. doi: 10.1016/j.vascn.2018.12.003. Epub 2018 Dec 13.

PMID:
30553974
6.

Response to the Letter to the Editor Submitted by Dr. JoAnn C. L. Schuh.

Woicke J, Haile S, Mysore J, Peden M, Lejeune T, Sanderson TP, Brodie T.

Toxicol Pathol. 2018 Aug;46(6):721. doi: 10.1177/0192623318794180. No abstract available.

PMID:
30160207
7.

OMIP-045: Characterizing human head and neck tumors and cancer cell lines with mass cytometry.

Brodie TM, Tosevski V, Medová M.

Cytometry A. 2018 Apr;93(4):406-410. doi: 10.1002/cyto.a.23336. Epub 2018 Apr 12. No abstract available.

8.

Spontaneous Findings in the Eyes of Cynomolgus Monkeys ( Macaca fascicularis) of Mauritian Origin.

Woicke J, Haile S, Mysore J, Peden WM, Lejeune T, Sanderson T, Brodie T.

Toxicol Pathol. 2018 Apr;46(3):273-282. doi: 10.1177/0192623318758619. Epub 2018 Feb 25.

PMID:
29478386
9.

Broad Immune Monitoring and Profiling of T Cell Subsets with Mass Cytometry.

Brodie TM, Tosevski V.

Methods Mol Biol. 2018;1745:67-82. doi: 10.1007/978-1-4939-7680-5_4.

PMID:
29476463
10.

Safety assessment of propylparaben in juvenile rats.

Sivaraman L, Pouliot L, Wang B, Brodie T, Graziano M, McNerney ME.

Regul Toxicol Pharmacol. 2018 Feb;92:370-381. doi: 10.1016/j.yrtph.2017.12.009. Epub 2017 Dec 15.

PMID:
29248488
11.

Epicutaneous allergen application preferentially boosts specific T cell responses in sensitized patients.

Campana R, Moritz K, Neubauer A, Huber H, Henning R, Brodie TM, Kaider A, Sallusto F, Wöhrl S, Valenta R.

Sci Rep. 2017 Sep 14;7(1):11657. doi: 10.1038/s41598-017-10278-1.

12.

High-Dimensional Single-Cell Analysis with Mass Cytometry.

Brodie TM, Tosevski V.

Curr Protoc Immunol. 2017 Aug 1;118:5.11.1-5.11.25. doi: 10.1002/cpim.31.

PMID:
28762483
13.

Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses.

Tousa S, Semitekolou M, Morianos I, Banos A, Trochoutsou AI, Brodie TM, Poulos N, Samitas K, Kapasa M, Konstantopoulos D, Paraskevopoulos G, Gaga M, Hawrylowicz CM, Sallusto F, Xanthou G.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2891-E2900. doi: 10.1073/pnas.1616942114. Epub 2017 Mar 20.

14.

Drugged Drivers Blood Concentrations in England and Wales Prior to the Introduction of Per Se Limits.

Rooney B, Gouveia GJ, Isles N, Lawrence L, Brodie T, Grahovac Z, Chamberlain M, Trotter G.

J Anal Toxicol. 2017 Mar 1;41(2):140-145. doi: 10.1093/jat/bkw109.

PMID:
27798073
15.

OMIP-033: A comprehensive single step staining protocol for human T- and B-cell subsets.

Brodie T, Rothaeusler K, Sospedra M.

Cytometry A. 2016 Jul;89(7):629-32. doi: 10.1002/cyto.a.22889. Epub 2016 Jun 8. No abstract available.

16.

Frequent occurrence of T cell-mediated late reactions revealed by atopy patch testing with hypoallergenic rBet v 1 fragments.

Campana R, Moritz K, Marth K, Neubauer A, Huber H, Henning R, Blatt K, Hoermann G, Brodie TM, Kaider A, Valent P, Sallusto F, Wöhrl S, Valenta R.

