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Items: 1 to 50 of 66

1.

Models for Understanding Resistance to Chemotherapy in Liver Cancer.

Marin JJG, Herraez E, Lozano E, Macias RIR, Briz O.

Cancers (Basel). 2019 Oct 29;11(11). pii: E1677. doi: 10.3390/cancers11111677. Review.

2.

Sensitizing gastric adenocarcinoma to chemotherapy by pharmacological manipulation of drug transporters.

Al-Abdulla R, Perez-Silva L, Lozano E, Macias RIR, Herraez E, Abad M, Segues N, Bujanda L, Briz O, Marin JJG.

Biochem Pharmacol. 2019 Oct 24;171:113682. doi: 10.1016/j.bcp.2019.113682. [Epub ahead of print]

PMID:
31669256
3.

What "The Cancer Genome Atlas" database tells us about the role of ATP-binding cassette (ABC) proteins in chemoresistance to anticancer drugs.

Briz O, Perez-Silva L, Al-Abdulla R, Abete L, Reviejo M, Romero MR, Marin JJG.

Expert Opin Drug Metab Toxicol. 2019 Jul;15(7):577-593. doi: 10.1080/17425255.2019.1631285. Epub 2019 Jun 23. Review.

PMID:
31185182
4.

Causes of hOCT1-Dependent Cholangiocarcinoma Resistance to Sorafenib and Sensitization by Tumor-Selective Gene Therapy.

Lozano E, Macias RIR, Monte MJ, Asensio M, Del Carmen S, Sanchez-Vicente L, Alonso-Peña M, Al-Abdulla R, Munoz-Garrido P, Satriano L, O'Rourke CJ, Banales JM, Avila MA, Martinez-Chantar ML, Andersen JB, Briz O, Marin JJG.

Hepatology. 2019 Oct;70(4):1246-1261. doi: 10.1002/hep.30656. Epub 2019 May 20.

PMID:
30972782
5.

Mechanisms of Anticancer Drug Resistance in Hepatoblastoma.

Marin JJG, Cives-Losada C, Asensio M, Lozano E, Briz O, Macias RIR.

Cancers (Basel). 2019 Mar 22;11(3). pii: E407. doi: 10.3390/cancers11030407. Review.

6.

Unraveling 'The Cancer Genome Atlas' information on the role of SLC transporters in anticancer drug uptake.

Al-Abdulla R, Perez-Silva L, Abete L, Romero MR, Briz O, Marin JJG.

Expert Rev Clin Pharmacol. 2019 Apr;12(4):329-341. doi: 10.1080/17512433.2019.1581605. Epub 2019 Feb 26. Review.

PMID:
30744443
7.

Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps.

Di Giacomo S, Briz O, Monte MJ, Sanchez-Vicente L, Abete L, Lozano E, Mazzanti G, Di Sotto A, Marin JJG.

Arch Toxicol. 2019 Mar;93(3):623-634. doi: 10.1007/s00204-019-02395-9. Epub 2019 Jan 18.

PMID:
30659321
8.

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib.

Al-Abdulla R, Lozano E, Macias RIR, Monte MJ, Briz O, O'Rourke CJ, Serrano MA, Banales JM, Avila MA, Martinez-Chantar ML, Geier A, Andersen JB, Marin JJG.

Br J Pharmacol. 2019 Mar;176(6):787-800. doi: 10.1111/bph.14563. Epub 2019 Feb 11.

PMID:
30592786
9.

Role of drug transporters in the sensitivity of acute myeloid leukemia to sorafenib.

Macias RIR, Sánchez-Martín A, Rodríguez-Macías G, Sánchez-Abarca LI, Lozano E, Herraez E, Odero MD, Díez-Martín JL, Marin JJG, Briz O.

Oncotarget. 2018 Jun 19;9(47):28474-28485. doi: 10.18632/oncotarget.25494. eCollection 2018 Jun 19.

10.

Interaction of glucocorticoids with FXR/FGF19/FGF21-mediated ileum-liver crosstalk.

Al-Aqil FA, Monte MJ, Peleteiro-Vigil A, Briz O, Rosales R, González R, Aranda CJ, Ocón B, Uriarte I, de Medina FS, Martinez-Augustín O, Avila MA, Marín JJG, Romero MR.

Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2927-2937. doi: 10.1016/j.bbadis.2018.06.003. Epub 2018 Jun 6.

11.

Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition.

Lozano E, Briz O, Macias RIR, Serrano MA, Marin JJG, Herraez E.

J Pers Med. 2018 Apr 16;8(2). pii: E14. doi: 10.3390/jpm8020014. Review.

12.

