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Items: 1 to 50 of 416

1.

Pharmacological outcomes in teenagers with newly diagnosed epilepsy: A 30-year cohort study.

Alsfouk BA, Alsfouk AA, Chen Z, Kwan P, Brodie MJ.

Epilepsia. 2019 Jun;60(6):1083-1090. doi: 10.1111/epi.15664. Epub 2019 May 21.

PMID:
31111485
2.

Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy.

Walker LE, Frigerio F, Ravizza T, Ricci E, Tse K, Jenkins RE, Sills GJ, Jorgensen A, Porcu L, Thippeswamy T, Alapirtti T, Peltola J, Brodie MJ, Park BK, Marson AG, Antoine DJ, Vezzani A, Pirmohamed M.

J Clin Invest. 2019 Apr 8;130:2166. doi: 10.1172/JCI129285. eCollection 2019 Apr 8. No abstract available.

3.

Management of epilepsy in women.

Stephen LJ, Harden C, Tomson T, Brodie MJ.

Lancet Neurol. 2019 May;18(5):481-491. doi: 10.1016/S1474-4422(18)30495-2. Epub 2019 Mar 8. Review.

PMID:
30857949
4.

Perampanel in routine clinical use across Europe: Pooled, multicenter, observational data.

Rohracher A, Zimmermann G, Villanueva V, Garamendi I, Sander JW, Wehner T, Shankar R, Ben-Menachem E, Brodie MJ, Pensel MC, Di Gennaro G, Maurousset A, Strzelczyk A, Rheims S, Rácz A, Menzler K, Bertol-Alegre V, García-Morales I, López-González FJ, Toledo M, Carpenter KJ, Trinka E.

Epilepsia. 2018 Sep;59(9):1727-1739. doi: 10.1111/epi.14520. Epub 2018 Jul 25. Erratum in: Epilepsia. 2018 Nov;59(11):2167.

PMID:
30047129
5.

Brivaracetam-induced elevation of carbamazepine epoxide levels: A post-hoc analysis from the clinical development program.

Brodie MJ, Fakhoury T, McDonough B, Colson AO, Stockis A, Elmoufti S, Whitesides J.

Epilepsy Res. 2018 Sep;145:55-62. doi: 10.1016/j.eplepsyres.2018.06.002. Epub 2018 Jun 4.

PMID:
29908435
6.

The 2017 ILAE classification of seizure types and the epilepsies: what do people with epilepsy and their caregivers need to know?

Brodie MJ, Zuberi SM, Scheffer IE, Fisher RS.

Epileptic Disord. 2018 Apr 1;20(2):77-87. doi: 10.1684/epd.2018.0957.

7.

Lay epilepsy organizations: The key for research funding?

Mifsud J, Brodie MJ.

Epilepsy Behav. 2018 Apr;81:123-124. doi: 10.1016/j.yebeh.2017.12.027. Epub 2018 Feb 18. No abstract available.

PMID:
29463469
8.

Brivaracetam: a novel antiepileptic drug for focal-onset seizures.

Stephen LJ, Brodie MJ.

Ther Adv Neurol Disord. 2017 Nov 23;11:1756285617742081. doi: 10.1177/1756285617742081. eCollection 2018. Review.

9.

Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.

McCormack M, Gui H, Ingason A, Speed D, Wright GEB, Zhang EJ, Secolin R, Yasuda C, Kwok M, Wolking S, Becker F, Rau S, Avbersek A, Heggeli K, Leu C, Depondt C, Sills GJ, Marson AG, Auce P, Brodie MJ, Francis B, Johnson MR, Koeleman BPC, Striano P, Coppola A, Zara F, Kunz WS, Sander JW, Lerche H, Klein KM, Weckhuysen S, Krenn M, Gudmundsson LJ, Stefánsson K, Krause R, Shear N, Ross CJD, Delanty N; EPIGEN Consortium;, Pirmohamed M, Carleton BC; Canadian Pharmacogenomics Network for Drug Safety;, Cendes F, Lopes-Cendes I, Liao WP, O'Brien TJ, Sisodiya SM; EpiPGX Consortium;, Cherny S, Kwan P, Baum L; International League Against Epilepsy Consortium on Complex Epilepsies;, Cavalleri GL.

Neurology. 2018 Jan 23;90(4):e332-e341. doi: 10.1212/WNL.0000000000004853. Epub 2017 Dec 29. Erratum in: Neurology. 2018 Oct 16;91(16):765.

10.

Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs: A 30-Year Longitudinal Cohort Study.

Chen Z, Brodie MJ, Liew D, Kwan P.

JAMA Neurol. 2018 Mar 1;75(3):279-286. doi: 10.1001/jamaneurol.2017.3949.

