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Items: 1 to 50 of 115

1.

Genome-wide analysis of genes encoding core components of the ubiquitin system in soybean (Glycine max) reveals a potential role for ubiquitination in host immunity against soybean cyst nematode.

Zhang C, Song L, Choudhary MK, Zhou B, Sun G, Broderick K, Giesler L, Zeng L.

BMC Plant Biol. 2018 Jul 18;18(1):149. doi: 10.1186/s12870-018-1365-7.

2.

Delineating the cell death mechanisms associated with skin electroporation.

Schultheis K, Smith TRF, Kiosses WB, Kraynyak KA, Wong A, Oh J, Broderick KE.

Hum Gene Ther Methods. 2018 Jun 28. doi: 10.1089/hgtb.2017.105. [Epub ahead of print]

PMID:
29953259
3.

Tumor Site and Breast Cancer Prognosis.

Siotos C, McColl M, Psoter K, Gilmore RC, Sebai ME, Broderick KP, Jacobs LK, Irwin S, Rosson GD, Habibi M.

Clin Breast Cancer. 2018 May 29. pii: S1526-8209(18)30299-4. doi: 10.1016/j.clbc.2018.05.007. [Epub ahead of print]

PMID:
29941391
4.

Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques.

Hu X, Lu Z, Valentin A, Rosati M, Broderick KE, Sardesai NY, Marx PA, Mullins JI, Pavlakis GN, Felber BK.

Hum Vaccin Immunother. 2018 Jun 25:1-15. doi: 10.1080/21645515.2018.1489949. [Epub ahead of print]

PMID:
29939820
5.

DNA Vaccine-Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination.

Hu X, Valentin A, Cai Y, Dayton F, Rosati M, Ramírez-Salazar EG, Kulkarni V, Broderick KE, Sardesai NY, Wyatt LS, Earl PL, Moss B, Mullins JI, Pavlakis GN, Felber BK.

Hum Gene Ther. 2018 Jun 21. doi: 10.1089/hum.2018.065. [Epub ahead of print]

PMID:
29869530
6.

Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques.

Singh S, Ramírez-Salazar EG, Doueiri R, Valentin A, Rosati M, Hu X, Keele BF, Shen X, Tomaras GD, Ferrari G, LaBranche C, Montefiori DC, Das J, Alter G, Trinh HV, Hamlin C, Rao M, Dayton F, Bear J, Chowdhury B, Alicea C, Lifson JD, Broderick KE, Sardesai NY, Sivananthan SJ, Fox CB, Reed SG, Venzon DJ, Hirsch VM, Pavlakis GN, Felber BK.

J Virol. 2018 Jul 17;92(15). pii: e00281-18. doi: 10.1128/JVI.00281-18. Print 2018 Aug 1.

7.

Collagen deposition in chronic hidradenitis suppurativa: potential role for CD163+ macrophages.

Byrd AS, Kerns ML, Williams DW, Zarif JC, Rosenberg AZ, Delsante M, Liu H, Dillen CA, Maynard JP, Caffrey JA, Sacks JM, Milner SM, Aliu O, Broderick KP, Lew LS, Miller LS, Kang S, Okoye GA.

Br J Dermatol. 2018 Mar 30. doi: 10.1111/bjd.16600. [Epub ahead of print] No abstract available.

PMID:
29603182
8.

Non-organic Vision Loss in the Afghanistan and Iraq Conflicts.

Broderick KM, Ableman TB, Weber ED, Enzenauer RW, Wain HJ, Wroblewski KJ.

Neuroophthalmology. 2017 Mar 30;41(4):175-181. doi: 10.1080/01658107.2017.1295998. eCollection 2017 Aug.

9.

An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer.

Miyamoto DT, Lee RJ, Kalinich M, LiCausi JA, Zheng Y, Chen T, Milner JD, Emmons E, Ho U, Broderick K, Silva E, Javaid S, Kwan TT, Hong X, Dahl DM, McGovern FJ, Efstathiou JA, Smith MR, Sequist LV, Kapur R, Wu CL, Stott SL, Ting DT, Giobbie-Hurder A, Toner M, Maheswaran S, Haber DA.

Cancer Discov. 2018 Mar;8(3):288-303. doi: 10.1158/2159-8290.CD-16-1406. Epub 2018 Jan 4.

