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Items: 1 to 50 of 87

1.

Familial deep cavitating state with a glutathione metabolism defect.

Rendu J, Van Noolen L, Garrel C, Brocard J, Marty I, Corne C, Fauré J, Besson G.

Ann Clin Transl Neurol. 2019 Nov 9. doi: 10.1002/acn3.50933. [Epub ahead of print]

2.

Interplay between Triadin and Calsequestrin in the Pathogenesis of CPVT in the Mouse.

Cacheux M, Fauconnier J, Thireau J, Osseni A, Brocard J, Roux-Buisson N, Brocard J, Fauré J, Lacampagne A, Marty I.

Mol Ther. 2019 Sep 13. pii: S1525-0016(19)30415-0. doi: 10.1016/j.ymthe.2019.09.012. [Epub ahead of print]

PMID:
31607542
3.

'Dusty core disease' (DuCD): expanding morphological spectrum of RYR1 recessive myopathies.

Garibaldi M, Rendu J, Brocard J, Lacene E, Fauré J, Brochier G, Beuvin M, Labasse C, Madelaine A, Malfatti E, Bevilacqua JA, Lubieniecki F, Monges S, Taratuto AL, Laporte J, Marty I, Antonini G, Romero NB.

Acta Neuropathol Commun. 2019 Jan 5;7(1):3. doi: 10.1186/s40478-018-0655-5.

4.

Deletion of the microtubule-associated protein 6 (MAP6) results in skeletal muscle dysfunction.

Sébastien M, Giannesini B, Aubin P, Brocard J, Chivet M, Pietrangelo L, Boncompagni S, Bosc C, Brocard J, Rendu J, Gory-Fauré S, Andrieux A, Fourest-Lieuvin A, Fauré J, Marty I.

Skelet Muscle. 2018 Sep 19;8(1):30. doi: 10.1186/s13395-018-0176-8.

5.

A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines.

Peris L, Bisbal M, Martinez-Hernandez J, Saoudi Y, Jonckheere J, Rolland M, Sebastien M, Brocard J, Denarier E, Bosc C, Guerin C, Gory-Fauré S, Deloulme JC, Lanté F, Arnal I, Buisson A, Goldberg Y, Blanchoin L, Delphin C, Andrieux A.

Nat Commun. 2018 Sep 17;9(1):3775. doi: 10.1038/s41467-018-05869-z.

6.

Short- and long-term efficacy of electroconvulsive stimulation in animal models of depression: The essential role of neuronal survival.

Jonckheere J, Deloulme JC, Dall'Igna G, Chauliac N, Pelluet A, Nguon AS, Lentini C, Brocard J, Denarier E, Brugière S, Couté Y, Heinrich C, Porcher C, Holtzmann J, Andrieux A, Suaud-Chagny MF, Gory-Fauré S.

Brain Stimul. 2018 Nov - Dec;11(6):1336-1347. doi: 10.1016/j.brs.2018.08.001. Epub 2018 Aug 15.

7.

MAP6 interacts with Tctex1 and Cav 2.2/N-type calcium channels to regulate calcium signalling in neurons.

Brocard J, Dufour F, Gory-Fauré S, Arnoult C, Bosc C, Denarier E, Peris L, Saoudi Y, De Waard M, Andrieux A.

Eur J Neurosci. 2017 Dec;46(11):2754-2767. doi: 10.1111/ejn.13766. Epub 2017 Nov 22.

8.

3D imaging of the brain morphology and connectivity defects in a model of psychiatric disorders: MAP6-KO mice.

Gimenez U, Boulan B, Mauconduit F, Taurel F, Leclercq M, Denarier E, Brocard J, Gory-Fauré S, Andrieux A, Lahrech H, Deloulme JC.

Sci Rep. 2017 Sep 4;7(1):10308. doi: 10.1038/s41598-017-10544-2.

9.

