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Items: 1 to 50 of 283

1.

The Healthcare Travelling Roadshow: a qualitative study of a rural community engagement initiative in Canada.

Maurice S, Mytting K, Gentles JQ, Roots R, Constantin AG, Kruger SL, Sim S, Brock W, Oyedele O, Soles JA, Snadden D.

Rural Remote Health. 2019 Sep;19(3):5238. doi: 10.22605/RRH5238. Epub 2019 Sep 10.

2.

Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease.

Bezençon J, Beaudoin JJ, Ito K, Fu D, Roth SE, Brock WJ, Brouwer KLR.

Drug Metab Dispos. 2019 Aug;47(8):899-906. doi: 10.1124/dmd.119.086785. Epub 2019 Jun 3.

PMID:
31160314
3.

David Marcus Knight (1936-2018): An Appreciation.

Brock WH.

Ambix. 2019 May-Aug;66(2-3):246-263. doi: 10.1080/00026980.2019.1621499. Epub 2019 May 30.

PMID:
31142217
4.

Introduction to the WEEL values of selected fluorocarbons.

Brock WJ.

Toxicol Ind Health. 2019 Mar;35(3):177-179. doi: 10.1177/0748233719825532. No abstract available.

PMID:
30862295
5.

Altered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney Disease.

Beaudoin JJ, Bezençon J, Cao Y, Mizuno K, Roth SE, Brock WJ, Brouwer KLR.

Drug Metab Dispos. 2019 Feb;47(2):155-163. doi: 10.1124/dmd.118.083907. Epub 2018 Nov 30. Erratum in: Drug Metab Dispos. 2019 Mar;47(3):328.

PMID:
30504136
6.

The Measure of All Things. A History of Analytical Chemistry.

Brock WH.

Ambix. 2018 Oct 22:1. doi: 10.1080/00026980.2018.1534645. [Epub ahead of print] No abstract available.

PMID:
30348061
7.

Bile Acids as Potential Biomarkers to Assess Liver Impairment in Polycystic Kidney Disease.

Brock WJ, Beaudoin JJ, Slizgi JR, Su M, Jia W, Roth SE, Brouwer KLR.

Int J Toxicol. 2018 Mar/Apr;37(2):144-154. doi: 10.1177/1091581818760746.

8.

Association of sporadic and familial Barrett's esophagus with breast cancer.

Chan MQ, Blum AE, Chandar AK, Emmons AMLK, Shindo Y, Brock W, Falk GW, Canto MI, Wang JS, Iyer PG, Shaheen NJ, Grady WM, Abrams JA, Thota PN, Guda KK, Chak A.

Dis Esophagus. 2018 Apr 1;31(4). doi: 10.1093/dote/doy007.

9.

Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus.

Moinova HR, LaFramboise T, Lutterbaugh JD, Chandar AK, Dumot J, Faulx A, Brock W, De la Cruz Cabrera O, Guda K, Barnholtz-Sloan JS, Iyer PG, Canto MI, Wang JS, Shaheen NJ, Thota PN, Willis JE, Chak A, Markowitz SD.

Sci Transl Med. 2018 Jan 17;10(424). pii: eaao5848. doi: 10.1126/scitranslmed.aao5848.

10.

miR-122 Release in Exosomes Precedes Overt Tolvaptan-Induced Necrosis in a Primary Human Hepatocyte Micropatterned Coculture Model.

Mosedale M, Eaddy JS, Trask OJ Jr, Holman NS, Wolf KK, LeCluyse E, Ware BR, Khetani SR, Lu J, Brock WJ, Roth SE, Watkins PB.

Toxicol Sci. 2018 Jan 1;161(1):149-158. doi: 10.1093/toxsci/kfx206.

11.

British School Chemistry Laboratories, 1830-1920.

Brock WH.

Ambix. 2017 Feb;64(1):43-65. doi: 10.1080/00026980.2017.1285853. Epub 2017 Apr 5.

PMID:
28379064
12.

Editor's Highlight: Candidate Risk Factors and Mechanisms for Tolvaptan-Induced Liver Injury Are Identified Using a Collaborative Cross Approach.