11.

Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

Klein P, Dingledine R, Aronica E, Bernard C, Blümcke I, Boison D, Brodie MJ, Brooks-Kayal AR, Engel J Jr, Forcelli PA, Hirsch LJ, Kaminski RM, Klitgaard H, Kobow K, Lowenstein DH, Pearl PL, Pitkänen A, Puhakka N, Rogawski MA, Schmidt D, Sillanpää M, Sloviter RS, Steinhäuser C, Vezzani A, Walker MC, Löscher W.

Epilepsia. 2018 Jan;59(1):37-66. doi: 10.1111/epi.13965. Epub 2017 Dec 15. Review.

12.

Cannabinoids for epilepsy: What do we know and where do we go?

Brodie MJ, Ben-Menachem E.

Epilepsia. 2018 Feb;59(2):291-296. doi: 10.1111/epi.13973. Epub 2017 Dec 6. Review.

13.

Introduction to the International Bureau for Epilepsy (IBE) platform and its newly elected president Martin Brodie.

Brodie MJ.

Epilepsy Behav. 2017 Oct;75:256-257. doi: 10.1016/j.yebeh.2017.06.032. Epub 2017 Sep 5. No abstract available.

PMID:
28887128
14.

Psychiatric side effects and antiepileptic drugs: Observations from prospective audits.

Stephen LJ, Wishart A, Brodie MJ.

Epilepsy Behav. 2017 Jun;71(Pt A):73-78. doi: 10.1016/j.yebeh.2017.04.003. Epub 2017 May 25.

PMID:
28551500
15.

Sodium Channel Blockers in the Treatment of Epilepsy.

Brodie MJ.

CNS Drugs. 2017 Jul;31(7):527-534. doi: 10.1007/s40263-017-0441-0. Review.

PMID:
28523600
16.

Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy.

Walker LE, Frigerio F, Ravizza T, Ricci E, Tse K, Jenkins RE, Sills GJ, Jorgensen A, Porcu L, Thippeswamy T, Alapirtti T, Peltola J, Brodie MJ, Park BK, Marson AG, Antoine DJ, Vezzani A, Pirmohamed M.

J Clin Invest. 2017 Jun 1;127(6):2118-2132. doi: 10.1172/JCI92001. Epub 2017 May 15. Retraction in: J Clin Invest. 2019 Apr 8;130:2166.

17.

Tolerability and Safety of Commonly Used Antiepileptic Drugs in Adolescents and Adults: A Clinician's Overview.

Brodie MJ.

CNS Drugs. 2017 Feb;31(2):135-147. doi: 10.1007/s40263-016-0406-8. Review.

PMID:
28101765
18.

Pharmacokinetic interaction of brivaracetam on carbamazepine in adult patients with epilepsy, with and without valproate co-administration.

Stockis A, Sargentini-Maier ML, Brodie MJ.

Epilepsy Res. 2016 Dec;128:163-168. doi: 10.1016/j.eplepsyres.2016.11.001. Epub 2016 Nov 9.

PMID:
27842261
19.

Tolerability, safety, and efficacy of adjunctive brivaracetam for focal seizures in older patients: A pooled analysis from three phase III studies.

Brodie MJ, Whitesides J, Schiemann J, D'Souza J, Johnson ME.

Epilepsy Res. 2016 Nov;127:114-118. doi: 10.1016/j.eplepsyres.2016.08.018. Epub 2016 Aug 18.

20.

Outcomes in newly diagnosed epilepsy in adolescents and adults: Insights across a generation in Scotland.

Brodie MJ.

Seizure. 2017 Jan;44:206-210. doi: 10.1016/j.seizure.2016.08.010. Epub 2016 Sep 3. Review.

21.

Pharmacological Treatment of Drug-Resistant Epilepsy in Adults: a Practical Guide.

Brodie MJ.

Curr Neurol Neurosci Rep. 2016 Sep;16(9):82. doi: 10.1007/s11910-016-0678-x. Review.

PMID:
27443649
22.

Epilepsy, Antiepileptic Drugs, and Aggression: An Evidence-Based Review.

Brodie MJ, Besag F, Ettinger AB, Mula M, Gobbi G, Comai S, Aldenkamp AP, Steinhoff BJ.

Pharmacol Rev. 2016 Jul;68(3):563-602. doi: 10.1124/pr.115.012021. Review.

23.

Clobazam and clonazepam use in epilepsy: Results from a UK database incident user cohort study.

Brodie MJ, Chung S, Wade A, Quelen C, Guiraud-Diawara A, François C, Verpillat P, Shen V, Isojarvi J.