PMID:
29301747
10.

DMAb inoculation of synthetic cross reactive antibodies protects against lethal influenza A and B infections.

Elliott STC, Kallewaard NL, Benjamin E, Wachter-Rosati L, McAuliffe JM, Patel A, Smith TRF, Schultheis K, Park DH, Flingai S, Wise MC, Mendoza J, Ramos S, Broderick KE, Yan J, Humeau LM, Sardesai NY, Muthumani K, Zhu Q, Weiner DB.

NPJ Vaccines. 2017 Jul 6;2:18. doi: 10.1038/s41541-017-0020-x. eCollection 2017.

11.

In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine.

Muthumani K, Griffin BD, Agarwal S, Kudchodkar SB, Reuschel EL, Choi H, Kraynyak KA, Duperret EK, Keaton AA, Chung C, Kim YK, Booth SA, Racine T, Yan J, Morrow MP, Jiang J, Lee B, Ramos S, Broderick KE, Reed CC, Khan AS, Humeau L, Ugen KE, Park YK, Maslow JN, Sardesai NY, Joseph Kim J, Kobinger GP, Weiner DB.

NPJ Vaccines. 2016 Nov 10;1:16021. doi: 10.1038/npjvaccines.2016.21. eCollection 2016.

12.

Emergency department naloxone rescue kit dispensing and patient follow-up.

Kaucher KA, Acquisto NM, Broderick KB.

Am J Emerg Med. 2018 Aug;36(8):1503-1504. doi: 10.1016/j.ajem.2017.12.020. Epub 2017 Dec 7. No abstract available.

PMID:
29237542
13.

DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs.

Cashman KA, Wilkinson ER, Wollen SE, Shamblin JD, Zelko JM, Bearss JJ, Zeng X, Broderick KE, Schmaljohn CS.

Hum Vaccin Immunother. 2017 Dec 2;13(12):3010-3019. doi: 10.1080/21645515.2017.1382780. Epub 2017 Nov 14.

14.

Oncoplastic Breast Reconstruction: Should All Patients be Considered?

Habibi M, Broderick KP, Sebai ME, Jacobs LK.

Surg Oncol Clin N Am. 2018 Jan;27(1):167-180. doi: 10.1016/j.soc.2017.07.007. Review.

PMID:
29132559
15.

Adipose tissue: a new target for electroporation-enhanced DNA vaccines.

Fisher PD, Brambila CJ, McCoy JR, Kiosses WB, Mendoza JM, Oh J, Yung BS, Schultheis K, Smith TRF, Broderick KE.

Gene Ther. 2017 Dec;24(12):757-767. doi: 10.1038/gt.2017.96. Epub 2017 Nov 6.

16.

Broad cross-protective anti-hemagglutination responses elicited by influenza microconsensus DNA vaccine.

Yan J, Morrow MP, Chu JS, Racine T, Reed CC, Khan AS, Broderick KE, Kim JJ, Kobinger GP, Sardesai NY, Weiner DB.

Vaccine. 2018 May 24;36(22):3079-3089. doi: 10.1016/j.vaccine.2017.09.086.

PMID:
29100705
17.

A DNA vaccine delivered by dermal electroporation fully protects cynomolgus macaques against Lassa fever.

Cashman KA, Wilkinson ER, Shaia CI, Facemire PR, Bell TM, Bearss JJ, Shamblin JD, Wollen SE, Broderick KE, Sardesai NY, Schmaljohn CS.

Hum Vaccin Immunother. 2017 Dec 2;13(12):2902-2911. doi: 10.1080/21645515.2017.1356500. Epub 2017 Oct 18.

18.

Fidaxomicin versus Vancomycin as a First-Line Treatment for Clostridium difficile-Associated Diarrhea in Specific Patient Populations: A Pharmacoeconomic Evaluation.

Reveles KR, Backo JL, Corvino FA, Zivkovic M, Broderick KC.

Pharmacotherapy. 2017 Dec;37(12):1489-1497. doi: 10.1002/phar.2049. Epub 2017 Nov 27.

PMID:
29044643
19.

An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model.

Patel A, DiGiandomenico A, Keller AE, Smith TRF, Park DH, Ramos S, Schultheis K, Elliott STC, Mendoza J, Broderick KE, Wise MC, Yan J, Jiang J, Flingai S, Khan AS, Muthumani K, Humeau L, Cheng LI, Wachter-Rosati L, Stover CK, Sardesai NY, Weiner DB.

