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Items: 1 to 50 of 535

1.

Mechanical Ventilation for ARDS During Extracorporeal Life Support: Research and Practice.

Abrams D, Schmidt M, Pham T, Beitler JR, Fan E, Goligher EC, McNamee JJ, Patroniti N, Wilcox ME, Combes A, Ferguson ND, McAuley DF, Pesenti A, Quintel M, Fraser J, Hodgson CL, Hough CL, Mercat A, Mueller T, Pellegrino V, Ranieri VM, Rowan K, Shekar K, Brochard L, Brodie D; International ECMO Network (ECMONet).

Am J Respir Crit Care Med. 2019 Nov 14. doi: 10.1164/rccm.201907-1283CI. [Epub ahead of print]

PMID:
31726013
2.

A novel non-invasive method to detect excessively high respiratory effort and dynamic transpulmonary driving pressure during mechanical ventilation.

Bertoni M, Telias I, Urner M, Long M, Del Sorbo L, Fan E, Sinderby C, Beck J, Liu L, Qiu H, Wong J, Slutsky AS, Ferguson ND, Brochard LJ, Goligher EC.

Crit Care. 2019 Nov 6;23(1):346. doi: 10.1186/s13054-019-2617-0.

3.

Spontaneous Breathing Trials and Successful Extubation.

Mancebo J, Goligher E, Brochard L.

JAMA. 2019 Nov 5;322(17):1716-1717. doi: 10.1001/jama.2019.14226. No abstract available.

PMID:
31688879
4.

The importance of timing for the spontaneous breathing trial.

Perren A, Brochard L.

Ann Transl Med. 2019 Sep;7(Suppl 6):S210. doi: 10.21037/atm.2019.08.102. No abstract available.

5.

Effects of high-flow nasal cannula and non-invasive ventilation on inspiratory effort in hypercapnic patients with chronic obstructive pulmonary disease: a preliminary study.

Rittayamai N, Phuangchoei P, Tscheikuna J, Praphruetkit N, Brochard L.

Ann Intensive Care. 2019 Oct 22;9(1):122. doi: 10.1186/s13613-019-0597-5.

6.

Potential for Lung Recruitment Estimated by the Recruitment-to-Inflation Ratio in Acute Respiratory Distress Syndrome.

Chen L, Del Sorbo L, Grieco DL, Junhasavasdikul D, Rittayamai N, Soliman I, Sklar MC, Rauseo M, Ferguson ND, Fan E, Richard JM, Brochard L.

Am J Respir Crit Care Med. 2019 Oct 2. doi: 10.1164/rccm.201902-0334OC. [Epub ahead of print]

PMID:
31577153
7.

Effects of levosimendan on respiratory muscle function in patients weaning from mechanical ventilation.

Roesthuis L, van der Hoeven H, Sinderby C, Frenzel T, Ottenheijm C, Brochard L, Doorduin J, Heunks L.

Intensive Care Med. 2019 Oct;45(10):1372-1381. doi: 10.1007/s00134-019-05767-y. Epub 2019 Oct 1.

8.

Maximal Lung Recruitment in ARDS: A Nail in the Coffin.

Mancebo J, Mercat A, Brochard L.

Am J Respir Crit Care Med. 2019 Sep 18. doi: 10.1164/rccm.201908-1615ED. [Epub ahead of print] No abstract available.

PMID:
31532227
9.

Reply to: Simple Electrical Impedance Tomography Measures for the Assessment of Ventilation Distribution.

Brochard L, Yoshida T, Amato M.

Am J Respir Crit Care Med. 2019 Sep 17. doi: 10.1164/rccm.201908-1645LE. [Epub ahead of print] No abstract available.

PMID:
31526321
10.

Comparison of ventilatory modes to facilitate liberation from mechanical ventilation: protocol for a systematic review and network meta-analysis.

Lewis KA, Chaudhuri D, Guyatt G, Burns KEA, Bosma K, Ge L, Karachi T, Piraino T, Fernando SM, Ranganath N, Brochard L, Rochwerg B.