Epilepsy Res. 2016 Jul;123:68-74. doi: 10.1016/j.eplepsyres.2016.04.003. Epub 2016 Apr 11.

24.

Modern management of juvenile myoclonic epilepsy.

Brodie MJ.

Expert Rev Neurother. 2016 Jun;16(6):681-8. doi: 10.1080/14737175.2016.1179113. Epub 2016 May 3. Review.

PMID:
27082040
25.

Prospective audit with adjunctive perampanel: Preliminary observations in focal epilepsy.

Brodie MJ, Stephen LJ.

Epilepsy Behav. 2016 Jan;54:100-3. doi: 10.1016/j.yebeh.2015.11.002. Epub 2015 Dec 14.

PMID:
26700063
26.

Pharmacological outcomes in juvenile myoclonic epilepsy: Support for sodium valproate.

Chowdhury A, Brodie MJ.

Epilepsy Res. 2016 Jan;119:62-6. doi: 10.1016/j.eplepsyres.2015.11.012. Epub 2015 Dec 1.

PMID:
26675554
27.

Practical Use of Newer Antiepileptic Drugs as Adjunctive Therapy in Focal Epilepsy.

Brodie MJ.

CNS Drugs. 2015 Nov;29(11):893-904. doi: 10.1007/s40263-015-0285-4. Review.

PMID:
26507832
28.

Perampanel for focal epilepsy: insights from early clinical experience.

Trinka E, Steinhoff BJ, Nikanorova M, Brodie MJ.

Acta Neurol Scand. 2016 Mar;133(3):160-72. doi: 10.1111/ane.12529. Epub 2015 Oct 28. Review.

29.

A case report: retigabine induced oral mucosal dyspigmentation of the hard palate.

Beacher NG, Brodie MJ, Goodall C.

BMC Oral Health. 2015 Oct 9;15(1):122. doi: 10.1186/s12903-015-0102-y.

30.

Analysis of pooled phase III trials of adjunctive perampanel for epilepsy: Impact of mechanism of action and pharmacokinetics on clinical outcomes.

Kwan P, Brodie MJ, Laurenza A, FitzGibbon H, Gidal BE.

Epilepsy Res. 2015 Nov;117:117-24. doi: 10.1016/j.eplepsyres.2015.09.002. Epub 2015 Sep 9.

31.

Third International Congress on Epilepsy, Brain, and Mind: Part 2.

Rektor I, Schachter SC, Arya R, Arzy S, Braakman H, Brodie MJ, Brugger P, Chang BS, Guekht A, Hermann B, Hesdorffer DC, Jones-Gotman M, Kanner AM, Garcia-Larrea L, Mareš P, Mula M, Neufeld M, Risse GL, Ryvlin P, Seeck M, Tomson T, Korczyn AD.

Epilepsy Behav. 2015 Sep;50:138-59. doi: 10.1016/j.yebeh.2015.07.014. Epub 2015 Aug 8. Review.

32.

Validation of a multigenic model to predict seizure control in newly treated epilepsy.

Shazadi K, Petrovski S, Roten A, Miller H, Huggins RM, Brodie MJ, Pirmohamed M, Johnson MR, Marson AG, O'Brien TJ, Sills GJ.

Epilepsy Res. 2014 Dec;108(10):1797-805. doi: 10.1016/j.eplepsyres.2014.08.022. Epub 2014 Sep 16.

PMID:
25282706
33.

Happy anniversary, epilepsy & behavior.

Brodie MJ.

Epilepsy Behav. 2014 Nov;40:79. doi: 10.1016/j.yebeh.2014.09.001. Epub 2014 Oct 3. No abstract available.

PMID:
25281295
34.

Adjunctive lacosamide--5 years' clinical experience.

Stephen LJ, Kelly K, Parker P, Brodie MJ.

Epilepsy Res. 2014 Oct;108(8):1385-91. doi: 10.1016/j.eplepsyres.2014.06.018. Epub 2014 Jul 6.

PMID:
25064538
35.

Adjunctive use of ezogabine/retigabine with either traditional sodium channel blocking antiepileptic drugs (AEDs) or AEDs with other mechanisms of action: Evaluation of efficacy and tolerability.

Brodie MJ, French JA, McDonald SA, Lee WJ, Adams B, Scott A, Nohria V, DeRossett S.

Epilepsy Res. 2014 Jul;108(5):989-94. doi: 10.1016/j.eplepsyres.2014.03.008. Epub 2014 Mar 26.

PMID:
24726452
36.

Prospective audits with newer antiepileptic drugs in focal epilepsy: insights into population responses?

Brodie MJ, Kelly K, Stephen LJ.