Mosedale M, Kim Y, Brock WJ, Roth SE, Wiltshire T, Eaddy JS, Keele GR, Corty RW, Xie Y, Valdar W, Watkins PB.

Toxicol Sci. 2017 Apr 1;156(2):438-454. doi: 10.1093/toxsci/kfw269.

13.

Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors.

Woodhead JL, Brock WJ, Roth SE, Shoaf SE, Brouwer KL, Church R, Grammatopoulos TN, Stiles L, Siler SQ, Howell BA, Mosedale M, Watkins PB, Shoda LK.

Toxicol Sci. 2017 Jan;155(1):61-74. doi: 10.1093/toxsci/kfw193. Epub 2016 Sep 21.

14.

Linkage and related analyses of Barrett's esophagus and its associated adenocarcinomas.

Sun X, Elston R, Falk GW, Grady WM, Faulx A, Mittal SK, Canto MI, Shaheen NJ, Wang JS, Iyer PG, Abrams JA, Willis JE, Guda K, Markowitz S, Barnholtz-Sloan JS, Chandar A, Brock W, Chak A.

Mol Genet Genomic Med. 2016 Mar 14;4(4):407-19. doi: 10.1002/mgg3.211. eCollection 2016 Jul.

15.

Association Between Germline Mutation in VSIG10L and Familial Barrett Neoplasia.

Fecteau RE, Kong J, Kresak A, Brock W, Song Y, Fujioka H, Elston R, Willis JE, Lynch JP, Markowitz SD, Guda K, Chak A.

JAMA Oncol. 2016 Oct 1;2(10):1333-1339. doi: 10.1001/jamaoncol.2016.2054.

16.

Otto Linné Erdmann an Justus von Liebig - kommentierte Briefe von 1853 bis 1867.

Brock WH.

Ambix. 2016 May;63(2):193-194. doi: 10.1080/00026980.2016.1227175. Epub 2016 Sep 2. No abstract available.

PMID:
30463488
17.

Evaluating reproductive decisions as discrete choices under social influence.

Bentley RA, Brock WA, Caiado CC, O'Brien MJ.

Philos Trans R Soc Lond B Biol Sci. 2016 Apr 19;371(1692):20150154. doi: 10.1098/rstb.2015.0154.

18.

Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes.

Lu Y, Slizgi JR, Brouwer KR, Claire RL, Freeman KM, Pan M, Brock WJ, Brouwer KL.

Drug Metab Dispos. 2016 Jun;44(6). pii: dmd.115.067629. doi: 10.1124/dmd.115.067629. Epub 2016 Mar 24.

19.

Improving the Process of Enteral Nutrition Preparation With Milk Technicians: Perceptions of Cost, Time, and Quality.

Brock WW, Cunningham CA, Brandon DH, Hoehn V, Carter B.

Adv Neonatal Care. 2016 Apr;16(2):124-34. doi: 10.1097/ANC.0000000000000253.

PMID:
26954583
20.

Congenital Chylothorax: A Unique Presentation of Nonimmune Hydrops Fetalis in a Preterm Infant.

Brock WW, Bradshaw WT.

Adv Neonatal Care. 2016 Apr;16(2):114-23. doi: 10.1097/ANC.0000000000000257. Review.

PMID:
26945279
21.

Predicting Barrett's Esophagus in Families: An Esophagus Translational Research Network (BETRNet) Model Fitting Clinical Data to a Familial Paradigm.

Sun X, Elston RC, Barnholtz-Sloan JS, Falk GW, Grady WM, Faulx A, Mittal SK, Canto M, Shaheen NJ, Wang JS, Iyer PG, Abrams JA, Tian YD, Willis JE, Guda K, Markowitz SD, Chandar A, Warfe JM, Brock W, Chak A.

Cancer Epidemiol Biomarkers Prev. 2016 May;25(5):727-35. doi: 10.1158/1055-9965.EPI-15-0832. Epub 2016 Feb 29.

22.

Fitness landscapes among many options under social influence.

Caiado CC, Brock WA, Bentley RA, O'Brien MJ.

J Theor Biol. 2016 Sep 21;405:5-16. doi: 10.1016/j.jtbi.2015.12.013. Epub 2016 Feb 2.

