Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 234

1.

Parkinson's Disease: Glucocerebrosidase 1 Mutation Severity Is Associated with CSF Alpha-Synuclein Profiles.

Lerche S, Wurster I, Roeben B, Zimmermann M, Riebenbauer B, Deuschle C, Hauser AK, Schulte C, Berg D, Maetzler W, Waniek K, Lachmann I, Liepelt-Scarfone I, Gasser T, Brockmann K.

Mov Disord. 2019 Oct 30. doi: 10.1002/mds.27884. [Epub ahead of print]

PMID:
31670439
2.

Deficient knowledge in adult care as an incentives for founding Turner centers in Germany.

Kahlert E, Blaschke M, Brockmann K, Freiberg C, Janßen OE, Stahnke N, Strik D, Merkel M, Mann A, Liesenkötter KP, Siggelkow H.

Endocr Connect. 2019 Oct 1. pii: EC-19-0418.R1. doi: 10.1530/EC-19-0418. [Epub ahead of print]

3.

A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain.

Huang J, Estacion M, Zhao P, Dib-Hajj FB, Schulman B, Abicht A, Kurth I, Brockmann K, Waxman SG, Dib-Hajj SD.

Front Neurosci. 2019 Sep 3;13:918. doi: 10.3389/fnins.2019.00918. eCollection 2019.

4.

Do longitudinal cerebrospinal fluid profiles correspond to postmortem brain pathology in LRRK2 Parkinson's disease?

Wurster I, Lerche S, Hauser AK, Schulte C, Lachmann I, Beschorner R, Neumann M, Brockmann K.

Eur J Neurol. 2019 Aug 17. doi: 10.1111/ene.14060. [Epub ahead of print] No abstract available.

PMID:
31420996
5.

Cancer outcomes among Parkinson's disease patients with leucine rich repeat kinase 2 mutations, idiopathic Parkinson's disease patients, and nonaffected controls.

Agalliu I, Ortega RA, Luciano MS, Mirelman A, Pont-Sunyer C, Brockmann K, Vilas D, Tolosa E, Berg D, Warø B, Glickman A, Raymond D, Inzelberg R, Ruiz-Martinez J, Mondragon E, Friedman E, Hassin-Baer S, Alcalay RN, Mejia-Santana H, Aasly J, Foroud T, Marder K, Giladi N, Bressman S, Saunders-Pullman R.

Mov Disord. 2019 Sep;34(9):1392-1398. doi: 10.1002/mds.27807. Epub 2019 Jul 26.

6.

Orthostatic hypotension as a risk factor for longitudinal deterioration of cognitive function in the elderly.

Zimmermann M, Wurster I, Lerche S, Roeben B, Machetanz G, Sünkel U, von Thaler AK, Eschweiler G, Fallgatter AJ, Maetzler W, Berg D, Brockmann K.

Eur J Neurol. 2019 Jul 25. doi: 10.1111/ene.14050. [Epub ahead of print]

PMID:
31342593
7.

Gait analysis with wearables predicts conversion to parkinson disease.

Del Din S, Elshehabi M, Galna B, Hobert MA, Warmerdam E, Suenkel U, Brockmann K, Metzger F, Hansen C, Berg D, Rochester L, Maetzler W.

Ann Neurol. 2019 Sep;86(3):357-367. doi: 10.1002/ana.25548. Epub 2019 Jul 27.

PMID:
31294853
8.

[Personalized treatment of Parkinson's disease].

Brockmann K, Gasser T.

Nervenarzt. 2019 Aug;90(8):767-772. doi: 10.1007/s00115-019-0748-9. Review. German.

PMID:
31243506
9.

Dementia with lewy bodies: GBA1 mutations are associated with cerebrospinal fluid alpha-synuclein profile.

Lerche S, Machetanz G, Wurster I, Roeben B, Zimmermann M, Pilotto A, Preische O, Stransky E, Deuschle C, Hauser AK, Schulte C, Lachmann I, Waniek K, Gasser T, Berg D, Maetzler W, Brockmann K.

Mov Disord. 2019 Jul;34(7):1069-1073. doi: 10.1002/mds.27731. Epub 2019 Jun 12.

