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Items: 1 to 50 of 76

1.

High throughput screening of serum γ-glutamyl dipeptides for risk assessment of nonalcoholic steatohepatitis with impaired glutathione salvage pathway.

Saoi M, Sasaki K, Sagawa H, Abe K, Kogiso T, Tokushige K, Hashimoto E, Ohashi Y, Britz-McKibbin P.

J Proteome Res. 2019 Sep 4. doi: 10.1021/acs.jproteome.9b00405. [Epub ahead of print]

PMID:
31483669
2.

New Advances in Amino Acid Profiling in Biological Samples by Capillary Electrophoresis-Mass Spectrometry.

Shanmuganathan M, Britz-McKibbin P.

Methods Mol Biol. 2019;2030:327-350. doi: 10.1007/978-1-4939-9639-1_25.

PMID:
31347129
3.

Metabolic Perturbations from Step Reduction in Older Persons at Risk for Sarcopenia: Plasma Biomarkers of Abrupt Changes in Physical Activity.

Saoi M, Li A, McGlory C, Stokes T, von Allmen MT, Phillips SM, Britz-McKibbin P.

Metabolites. 2019 Jul 8;9(7). pii: E134. doi: 10.3390/metabo9070134.

4.

Metabolomics reveals elevated urinary excretion of collagen degradation and epithelial cell turnover products in irritable bowel syndrome patients.

Yamamoto M, Pinto-Sanchez MI, Bercik P, Britz-McKibbin P.

Metabolomics. 2019 May 20;15(6):82. doi: 10.1007/s11306-019-1543-0.

PMID:
31111238
5.

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-capillary Electrophoresis Mass Spectrometry.

Shanmuganathan M, Macklai S, Barrenas Cárdenas C, Kroezen Z, Kim M, Zizek W, Lee H, Britz-McKibbin P.

J Vis Exp. 2019 Apr 23;(146). doi: 10.3791/58986. Erratum in: J Vis Exp. 2019 May 16;(147):.

PMID:
31081805
6.

High-fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers.

Gohir W, Kennedy KM, Wallace JG, Saoi M, Bellissimo CJ, Britz-McKibbin P, Petrik JJ, Surette MG, Sloboda DM.

J Physiol. 2019 Jun;597(12):3029-3051. doi: 10.1113/JP277353. Epub 2019 May 13.

PMID:
31081119
7.

New Advances for Newborn Screening of Inborn Errors of Metabolism by Capillary Electrophoresis-Mass Spectrometry (CE-MS).

Shanmuganathan M, Britz-McKibbin P.

Methods Mol Biol. 2019;1972:139-163. doi: 10.1007/978-1-4939-9213-3_10.

PMID:
30847789
8.

Characterization of the Human Skeletal Muscle Metabolome for Elucidating the Mechanisms of Bicarbonate Ingestion on Strenuous Interval Exercise.

Saoi M, Percival M, Nemr C, Li A, Gibala M, Britz-McKibbin P.

Anal Chem. 2019 Apr 2;91(7):4709-4718. doi: 10.1021/acs.analchem.9b00149. Epub 2019 Mar 18.

PMID:
30835436
9.

Urinary 1-hydroxypyrene and Skin Contamination in Firefighters Deployed to the Fort McMurray Fire.

Cherry N, Aklilu YA, Beach J, Britz-McKibbin P, Elbourne R, Galarneau JM, Gill B, Kinniburgh D, Zhang X.

Ann Work Expo Health. 2019 Apr 19;63(4):448-458. doi: 10.1093/annweh/wxz006.

10.

Urinary hydroxypyrene determination for biomonitoring of firefighters deployed at the Fort McMurray wildfire: an inter-laboratory method comparison.

Gill B, Mell A, Shanmuganathan M, Jobst K, Zhang X, Kinniburgh D, Cherry N, Britz-McKibbin P.

Anal Bioanal Chem. 2019 Mar;411(7):1397-1407. doi: 10.1007/s00216-018-01569-1. Epub 2019 Jan 25.

PMID:
30683964
11.

Robust Method for High-Throughput Screening of Fatty Acids by Multisegment Injection-Nonaqueous Capillary Electrophoresis-Mass Spectrometry with Stringent Quality Control.

Azab S, Ly R, Britz-McKibbin P.