BMJ Open. 2019 Sep 5;9(9):e030407. doi: 10.1136/bmjopen-2019-030407.

11.

Respiratory Drive in Critically Ill Patients: Pathophysiology and Clinical Implications.

Vaporidi K, Akoumianaki E, Telias I, Goligher EC, Brochard L, Georgopoulos D.

Am J Respir Crit Care Med. 2019 Aug 22. doi: 10.1164/rccm.201903-0596SO. [Epub ahead of print]

PMID:
31437406
12.

In Memoriam: Brian Kavanagh, 1962 to 2019.

Orser BA, Brochard L.

Anesthesiology. 2019 Oct;131(4):759-761. doi: 10.1097/ALN.0000000000002944. No abstract available.

PMID:
31436547
13.

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome.

Yoshida T, Kavanagh BP, Brochard L.

N Engl J Med. 2019 Aug 22;381(8):786-787. doi: 10.1056/NEJMc1908874. No abstract available.

PMID:
31433933
14.

Information conveyed by electrical diaphragmatic activity during unstressed, stressed and assisted spontaneous breathing: a physiological study.

Piquilloud L, Beloncle F, Richard JM, Mancebo J, Mercat A, Brochard L.

Ann Intensive Care. 2019 Aug 14;9(1):89. doi: 10.1186/s13613-019-0564-1.

15.

Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study.

McNicholas BA, Madotto F, Pham T, Rezoagli E, Masterson CH, Horie S, Bellani G, Brochard L, Laffey JG; LUNG SAFE Investigators and the ESICM Trials Group.

Eur Respir J. 2019 Oct 17;54(4). pii: 1900609. doi: 10.1183/13993003.00609-2019. Print 2019 Oct.

PMID:
31346004
16.

Expiratory muscle dysfunction in critically ill patients: towards improved understanding.

Shi ZH, Jonkman A, de Vries H, Jansen D, Ottenheijm C, Girbes A, Spoelstra-de Man A, Zhou JX, Brochard L, Heunks L.

Intensive Care Med. 2019 Aug;45(8):1061-1071. doi: 10.1007/s00134-019-05664-4. Epub 2019 Jun 24. Review.

17.

Regional Ventilation Displayed by Electrical Impedance Tomography as an Incentive to Decrease Positive End-Expiratory Pressure.

Yoshida T, Piraino T, Lima CAS, Kavanagh BP, Amato MBP, Brochard L.

Am J Respir Crit Care Med. 2019 Oct 1;200(7):933-937. doi: 10.1164/rccm.201904-0797LE. No abstract available.

PMID:
31225973
18.

Formal guidelines: management of acute respiratory distress syndrome.

Papazian L, Aubron C, Brochard L, Chiche JD, Combes A, Dreyfuss D, Forel JM, Guérin C, Jaber S, Mekontso-Dessap A, Mercat A, Richard JC, Roux D, Vieillard-Baron A, Faure H.

Ann Intensive Care. 2019 Jun 13;9(1):69. doi: 10.1186/s13613-019-0540-9. Review.

19.

Reply to Schwarz et al.: Pathological Sleep and Wakefulness in the ICU and Weaning Failure: A Causal Relationship?

Dres M, Younes M, Brochard L.

Am J Respir Crit Care Med. 2019 Sep 1;200(5):648-649. doi: 10.1164/rccm.201905-0991LE. No abstract available.

20.

The Control of Breathing During Mechanical Ventilation.

Younes M, Brochard L.

Clin Chest Med. 2019 Jun;40(2):259-267. doi: 10.1016/j.ccm.2019.02.009. Review.

PMID:
31078208
21.

Acute Respiratory Distress Syndrome: Respiratory Monitoring and Pulmonary Physiology.

Coudroy R, Chen L, Pham T, Piraino T, Telias I, Brochard L.

Semin Respir Crit Care Med. 2019 Feb;40(1):66-80. doi: 10.1055/s-0039-1685159. Epub 2019 May 6.

PMID:
31060089
22.