PMID:
31189032
10.

Systematic Ion Source Parameter Assessment by Automated Determination of the Distribution of Ion Acceptance (DIA) Using APLI.

Wißdorf W, Lorenz M, Brockmann K, Benter T.

J Am Soc Mass Spectrom. 2019 Jul;30(7):1262-1275. doi: 10.1007/s13361-019-02190-x. Epub 2019 May 8.

PMID:
31069698
11.

Structural brain anomalies in patients with FOXG1 syndrome and in Foxg1+/- mice.

Pringsheim M, Mitter D, Schröder S, Warthemann R, Plümacher K, Kluger G, Baethmann M, Bast T, Braun S, Büttel HM, Conover E, Courage C, Datta AN, Eger A, Grebe TA, Hasse-Wittmer A, Heruth M, Höft K, Kaindl AM, Karch S, Kautzky T, Korenke GC, Kruse B, Lutz RE, Omran H, Patzer S, Philippi H, Ramsey K, Rating T, Rieß A, Schimmel M, Westman R, Zech FM, Zirn B, Ulmke PA, Sokpor G, Tuoc T, Leha A, Staudt M, Brockmann K.

Ann Clin Transl Neurol. 2019 Mar 3;6(4):655-668. doi: 10.1002/acn3.735. eCollection 2019 Apr.

12.

The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.

Funk N, Munz M, Ott T, Brockmann K, Wenninger-Weinzierl A, Kühn R, Vogt-Weisenhorn D, Giesert F, Wurst W, Gasser T, Biskup S.

Sci Rep. 2019 Mar 14;9(1):4515. doi: 10.1038/s41598-019-40808-y.

13.

Erosive tooth wear and caries experience in children and adolescents with obesity.

Tschammler C, Simon A, Brockmann K, Röbl M, Wiegand A.

J Dent. 2019 Apr;83:77-86. doi: 10.1016/j.jdent.2019.02.005. Epub 2019 Feb 27.

PMID:
30825568
14.

Dermal Phospho-Alpha-Synuclein Deposition in Patients With Parkinson's Disease and Mutation of the Glucocerebrosidase Gene.

Doppler K, Brockmann K, Sedghi A, Wurster I, Volkmann J, Oertel WH, Sommer C.

Front Neurol. 2018 Dec 17;9:1094. doi: 10.3389/fneur.2018.01094. eCollection 2018.

15.

REM sleep behaviour disorder (RBD): risk for Parkinsonism and executive dysfunction in elderly.

Lerche S, Brockmann K.

Oncotarget. 2018 Dec 4;9(95):36732-36733. doi: 10.18632/oncotarget.26417. eCollection 2018 Dec 4. No abstract available.

16.

Assessment of cognitive-driven activity of daily living impairment in non-demented Parkinson's patients.

Becker S, Bäumer A, Maetzler W, Nussbaum S, Timmers M, Van Nueten L, Salvadore G, Zaunbrecher D, Roeben B, Brockmann K, Streffer J, Berg D, Liepelt-Scarfone I.

J Neuropsychol. 2018 Oct 15. doi: 10.1111/jnp.12173. [Epub ahead of print]

PMID:
30320954
17.

Parkinson's disease: evolution of cognitive impairment and CSF Aβ1-42 profiles in a prospective longitudinal study.

Lerche S, Wurster I, Röben B, Machetanz G, Zimmermann M, Bernhard F, Stransky E, Deuschle C, Schulte C, Hansson O, Zetterberg H, Gasser T, Berg D, Maetzler W, Brockmann K.

J Neurol Neurosurg Psychiatry. 2019 Feb;90(2):165-170. doi: 10.1136/jnnp-2018-318956. Epub 2018 Sep 25.

PMID:
30254084
18.

Arm swing asymmetry in overground walking.

Killeen T, Elshehabi M, Filli L, Hobert MA, Hansen C, Rieger D, Brockmann K, Nussbaum S, Zörner B, Bolliger M, Curt A, Berg D, Maetzler W.