Anal Chem. 2019 Feb 5;91(3):2329-2336. doi: 10.1021/acs.analchem.8b05054. Epub 2019 Jan 7.

PMID:
30570251
12.

Metabolic Signatures of Cystic Fibrosis Identified in Dried Blood Spots For Newborn Screening Without Carrier Identification.

DiBattista A, McIntosh N, Lamoureux M, Al-Dirbashi OY, Chakraborty P, Britz-McKibbin P.

J Proteome Res. 2019 Mar 1;18(3):841-854. doi: 10.1021/acs.jproteome.8b00351. Epub 2019 Jan 7.

PMID:
30507207
13.

High Throughput Screening Method for Systematic Surveillance of Drugs of Abuse by Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry.

DiBattista A, Rampersaud D, Lee H, Kim M, Britz-McKibbin P.

Anal Chem. 2017 Nov 7;89(21):11853-11861. doi: 10.1021/acs.analchem.7b03590. Epub 2017 Oct 27.

PMID:
28981253
14.

The Sweat Metabolome of Screen-Positive Cystic Fibrosis Infants: Revealing Mechanisms beyond Impaired Chloride Transport.

Macedo AN, Mathiaparanam S, Brick L, Keenan K, Gonska T, Pedder L, Hill S, Britz-McKibbin P.

ACS Cent Sci. 2017 Aug 23;3(8):904-913. doi: 10.1021/acscentsci.7b00299. Epub 2017 Jul 31.

15.

Temporal Signal Pattern Recognition in Mass Spectrometry: A Method for Rapid Identification and Accurate Quantification of Biomarkers for Inborn Errors of Metabolism with Quality Assurance.

DiBattista A, McIntosh N, Lamoureux M, Al-Dirbashi OY, Chakraborty P, Britz-McKibbin P.

Anal Chem. 2017 Aug 1;89(15):8112-8121. doi: 10.1021/acs.analchem.7b01727. Epub 2017 Jul 11.

PMID:
28648083
16.

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice.

De Palma G, Lynch MD, Lu J, Dang VT, Deng Y, Jury J, Umeh G, Miranda PM, Pigrau Pastor M, Sidani S, Pinto-Sanchez MI, Philip V, McLean PG, Hagelsieb MG, Surette MG, Bergonzelli GE, Verdu EF, Britz-McKibbin P, Neufeld JD, Collins SM, Bercik P.

Sci Transl Med. 2017 Mar 1;9(379). pii: eaaf6397. doi: 10.1126/scitranslmed.aaf6397.

PMID:
28251905
17.

Robust and High-Throughput Method for Anionic Metabolite Profiling: Preventing Polyimide Aminolysis and Capillary Breakages under Alkaline Conditions in Capillary Electrophoresis-Mass Spectrometry.

Yamamoto M, Ly R, Gill B, Zhu Y, Moran-Mirabal J, Britz-McKibbin P.

Anal Chem. 2016 Nov 1;88(21):10710-10719. Epub 2016 Oct 10.

PMID:
27677202
18.

Allosteric Sensing of Fatty Acid Binding by NMR: Application to Human Serum Albumin.

Jafari N, Ahmed R, Gloyd M, Bloomfield J, Britz-McKibbin P, Melacini G.

J Med Chem. 2016 Aug 25;59(16):7457-65. doi: 10.1021/acs.jmedchem.6b00410. Epub 2016 Aug 3.

PMID:
27429126
19.

Evaluation of Firefighter Exposure to Wood Smoke during Training Exercises at Burn Houses.

Fernando S, Shaw L, Shaw D, Gallea M, VandenEnden L, House R, Verma DK, Britz-McKibbin P, McCarry BE.

Environ Sci Technol. 2016 Feb 2;50(3):1536-43. doi: 10.1021/acs.est.5b04752. Epub 2016 Jan 20.

PMID:
26726952
20.

Metabolomics Reveals Metabolically Healthy and Unhealthy Obese Individuals Differ in their Response to a Caloric Challenge.

Badoud F, Lam KP, Perreault M, Zulyniak MA, Britz-McKibbin P, Mutch DM.

PLoS One. 2015 Aug 14;10(8):e0134613. doi: 10.1371/journal.pone.0134613. eCollection 2015.

21.

Interlaboratory study to evaluate the robustness of capillary electrophoresis-mass spectrometry for peptide mapping.