Epilepsy Behav. 2014 Feb;31:73-6. doi: 10.1016/j.yebeh.2013.11.016. Epub 2013 Dec 20.

PMID:
24361766
37.

Safety and tolerability of different titration rates of retigabine (ezogabine) in patients with partial-onset seizures.

Biton V, Gil-Nagel A, Brodie MJ, Derossett SE, Nohria V.

Epilepsy Res. 2013 Nov;107(1-2):138-45. doi: 10.1016/j.eplepsyres.2013.08.021. Epub 2013 Sep 4.

PMID:
24094693
38.

Uncontrolled epilepsy is not necessarily the same as drug-resistant epilepsy: differences between populations with newly diagnosed epilepsy and chronic epilepsy.

Hao X, Goldberg D, Kelly K, Stephen L, Kwan P, Brodie MJ.

Epilepsy Behav. 2013 Oct;29(1):4-6. doi: 10.1016/j.yebeh.2013.06.019. Epub 2013 Aug 1.

PMID:
23911352
39.

Epilepsy, cognition, and neuropsychiatry (Epilepsy, Brain, and Mind, part 2).

Korczyn AD, Schachter SC, Brodie MJ, Dalal SS, Engel J Jr, Guekht A, Hecimovic H, Jerbi K, Kanner AM, Johannessen Landmark C, Mares P, Marusic P, Meletti S, Mula M, Patsalos PN, Reuber M, Ryvlin P, Štillová K, Tuchman R, Rektor I.

Epilepsy Behav. 2013 Aug;28(2):283-302. doi: 10.1016/j.yebeh.2013.03.012. Epub 2013 Jun 10. Review.

40.

Meta-analyses of antiepileptic drugs for refractory partial (focal) epilepsy: an observation.

Brodie MJ.

Br J Clin Pharmacol. 2013 Nov;76(5):630-1. doi: 10.1111/bcp.12176. No abstract available.

41.

Road to refractory epilepsy: the Glasgow story.

Brodie MJ.

Epilepsia. 2013 May;54 Suppl 2:5-8. doi: 10.1111/epi.12175. Review.

42.

Early predictors of outcome in newly diagnosed epilepsy.

Mohanraj R, Brodie MJ.

Seizure. 2013 Jun;22(5):333-44. doi: 10.1016/j.seizure.2013.02.002. Epub 2013 Apr 11. Review.

43.

Prevalence of neurologic autoantibodies in cohorts of patients with new and established epilepsy.

Brenner T, Sills GJ, Hart Y, Howell S, Waters P, Brodie MJ, Vincent A, Lang B.

Epilepsia. 2013 Jun;54(6):1028-35. doi: 10.1111/epi.12127. Epub 2013 Mar 6.

44.

Current position of phenobarbital in epilepsy and its future.

Brodie MJ, Kwan P.

Epilepsia. 2012 Dec;53 Suppl 8:40-6. doi: 10.1111/epi.12027. Review.

45.

Zonisamide: its pharmacology, efficacy and safety in clinical trials.

Brodie MJ, Ben-Menachem E, Chouette I, Giorgi L.

Acta Neurol Scand Suppl. 2012;(194):19-28. doi: 10.1111/ane.12016. Review.

PMID:
23106522
46.

Effect of dosage failed of first antiepileptic drug on subsequent outcome.

Brodie MJ, Barry SJ, Bamagous GA, Kwan P.

Epilepsia. 2013 Jan;54(1):194-8. doi: 10.1111/j.1528-1167.2012.03722.x. Epub 2012 Oct 25.

47.

Enzyme induction with antiepileptic drugs: cause for concern?

Brodie MJ, Mintzer S, Pack AM, Gidal BE, Vecht CJ, Schmidt D.

Epilepsia. 2013 Jan;54(1):11-27. doi: 10.1111/j.1528-1167.2012.03671.x. Epub 2012 Sep 27. Review.

48.

Novel trial designs for monotherapy.

Brodie MJ.

Epileptic Disord. 2012 Jun;14(2):132-7. Review.

49.

Pharmacoresistance.

Potschka H, Brodie MJ.

Handb Clin Neurol. 2012;108:741-57. doi: 10.1016/B978-0-444-52899-5.00025-3. Review. No abstract available.

PMID:
22939063
50.

Safety and efficacy of ezogabine (retigabine) in adults with refractory partial-onset seizures: Interim results from two ongoing open-label studies.

Gil-Nagel A, Brodie MJ, Leroy R, Cyr T, Hall S, Castiglia M, Twomey C, VanLandingham K.

Epilepsy Res. 2012 Nov;102(1-2):117-21. doi: 10.1016/j.eplepsyres.2012.05.007. Epub 2012 Jul 5.

PMID:
22771137

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