Sci Rep. 2018 Aug 24;8(1):12803. doi: 10.1038/s41598-018-31151-9.

19.

Polygenic load: Earlier disease onset but similar longitudinal progression in Parkinson's disease.

Lerche S, Liepelt-Scarfone I, Wurster I, Schulte C, Schäffer E, Röben B, Machetanz G, Zimmermann M, Akbas S, Hauser AK, Gasser T, Maetzler W, Berg D, Brockmann K.

Mov Disord. 2018 Aug;33(8):1349-1353. doi: 10.1002/mds.27427. Epub 2018 Aug 22.

PMID:
30132985
20.

Homozygosity for the c.428delG variant in KIAA0586 in a healthy individual: implications for molecular testing in patients with Joubert syndrome.

Pauli S, Altmüller J, Schröder S, Ohlenbusch A, Dreha-Kulaczewski S, Bergmann C, Nürnberg P, Thiele H, Li Y, Wollnik B, Brockmann K.

J Med Genet. 2019 Apr;56(4):261-264. doi: 10.1136/jmedgenet-2018-105470. Epub 2018 Aug 17.

PMID:
30120217
21.

Patient's perception: shorter and more severe prodromal phase in GBA-associated PD.

Zimmermann M, Gaenslen A, Prahl K, Srulijes K, Hauser AK, Schulte C, Csoti I, Berg D, Brockmann K.

Eur J Neurol. 2019 Apr;26(4):694-698. doi: 10.1111/ene.13776. Epub 2018 Sep 14.

PMID:
30107068
22.

Deterioration of executive dysfunction in elderly with REM sleep behavior disorder (RBD).

Lerche S, Machetanz G, Roeben B, Wurster I, Zimmermann M, von Thaler AK, Liepelt-Scarfone I, Eschweiler GW, Fallgatter A, Metzger F, Maetzler W, Berg D, Brockmann K.

Neurobiol Aging. 2018 Oct;70:242-246. doi: 10.1016/j.neurobiolaging.2018.06.029. Epub 2018 Jun 30.

PMID:
30048891
23.

Serum neurofilament light chain is increased in hereditary spastic paraplegias.

Wilke C, Rattay TW, Hengel H, Zimmermann M, Brockmann K, Schöls L, Kuhle J, Schüle R, Synofzik M.

Ann Clin Transl Neurol. 2018 May 21;5(7):876-882. doi: 10.1002/acn3.583. eCollection 2018 Jul.

24.

Validation of a novel Montreal Cognitive Assessment scoring algorithm in non-demented Parkinson's disease patients.

Sulzer P, Becker S, Maetzler W, Kalbe E, van Nueten L, Timmers M, Machetanz G, Streffer J, Salvadore G, Scholz E, Tkaczynska Z, Brockmann K, Berg D, Liepelt-Scarfone I.

J Neurol. 2018 Sep;265(9):1976-1984. doi: 10.1007/s00415-018-8942-4. Epub 2018 Jun 23.

PMID:
29936665
25.

Biallelic Parkin (PARK2) mutations can cause a bvFTD phenotype without clinically relevant parkinsonism.

Zimmermann M, Wilke C, Schulte C, Hoffmann J, Klopfer J, Reimold M, Brockmann K, Synofzik M.

Parkinsonism Relat Disord. 2018 Oct;55:145-147. doi: 10.1016/j.parkreldis.2018.06.006. Epub 2018 Jun 6. No abstract available.

PMID:
29910155
26.

Serum neurofilament light is increased in multiple system atrophy of cerebellar type and in repeat-expansion spinocerebellar ataxias: a pilot study.

Wilke C, Bender F, Hayer SN, Brockmann K, Schöls L, Kuhle J, Synofzik M.

J Neurol. 2018 Jul;265(7):1618-1624. doi: 10.1007/s00415-018-8893-9. Epub 2018 May 8.

PMID:
29737427
27.

Age- and sex-related heterogeneity in prodromal Parkinson's disease.

Heinzel S, Kasten M, Behnke S, Vollstedt EJ, Klein C, Hagenah J, Pausch C, Heilmann R, Brockmann K, Suenkel U, Yilmaz R, Liepelt-Scarfone I, Walter U, Berg D.

