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Items: 1 to 50 of 162

1.

Serological Evidence for Henipa-like and Filo-like Viruses in Trinidad Bats.

Schulz JE, Seifert SN, Thompson JT, Avanzato V, Sterling SL, Yan L, Letko MC, Matson MJ, Fischer RJ, Tremeau-Bravard A, Seetahal JFR, Ramkissoon V, Foster J, Goldstein T, Anthony SJ, Epstein JH, Laing ED, Broder CC, Carrington CVF, Schountz T, Munster VJ.

J Infect Dis. 2020 Feb 8. pii: jiz648. doi: 10.1093/infdis/jiz648. [Epub ahead of print]

PMID:
32034942
2.

Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study.

Playford EG, Munro T, Mahler SM, Elliott S, Gerometta M, Hoger KL, Jones ML, Griffin P, Lynch KD, Carroll H, El Saadi D, Gilmour ME, Hughes B, Hughes K, Huang E, de Bakker C, Klein R, Scher MG, Smith IL, Wang LF, Lambert SB, Dimitrov DS, Gray PP, Broder CC.

Lancet Infect Dis. 2020 Apr;20(4):445-454. doi: 10.1016/S1473-3099(19)30634-6. Epub 2020 Feb 3.

PMID:
32027842
3.

Resistance of Cynomolgus Monkeys to Nipah and Hendra Virus Disease Is Associated With Cell-Mediated and Humoral Immunity.

Prasad AN, Woolsey C, Geisbert JB, Agans KN, Borisevich V, Deer DJ, Mire CE, Cross RW, Fenton KA, Broder CC, Geisbert TW.

J Infect Dis. 2019 Dec 5. pii: jiz613. doi: 10.1093/infdis/jiz613. [Epub ahead of print]

PMID:
32022850
4.

A Soluble Version of Nipah Virus Glycoprotein G Delivered by Vaccinia Virus MVA Activates Specific CD8 and CD4 T Cells in Mice.

Kalodimou G, Veit S, Jany S, Kalinke U, Broder CC, Sutter G, Volz A.

Viruses. 2019 Dec 24;12(1). pii: E26. doi: 10.3390/v12010026.

5.

A Cross-Reactive Humanized Monoclonal Antibody Targeting Fusion Glycoprotein Function Protects Ferrets Against Lethal Nipah Virus and Hendra Virus Infection.

Mire CE, Chan YP, Borisevich V, Cross RW, Yan L, Agans KN, Dang HV, Veesler D, Fenton KA, Geisbert TW, Broder CC.

J Infect Dis. 2019 Nov 4. pii: jiz515. doi: 10.1093/infdis/jiz515. [Epub ahead of print]

PMID:
31686101
6.

Rousettus aegyptiacus Bats Do Not Support Productive Nipah Virus Replication.

Seifert SN, Letko MC, Bushmaker T, Laing ED, Saturday G, Meade-White K, van Doremalen N, Broder CC, Munster VJ.

J Infect Dis. 2019 Nov 4. pii: jiz429. doi: 10.1093/infdis/jiz429. [Epub ahead of print]

PMID:
31682727
7.

Filovirus-reactive antibodies in humans and bats in Northeast India imply zoonotic spillover.

Dovih P, Laing ED, Chen Y, Low DHW, Ansil BR, Yang X, Shi Z, Broder CC, Smith GJD, Linster M, Ramakrishnan U, Mendenhall IH.

PLoS Negl Trop Dis. 2019 Oct 31;13(10):e0007733. doi: 10.1371/journal.pntd.0007733. eCollection 2019 Oct.

8.

An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections.

Dang HV, Chan YP, Park YJ, Snijder J, Da Silva SC, Vu B, Yan L, Feng YR, Rockx B, Geisbert TW, Mire CE, Broder CC, Veesler D.

Nat Struct Mol Biol. 2019 Oct;26(10):980-987. doi: 10.1038/s41594-019-0308-9. Epub 2019 Sep 30.

9.

Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus.

