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Items: 22


Strengthening Health Systems While Responding to a Health Crisis: Lessons Learned by a Nongovernmental Organization During the Ebola Virus Disease Epidemic in Sierra Leone.

Cancedda C, Davis SM, Dierberg KL, Lascher J, Kelly JD, Barrie MB, Koroma AP, George P, Kamara AA, Marsh R, Sumbuya MS, Nutt CT, Scott KW, Thomas E, Bollbach K, Sesay A, Barrie A, Barrera E, Barron K, Welch J, Bhadelia N, Frankfurter RG, Dahl OM, Das S, Rollins RE, Eustis B, Schwartz A, Pertile P, Pavlopoulos I, Mayfield A, Marsh RH, Dibba Y, Kloepper D, Hall A, Huster K, Grady M, Spray K, Walton DA, Daboh F, Nally C, James S, Warren GS, Chang J, Drasher M, Lamin G, Bangura S, Miller AC, Michaelis AP, McBain R, Broadhurst MJ, Murray M, Richardson ET, Philip T, Gottlieb GL, Mukherjee JS, Farmer PE.

J Infect Dis. 2016 Oct 15;214(suppl 3):S153-S163. Epub 2016 Sep 28.


Diagnosis of Ebola Virus Disease: Past, Present, and Future.

Broadhurst MJ, Brooks TJ, Pollock NR.

Clin Microbiol Rev. 2016 Oct;29(4):773-93. doi: 10.1128/CMR.00003-16. Review.


Performance of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone: A Field Evaluation Study.

Semper AE, Broadhurst MJ, Richards J, Foster GM, Simpson AJ, Logue CH, Kelly JD, Miller A, Brooks TJ, Murray M, Pollock NR.

PLoS Med. 2016 Mar 29;13(3):e1001980. doi: 10.1371/journal.pmed.1001980. eCollection 2016 Mar.


ReEBOV Antigen Rapid Test kit for Ebola - Authors' reply.

Broadhurst MJ, Semper A, Bailey D, Pollock NR.

Lancet. 2015 Dec 5;386(10010):2255-6. doi: 10.1016/S0140-6736(15)01109-5. No abstract available.


ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study.

Broadhurst MJ, Kelly JD, Miller A, Semper A, Bailey D, Groppelli E, Simpson A, Brooks T, Hula S, Nyoni W, Sankoh AB, Kanu S, Jalloh A, Ton Q, Sarchet N, George P, Perkins MD, Wonderly B, Murray M, Pollock NR.

Lancet. 2015 Aug 29;386(9996):867-74. doi: 10.1016/S0140-6736(15)61042-X. Epub 2015 Jun 25.


Discordance between peripheral and colonic markers of inflammation during suppressive ART.

Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM.

J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):133-41. doi: 10.1097/01.qai.0000437172.08127.0b.


Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism.

Vujkovic-Cvijin I, Dunham RM, Iwai S, Maher MC, Albright RG, Broadhurst MJ, Hernandez RD, Lederman MM, Huang Y, Somsouk M, Deeks SG, Hunt PW, Lynch SV, McCune JM.

Sci Transl Med. 2013 Jul 10;5(193):193ra91. doi: 10.1126/scitranslmed.3006438. Erratum in: Sci Transl Med. 2017 Nov 8;9(415):.


Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.

Broadhurst MJ, Ardeshir A, Kanwar B, Mirpuri J, Gundra UM, Leung JM, Wiens KE, Vujkovic-Cvijin I, Kim CC, Yarovinsky F, Lerche NW, McCune JM, Loke P.

PLoS Pathog. 2012;8(11):e1003000. doi: 10.1371/journal.ppat.1003000. Epub 2012 Nov 15.


Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice.

Broadhurst MJ, Leung JM, Lim KC, Girgis NM, Gundra UM, Fallon PG, Premenko-Lanier M, McKerrow JH, McCune JM, Loke P.