Molecular bases of the poor response of liver cancer to chemotherapy.

Marin JJG, Briz O, Herraez E, Lozano E, Asensio M, Di Giacomo S, Romero MR, Osorio-Padilla LM, Santos-Llamas AI, Serrano MA, Armengol C, Efferth T, Macias RIR.

Clin Res Hepatol Gastroenterol. 2018 Jun;42(3):182-192. doi: 10.1016/j.clinre.2017.12.006. Epub 2018 Mar 12. Review.

PMID:
29544679
13.

Chemoresistance and chemosensitization in cholangiocarcinoma.

Marin JJG, Lozano E, Herraez E, Asensio M, Di Giacomo S, Romero MR, Briz O, Serrano MA, Efferth T, Macias RIR.

Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1444-1453. doi: 10.1016/j.bbadis.2017.06.005. Epub 2017 Jul 7. Review.

14.

Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1.

Herraez E, Sanchez-Vicente L, Macias RIR, Briz O, Marin JJG.

Oncotarget. 2017 May 23;8(21):34617-34629. doi: 10.18632/oncotarget.16119.

15.

SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma.

Merino-Azpitarte M, Lozano E, Perugorria MJ, Esparza-Baquer A, Erice O, Santos-Laso Á, O'Rourke CJ, Andersen JB, Jiménez-Agüero R, Lacasta A, D'Amato M, Briz Ó, Jalan-Sakrikar N, Huebert RC, Thelen KM, Gradilone SA, Aransay AM, Lavín JL, Fernández-Barrena MG, Matheu A, Marzioni M, Gores GJ, Bujanda L, Marin JJG, Banales JM.

J Hepatol. 2017 Jul;67(1):72-83. doi: 10.1016/j.jhep.2017.02.017. Epub 2017 Feb 22.

16.

ACOX2 deficiency: An inborn error of bile acid synthesis identified in an adolescent with persistent hypertransaminasemia.

Monte MJ, Alonso-Peña M, Briz O, Herraez E, Berasain C, Argemi J, Prieto J, Marin JJG.

J Hepatol. 2017 Mar;66(3):581-588. doi: 10.1016/j.jhep.2016.11.005. Epub 2016 Nov 21.

PMID:
27884763
17.

Protective role of biliverdin against bile acid-induced oxidative stress in liver cells.

Gonzalez-Sanchez E, Perez MJ, Nytofte NS, Briz O, Monte MJ, Lozano E, Serrano MA, Marin JJG.

Free Radic Biol Med. 2016 Aug;97:466-477. doi: 10.1016/j.freeradbiomed.2016.06.016. Epub 2016 Jul 5.

PMID:
27387768
18.

Biodetection of potential genotoxic pollutants entering the human food chain through ashes used in livestock diets.

Sanchez-Vicente L, Herraez E, Briz O, Nogales R, Molina-Alcaide E, Marin JJ.

Food Chem. 2016 Aug 15;205:81-8. doi: 10.1016/j.foodchem.2016.02.160. Epub 2016 Mar 3.

PMID:
27006217
19.

Bile Acids in Physiology, Pathology and Pharmacology.

Marin JJ, Macias RI, Briz O, Banales JM, Monte MJ.

Curr Drug Metab. 2015;17(1):4-29. Review.

PMID:
26526836
20.

Role of drug transport and metabolism in the chemoresistance of acute myeloid leukemia.

Marin JJ, Briz O, Rodríguez-Macias G, Díez-Martín JL, Macias RI.

Blood Rev. 2016 Jan;30(1):55-64. doi: 10.1016/j.blre.2015.08.001. Epub 2015 Aug 18. Review.

PMID:
26321049
21.

Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT).

Lozano E, Monte MJ, Briz O, Hernández-Hernández A, Banales JM, Marin JJ, Macias RI.

J Control Release. 2015 Oct 28;216:93-102. doi: 10.1016/j.jconrel.2015.08.022. Epub 2015 Aug 14.

PMID:
26278512
22.

Mechanisms of Resistance to Chemotherapy in Gastric Cancer.

Marin JJ, Al-Abdulla R, Lozano E, Briz O, Bujanda L, Banales JM, Macias RI.

Anticancer Agents Med Chem. 2016;16(3):318-34. Review.

PMID:
26234359
23.

Molecular Bases of Chemoresistance in Cholangiocarcinoma.

Marin JJG, Lozano E, Briz O, Al-Abdulla R, Serrano MA, Macias RIR.

Curr Drug Targets. 2017;18(8):889-900. doi: 10.2174/1389450116666150223121508. Review.

PMID:
25706108
24.