Laing ED, Navaratnarajah CK, Cheliout Da Silva S, Petzing SR, Xu Y, Sterling SL, Marsh GA, Wang LF, Amaya M, Nikolov DB, Cattaneo R, Broder CC, Xu K.

Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20707-20715. doi: 10.1073/pnas.1911773116. Epub 2019 Sep 23.

10.

Cytokine Effects on the Entry of Filovirus Envelope Pseudotyped Virus-Like Particles into Primary Human Macrophages.

Stantchev TS, Zack-Taylor A, Mattson N, Strebel K, Broder CC, Clouse KA.

Viruses. 2019 Sep 23;11(10). pii: E889. doi: 10.3390/v11100889.

11.

Optimization and diagnostic evaluation of monoclonal antibody-based blocking ELISA formats for detection of neutralizing antibodies to Hendra virus in mammalian sera.

Di Rubbo A, McNabb L, Klein R, White JR, Colling A, Dimitrov DS, Broder CC, Middleton D, Lunt RA.

J Virol Methods. 2019 Dec;274:113731. doi: 10.1016/j.jviromet.2019.113731. Epub 2019 Sep 9.

PMID:
31513861
12.

Disentangling serology to elucidate henipa- and filovirus transmission in Madagascar fruit bats.

Brook CE, Ranaivoson HC, Broder CC, Cunningham AA, Héraud JM, Peel AJ, Gibson L, Wood JLN, Metcalf CJ, Dobson AP.

J Anim Ecol. 2019 Jul;88(7):1001-1016. doi: 10.1111/1365-2656.12985. Epub 2019 Apr 15.

PMID:
30908623
13.

Enhanced Autophagy Contributes to Reduced Viral Infection in Black Flying Fox Cells.

Laing ED, Sterling SL, Weir DL, Beauregard CR, Smith IL, Larsen SE, Wang LF, Snow AL, Schaefer BC, Broder CC.

Viruses. 2019 Mar 14;11(3). pii: E260. doi: 10.3390/v11030260.

14.

Rescue and characterization of recombinant cedar virus, a non-pathogenic Henipavirus species.

Laing ED, Amaya M, Navaratnarajah CK, Feng YR, Cattaneo R, Wang LF, Broder CC.

Virol J. 2018 Mar 27;15(1):56. doi: 10.1186/s12985-018-0964-0.

15.

Support for viral persistence in bats from age-specific serology and models of maternal immunity.

Peel AJ, Baker KS, Hayman DTS, Broder CC, Cunningham AA, Fooks AR, Garnier R, Wood JLN, Restif O.

Sci Rep. 2018 Mar 1;8(1):3859. doi: 10.1038/s41598-018-22236-6.

16.

A network approach for provisional assay recognition of a Hendra virus antibody ELISA: test validation with low sample numbers from infected horses.

Colling A, Lunt R, Bergfeld J, McNabb L, Halpin K, Juzva S, Newberry K, Morrissy C, Loomes C, Warner S, Diallo I, Kirkland P, Broder CC, Carlile G, Loh MH, Waugh C, Wright L, Watson J, Eagles D, Zuelke K, McCullough S, Daniels P.

J Vet Diagn Invest. 2018 May;30(3):362-369. doi: 10.1177/1040638718760102. Epub 2018 Feb 21.

17.

Serologic Evidence of Fruit Bat Exposure to Filoviruses, Singapore, 2011-2016.

Laing ED, Mendenhall IH, Linster M, Low DHW, Chen Y, Yan L, Sterling SL, Borthwick S, Neves ES, Lim JSL, Skiles M, Lee BPY, Wang LF, Broder CC, Smith GJD.

Emerg Infect Dis. 2018 Jan;24(1):114-117. doi: 10.3201/eid2401.170401.

18.

Protection against henipaviruses in swine requires both, cell-mediated and humoral immune response.

Pickering BS, Hardham JM, Smith G, Weingartl ET, Dominowski PJ, Foss DL, Mwangi D, Broder CC, Roth JA, Weingartl HM.

Vaccine. 2016 Sep 14;34(40):4777-86. doi: 10.1016/j.vaccine.2016.08.028. Epub 2016 Aug 17.

19.

Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy.