Functional Characterization of a Central Core Disease RyR1 Mutation (p.Y4864H) Associated with Quantitative Defect in RyR1 Protein.

Cacheux M, Blum A, Sébastien M, Wozny AS, Brocard J, Mamchaoui K, Mouly V, Roux-Buisson N, Rendu J, Monnier N, Krivosic R, Allen P, Lacour A, Lunardi J, Fauré J, Marty I.

J Neuromuscul Dis. 2015 Nov 20;2(4):421-432.

10.

Functional Characterization and Rescue of a Deep Intronic Mutation in OCRL Gene Responsible for Lowe Syndrome.

Rendu J, Montjean R, Coutton C, Suri M, Chicanne G, Petiot A, Brocard J, Grunwald D, Pietri Rouxel F, Payrastre B, Lunardi J, Dorseuil O, Marty I, Fauré J.

Hum Mutat. 2017 Feb;38(2):152-159. doi: 10.1002/humu.23139. Epub 2016 Nov 21.

PMID:
27790796
11.

Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth.

Deloulme JC, Gory-Fauré S, Mauconduit F, Chauvet S, Jonckheere J, Boulan B, Mire E, Xue J, Jany M, Maucler C, Deparis AA, Montigon O, Daoust A, Barbier EL, Bosc C, Deglon N, Brocard J, Denarier E, Le Brun I, Pernet-Gallay K, Vilgrain I, Robinson PJ, Lahrech H, Mann F, Andrieux A.

Nat Commun. 2015 Jun 3;6:7246. doi: 10.1038/ncomms8246.

12.

Non-microtubular localizations of microtubule-associated protein 6 (MAP6).

Gory-Fauré S, Windscheid V, Brocard J, Montessuit S, Tsutsumi R, Denarier E, Fukata Y, Bosc C, Delaroche J, Collomb N, Fukata M, Martinou JC, Pernet-Gallay K, Andrieux A.

PLoS One. 2014 Dec 19;9(12):e114905. doi: 10.1371/journal.pone.0114905. eCollection 2014.

13.

Nanoscale surface topography reshapes neuronal growth in culture.

Bugnicourt G, Brocard J, Nicolas A, Villard C.

Langmuir. 2014 Apr 22;30(15):4441-9. doi: 10.1021/la5001683. Epub 2014 Apr 8.

14.

Impact of manganese on primary hippocampal neurons from rodents.

Daoust A, Saoudi Y, Brocard J, Collomb N, Batandier C, Bisbal M, Salomé M, Andrieux A, Bohic S, Barbier EL.

Hippocampus. 2014 May;24(5):598-610. doi: 10.1002/hipo.22252. Epub 2014 Mar 3.

PMID:
24500839
15.

An integrated diagnosis strategy for congenital myopathies.

Böhm J, Vasli N, Malfatti E, Le Gras S, Feger C, Jost B, Monnier N, Brocard J, Karasoy H, Gérard M, Walter MC, Reilich P, Biancalana V, Kretz C, Messaddeq N, Marty I, Lunardi J, Romero NB, Laporte J.

PLoS One. 2013 Jun 24;8(6):e67527. doi: 10.1371/journal.pone.0067527. Print 2013.

16.

Exon skipping as a therapeutic strategy applied to an RYR1 mutation with pseudo-exon inclusion causing a severe core myopathy.

Rendu J, Brocard J, Denarier E, Monnier N, Piétri-Rouxel F, Beley C, Roux-Buisson N, Gilbert-Dussardier B, Perez MJ, Romero N, Garcia L, Lunardi J, Fauré J, Fourest-Lieuvin A, Marty I.

Hum Gene Ther. 2013 Jul;24(7):702-13. doi: 10.1089/hum.2013.052.

17.

The transcriptomic response of mixed neuron-glial cell cultures to 1,25-dihydroxyvitamin d3 includes genes limiting the progression of neurodegenerative diseases.

Nissou MF, Brocard J, El Atifi M, Guttin A, Andrieux A, Berger F, Issartel JP, Wion D.