Nat Commun. 2017 Sep 21;8(1):637. doi: 10.1038/s41467-017-00576-7.

20.

Nucleic acid-based vaccines targeting respiratory syncytial virus: Delivering the goods.

Smith TRF, Schultheis K, Broderick KE.

Hum Vaccin Immunother. 2017 Nov 2;13(11):2626-2629. doi: 10.1080/21645515.2017.1363134.

21.

Early Immunomodulatory Effects of Implanted Human Perivascular Stromal Cells During Bone Formation.

Meyers CA, Xu J, Zhang L, Asatrian G, Ding C, Yan N, Broderick K, Sacks J, Goyal R, Zhang X, Ting K, Péault B, Soo C, James AW.

Tissue Eng Part A. 2018 Mar;24(5-6):448-457. doi: 10.1089/ten.TEA.2017.0023. Epub 2017 Aug 15.

PMID:
28683667
22.

HIV Env conserved element DNA vaccine alters immunodominance in macaques.

Hu X, Valentin A, Rosati M, Manocheewa S, Alicea C, Chowdhury B, Bear J, Broderick KE, Sardesai NY, Gall SL, Mullins JI, Pavlakis GN, Felber BK.

Hum Vaccin Immunother. 2017 Dec 2;13(12):2859-2871. doi: 10.1080/21645515.2017.1339852. Epub 2017 Jul 5.

23.

Herpes zoster ophthalmicus and strabismus: a unique cause of secondary Brown syndrome.

Broderick KM, Raymond WR 4th, Boden JH.

J AAPOS. 2017 Aug;21(4):335-337. doi: 10.1016/j.jaapos.2017.06.003. Epub 2017 Jun 15.

PMID:
28625469
24.

Development of an intradermal DNA vaccine delivery strategy to achieve single-dose immunity against respiratory syncytial virus.

Smith TRF, Schultheis K, Morrow MP, Kraynyak KA, McCoy JR, Yim KC, Muthumani K, Humeau L, Weiner DB, Sardesai NY, Broderick KE.

Vaccine. 2017 May 15;35(21):2840-2847. doi: 10.1016/j.vaccine.2017.04.008. Epub 2017 Apr 14.

25.

Augmentation of cellular and humoral immune responses to HPV16 and HPV18 E6 and E7 antigens by VGX-3100.

Morrow MP, Kraynyak KA, Sylvester AJ, Shen X, Amante D, Sakata L, Parker L, Yan J, Boyer J, Roh C, Humeau L, Khan AS, Broderick K, Marcozzi-Pierce K, Giffear M, Lee J, Trimble CL, Kim JJ, Sardesai NY, Weiner DB, Bagarazzi ML.

Mol Ther Oncolytics. 2016 Nov 30;3:16025. doi: 10.1038/mto.2016.25. eCollection 2016.

26.

Enhanced Delivery of DNA or RNA Vaccines by Electroporation.

Broderick KE, Humeau LM.

Methods Mol Biol. 2017;1499:193-200.

PMID:
27987151
27.

Characterization of guinea pig T cell responses elicited after EP-assisted delivery of DNA vaccines to the skin.

Schultheis K, Schaefer H, Yung BS, Oh J, Muthumani K, Humeau L, Broderick KE, Smith TR.

Vaccine. 2017 Jan 3;35(1):61-70. doi: 10.1016/j.vaccine.2016.11.052. Epub 2016 Nov 25.

28.

Mortality, Hospital Costs, Payments, and Readmissions Associated With Clostridium difficile Infection Among Medicare Beneficiaries.

Drozd EM, Inocencio TJ, Braithwaite S, Jagun D, Shah H, Quon NC, Broderick KC, Kuti JL.

Infect Dis Clin Pract (Baltim Md). 2015 Nov;23(6):318-323. Epub 2015 Nov 2.

29.

DNA Prime-Boost Vaccine Regimen To Increase Breadth, Magnitude, and Cytotoxicity of the Cellular Immune Responses to Subdominant Gag Epitopes of Simian Immunodeficiency Virus and HIV.