Mire CE, Satterfield BA, Geisbert JB, Agans KN, Borisevich V, Yan L, Chan YP, Cross RW, Fenton KA, Broder CC, Geisbert TW.

Sci Rep. 2016 Aug 3;6:30916. doi: 10.1038/srep30916.

20.

Hendra virus and Nipah virus animal vaccines.

Broder CC, Weir DL, Reid PA.

Vaccine. 2016 Jun 24;34(30):3525-34. doi: 10.1016/j.vaccine.2016.03.075. Epub 2016 May 4.

21.

The equine Hendra virus vaccine remains a highly effective preventative measure against infection in horses and humans: 'The imperative to develop a human vaccine for the Hendra virus in Australia'.

Peel AJ, Field HE, Reid PA, Plowright RK, Broder CC, Skerratt LF, Hayman DT, Restif O, Taylor M, Martin G, Crameri G, Smith I, Baker M, Marsh GA, Barr J, Breed AC, Wood JL, Dhand N, Toribio JA, Cunningham AA, Fulton I, Bryden WL, Secombe C, Wang LF.

Infect Ecol Epidemiol. 2016 May 4;6:31658. doi: 10.3402/iee.v6.31658. eCollection 2016. No abstract available.

22.

Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly.

Xu K, Chan YP, Bradel-Tretheway B, Akyol-Ataman Z, Zhu Y, Dutta S, Yan L, Feng Y, Wang LF, Skiniotis G, Lee B, Zhou ZH, Broder CC, Aguilar HC, Nikolov DB.

PLoS Pathog. 2015 Dec 8;11(12):e1005322. doi: 10.1371/journal.ppat.1005322. eCollection 2015 Dec.

23.

Escape From Monoclonal Antibody Neutralization Affects Henipavirus Fitness In Vitro and In Vivo.

Borisevich V, Lee B, Hickey A, DeBuysscher B, Broder CC, Feldmann H, Rockx B.

J Infect Dis. 2016 Feb 1;213(3):448-55. doi: 10.1093/infdis/jiv449. Epub 2015 Sep 10.

24.

Serological evidence of henipavirus exposure in cattle, goats and pigs in Bangladesh.

Chowdhury S, Khan SU, Crameri G, Epstein JH, Broder CC, Islam A, Peel AJ, Barr J, Daszak P, Wang LF, Luby SP.

PLoS Negl Trop Dis. 2014 Nov 20;8(11):e3302. doi: 10.1371/journal.pntd.0003302. eCollection 2014 Nov.

25.

Therapeutic treatment of Nipah virus infection in nonhuman primates with a neutralizing human monoclonal antibody.

Geisbert TW, Mire CE, Geisbert JB, Chan YP, Agans KN, Feldmann F, Fenton KA, Zhu Z, Dimitrov DS, Scott DP, Bossart KN, Feldmann H, Broder CC.

Sci Transl Med. 2014 Jun 25;6(242):242ra82. doi: 10.1126/scitranslmed.3008929.

26.

Immunization of rabbits with highly purified, soluble, trimeric human immunodeficiency virus type 1 envelope glycoprotein induces a vigorous B cell response and broadly cross-reactive neutralization.

Quinnan GV Jr, Onabajo O, Zhang P, Yan L, Mattapallil JJ, Zhang Z, Dong M, Lu M, Montefiori D, LaBranche C, Broder CC.

PLoS One. 2014 May 20;9(5):e98060. doi: 10.1371/journal.pone.0098060. eCollection 2014.

27.
28.

Hendra virus vaccine, a one health approach to protecting horse, human, and environmental health.

Middleton D, Pallister J, Klein R, Feng YR, Haining J, Arkinstall R, Frazer L, Huang JA, Edwards N, Wareing M, Elhay M, Hashmi Z, Bingham J, Yamada M, Johnson D, White J, Foord A, Heine HG, Marsh GA, Broder CC, Wang LF.

Emerg Infect Dis. 2014 Mar;20(3):372-9. doi: 10.3201/eid2003.131159.

29.

Recent observations on Australian bat lyssavirus tropism and viral entry.