J Alzheimers Dis. 2013;35(3):553-64. doi: 10.3233/JAD-122005.

18.

Ataxia with cerebellar lesions in mice expressing chimeric PrP-Dpl protein.

Lemaire-Vieille C, Bailly Y, Erlich P, Loeuillet C, Brocard J, Haeberlé AM, Bombarde G, Rak C, Demais V, Dumestre-Pérard C, Gagnon J, Cesbron JY.

J Neurosci. 2013 Jan 23;33(4):1391-9. doi: 10.1523/JNEUROSCI.2231-12.2013.

19.

Reduced expression of STOP/MAP6 in mice leads to cognitive deficits.

Volle J, Brocard J, Saoud M, Gory-Faure S, Brunelin J, Andrieux A, Suaud-Chagny MF.

Schizophr Bull. 2013 Sep;39(5):969-78. doi: 10.1093/schbul/sbs113. Epub 2012 Sep 20.

20.

Role of triadin in the organization of reticulum membrane at the muscle triad.

Fourest-Lieuvin A, Rendu J, Osseni A, Pernet-Gallay K, Rossi D, Oddoux S, Brocard J, Sorrentino V, Marty I, Fauré J.

J Cell Sci. 2012 Jul 15;125(Pt 14):3443-53. doi: 10.1242/jcs.100958. Epub 2012 Apr 14.

21.

How morphological constraints affect axonal polarity in mouse neurons.

Roth S, Bisbal M, Brocard J, Bugnicourt G, Saoudi Y, Andrieux A, Gory-Fauré S, Villard C.

PLoS One. 2012;7(3):e33623. doi: 10.1371/journal.pone.0033623. Epub 2012 Mar 21.

22.

Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human.

Roux-Buisson N, Cacheux M, Fourest-Lieuvin A, Fauconnier J, Brocard J, Denjoy I, Durand P, Guicheney P, Kyndt F, Leenhardt A, Le Marec H, Lucet V, Mabo P, Probst V, Monnier N, Ray PF, Santoni E, Trémeaux P, Lacampagne A, Fauré J, Lunardi J, Marty I.

Hum Mol Genet. 2012 Jun 15;21(12):2759-67. doi: 10.1093/hmg/dds104. Epub 2012 Mar 14.

23.

Neuronal architectures with axo-dendritic polarity above silicon nanowires.

Roth S, Bugnicourt G, Bisbal M, Gory-Fauré S, Brocard J, Villard C.

Small. 2012 Mar 12;8(5):671-5. doi: 10.1002/smll.201102325. Epub 2012 Jan 9.

PMID:
22228548
24.

Mutation of Ser172 in yeast β tubulin induces defects in microtubule dynamics and cell division.

Caudron F, Denarier E, Thibout-Quintana JC, Brocard J, Andrieux A, Fourest-Lieuvin A.

PLoS One. 2010 Oct 21;5(10):e13553. doi: 10.1371/journal.pone.0013553.

25.

Caveolin 3 is associated with the calcium release complex and is modified via in vivo triadin modification.

Vassilopoulos S, Oddoux S, Groh S, Cacheux M, Fauré J, Brocard J, Campbell KP, Marty I.

Biochemistry. 2010 Jul 27;49(29):6130-5. doi: 10.1021/bi100796v.

26.

Trioxaferroquines as new hybrid antimalarial drugs.

Bellot F, Coslédan F, Vendier L, Brocard J, Meunier B, Robert A.

J Med Chem. 2010 May 27;53(10):4103-9. doi: 10.1021/jm100117e.

PMID:
20443628
27.

Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice.

Delotterie D, Ruiz G, Brocard J, Schweitzer A, Roucard C, Roche Y, Suaud-Chagny MF, Bressand K, Andrieux A.

Psychopharmacology (Berl). 2010 Jan;208(1):131-41. doi: 10.1007/s00213-009-1712-3. Epub 2009 Nov 21.