J Allergy Clin Immunol. 2016 Feb;137(2):601-609.e8. doi: 10.1016/j.jaci.2015.08.042. Epub 2015 Oct 28.

17.

Two functionally distinct subsets of mast cells discriminated By IL-2-independent CD25 activities.

Deho' L, Leoni C, Brodie TM, Montagner S, De Simone M, Polletti S, Barozzi I, Natoli G, Monticelli S.

J Immunol. 2014 Sep 1;193(5):2196-206. doi: 10.4049/jimmunol.1400516. Epub 2014 Jul 25.

18.

The benefits of multidisciplinary safeguarding meetings.

Brodie T, Knight S.

Br J Gen Pract. 2014 Jul;64(624):e456-8. doi: 10.3399/bjgp14X680701. No abstract available.

19.

Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors.

Campion SL, Brodie TM, Fischer W, Korber BT, Rossetti A, Goonetilleke N, McMichael AJ, Sallusto F.

J Exp Med. 2014 Jun 30;211(7):1273-80. doi: 10.1084/jem.20130555. Epub 2014 Jun 23.

20.

The glucagon-like peptide-1-based therapeutics exenatide and saxagliptin did not cause detrimental effects on the pancreas in mice, rats, dogs and monkeys.

Roy D, Chadwick KD, Tatarkiewicz K, LaCerte C, Bergholm AM, Brodie T, Mangipudy RS, Parkes D, Graziano MJ, Reilly TP.

Diabetes Obes Metab. 2014 Oct;16(10):910-21. doi: 10.1111/dom.12294. Epub 2014 Apr 27.

PMID:
24666399
21.

The who's who of T-cell differentiation: human memory T-cell subsets.

Mahnke YD, Brodie TM, Sallusto F, Roederer M, Lugli E.

Eur J Immunol. 2013 Nov;43(11):2797-809. doi: 10.1002/eji.201343751. Epub 2013 Oct 30. Review.

22.

OMIP-018: chemokine receptor expression on human T helper cells.

Brodie T, Brenna E, Sallusto F.

Cytometry A. 2013 Jun;83(6):530-2. doi: 10.1002/cyto.a.22278. Epub 2013 Mar 15. No abstract available. Erratum in: Cytometry A. 2013 Nov;83(11):1041-5.

23.

Holoendemic malaria exposure is associated with altered Epstein-Barr virus-specific CD8(+) T-cell differentiation.

Chattopadhyay PK, Chelimo K, Embury PB, Mulama DH, Sumba PO, Gostick E, Ladell K, Brodie TM, Vulule J, Roederer M, Moormann AM, Price DA.

J Virol. 2013 Feb;87(3):1779-88. doi: 10.1128/JVI.02158-12. Epub 2012 Nov 21.

24.

T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts.

Oseroff C, Sidney J, Vita R, Tripple V, McKinney DM, Southwood S, Brodie TM, Sallusto F, Grey H, Alam R, Broide D, Greenbaum JA, Kolla R, Peters B, Sette A.

J Immunol. 2012 Aug 15;189(4):1800-11. doi: 10.4049/jimmunol.1200850. Epub 2012 Jul 11.

25.

Renal dysplasia in Beagle dogs: four cases.

Bruder MC, Shoieb AM, Shirai N, Boucher GG, Brodie TA.

Toxicol Pathol. 2010 Dec;38(7):1051-7. doi: 10.1177/0192623310382558. Epub 2010 Sep 30.

PMID:
20884818
26.

Immunologic and virologic events in early HIV infection predict subsequent rate of progression.

Ganesan A, Chattopadhyay PK, Brodie TM, Qin J, Gu W, Mascola JR, Michael NL, Follmann DA, Roederer M; Infectious Disease Clinical Research Program HIV Working Group.

J Infect Dis. 2010 Jan 15;201(2):272-84. doi: 10.1086/649430.

27.

A survey of patient views on receiving vascular outpatient letters.

Brodie T, Lewis DR.

Eur J Vasc Endovasc Surg. 2010 Jan;39(1):5-10. doi: 10.1016/j.ejvs.2009.09.019.