Weir DL, Annand EJ, Reid PA, Broder CC.

Viruses. 2014 Feb 19;6(2):909-26. doi: 10.3390/v6020909. Review.

30.

A recombinant Hendra virus G glycoprotein subunit vaccine protects nonhuman primates against Hendra virus challenge.

Mire CE, Geisbert JB, Agans KN, Feng YR, Fenton KA, Bossart KN, Yan L, Chan YP, Broder CC, Geisbert TW.

J Virol. 2014 May;88(9):4624-31. doi: 10.1128/JVI.00005-14. Epub 2014 Feb 12.

31.

Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assay.

Elshabrawy HA, Fan J, Haddad CS, Ratia K, Broder CC, Caffrey M, Prabhakar BS.

J Virol. 2014 Apr;88(8):4353-65. doi: 10.1128/JVI.03050-13. Epub 2014 Feb 5.

32.

Continent-wide panmixia of an African fruit bat facilitates transmission of potentially zoonotic viruses.

Peel AJ, Sargan DR, Baker KS, Hayman DTS, Barr JA, Crameri G, Suu-Ire R, Broder CC, Lembo T, Wang LF, Fooks AR, Rossiter SJ, Wood JLN, Cunningham AA.

Nat Commun. 2013;4:2770. doi: 10.1038/ncomms3770.

33.

Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody.

Xu K, Rockx B, Xie Y, DeBuysscher BL, Fusco DL, Zhu Z, Chan YP, Xu Y, Luu T, Cer RZ, Feldmann H, Mokashi V, Dimitrov DS, Bishop-Lilly KA, Broder CC, Nikolov DB.

PLoS Pathog. 2013;9(10):e1003684. doi: 10.1371/journal.ppat.1003684. Epub 2013 Oct 10.

34.

Viral antibody dynamics in a chiropteran host.

Baker KS, Suu-Ire R, Barr J, Hayman DT, Broder CC, Horton DL, Durrant C, Murcia PR, Cunningham AA, Wood JL.

J Anim Ecol. 2014 Mar;83(2):415-28. doi: 10.1111/1365-2656.12153. Epub 2013 Nov 13.

35.

Paramyxovirus entry.

Bossart KN, Fusco DL, Broder CC.

Adv Exp Med Biol. 2013;790:95-127. doi: 10.1007/978-1-4614-7651-1_6. Review.

PMID:
23884588
36.

Vaccination of ferrets with a recombinant G glycoprotein subunit vaccine provides protection against Nipah virus disease for over 12 months.

Pallister JA, Klein R, Arkinstall R, Haining J, Long F, White JR, Payne J, Feng YR, Wang LF, Broder CC, Middleton D.

Virol J. 2013 Jul 16;10:237. doi: 10.1186/1743-422X-10-237.

37.

Host cell tropism mediated by Australian bat lyssavirus envelope glycoproteins.

Weir DL, Smith IL, Bossart KN, Wang LF, Broder CC.

Virology. 2013 Sep;444(1-2):21-30. doi: 10.1016/j.virol.2013.06.016. Epub 2013 Jul 10.

38.

A treatment for and vaccine against the deadly Hendra and Nipah viruses.

Broder CC, Xu K, Nikolov DB, Zhu Z, Dimitrov DS, Middleton D, Pallister J, Geisbert TW, Bossart KN, Wang LF.

Antiviral Res. 2013 Oct;100(1):8-13. doi: 10.1016/j.antiviral.2013.06.012. Epub 2013 Jul 6. Review.

39.

Use of cross-reactive serological assays for detecting novel pathogens in wildlife: assessing an appropriate cutoff for henipavirus assays in African bats.

Peel AJ, McKinley TJ, Baker KS, Barr JA, Crameri G, Hayman DT, Feng YR, Broder CC, Wang LF, Cunningham AA, Wood JL.

J Virol Methods. 2013 Nov;193(2):295-303. doi: 10.1016/j.jviromet.2013.06.030. Epub 2013 Jul 5.

PMID:
23835034
40.

Passive immunization and active vaccination against Hendra and Nipah viruses.

Broder CC.