28.

Triadin deletion induces impaired skeletal muscle function.

Oddoux S, Brocard J, Schweitzer A, Szentesi P, Giannesini B, Brocard J, Fauré J, Pernet-Gallay K, Bendahan D, Lunardi J, Csernoch L, Marty I.

J Biol Chem. 2009 Dec 11;284(50):34918-29. doi: 10.1074/jbc.M109.022442. Epub 2009 Oct 19.

29.

Motor-dependent microtubule disassembly driven by tubulin tyrosination.

Peris L, Wagenbach M, Lafanechère L, Brocard J, Moore AT, Kozielski F, Job D, Wordeman L, Andrieux A.

J Cell Biol. 2009 Jun 29;185(7):1159-66. doi: 10.1083/jcb.200902142.

30.

Triadin: what possible function 20 years later?

Marty I, Fauré J, Fourest-Lieuvin A, Vassilopoulos S, Oddoux S, Brocard J.

J Physiol. 2009 Jul 1;587(Pt 13):3117-21. doi: 10.1113/jphysiol.2009.171892. Epub 2009 Apr 29. Review.

31.

Ferroquine, an ingenious antimalarial drug: thoughts on the mechanism of action.

Dubar F, Khalife J, Brocard J, Dive D, Biot C.

Molecules. 2008 Nov 20;13(11):2900-7. doi: 10.3390/molecules13112900.

32.

Bioluminescent imaging of Ca2+ activity reveals spatiotemporal dynamics in glial networks of dark-adapted mouse retina.

Agulhon C, Platel JC, Kolomiets B, Forster V, Picaud S, Brocard J, Faure P, Brulet P.

J Physiol. 2007 Sep 15;583(Pt 3):945-58. Epub 2007 Jul 12.

33.

Synchrony of spontaneous calcium activity in mouse neocortex before synaptogenesis.

Platel JC, Dupuis A, Boisseau S, Villaz M, Albrieux M, Brocard J.

Eur J Neurosci. 2007 Feb;25(4):920-8.

PMID:
17331190
34.

Retrograde regulation of store-operated calcium channels by the ryanodine receptor-associated protein triadin 95 in rat skeletal myotubes.

Vassilopoulos S, Brocard J, Garcia L, Marty I, Bouron A.

Cell Calcium. 2007 Feb;41(2):179-85. Epub 2006 Aug 4.

PMID:
16889828
35.

Probing the role of the covalent linkage of ferrocene into a chloroquine template.

Biot C, Daher W, Ndiaye CM, Melnyk P, Pradines B, Chavain N, Pellet A, Fraisse L, Pelinski L, Jarry C, Brocard J, Khalife J, Forfar-Bares I, Dive D.

J Med Chem. 2006 Jul 27;49(15):4707-14.

PMID:
16854077
36.

Phosphorylation of microtubule-associated protein STOP by calmodulin kinase II.

Baratier J, Peris L, Brocard J, Gory-Fauré S, Dufour F, Bosc C, Fourest-Lieuvin A, Blanchoin L, Salin P, Job D, Andrieux A.

J Biol Chem. 2006 Jul 14;281(28):19561-9. Epub 2006 May 1.

37.

[Neuronal activity before synaptogenesis: Na+ channels, Ca2+ signalling and glutamatergic secretion or how to play the part when some famous actors are missing in the scene?].

Albrieux M, Platel JC, Dupuis A, Brocard J, Savasta M, Villaz M.

Med Sci (Paris). 2006 Apr;22(4):359-61. French. No abstract available.

38.

Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure.

Daher W, Biot C, Fandeur T, Jouin H, Pelinski L, Viscogliosi E, Fraisse L, Pradines B, Brocard J, Khalife J, Dive D.

Malar J. 2006 Feb 7;5:11.

39.

In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum.