Frequency of Screening for Weaning From Mechanical Ventilation: Two Contemporaneous Proof-of-Principle Randomized Controlled Trials.

Burns KEA, Wong JTY, Dodek P, Cook DJ, Lamontagne F, Cohen A, Mehta S, Kho ME, Hebert PC, Aslanian P, Friedrich JO, Brochard L, Rizvi L, Hand L, Meade MO, Amaral AC, Seely AJ; Canadian Critical Care Trials Group.

Crit Care Med. 2019 Jun;47(6):817-825. doi: 10.1097/CCM.0000000000003722.

PMID:
30920411
23.

Exogenous surfactant prevents hyperoxia-induced lung injury in adult mice.

Bezerra FS, Ramos CO, Castro TF, Araújo NPDS, de Souza ABF, Bandeira ACB, Costa GP, Cartelle CT, Talvani A, Cangussú SD, Brochard L, Nagato AC.

Intensive Care Med Exp. 2019 Mar 27;7(1):19. doi: 10.1186/s40635-019-0233-6.

24.

High flow nasal cannula compared with conventional oxygen therapy for acute hypoxemic respiratory failure: a systematic review and meta-analysis.

Rochwerg B, Granton D, Wang DX, Helviz Y, Einav S, Frat JP, Mekontso-Dessap A, Schreiber A, Azoulay E, Mercat A, Demoule A, Lemiale V, Pesenti A, Riviello ED, Mauri T, Mancebo J, Brochard L, Burns K.

Intensive Care Med. 2019 May;45(5):563-572. doi: 10.1007/s00134-019-05590-5. Epub 2019 Mar 19. Review.

PMID:
30888444
25.

The worldwide assessment of separation of patients from ventilatory assistance (WEAN SAFE) ERS Clinical Research Collaboration.

Heunks L, Bellani G, Pham T, Brochard L, Laffey JG.

Eur Respir J. 2019 Mar 18;53(3). pii: 1802228. doi: 10.1183/13993003.02228-2018. Print 2019 Mar. No abstract available.

PMID:
30886021
26.

Sleep and Pathological Wakefulness at the Time of Liberation from Mechanical Ventilation (SLEEWE). A Prospective Multicenter Physiological Study.

Dres M, Younes M, Rittayamai N, Kendzerska T, Telias I, Grieco DL, Pham T, Junhasavasdikul D, Chau E, Mehta S, Wilcox ME, Leung R, Drouot X, Brochard L.

Am J Respir Crit Care Med. 2019 May 1;199(9):1106-1115. doi: 10.1164/rccm.201811-2119OC.

PMID:
30818966
27.

Reply to Rezoagli et al.: CO2 Oscillation during Cardiopulmonary Resuscitation: The Role of Respiratory System Compliance.

Grieco DL, Brochard L, Richard JM.

Am J Respir Crit Care Med. 2019 May 15;199(10):1291-1293. doi: 10.1164/rccm.201901-0044LE. No abstract available.

28.

Inflammatory Cellular Response to Mechanical Ventilation in Elastase-Induced Experimental Emphysema: Role of Preexisting Alveolar Macrophages Infiltration.

Rouze A, Voiriot G, Guivarch E, Roux F, Tran Van Nhieu J, Isabey D, Brochard L, Maitre B, Mekontso-Dessap A, Boczkowski J.

Biomed Res Int. 2018 Dec 19;2018:5721293. doi: 10.1155/2018/5721293. eCollection 2018.

29.

ECMO for ARDS: from salvage to standard of care?

Abrams D, Ferguson ND, Brochard L, Fan E, Mercat A, Combes A, Pellegrino V, Schmidt M, Slutsky AS, Brodie D.

Lancet Respir Med. 2019 Feb;7(2):108-110. doi: 10.1016/S2213-2600(18)30506-X. Epub 2019 Jan 11. No abstract available. Erratum in: Lancet Respir Med. 2019 Feb;7(2):e9.

PMID:
30642778
30.

Beyond the guidelines for non-invasive ventilation in acute respiratory failure: implications for practice.