Dev Biol (Basel). 2013;135:125-38. doi: 10.1159/000171017. Epub 2013 May 14.

PMID:
23689890
41.

Human monoclonal antibodies as candidate therapeutics against emerging viruses and HIV-1.

Zhu Z, Prabakaran P, Chen W, Broder CC, Gong R, Dimitrov DS.

Virol Sin. 2013 Apr;28(2):71-80. doi: 10.1007/s12250-013-3313-x. Epub 2013 Apr 11. Review.

42.

Neutralizing antibody responses in macaques induced by human immunodeficiency virus type 1 monovalent or trivalent envelope glycoproteins.

Quinnan GV Jr, Zhang P, Dong M, Chen H, Feng YR, Lewis M, Broder CC.

PLoS One. 2013;8(3):e59803. doi: 10.1371/journal.pone.0059803. Epub 2013 Mar 22.

43.

Recombinant Hendra viruses expressing a reporter gene retain pathogenicity in ferrets.

Marsh GA, Virtue ER, Smith I, Todd S, Arkinstall R, Frazer L, Monaghan P, Smith GA, Broder CC, Middleton D, Wang LF.

Virol J. 2013 Mar 25;10:95. doi: 10.1186/1743-422X-10-95.

44.

Comparative analysis of bat genomes provides insight into the evolution of flight and immunity.

Zhang G, Cowled C, Shi Z, Huang Z, Bishop-Lilly KA, Fang X, Wynne JW, Xiong Z, Baker ML, Zhao W, Tachedjian M, Zhu Y, Zhou P, Jiang X, Ng J, Yang L, Wu L, Xiao J, Feng Y, Chen Y, Sun X, Zhang Y, Marsh GA, Crameri G, Broder CC, Frey KG, Wang LF, Wang J.

Science. 2013 Jan 25;339(6118):456-60. doi: 10.1126/science.1230835. Epub 2012 Dec 20.

45.

Cell-type specific requirements for thiol/disulfide exchange during HIV-1 entry and infection.

Stantchev TS, Paciga M, Lankford CR, Schwartzkopff F, Broder CC, Clouse KA.

Retrovirology. 2012 Dec 3;9:97. doi: 10.1186/1742-4690-9-97.

46.

New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2.

Xu K, Chan YP, Rajashankar KR, Khetawat D, Yan L, Kolev MV, Broder CC, Nikolov DB.

PLoS One. 2012;7(11):e48742. doi: 10.1371/journal.pone.0048742. Epub 2012 Nov 5.

47.

Biochemical, conformational, and immunogenic analysis of soluble trimeric forms of henipavirus fusion glycoproteins.

Chan YP, Lu M, Dutta S, Yan L, Barr J, Flora M, Feng YR, Xu K, Nikolov DB, Wang LF, Skiniotis G, Broder CC.

J Virol. 2012 Nov;86(21):11457-71. doi: 10.1128/JVI.01318-12. Epub 2012 Aug 22.

48.

A Hendra virus G glycoprotein subunit vaccine protects African green monkeys from Nipah virus challenge.

Bossart KN, Rockx B, Feldmann F, Brining D, Scott D, LaCasse R, Geisbert JB, Feng YR, Chan YP, Hickey AC, Broder CC, Feldmann H, Geisbert TW.

Sci Transl Med. 2012 Aug 8;4(146):146ra107. doi: 10.1126/scitranslmed.3004241.

49.

Antigen capture ELISA system for henipaviruses using polyclonal antibodies obtained by DNA immunization.

Kaku Y, Noguchi A, Marsh GA, Barr JA, Okutani A, Hotta K, Bazartseren B, Broder CC, Yamada A, Inoue S, Wang LF.

Arch Virol. 2012 Aug;157(8):1605-9. doi: 10.1007/s00705-012-1338-3. Epub 2012 May 15.

PMID:
22585045
50.

Henipavirus outbreaks to antivirals: the current status of potential therapeutics.

Broder CC.

Curr Opin Virol. 2012 Apr;2(2):176-87. doi: 10.1016/j.coviro.2012.02.016. Epub 2012 Mar 21. Review.

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