On-chip copper-dielectric interference filters for manufacturing of ambient light and proximity CMOS sensors.

Frey L, Masarotto L, D'Aillon PG, Pellé C, Armand M, Marty M, Jamin-Mornet C, Lhostis S, Le Briz O.

Appl Opt. 2014 Jul 10;53(20):4493-502. doi: 10.1364/AO.53.004493.

PMID:
25090070
25.

The effect of acetaminophen on the expression of BCRP in trophoblast cells impairs the placental barrier to bile acids during maternal cholestasis.

Blazquez AG, Briz O, Gonzalez-Sanchez E, Perez MJ, Ghanem CI, Marin JJ.

Toxicol Appl Pharmacol. 2014 May 15;277(1):77-85. doi: 10.1016/j.taap.2014.02.019. Epub 2014 Mar 11.

PMID:
24631341
26.

The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy.

Marin JJ, Monte MJ, Blazquez AG, Macias RI, Serrano MA, Briz O.

Acta Pharmacol Sin. 2014 Jan;35(1):1-10. doi: 10.1038/aps.2013.131. Epub 2013 Dec 9. Review.

27.

Cocarcinogenic effects of intrahepatic bile acid accumulation in cholangiocarcinoma development.

Lozano E, Sanchez-Vicente L, Monte MJ, Herraez E, Briz O, Banales JM, Marin JJ, Macias RI.

Mol Cancer Res. 2014 Jan;12(1):91-100. doi: 10.1158/1541-7786.MCR-13-0503. Epub 2013 Nov 19.

28.

Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacology.

Lozano E, Herraez E, Briz O, Robledo VS, Hernandez-Iglesias J, Gonzalez-Hernandez A, Marin JJ.

Biomed Res Int. 2013;2013:692071. doi: 10.1155/2013/692071. Epub 2013 Jul 31. Review.

29.

Maternal cholestasis during pregnancy programs metabolic disease in offspring.

Papacleovoulou G, Abu-Hayyeh S, Nikolopoulou E, Briz O, Owen BM, Nikolova V, Ovadia C, Huang X, Vaarasmaki M, Baumann M, Jansen E, Albrecht C, Jarvelin MR, Marin JJ, Knisely AS, Williamson C.

J Clin Invest. 2013 Jul;123(7):3172-81. doi: 10.1172/JCI68927. Epub 2013 Jun 24.

30.

Activation of the nuclear receptor FXR enhances hepatocyte chemoprotection and liver tumor chemoresistance against genotoxic compounds.

Vaquero J, Briz O, Herraez E, Muntané J, Marin JJ.

Biochim Biophys Acta. 2013 Oct;1833(10):2212-9. doi: 10.1016/j.bbamcr.2013.05.006. Epub 2013 May 13.

31.

Expression of SLC22A1 variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib.

Herraez E, Lozano E, Macias RI, Vaquero J, Bujanda L, Banales JM, Marin JJ, Briz O.

Hepatology. 2013 Sep;58(3):1065-73. doi: 10.1002/hep.26425. Epub 2013 Jul 30.

PMID:
23532667
32.

ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds.

Rosales R, Monte MJ, Blazquez AG, Briz O, Marin JJ.

Biochem Pharmacol. 2012 Dec 15;84(12):1651-9. doi: 10.1016/j.bcp.2012.09.029. Epub 2012 Oct 3.

PMID:
23041646
33.

Cisplatin-induced chemoresistance in colon cancer cells involves FXR-dependent and FXR-independent up-regulation of ABC proteins.

Herraez E, Gonzalez-Sanchez E, Vaquero J, Romero MR, Serrano MA, Marin JJ, Briz O.

Mol Pharm. 2012 Sep 4;9(9):2565-76. doi: 10.1021/mp300178a. Epub 2012 Aug 1.

PMID:
22800197
34.

Chemoprevention, chemotherapy, and chemoresistance in colorectal cancer.

Marin JJ, Sanchez de Medina F, Castaño B, Bujanda L, Romero MR, Martinez-Augustin O, Moral-Avila RD, Briz O.

Drug Metab Rev. 2012 May;44(2):148-72. doi: 10.3109/03602532.2011.638303. Review.

PMID:
22497631
35.

Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle.

Molina-Jimenez F, Benedicto I, Dao Thi VL, Gondar V, Lavillette D, Marin JJ, Briz O, Moreno-Otero R, Aldabe R, Baumert TF, Cosset FL, Lopez-Cabrera M, Majano PL.

Virology. 2012 Mar 30;425(1):31-9. doi: 10.1016/j.virol.2011.12.021. Epub 2012 Jan 24.

36.