Hu X, Valentin A, Dayton F, Kulkarni V, Alicea C, Rosati M, Chowdhury B, Gautam R, Broderick KE, Sardesai NY, Martin MA, Mullins JI, Pavlakis GN, Felber BK.

J Immunol. 2016 Nov 15;197(10):3999-4013. Epub 2016 Oct 12.

30.

Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii.

El Bissati K, Chentoufi AA, Krishack PA, Zhou Y, Woods S, Dubey JP, Vang L, Lykins J, Broderick KE, Mui E, Suzuki Y, Sa Q, Bi S, Cardona N, Verma SK, Frazeck L, Reardon CA, Sidney J, Alexander J, Sette A, Vedvick T, Fox C, Guderian JA, Reed S, Roberts CW, McLeod R.

JCI Insight. 2016 Sep 22;1(15):e85955.

31.

Screening, brief intervention, and referral to treatment: a 5-year comparison of staff buy-in.

Kaplan B, Hopkins E, Taecker M, Broderick KB.

Am J Emerg Med. 2016 Nov;34(11):2232-2234. doi: 10.1016/j.ajem.2016.08.012. Epub 2016 Aug 9. No abstract available.

PMID:
27653212
32.

Direct Hospital Cost of Outcome Pathways in Implant-Based Reconstruction with Acellular Dermal Matrices.

Qureshi AA, Broderick K, Funk S, Reaven N, Tenenbaum MM, Myckatyn TM.

Plast Reconstr Surg Glob Open. 2016 Aug 9;4(8):e831. doi: 10.1097/GOX.0000000000000848. eCollection 2016 Aug.

33.

Uneventful versus Successful Reconstruction and Outcome Pathways in Implant-Based Breast Reconstruction with Acellular Dermal Matrices.

Qureshi AA, Broderick KP, Belz J, Funk S, Reaven N, Brandt KE, Tenenbaum MM, Margenthaler JA, Aft RL, Myckatyn TM.

Plast Reconstr Surg. 2016 Aug;138(2):173e-83e. doi: 10.1097/PRS.0000000000002402.

PMID:
27465177
34.

Health and wellness among emergency physicians: results of the 2014 ABEM longitudinal study.

Marco CA, Broderick K, Smith-Coggins R, Goyal DG, Joldersma KB, Coombs AB.

Am J Emerg Med. 2016 Aug;34(8):1715-6. doi: 10.1016/j.ajem.2016.06.019. Epub 2016 Jun 6. No abstract available.

PMID:
27321937
35.

Wavefront-optimized surface retreatments of refractive error following previous laser refractive surgery: a retrospective study.

Broderick KM, Sia RK, Ryan DS, Stutzman RD, Mines MJ, Frazier TC, Torres MF, Bower KS.

Eye Vis (Lond). 2016 Feb 11;3:3. doi: 10.1186/s40662-016-0034-x. eCollection 2016.

36.

Outcomes of complex robot-assisted extravesical ureteral reimplantation in the pediatric population.

Arlen AM, Broderick KM, Travers C, Smith EA, Elmore JM, Kirsch AJ.

J Pediatr Urol. 2016 Jun;12(3):169.e1-6. doi: 10.1016/j.jpurol.2015.11.007. Epub 2015 Dec 17.

PMID:
26747012
37.

Impact of Clostridium difficile-associated diarrhea on acute care length of stay, hospital costs, and readmission: A multicenter retrospective study of inpatients, 2009-2011.

Magee G, Strauss ME, Thomas SM, Brown H, Baumer D, Broderick KC.

Am J Infect Control. 2015 Nov;43(11):1148-53. doi: 10.1016/j.ajic.2015.06.004.

38.

Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.

Trimble CL, Morrow MP, Kraynyak KA, Shen X, Dallas M, Yan J, Edwards L, Parker RL, Denny L, Giffear M, Brown AS, Marcozzi-Pierce K, Shah D, Slager AM, Sylvester AJ, Khan A, Broderick KE, Juba RJ, Herring TA, Boyer J, Lee J, Sardesai NY, Weiner DB, Bagarazzi ML.

Lancet. 2015 Nov 21;386(10008):2078-2088. doi: 10.1016/S0140-6736(15)00239-1. Epub 2015 Sep 17.

39.

RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance.