Mov Disord. 2018 Jul;33(6):1025-1027. doi: 10.1002/mds.27349. Epub 2018 Mar 23. No abstract available.

PMID:
29570852
28.

Effects of Levetiracetam and Sulthiame on EEG in benign epilepsy with centrotemporal spikes: A randomized controlled trial.

Tacke M, Borggraefe I, Gerstl L, Heinen F, Vill K, Bonfert M, Bast T; HEAD Study group, Neubauer BA, Baumeister F, Baethmann M, Bentele K, Blank C, Blank HM, Bode H, Bosch F, Brandl U, Brockmann K, Dahlem P, Ernst JP, Feldmann E, Fiedler A, Gerigk M, Heß S, Hikel C, Hoffmann HG, Kieslich M, Klepper J, Kluger G, Koch H, Koch W, Korinthenberg R, Krois I, Kühne H, Kurlemann G, Mandl M, Mause U, Navratil P, Opp J, Penzien J, Prietsch V, Quattländer A, Rating D, Schara U, Shamdeen MG, Sprinz A, Wendker-Magrabi H, Stephani U, Muhle H, Straßburg HM, Töpke B, Trollmann R, Tuschen-Hofstätter E, Waltz S, Weber G, Wien FU, Wolff M, Polster T, Freitag H, Sönmez Ö, Reinhardt K, Traus M, Hoovey Z.

Seizure. 2018 Mar;56:115-120. doi: 10.1016/j.seizure.2018.01.015. Epub 2018 Feb 3.

29.

Effect of physical activity on cognitive flexibility, depression and RBD in healthy elderly.

Lerche S, Gutfreund A, Brockmann K, Hobert MA, Wurster I, Sünkel U, Eschweiler GW, Metzger FG, Maetzler W, Berg D.

Clin Neurol Neurosurg. 2018 Feb;165:88-93. doi: 10.1016/j.clineuro.2018.01.008. Epub 2018 Jan 9.

PMID:
29331872
30.

Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.

Fan Y, Howden AJM, Sarhan AR, Lis P, Ito G, Martinez TN, Brockmann K, Gasser T, Alessi DR, Sammler EM.

Biochem J. 2018 Jan 2;475(1):23-44. doi: 10.1042/BCJ20170803.

31.

SNPs in Aβ clearance proteins: Lower CSF Aβ1-42 levels and earlier onset of dementia in PD.

Brockmann K, Lerche S, Dilger SS, Stirnkorb JG, Apel A, Hauser AK, Liepelt-Scarfone I, Berg D, Gasser T, Schulte C, Maetzler W.

Neurology. 2017 Dec 5;89(23):2335-2340. doi: 10.1212/WNL.0000000000004705. Epub 2017 Nov 8.

PMID:
29117956
32.

Cognitive impairment in Glucocerebrosidase (GBA)-associated PD: Not primarily associated with cerebrospinal fluid Abeta and Tau profiles.

Lerche S, Schulte C, Srulijes K, Pilotto A, Rattay TW, Hauser AK, Stransky E, Deuschle C, Csoti I, Lachmann I, Zetterberg H, Liepelt-Scarfone I, Gasser T, Maetzler W, Berg D, Brockmann K.

Mov Disord. 2017 Dec;32(12):1780-1783. doi: 10.1002/mds.27199. Epub 2017 Nov 2.

PMID:
29094781
33.

Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease.

Fitzgerald JC, Zimprich A, Carvajal Berrio DA, Schindler KM, Maurer B, Schulte C, Bus C, Hauser AK, Kübler M, Lewin R, Bobbili DR, Schwarz LM, Vartholomaiou E, Brockmann K, Wüst R, Madlung J, Nordheim A, Riess O, Martins LM, Glaab E, May P, Schenke-Layland K, Picard D, Sharma M, Gasser T, Krüger R.

Brain. 2017 Sep 1;140(9):2444-2459. doi: 10.1093/brain/awx202.

PMID:
29050400
34.

Cognitive changes in prodromal Parkinson's disease: A review.