Genetic variants in genes involved in mechanisms of chemoresistance to anticancer drugs.

Marin JJ, Briz O, Monte MJ, Blazquez AG, Macias RI.

Curr Cancer Drug Targets. 2012 May;12(4):402-38. Review.

PMID:
22229248
37.

Characterization of the role of ABCG2 as a bile acid transporter in liver and placenta.

Blazquez AG, Briz O, Romero MR, Rosales R, Monte MJ, Vaquero J, Macias RI, Cassio D, Marin JJ.

Mol Pharmacol. 2012 Feb;81(2):273-83. doi: 10.1124/mol.111.075143. Epub 2011 Nov 17.

PMID:
22096226
38.

A homozygous nonsense mutation (c.214C->A) in the biliverdin reductase alpha gene (BLVRA) results in accumulation of biliverdin during episodes of cholestasis.

Nytofte NS, Serrano MA, Monte MJ, Gonzalez-Sanchez E, Tumer Z, Ladefoged K, Briz O, Marin JJ.

J Med Genet. 2011 Apr;48(4):219-25. doi: 10.1136/jmg.2009.074567. Epub 2011 Jan 28.

PMID:
21278388
39.

Further characterization of the electrogenicity and pH sensitivity of the human organic anion-transporting polypeptides OATP1B1 and OATP1B3.

Martinez-Becerra P, Briz O, Romero MR, Macias RI, Perez MJ, Sancho-Mateo C, Lostao MP, Fernandez-Abalos JM, Marin JJ.

Mol Pharmacol. 2011 Mar;79(3):596-607. doi: 10.1124/mol.110.069971. Epub 2010 Dec 20.

PMID:
21173039
40.

Molecular bases of liver cancer refractoriness to pharmacological treatment.

Marin JJ, Romero MR, Briz O.

Curr Med Chem. 2010;17(8):709-40. Review.

PMID:
20088759
41.

Overview of the molecular bases of resistance to chemotherapy in liver and gastrointestinal tumours.

Marin JJ, Romero MR, Martinez-Becerra P, Herraez E, Briz O.

Curr Mol Med. 2009 Dec;9(9):1108-29. Review.

PMID:
19747110
42.

Bile-acid-induced cell injury and protection.

Perez MJ, Briz O.

World J Gastroenterol. 2009 Apr 14;15(14):1677-89. Review.

43.

Hepatobiliary transporters in the pharmacology and toxicology of anticancer drugs.

Marin JJ, Briz O, Perez MJ, Romero MR, Monte MJ.

Front Biosci (Landmark Ed). 2009 Jan 1;14:4257-80. Review.

PMID:
19273349
44.

Importance and limitations of chemotherapy among the available treatments for gastrointestinal tumours.

Marin JJ, Romero MR, Blazquez AG, Herraez E, Keck E, Briz O.

Anticancer Agents Med Chem. 2009 Feb;9(2):162-84. Review.

PMID:
19199863
45.

Molecular pathogenesis of intrahepatic cholestasis of pregnancy.

Arrese M, Macias RI, Briz O, Perez MJ, Marin JJ.

Expert Rev Mol Med. 2008 Mar 28;10:e9. doi: 10.1017/S1462399408000628. Review.

PMID:
18371245
46.

Molecular bases of the fetal liver-placenta-maternal liver excretory pathway for cholephilic compounds.

Marin JJ, Macias RI, Briz O, Perez MJ, Blazquez AG, Arrese M, Serrano MA.

Liver Int. 2008 Apr;28(4):435-54. doi: 10.1111/j.1478-3231.2008.01680.x. Review.

PMID:
18339071
47.
48.

Novel bile acid derivatives (BANBs) with cytostatic activity obtained by conjugation of their side chain with nitrogenated bases.

Vallejo M, Castro MA, Medarde M, Macias RI, Romero MR, El-Mir MY, Monte MJ, Briz O, Serrano MA, Marin JJ.

Biochem Pharmacol. 2007 May 1;73(9):1394-404. Epub 2006 Dec 28.

PMID:
17257589
49.

Inhibition of the intestinal absorption of bile acids using cationic derivatives: mechanism and repercussions.

Vicens M, Macias RI, Briz O, Rodriguez A, El-Mir MY, Medarde M, Marin JJ.

Biochem Pharmacol. 2007 Feb 1;73(3):394-404. Epub 2006 Oct 20.

PMID:
17134679
50.

OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes?

Briz O, Romero MR, Martinez-Becerra P, Macias RI, Perez MJ, Jimenez F, San Martin FG, Marin JJ.

J Biol Chem. 2006 Oct 13;281(41):30326-35. Epub 2006 Jul 28.

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