28.

PPAR alpha, more than PPAR delta, mediates the hepatic and skeletal muscle alterations induced by the PPAR agonist GW0742.

Faiola B, Falls JG, Peterson RA, Bordelon NR, Brodie TA, Cummings CA, Romach EH, Miller RT.

Toxicol Sci. 2008 Oct;105(2):384-94. doi: 10.1093/toxsci/kfn130. Epub 2008 Jun 30.

PMID:
18593727
29.

Correlation analysis of gene expression and clinical chemistry to identify biomarkers of skeletal myopathy in mice treated with PPAR agonist GW610742X.

Casey WM, Brodie T, Yoon L, Ni H, Jordan HL, Cariello NF.

Biomarkers. 2008 Jun;13(4):364-76. doi: 10.1080/13547500801903545 .

PMID:
18484352
30.

Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats.

Conway JG, Pink H, Bergquist ML, Han B, Depee S, Tadepalli S, Lin P, Crumrine RC, Binz J, Clark RL, Selph JL, Stimpson SA, Hutchins JT, Chamberlain SD, Brodie TA.

J Pharmacol Exp Ther. 2008 Jul;326(1):41-50. doi: 10.1124/jpet.107.129429. Epub 2008 Apr 23.

PMID:
18434589
31.

Immunomodulatory effects of the Lutzomyia longipalpis salivary gland protein maxadilan on mouse macrophages.

Brodie TM, Smith MC, Morris RV, Titus RG.

Infect Immun. 2007 May;75(5):2359-65. Epub 2007 Mar 5.

32.

Unilateral fixed dilated pupil in a well child.

Brodie T, Adalat S.

Arch Dis Child. 2006 Dec;91(12):961. No abstract available.

33.

Direct measurements of intervessel pit membrane hydraulic resistance in two angiosperm tree species.

Choat B, Brodie TW, Cobb AR, Zwieniecki MA, Holbrook NM.

Am J Bot. 2006 Jul;93(7):993-1000. doi: 10.3732/ajb.93.7.993.

34.

Educational supervision for the foundation programme.

Brodie T.

Br J Hosp Med (Lond). 2006 Mar;67(3):159. No abstract available.

PMID:
16562452
35.

Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling.

Böhm BB, Aigner T, Roy B, Brodie TA, Blobel CP, Burkhardt H.

Arthritis Rheum. 2005 Apr;52(4):1100-9.

36.

Potential role for ADAM15 in pathological neovascularization in mice.

Horiuchi K, Weskamp G, Lum L, Hammes HP, Cai H, Brodie TA, Ludwig T, Chiusaroli R, Baron R, Preissner KT, Manova K, Blobel CP.

Mol Cell Biol. 2003 Aug;23(16):5614-24.

37.

CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.

Tippin TK, Hamilton G, Moore L, Beaudet EJ, Jolley S, Brodie TA, Andrews RC, Becherer JD, McDougald DL, Gaul MD, Hoivik DJ, Mellon-Kusibab K, Lehmann J, Kliewer S, Novick S, Laethem R, Zhao Z, LeCluyse EL.

Drug Metab Dispos. 2003 Jul;31(7):870-7.

PMID:
12814963
38.

Role of hydrophobic interactions in the flavodoxin mediated electron transfer from photosystem I to ferredoxin-NADP+ reductase in Anabaena PCC 7119.

Nogués I, Martínez-Júlvez M, Navarro JA, Hervás M, Armenteros L, de la Rosa MA, Brodie TB, Hurley JK, Tollin G, Gómez-Moreno C, Medina M.

Biochemistry. 2003 Feb 25;42(7):2036-45.

PMID:
12590591
39.

Early alterations in the collagen meshwork and lesions in the ankles are associated with spontaneous osteoarthritis in guinea-pigs.

Han B, Cole AA, Shen Y, Brodie T, Williams JM.

Osteoarthritis Cartilage. 2002 Oct;10(10):778-84.