Wenz C, Barbas C, López-Gonzálvez Á, Garcia A, Benavente F, Sanz-Nebot V, Blanc T, Freckleton G, Britz-McKibbin P, Shanmuganathan M, de l'Escaille F, Far J, Haselberg R, Huang S, Huhn C, Pattky M, Michels D, Mou S, Yang F, Neusuess C, Tromsdorf N, Baidoo EEK, Keasling JD, Park SS.

J Sep Sci. 2015 Sep;38(18):3262-3270. doi: 10.1002/jssc.201500551. Epub 2015 Aug 11.

PMID:
26147246
22.

Introducing the USA Plant, Algae and Microbial Metabolomics Research Coordination Network (PAMM-NET).

Sumner LW, Styczynski M, McLean J, Fiehn O, Jander G, Liao J, Sumner S, Britz-McKibbin P, Welti R, Jones AD, Dorrestein PC, Bearden D, Kaddurah-Daouk R.

Metabolomics. 2015 Feb;11(1):3-5. doi: 10.1007/s11306-014-0755-6. Epub 2014 Dec 20. No abstract available.

23.

Multiplexed separations for biomarker discovery in metabolomics: Elucidating adaptive responses to exercise training.

Kuehnbaum NL, Gillen JB, Kormendi A, Lam KP, DiBattista A, Gibala MJ, Britz-McKibbin P.

Electrophoresis. 2015 Sep;36(18):2226-2236. doi: 10.1002/elps.201400604. Epub 2015 May 20.

PMID:
25630301
24.

A robust method for iodine status determination in epidemiological studies by capillary electrophoresis.

de Macedo AN, Teo K, Mente A, McQueen MJ, Zeidler J, Poirier P, Lear SA, Wielgosz A, Britz-McKibbin P.

Anal Chem. 2014 Oct 21;86(20):10010-5. doi: 10.1021/ac503231u. Epub 2014 Oct 8.

PMID:
25280130
25.

Personalized metabolomics for predicting glucose tolerance changes in sedentary women after high-intensity interval training.

Kuehnbaum NL, Gillen JB, Gibala MJ, Britz-McKibbin P.

Sci Rep. 2014 Aug 28;4:6166. doi: 10.1038/srep06166.

26.

Serum and adipose tissue amino acid homeostasis in the metabolically healthy obese.

Badoud F, Lam KP, DiBattista A, Perreault M, Zulyniak MA, Cattrysse B, Stephenson S, Britz-McKibbin P, Mutch DM.

J Proteome Res. 2014 Jul 3;13(7):3455-66. doi: 10.1021/pr500416v. Epub 2014 Jun 23.

PMID:
24933025
27.

Multisegment injection-capillary electrophoresis-mass spectrometry: a high-throughput platform for metabolomics with high data fidelity.

Kuehnbaum NL, Kormendi A, Britz-McKibbin P.

Anal Chem. 2013 Nov 19;85(22):10664-9. doi: 10.1021/ac403171u. Epub 2013 Nov 6.

PMID:
24195601
28.

Strong anion determination in biological fluids by capillary electrophoresis for clinical diagnostics.

de Macedo AN, Jiwa MI, Macri J, Belostotsky V, Hill S, Britz-McKibbin P.

Anal Chem. 2013 Nov 19;85(22):11112-20. doi: 10.1021/ac402975q. Epub 2013 Oct 29.

PMID:
24127785
29.

High quality drug screening by capillary electrophoresis: a review.

Shanmuganathan M, Britz-McKibbin P.

Anal Chim Acta. 2013 Apr 22;773:24-36. doi: 10.1016/j.aca.2013.01.061. Epub 2013 Feb 11. Review.

PMID:
23561903
30.

New advances in separation science for metabolomics: resolving chemical diversity in a post-genomic era.

Kuehnbaum NL, Britz-McKibbin P.

Chem Rev. 2013 Apr 10;113(4):2437-68. doi: 10.1021/cr300484s. Epub 2013 Mar 18. Review. No abstract available.

PMID:
23506082
31.
32.

Functional screening of pharmacological chaperones via restoration of enzyme activity upon denaturation.

Shanmuganathan M, Britz-McKibbin P.

Biochemistry. 2012 Oct 2;51(39):7651-3. doi: 10.1021/bi301223f. Epub 2012 Sep 19.