PLoS Pathog. 2012;8(8):e1002883. doi: 10.1371/journal.ppat.1002883. Epub 2012 Aug 23.


Helminthic therapy: improving mucosal barrier function.

Wolff MJ, Broadhurst MJ, Loke P.

Trends Parasitol. 2012 May;28(5):187-94. doi: 10.1016/ Epub 2012 Mar 28. Review.


IL-22+ CD4+ T cells are associated with therapeutic trichuris trichiura infection in an ulcerative colitis patient.

Broadhurst MJ, Leung JM, Kashyap V, McCune JM, Mahadevan U, McKerrow JH, Loke P.

Sci Transl Med. 2010 Dec 1;2(60):60ra88. doi: 10.1126/scitranslmed.3001500.


Comparison of rocking edge spacing for two common designs of swivel walkers.

May CS, Broadhurst MJ, Major RE.

Prosthet Orthot Int. 2004 Apr;28(1):75-80.


Ro 32-3555, an orally active collagenase inhibitor, prevents cartilage breakdown in vitro and in vivo.

Lewis EJ, Bishop J, Bottomley KM, Bradshaw D, Brewster M, Broadhurst MJ, Brown PA, Budd JM, Elliott L, Greenham AK, Johnson WH, Nixon JS, Rose F, Sutton B, Wilson K.

Br J Pharmacol. 1997 Jun;121(3):540-6.


Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors.

Bottomley KM, Borkakoti N, Bradshaw D, Brown PA, Broadhurst MJ, Budd JM, Elliott L, Eyers P, Hallam TJ, Handa BK, Hill CH, James M, Lahm HW, Lawton G, Merritt JE, Nixon JS, Röthlisberger U, Whittle A, Johnson WH.

Biochem J. 1997 Apr 15;323 ( Pt 2):483-8.


Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor.

Borkakoti N, Winkler FK, Williams DH, D'Arcy A, Broadhurst MJ, Brown PA, Johnson WH, Murray EJ.

Nat Struct Biol. 1994 Feb;1(2):106-10.


Potent collagenase inhibitors prevent interleukin-1-induced cartilage degradation in vitro.

Nixon JS, Bottomley KM, Broadhurst MJ, Brown PA, Johnson WH, Lawton G, Marley J, Sedgwick AD, Wilkinson SE.

Int J Tissue React. 1991;13(5):237-41.


Synthesis and antitumor activity of 9-[(carbamoyloxy)alkyl]anthracyclines: a novel class of anthracycline derivatives.

Adams N, Blake C, Broadhurst MJ, Bushnell DJ, Hassall CH, Hartmann HR, Keech E, Stratton AR, Thomas GJ.

J Med Chem. 1990 Sep;33(9):2380-4.


Synthesis and antitumor activity of novel 4-demethoxyanthracyclines.

Adams N, Blake C, Broadhurst MJ, Bushnell DJ, Hassall CH, Hartmann HR, Keech E, Stratton AR, Thomas GJ.

J Med Chem. 1990 Sep;33(9):2375-9.


Mechanical feeding aids for patients with ataxia: design considerations.

Broadhurst MJ, Stammers CW.

J Biomed Eng. 1990 May;12(3):209-14.


1H-NMR and protection studies of interactions between ligands and bovine pancreatic phospholipase A2.

Williamson MP, Davis PD, Broadhurst MJ, Nixon JS.

Biochim Biophys Acta. 1989 Jul 27;997(1-2):9-14.


9-alkyl anthracyclines. Absence of cross-resistance to adriamycin in human and murine cell cultures.

Scott CA, Westmacott D, Broadhurst MJ, Thomas GJ, Hall MJ.

Br J Cancer. 1986 May;53(5):595-600.


The in vitro effects and cross-resistance patterns of some novel anthracyclines.

Twentyman PR, Fox NE, Wright KA, Workman P, Broadhurst MJ, Martin JA, Bleehen NM.

Br J Cancer. 1986 May;53(5):585-94.

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