Fengler S, Liepelt-Scarfone I, Brockmann K, Schäffer E, Berg D, Kalbe E.

Mov Disord. 2017 Dec;32(12):1655-1666. doi: 10.1002/mds.27135. Epub 2017 Oct 5. Review.

PMID:
28980730
35.

Progression of prodromal motor and non-motor symptoms in the premotor phase study - 2-year follow-up data.

Liepelt-Scarfone I, Brändle B, Yilmaz R, Gauss K, Schaeffer E, Timmers M, Wurster I, Brockmann K, Maetzler W, Van Nueten L, Streffer JR, Berg D.

Eur J Neurol. 2017 Nov;24(11):1369-1374. doi: 10.1111/ene.13397. Epub 2017 Sep 5.

PMID:
28872736
36.

Distinct metabolomic signature in cerebrospinal fluid in early parkinson's disease.

Trezzi JP, Galozzi S, Jaeger C, Barkovits K, Brockmann K, Maetzler W, Berg D, Marcus K, Betsou F, Hiller K, Mollenhauer B.

Mov Disord. 2017 Oct;32(10):1401-1408. doi: 10.1002/mds.27132. Epub 2017 Aug 26.

PMID:
28843022
37.

Dual-Task Performance in GBA Parkinson's Disease.

Srulijes K, Brockmann K, Ogbamicael S, Hobert MA, Hauser AK, Schulte C, Fritzen J, Schwenk M, Gasser T, Berg D, Maetzler W.

Parkinsons Dis. 2017;2017:8582740. doi: 10.1155/2017/8582740. Epub 2017 Jul 27.

38.

FOXG1 syndrome: genotype-phenotype association in 83 patients with FOXG1 variants.

Mitter D, Pringsheim M, Kaulisch M, Plümacher KS, Schröder S, Warthemann R, Abou Jamra R, Baethmann M, Bast T, Büttel HM, Cohen JS, Conover E, Courage C, Eger A, Fatemi A, Grebe TA, Hauser NS, Heinritz W, Helbig KL, Heruth M, Huhle D, Höft K, Karch S, Kluger G, Korenke GC, Lemke JR, Lutz RE, Patzer S, Prehl I, Hoertnagel K, Ramsey K, Rating T, Rieß A, Rohena L, Schimmel M, Westman R, Zech FM, Zoll B, Malzahn D, Zirn B, Brockmann K.

Genet Med. 2018 Jan;20(1):98-108. doi: 10.1038/gim.2017.75. Epub 2017 Jun 29.

PMID:
28661489
39.

Penetrance estimate of LRRK2 p.G2019S mutation in individuals of non-Ashkenazi Jewish ancestry.

Lee AJ, Wang Y, Alcalay RN, Mejia-Santana H, Saunders-Pullman R, Bressman S, Corvol JC, Brice A, Lesage S, Mangone G, Tolosa E, Pont-Sunyer C, Vilas D, Schüle B, Kausar F, Foroud T, Berg D, Brockmann K, Goldwurm S, Siri C, Asselta R, Ruiz-Martinez J, Mondragón E, Marras C, Ghate T, Giladi N, Mirelman A, Marder K; Michael J. Fox LRRK2 Cohort Consortium.

Mov Disord. 2017 Oct;32(10):1432-1438. doi: 10.1002/mds.27059. Epub 2017 Jun 22.

40.

[Genetic risk variants in Parkinson's disease and other movement disorders].

Brockmann K, Lohmann K.

Nervenarzt. 2017 Jul;88(7):713-719. doi: 10.1007/s00115-017-0348-5. Review. German.

PMID:
28536875
41.

Application of the movement disorder society prodromal Parkinson's disease research criteria in 2 independent prospective cohorts.

Pilotto A, Heinzel S, Suenkel U, Lerche S, Brockmann K, Roeben B, Schaeffer E, Wurster I, Yilmaz R, Liepelt-Scarfone I, von Thaler AK, Metzger FG, Eschweiler GW, Postuma RB, Maetzler W, Berg D.

Mov Disord. 2017 Jul;32(7):1025-1034. doi: 10.1002/mds.27035. Epub 2017 May 16.