Miyamoto DT, Zheng Y, Wittner BS, Lee RJ, Zhu H, Broderick KT, Desai R, Fox DB, Brannigan BW, Trautwein J, Arora KS, Desai N, Dahl DM, Sequist LV, Smith MR, Kapur R, Wu CL, Shioda T, Ramaswamy S, Ting DT, Toner M, Maheswaran S, Haber DA.

Science. 2015 Sep 18;349(6254):1351-6. doi: 10.1126/science.aab0917.

40.

Emergency Physician Utilization of Alcohol/Substance Screening, Brief Advice and Discharge: A 10-Year Comparison.

Broderick KB, Kaplan B, Martini D, Caruso E.

J Emerg Med. 2015 Oct;49(4):400-7. doi: 10.1016/j.jemermed.2015.05.014. Epub 2015 Jul 30.

PMID:
26234716
41.

Skin Transfection Patterns and Expression Kinetics of Electroporation-Enhanced Plasmid Delivery Using the CELLECTRA-3P, a Portable Next-Generation Dermal Electroporation Device.

Amante DH, Smith TR, Mendoza JM, Schultheis K, McCoy JR, Khan AS, Sardesai NY, Broderick KE.

Hum Gene Ther Methods. 2015 Aug;26(4):134-46. doi: 10.1089/hgtb.2015.020.

42.

Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy.

Flingai S, Plummer EM, Patel A, Shresta S, Mendoza JM, Broderick KE, Sardesai NY, Muthumani K, Weiner DB.

Sci Rep. 2015 Jul 29;5:12616. doi: 10.1038/srep12616.

43.

Pilot Validation of a Brief Screen Tool for Substance Use Detection in Emergency Care.

Broderick KB, Richmond MK, Fagan J, Long AW.

J Emerg Med. 2015 Sep;49(3):369-74. doi: 10.1016/j.jemermed.2015.03.011. Epub 2015 Jun 6.

PMID:
26054313
44.

A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin.

McCoy JR, Mendoza JM, Spik KW, Badger C, Gomez AF, Schmaljohn CS, Sardesai NY, Broderick KE.

Hum Vaccin Immunother. 2015;11(3):746-54. doi: 10.4161/21645515.2014.978223.

45.

Frequency and Risk of Marijuana Use among Substance-Using Health Care Patients in Colorado with and without Access to State Legalized Medical Marijuana.

Richmond MK, Pampel FC, Rivera LS, Broderick KB, Reimann B, Fischer L.

J Psychoactive Drugs. 2015 Jan-Mar;47(1):1-9. doi: 10.1080/02791072.2014.991008.

PMID:
25715066
46.

Electroporation-enhanced delivery of nucleic acid vaccines.

Broderick KE, Humeau LM.

Expert Rev Vaccines. 2015 Feb;14(2):195-204. doi: 10.1586/14760584.2015.990890. Epub 2014 Dec 9. Review.

PMID:
25487734
47.

A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin.

McCoy JR, Mendoza JM, Spik KW, Badger C, Gomez AF, Schmaljohn CS, Sardesai NY, Broderick KE.

Hum Vaccin Immunother. 2014;10(10):3039-47. doi: 10.4161/hv.29671. Epub 2014 Nov 21.

48.

Direct transfection of dendritic cells in the epidermis after plasmid delivery enhanced by surface electroporation.

Amante DH, Smith TR, Kiosses BB, Sardesai NY, Humeau LM, Broderick KE.

Hum Gene Ther Methods. 2014 Dec;25(6):315-6. doi: 10.1089/hgtb.2014.061.

49.

A research agenda for gender and substance use disorders in the emergency department.

Choo EK, Beauchamp G, Beaudoin FL, Bernstein E, Bernstein J, Bernstein SL, Broderick KB, Cannon RD, D'Onofrio G, Greenberg MR, Hawk K, Hayes RB, Jacquet GA, Lippmann MJ, Rhodes KV, Watts SH, Boudreaux ED.

Acad Emerg Med. 2014 Dec;21(12):1438-46. doi: 10.1111/acem.12534. Epub 2014 Dec 1.

50.

The intersecting roles of violence, gender, and substance use in the emergency department: a research agenda.

Choo EK, Benz M, Rybarczyk M, Broderick K, Linden J, Boudreaux ED, Ranney ML.

Acad Emerg Med. 2014 Dec;21(12):1447-52. doi: 10.1111/acem.12525. Epub 2014 Nov 24.

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