Bourke SC, Piraino T, Pisani L, Brochard L, Elliott MW.

Lancet Respir Med. 2018 Dec;6(12):935-947. doi: 10.1016/S2213-2600(18)30388-6. Review.

PMID:
30629932
31.

Reply to Chalkias and Xanthos: Airway Pressure Monitoring May Improve Small Airway Flow, Hemodynamics, and Tissue Oxygenation.

Grieco DL, Brochard L, Richard JM.

Am J Respir Crit Care Med. 2019 Apr 1;199(7):929-930. doi: 10.1164/rccm.201811-2234LE. No abstract available.

32.

Mechanism of airway closure in acute respiratory distress syndrome: a possible role of surfactant depletion.

Coudroy R, Lu C, Chen L, Demoule A, Brochard L.

Intensive Care Med. 2019 Feb;45(2):290-291. doi: 10.1007/s00134-018-5501-5. Epub 2018 Dec 17. No abstract available.

PMID:
30560279
33.

Guiding ventilation with transpulmonary pressure.

Yoshida T, Grieco DL, Brochard L.

Intensive Care Med. 2019 Apr;45(4):535-538. doi: 10.1007/s00134-018-5483-3. Epub 2018 Nov 30. No abstract available.

PMID:
30506355
34.

Editorial: Every breath you take…should be monitored.

Pham T, Brochard LJ.

Curr Opin Crit Care. 2019 Feb;25(1):1-2. doi: 10.1097/MCC.0000000000000576. No abstract available.

PMID:
30516589
35.

Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study.

Pham T, Serpa Neto A, Pelosi P, Laffey JG, De Haro C, Lorente JA, Bellani G, Fan E, Brochard LJ, Pesenti A, Schultz MJ, Artigas A; LUNG SAFE Investigators* and the European Society of Intensive Care Medicine Trials Group.

Anesthesiology. 2019 Feb;130(2):263-283. doi: 10.1097/ALN.0000000000002508.

PMID:
30499850
36.

Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future.

Boyle AJ, Sklar MC, McNamee JJ, Brodie D, Slutsky AS, Brochard L, McAuley DF; International ECMO Network (ECMONet).

Lancet Respir Med. 2018 Nov;6(11):874-884. doi: 10.1016/S2213-2600(18)30326-6. Review.

PMID:
30484429
37.

Diaphragmatic myotrauma: a mediator of prolonged ventilation and poor patient outcomes in acute respiratory failure.

Goligher EC, Brochard LJ, Reid WD, Fan E, Saarela O, Slutsky AS, Kavanagh BP, Rubenfeld GD, Ferguson ND.

Lancet Respir Med. 2019 Jan;7(1):90-98. doi: 10.1016/S2213-2600(18)30366-7. Epub 2018 Nov 16. Review.

PMID:
30455078
38.

Mechanical Power: A Biomarker for the Lung?

Brochard L, Bersten A.

Anesthesiology. 2019 Jan;130(1):9-11. doi: 10.1097/ALN.0000000000002505. No abstract available.

PMID:
30383544
39.

Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study.

van Haren F, Pham T, Brochard L, Bellani G, Laffey J, Dres M, Fan E, Goligher EC, Heunks L, Lynch J, Wrigge H, McAuley D; Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) Investigators.

Crit Care Med. 2019 Feb;47(2):229-238. doi: 10.1097/CCM.0000000000003519.

40.

Obstructive sleep apnea in patients surviving acute hypercapnic respiratory failure is best predicted by static hyperinflation.

Adler D, Dupuis-Lozeron E, Janssens JP, Soccal PM, Lador F, Brochard L, Pépin JL.

PLoS One. 2018 Oct 25;13(10):e0205669. doi: 10.1371/journal.pone.0205669. eCollection 2018.

41.

Reply to Koutsoukou: Expiratory Flow Limitation and Airway Closure in Patients with Acute Respiratory Distress Syndrome.

Chen L, Del Sorbo L, Fan E, Brochard L.