40.

Vascular effects of GI262570X (PPAR-gamma agonist) in the brown adipose tissue of Han Wistar rats: a review of 1-month, 13-week, 27-week and 2-year oral toxicity studies.

Elangbam CS, Brodie TA, Brown HR, Nold JB, Raczniak TJ, Tyler RD, Lightfoot RM, Wall HG.

Toxicol Pathol. 2002 Jul-Aug;30(4):420-6.

PMID:
12187934
41.

Structure-function relationships in Anabaena ferredoxin/ferredoxin:NADP(+) reductase electron transfer: insights from site-directed mutagenesis, transient absorption spectroscopy and X-ray crystallography.

Hurley JK, Morales R, Martínez-Júlvez M, Brodie TB, Medina M, Gómez-Moreno C, Tollin G.

Biochim Biophys Acta. 2002 Apr 22;1554(1-2):5-21. Review.

42.

Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life.

Weskamp G, Cai H, Brodie TA, Higashyama S, Manova K, Ludwig T, Blobel CP.

Mol Cell Biol. 2002 Mar;22(5):1537-44.

43.

Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases.

Conway JG, Andrews RC, Beaudet B, Bickett DM, Boncek V, Brodie TA, Clark RL, Crumrine RC, Leenitzer MA, McDougald DL, Han B, Hedeen K, Lin P, Milla M, Moss M, Pink H, Rabinowitz MH, Tippin T, Scates PW, Selph J, Stimpson SA, Warner J, Becherer JD.

J Pharmacol Exp Ther. 2001 Sep;298(3):900-8.

PMID:
11504783
44.

Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channel.

Li X, Bradford BU, Wheeler MD, Stimpson SA, Pink HM, Brodie TA, Schwab JH, Thurman RG.

Infect Immun. 2001 Sep;69(9):5883-91.

45.

Role of a cluster of hydrophobic residues near the FAD cofactor in Anabaena PCC 7119 ferredoxin-NADP+ reductase for optimal complex formation and electron transfer to ferredoxin.

Martínez-Júlvez M, Nogués I, Faro M, Hurley JK, Brodie TB, Mayoral T, Sanz-Aparicio J, Hermoso JA, Stankovich MT, Medina M, Tollin G, Gómez-Moreno C.

J Biol Chem. 2001 Jul 20;276(29):27498-510. Epub 2001 May 7.

46.

Highly nonproductive complexes with Anabaena ferredoxin at low ionic strength are induced by nonconservative amino acid substitutions at Glu139 in Anabaena ferredoxin:NADP+ reductase.

Hurley JK, Faro M, Brodie TB, Hazzard JT, Medina M, Gómez-Moreno C, Tollin G.

Biochemistry. 2000 Nov 14;39(45):13695-702.

PMID:
11076508
47.

Highly cooperative homodimerization is a conserved property of neural POU proteins.

Rhee JM, Gruber CA, Brodie TB, Trieu M, Turner EE.

J Biol Chem. 1998 Dec 18;273(51):34196-205.

48.

Lys75 of Anabaena ferredoxin-NADP+ reductase is a critical residue for binding ferredoxin and flavodoxin during electron transfer.

Martínez-Júlvez M, Medina M, Hurley JK, Hafezi R, Brodie TB, Tollin G, Gómez-Moreno C.

Biochemistry. 1998 Sep 29;37(39):13604-13.

PMID:
9753447
49.

The relationship of menstrual irregularity to type 2 diabetes in Pima Indian women.

Roumain J, Charles MA, de Courten MP, Hanson RL, Brodie TD, Pettitt DJ, Knowler WC.

Diabetes Care. 1998 Mar;21(3):346-9.

PMID:
9540014
50.

Systemic allergy to endogenous insulin during therapy with recombinant DNA (rDNA) insulin.

Alvarez-Thull L, Rosenwasser LJ, Brodie TD.

Ann Allergy Asthma Immunol. 1996 Mar;76(3):253-6.

PMID:
8634879

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