PMID:
26851173
23.

Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?

Slizgi JR, Lu Y, Brouwer KR, St Claire RL, Freeman KM, Pan M, Brock WJ, Brouwer KL.

Toxicol Sci. 2016 Jan;149(1):237-50. doi: 10.1093/toxsci/kfv231. Epub 2015 Oct 26.

24.

Age-Related Alterations in Blood Biochemical Characterization of Hepatorenal Function in the PCK Rat: A Model of Polycystic Kidney Disease.

Shimomura Y, Brock WJ, Ito Y, Morishita K.

Int J Toxicol. 2015 Nov-Dec;34(6):479-90. doi: 10.1177/1091581815611075. Epub 2015 Oct 25.

PMID:
26503599
25.

Allowing variance may enlarge the safe operating space for exploited ecosystems.

Carpenter SR, Brock WA, Folke C, van Nes EH, Scheffer M.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):14384-9. doi: 10.1073/pnas.1511804112. Epub 2015 Oct 5.

26.

Scientific conduct... and misconduct.

Genter MB, Brock WJ, Mattes WB.

Toxicol Sci. 2015 Mar;144(1):3-4. No abstract available.

PMID:
25901331
27.

Strengthening the peer review process for the International Journal of Toxicology.

Brock WJ.

Int J Toxicol. 2014 Sep-Oct;33(5):351-2. No abstract available.

PMID:
25513055
28.

Strengthening the peer review process for the International Journal of Toxicology.

Brock WJ.

Int J Toxicol. 2014 Sep-Oct;33(5):351-2. No abstract available.

PMID:
25436270
29.

Estimating a path through a map of decision making.

Brock WA, Bentley RA, O'Brien MJ, Caiado CC.

PLoS One. 2014 Nov 4;9(11):e111022. doi: 10.1371/journal.pone.0111022. eCollection 2014.

30.

Chronic use of maropitant for the management of vomiting and inappetence in cats with chronic kidney disease: a blinded, placebo-controlled clinical trial.

Quimby JM, Brock WT, Moses K, Bolotin D, Patricelli K.

J Feline Med Surg. 2015 Aug;17(8):692-7. doi: 10.1177/1098612X14555441. Epub 2014 Oct 21.

PMID:
25336450
31.

Regime shift in fertilizer commodities indicates more turbulence ahead for food security.

Elser JJ, Elser TJ, Carpenter SR, Brock WA.

PLoS One. 2014 May 1;9(5):e93998. doi: 10.1371/journal.pone.0093998. eCollection 2014.

32.

Authors' response. more on maps, terrains, and behaviors.

Bentley RA, O'Brien MJ, Brock WA.

Behav Brain Sci. 2014 Feb;37(1):105-19.

PMID:
24719904
33.

Early warning signals of ecological transitions: methods for spatial patterns.

Kéfi S, Guttal V, Brock WA, Carpenter SR, Ellison AM, Livina VN, Seekell DA, Scheffer M, van Nes EH, Dakos V.

PLoS One. 2014 Mar 21;9(3):e92097. doi: 10.1371/journal.pone.0092097. eCollection 2014.

34.

Mapping collective behavior in the big-data era.

Bentley RA, O'Brien MJ, Brock WA.

Behav Brain Sci. 2014 Feb;37(1):63-76. doi: 10.1017/S0140525X13000289.

PMID:
24572217
35.

Misrepair of DNA double-strand breaks in patient with unidentified chromosomal fragility syndrome and family history of radiosensitivity.

Alsbeih G, Brock W, Story M.

Int J Radiat Biol. 2014 Jan;90(1):53-9. doi: 10.3109/09553002.2014.859764.

PMID:
24164476
36.

Feline chronic kidney disease is associated with shortened telomeres and increased cellular senescence.

Quimby JM, Maranon DG, Battaglia CL, McLeland SM, Brock WT, Bailey SM.

Am J Physiol Renal Physiol. 2013 Aug 1;305(3):F295-303. doi: 10.1152/ajprenal.00527.2012. Epub 2013 May 29.

37.

Ocular toxicity assessment from systemically administered xenobiotics: considerations in drug development.