PMID:
28509336
42.

[New therapy approaches for Parkinson's disease].

Brockmann K, Berg D.

Nervenarzt. 2017 Apr;88(4):391-396. doi: 10.1007/s00115-017-0299-x. Review. German.

PMID:
28289790
43.

Inflammatory profile discriminates clinical subtypes in LRRK2-associated Parkinson's disease.

Brockmann K, Schulte C, Schneiderhan-Marra N, Apel A, Pont-Sunyer C, Vilas D, Ruiz-Martinez J, Langkamp M, Corvol JC, Cormier F, Knorpp T, Joos TO, Bernard A, Gasser T, Marras C, Schüle B, Aasly JO, Foroud T, Marti-Masso JF, Brice A, Tolosa E, Berg D, Maetzler W.

Eur J Neurol. 2017 Feb;24(2):427-e6. doi: 10.1111/ene.13223.

PMID:
28102045
44.

Prospective longitudinal course of cognition in older subjects with mild parkinsonian signs.

Lerche S, Brockmann K, Pilotto A, Wurster I, Sünkel U, Hobert MA, von Thaler AK, Schulte C, Stoops E, Vanderstichele H, Herbst V, Brix B, Eschweiler GW, Metzger FG, Maetzler W, Berg D.

Alzheimers Res Ther. 2016 Oct 10;8(1):42.

45.

[Transition of Adolescents with Chronic Neurologic Disorders into Adult Health Care].

Albers L, Koch EL, Lingen M, von Kries R, Brockmann K.

Klin Padiatr. 2016 Sep;228(5):251-6. doi: 10.1055/s-0042-111690. Epub 2016 Sep 12. German.

PMID:
27617761
46.

Diagnostic and prognostic value of in vivo proton MR spectroscopy for Zellweger syndrome spectrum patients.

Rosewich H, Dechent P, Krause C, Ohlenbusch A, Brockmann K, Gärtner J.

J Inherit Metab Dis. 2016 Nov;39(6):869-876. Epub 2016 Aug 3.

PMID:
27488561
47.

Nosological delineation of congenital ocular motor apraxia type Cogan: an observational study.

Wente S, Schröder S, Buckard J, Büttel HM, von Deimling F, Diener W, Häussler M, Hübschle S, Kinder S, Kurlemann G, Kretzschmar C, Lingen M, Maroske W, Mundt D, Sánchez-Albisua I, Seeger J, Toelle SP, Boltshauser E, Brockmann K.

Orphanet J Rare Dis. 2016 Jul 29;11(1):104. doi: 10.1186/s13023-016-0486-z.

48.

Broad clinical phenotype in Parkinsonism associated with a base pair deletion in RAB39B and additional POLG variant.

Güldner M, Schulte C, Hauser AK, Gasser T, Brockmann K.

Parkinsonism Relat Disord. 2016 Oct;31:148-150. doi: 10.1016/j.parkreldis.2016.07.005. Epub 2016 Jul 15. No abstract available.

PMID:
27448726
49.

Eight further individuals with intellectual disability and epilepsy carrying bi-allelic CNTNAP2 aberrations allow delineation of the mutational and phenotypic spectrum.

Smogavec M, Cleall A, Hoyer J, Lederer D, Nassogne MC, Palmer EE, Deprez M, Benoit V, Maystadt I, Noakes C, Leal A, Shaw M, Gecz J, Raymond L, Reis A, Shears D, Brockmann K, Zweier C.

J Med Genet. 2016 Dec;53(12):820-827. doi: 10.1136/jmedgenet-2016-103880. Epub 2016 Jul 20.

PMID:
27439707
50.

Erratum to: Gas Flow Dynamics in Inlet Capillaries: Evidence for non Laminar Conditions.

Wißdorf W, Müller D, Brachthäuser Y, Langner M, Derpmann V, Klopotowski S, Polaczek C, Kersten H, Brockmann K, Benter T.

J Am Soc Mass Spectrom. 2016 Sep;27(9):1564. No abstract available.

PMID:
27439409

Supplemental Content

Loading ...
Support Center