Daher W, Pelinski L, Klieber S, Sadoun F, Meunier V, Bourrié M, Biot C, Guillou F, Fabre G, Brocard J, Fraisse L, Maffrand JP, Khalife J, Dive D.

Drug Metab Dispos. 2006 Apr;34(4):667-82. Epub 2006 Jan 13.

PMID:
16415117
40.

Na+ channel-mediated Ca2+ entry leads to glutamate secretion in mouse neocortical preplate.

Platel JC, Boisseau S, Dupuis A, Brocard J, Poupard A, Savasta M, Villaz M, Albrieux M.

Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19174-9. Epub 2005 Dec 15.

41.

Synthesis and in vitro activities of ferrocenic aminohydroxynaphthoquinones against Toxoplasma gondii and Plasmodium falciparum.

Baramee A, Coppin A, Mortuaire M, Pelinski L, Tomavo S, Brocard J.

Bioorg Med Chem. 2006 Mar 1;14(5):1294-302. Epub 2005 Oct 18.

PMID:
16242338
42.

Triadin (Trisk 95) overexpression blocks excitation-contraction coupling in rat skeletal myotubes.

Rezgui SS, Vassilopoulos S, Brocard J, Platel JC, Bouron A, Arnoult C, Oddoux S, Garcia L, De Waard M, Marty I.

J Biol Chem. 2005 Nov 25;280(47):39302-8. Epub 2005 Sep 21.

43.

Analysis of immune response patterns in naïve and Plasmodium berghei-infected young rats following a ferroquine treatment.

Pierrot C, Lafitte S, Dive D, Fraisse L, Brocard J, Khalife J.

Int J Parasitol. 2005 Dec;35(14):1601-10. Epub 2005 Aug 24.

PMID:
16140302
44.

Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.

Biot C, Taramelli D, Forfar-Bares I, Maciejewski LA, Boyce M, Nowogrocki G, Brocard JS, Basilico N, Olliaro P, Egan TJ.

Mol Pharm. 2005 May-Jun;2(3):185-93.

PMID:
15934779
45.

Triadins are not triad-specific proteins: two new skeletal muscle triadins possibly involved in the architecture of sarcoplasmic reticulum.

Vassilopoulos S, Thevenon D, Rezgui SS, Brocard J, Chapel A, Lacampagne A, Lunardi J, Dewaard M, Marty I.

J Biol Chem. 2005 Aug 5;280(31):28601-9. Epub 2005 May 31.

46.

Synthesis and antimycobacterial activity of ferrocenyl ethambutol analogues and ferrocenyl diamines.

Razafimahefa D, Ralambomanana DA, Hammouche L, Pélinski L, Lauvagie S, Bebear C, Brocard J, Maugein J.

Bioorg Med Chem Lett. 2005 May 2;15(9):2301-3.

PMID:
15837313
47.

Synthesis and chloroquine-enhancing activity of Na-deacetyl-ferrocenoyl-strychnobrasiline.

Razafimahefa D, Pélinski L, Martin MT, Ramanitrahasimbola D, Rasoanaivo P, Brocard J.

Bioorg Med Chem Lett. 2005 Feb 15;15(4):1239-41.

PMID:
15686950
48.

Inhibition of voltage-gated calcium channels by sequestration of beta subunits.

Cuchillo-Ibañez I, Aldea M, Brocard J, Albillos A, Weiss N, Garcia AG, De Waard M.

Biochem Biophys Res Commun. 2003 Nov 28;311(4):1000-7.

PMID:
14623281
49.

Glutamate decreases mitochondrial size and movement in primary forebrain neurons.

Rintoul GL, Filiano AJ, Brocard JB, Kress GJ, Reynolds IJ.

J Neurosci. 2003 Aug 27;23(21):7881-8.

50.

New perspectives on mitochondrial morphology in cell function.

Brocard JB, Rintoul GL, Reynolds IJ.

Biol Cell. 2003 Jul;95(5):239-42. Review.

PMID:
12941521

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