Brock WJ, Somps CJ, Torti V, Render JA, Jamison J, Rivera MI.

Int J Toxicol. 2013 May-Jun;32(3):171-88. doi: 10.1177/1091581813484500. Epub 2013 Apr 24. Review.

PMID:
23616147
38.

Word diffusion and climate science.

Bentley RA, Garnett P, O'Brien MJ, Brock WA.

PLoS One. 2012;7(11):e47966. doi: 10.1371/journal.pone.0047966. Epub 2012 Nov 7.

39.

Anticipating critical transitions.

Scheffer M, Carpenter SR, Lenton TM, Bascompte J, Brock W, Dakos V, van de Koppel J, van de Leemput IA, Levin SA, van Nes EH, Pascual M, Vandermeer J.

Science. 2012 Oct 19;338(6105):344-8. doi: 10.1126/science.1225244. Review. Erratum in: Science. 2012 Nov 23;338(6110):1029.

PMID:
23087241
40.

Defining molecular and cellular responses after low and high linear energy transfer radiations to develop biomarkers of carcinogenic risk or therapeutic outcome.

Story M, Ding LH, Brock WA, Ang KK, Alsbeih G, Minna J, Park S, Das A.

Health Phys. 2012 Nov;103(5):596-606. doi: 10.1097/HP.0b013e3182692085. Review.

41.

Early warnings of regime shift when the ecosystem structure is unknown.

Brock WA, Carpenter SR.

PLoS One. 2012;7(9):e45586. doi: 10.1371/journal.pone.0045586. Epub 2012 Sep 21.

42.

Methods for detecting early warnings of critical transitions in time series illustrated using simulated ecological data.

Dakos V, Carpenter SR, Brock WA, Ellison AM, Guttal V, Ives AR, Kéfi S, Livina V, Seekell DA, van Nes EH, Scheffer M.

PLoS One. 2012;7(7):e41010. doi: 10.1371/journal.pone.0041010. Epub 2012 Jul 17.

43.

The in vitro and in vivo genotoxicity of benzocaine: a brief communication.

Brock WJ, Bell TA.

Int J Toxicol. 2012 Jun;31(3):222-7. doi: 10.1177/1091581812442230. Epub 2012 May 2.

PMID:
22556388
45.

Early warnings of unknown nonlinear shifts: a nonparametric approach.

Carpenter SR, Brock WA.

Ecology. 2011 Dec;92(12):2196-201.

PMID:
22352158
46.

Cyclophilin B expression is associated with in vitro radioresistance and clinical outcome after radiotherapy.

Williams PD, Owens CR, Dziegielewski J, Moskaluk CA, Read PW, Larner JM, Story MD, Brock WA, Amundson SA, Lee JK, Theodorescu D.

Neoplasia. 2011 Dec;13(12):1122-31.

47.

Early warnings of regime shifts: a whole-ecosystem experiment.

Carpenter SR, Cole JJ, Pace ML, Batt R, Brock WA, Cline T, Coloso J, Hodgson JR, Kitchell JF, Seekell DA, Smith L, Weidel B.

Science. 2011 May 27;332(6033):1079-82. doi: 10.1126/science.1203672. Epub 2011 Apr 28.

48.

Oral repeat dose and reproductive toxicity of the chlorinated flame retardant Dechlorane Plus.

Brock WJ, Schroeder RE, McKnight CA, VanSteenhouse JL, Nyberg JM.

Int J Toxicol. 2010 Dec;29(6):582-93. doi: 10.1177/1091581810384154. Epub 2010 Oct 19.

PMID:
20959615
49.

c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy.

Peuschel H, Sydlik U, Haendeler J, Büchner N, Stöckmann D, Kroker M, Wirth R, Brock W, Unfried K.

Biol Chem. 2010 Nov;391(11):1327-32. doi: 10.1515/BC.2010.131.

PMID:
20868224
50.

Blurred vision and eye pain in a middle-aged woman.

Chacko J, Brock W, Brown H, Luetmer P, Giannini C.

J Neuroophthalmol. 2010 Sep;30(3):284-7. doi: 10.1097/WNO.0b013e3181ecdc45. No abstract available.

PMID:
20818207

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