PMID:
22970758
33.

Control of hydroxyproline catabolism in Sinorhizobium meliloti.

White CE, Gavina JM, Morton R, Britz-McKibbin P, Finan TM.

Mol Microbiol. 2012 Sep;85(6):1133-47. doi: 10.1111/j.1365-2958.2012.08164.x. Epub 2012 Jul 27.

34.

Functional screening of cytochrome P450 activity and uncoupling by capillary electrophoresis.

Harskamp J, Britz-McKibbin P, Wilson JY.

Anal Chem. 2012 Jan 17;84(2):862-6. doi: 10.1021/ac202787n. Epub 2011 Dec 21.

PMID:
22148186
35.

New advances in amino acid profiling by capillary electrophoresis-electrospray ionization-mass spectrometry.

Britz-McKibbin P.

Methods Mol Biol. 2012;828:83-99. doi: 10.1007/978-1-61779-445-2_9.

PMID:
22125139
36.

Comprehensive profiling of free and conjugated estrogens by capillary electrophoresis-time of flight/mass spectrometry.

Kuehnbaum NL, Britz-McKibbin P.

Anal Chem. 2011 Nov 1;83(21):8063-8. doi: 10.1021/ac201980w. Epub 2011 Oct 7.

PMID:
21967655
37.

Inhibitor screening of pharmacological chaperones for lysosomal β-glucocerebrosidase by capillary electrophoresis.

Shanmuganathan M, Britz-McKibbin P.

Anal Bioanal Chem. 2011 Mar;399(8):2843-53. doi: 10.1007/s00216-011-4671-6. Epub 2011 Feb 1.

PMID:
21286689
38.

Capillary electrophoresis-electrospray ionization-mass spectrometry (CE-ESI-MS)-based metabolomics.

Britz-McKibbin P.

Methods Mol Biol. 2011;708:229-46. doi: 10.1007/978-1-61737-985-7_14.

PMID:
21207294
39.

Comprehensive plasma thiol redox status determination for metabolomics.

D'Agostino LA, Lam KP, Lee R, Britz-McKibbin P.

J Proteome Res. 2011 Feb 4;10(2):592-603. doi: 10.1021/pr100771g. Epub 2010 Nov 29.

PMID:
21053925
40.

Determination of 4-hydroxyproline-2-epimerase activity by capillary electrophoresis: A stereoselective platform for inhibitor screening of amino acid isomerases.

Gavina JM, White CE, Finan TM, Britz-McKibbin P.

Electrophoresis. 2010 Aug;31(16):2831-7. doi: 10.1002/elps.201000187.

PMID:
20665524
41.

Direct analysis of polyols using 3-nitrophenylboronic acid in capillary electrophoresis: thermodynamic and electrokinetic principles of molecular recognition.

Fei F, Britz-McKibbin P.

Anal Bioanal Chem. 2010 Oct;398(3):1349-56. doi: 10.1007/s00216-010-4038-4. Epub 2010 Jul 28.

PMID:
20665005
45.
47.

Label-free assay for thermodynamic analysis of protein-ligand interactions: a multivariate strategy for allosteric ligand screening.

Gavina JM, Mazhab-Jafari MT, Melacini G, Britz-McKibbin P.

Biochemistry. 2009 Jan 20;48(2):223-5. doi: 10.1021/bi802121g.

PMID:
19113833
48.

New advances in on-line sample preconcentration by capillary electrophoresis using dynamic pH junction.

Ptolemy AS, Britz-McKibbin P.

Analyst. 2008 Dec;133(12):1643-8. doi: 10.1039/b808236g. Epub 2008 Oct 9.

PMID:
19082065
49.

Electrokinetic probes for single-step screening of polyol stereoisomers: the virtues of ternary boronate ester complex formation.

Kaiser C, Segui-Lines G, D'Amaral JC, Ptolemy AS, Britz-McKibbin P.

Chem Commun (Camb). 2008 Jan 21;(3):338-40.

PMID:
18399200
50.

High-throughput screening of holoprotein conformational stability by dynamic ligand exchange-affinity capillary electrophoresis.

Seguí-Lines G, Gavina JM, D'Amaral JC, Britz-McKibbin P.

Analyst. 2007 Aug;132(8):741-4. Epub 2007 Jun 12.

PMID:
17646872

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