Am J Respir Crit Care Med. 2019 Jan 1;199(1):128-129. doi: 10.1164/rccm.201808-1504LE. No abstract available.

PMID:
30256655
42.

High-flow nasal oxygen versus noninvasive ventilation in adult patients with cystic fibrosis: a randomized crossover physiological study.

Sklar MC, Dres M, Rittayamai N, West B, Grieco DL, Telias I, Junhasavasdikul D, Rauseo M, Pham T, Madotto F, Campbell C, Tullis E, Brochard L.

Ann Intensive Care. 2018 Sep 5;8(1):85. doi: 10.1186/s13613-018-0432-4.

43.

Flexibility of nanolayers and stacks: implications in the nanostructuration of clays.

Honorio T, Brochard L, Vandamme M, Lebée A.

Soft Matter. 2018 Sep 19;14(36):7354-7367. doi: 10.1039/c8sm01359d.

PMID:
30187051
44.

Declaration of conflicts of interest: a 'crooked' line towards scientific integrity.

Brochard L, Kavanagh BP.

Intensive Care Med. 2018 Oct;44(10):1732-1734. doi: 10.1007/s00134-018-5358-7. Epub 2018 Sep 3. No abstract available.

PMID:
30178137
45.

Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: study protocol for a pilot randomized controlled trial, the PROTECTION trial.

Mauri T, Foti G, Fornari C, Constantin JM, Guerin C, Pelosi P, Ranieri M, Conti S, Tubiolo D, Rondelli E, Lovisari F, Fossali T, Spadaro S, Grieco DL, Navalesi P, Calamai I, Becher T, Roca O, Wang YM, Knafelj R, Cortegiani A, Mancebo J, Brochard L, Pesenti A; Protection Study Group.

Trials. 2018 Aug 29;19(1):460. doi: 10.1186/s13063-018-2828-8.

46.

Asynchrony Consequences and Management.

Pham T, Telias I, Piraino T, Yoshida T, Brochard LJ.

Crit Care Clin. 2018 Jul;34(3):325-341. doi: 10.1016/j.ccc.2018.03.008. Review.

PMID:
29907268
47.

Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome.

Combes A, Hajage D, Capellier G, Demoule A, Lavoué S, Guervilly C, Da Silva D, Zafrani L, Tirot P, Veber B, Maury E, Levy B, Cohen Y, Richard C, Kalfon P, Bouadma L, Mehdaoui H, Beduneau G, Lebreton G, Brochard L, Ferguson ND, Fan E, Slutsky AS, Brodie D, Mercat A; EOLIA Trial Group, REVA, and ECMONet.

N Engl J Med. 2018 May 24;378(21):1965-1975. doi: 10.1056/NEJMoa1800385.

48.

How Ventilation Is Delivered During Cardiopulmonary Resuscitation: An International Survey.

Cordioli RL, Brochard L, Suppan L, Lyazidi A, Templier F, Khoury A, Delisle S, Savary D, Richard JC.

Respir Care. 2018 Oct;63(10):1293-1301. doi: 10.4187/respcare.05964. Epub 2018 May 8.

49.

Continuous Negative Abdominal Pressure Reduces Ventilator-induced Lung Injury in a Porcine Model.

Yoshida T, Engelberts D, Otulakowski G, Katira B, Post M, Ferguson ND, Brochard L, Amato MBP, Kavanagh BP.

Anesthesiology. 2018 Jul;129(1):163-172. doi: 10.1097/ALN.0000000000002236.

PMID:
29708892
50.

Lung Ultrasound and Microbubbles Enhance Aminoglycoside Efficacy and Delivery to the Lung in Escherichia coli-induced Pneumonia and Acute Respiratory Distress Syndrome.

Sugiyama MG, Mintsopoulos V, Raheel H, Goldenberg NM, Batt JE, Brochard L, Kuebler WM, Leong-Poi H, Karshafian R, Lee WL.

Am J Respir Crit Care Med. 2018 Aug 1;198(3):404-408. doi: 10.1164/rccm.201711-2259LE. No abstract available.

PMID:
29638143

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