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Items: 1 to 50 of 275

1.

Altered Cognitive Flexibility and Synaptic Plasticity in the Rat Prefrontal Cortex after Exposure to Low (≤15 cGy) Doses of 28Si Radiation.

Britten RA, Duncan VD, Fesshaye A, Rudobeck E, Nelson GA, Vlkolinsky R.

Radiat Res. 2020 Feb 3. doi: 10.1667/RR15458.1. [Epub ahead of print]

PMID:
32011211
2.

Response to the Commentary from Bevelacqua et al.

Limoli CL, Britten R, Baulch J, Borak T.

eNeuro. 2020 Feb 14;7(1). pii: ENEURO.0439-19.2019. doi: 10.1523/ENEURO.0439-19.2019. Print 2020 Jan/Feb. No abstract available.

3.

Sleep fragmentation exacerbates executive function impairments induced by protracted low dose rate neutron exposure.

Britten RA, Duncan VD, Fesshaye AS, Wellman LL, Fallgren CM, Sanford LD.

Int J Radiat Biol. 2019 Dec 6:1-11. doi: 10.1080/09553002.2019.1694190. [Epub ahead of print]

PMID:
31724895
4.

New Concerns for Neurocognitive Function during Deep Space Exposures to Chronic, Low Dose-Rate, Neutron Radiation.

Acharya MM, Baulch JE, Klein PM, Baddour AAD, Apodaca LA, Kramár EA, Alikhani L, Garcia C Jr, Angulo MC, Batra RS, Fallgren CM, Borak TB, Stark CEL, Wood MA, Britten RA, Soltesz I, Limoli CL.

eNeuro. 2019 Aug 22;6(4). pii: ENEURO.0094-19.2019. doi: 10.1523/ENEURO.0094-19.2019. Print 2019 Jul/Aug. Erratum in: eNeuro. 2019 Oct 18;6(5):.

5.

Exposure to ≤15 cGy of 600 MeV/n 56Fe Particles Impairs Rule Acquisition but not Long-Term Memory in the Attentional Set-Shifting Assay.

Jewell JS, Duncan VD, Fesshaye A, Tondin A, Macadat E, Britten RA.

Radiat Res. 2018 Dec;190(6):565-575. doi: 10.1667/RR15085.1. Epub 2018 Nov 8.

PMID:
30407900
6.

Impaired Attentional Set-Shifting Performance after Exposure to 5 cGy of 600 MeV/n 28Si Particles.

Britten RA, Jewell JS, Duncan VD, Hadley MM, Macadat E, Musto AE, Tessa C.

Radiat Res. 2018 Mar;189(3):273-282. doi: 10.1667/RR14627.1. Epub 2018 Jan 8.

PMID:
29309264
7.

Quantitative Proteomic Analysis of the Hippocampus of Rats with GCR-Induced Spatial Memory Impairment.

Dutta SM, Hadley MM, Peterman S, Jewell JS, Duncan VD, Britten RA.

Radiat Res. 2018 Feb;189(2):136-145. doi: 10.1667/RR14822.1. Epub 2017 Dec 5.

PMID:
29206597
8.

Changes in the Hippocampal Proteome Associated with Spatial Memory Impairment after Exposure to Low (20 cGy) Doses of 1 GeV/n 56Fe Radiation.

Britten RA, Jewell JS, Davis LK, Miller VD, Hadley MM, Semmes OJ, Lonart G, Dutta SM.

Radiat Res. 2017 Mar;187(3):287-297. doi: 10.1667/RR14067.1. Epub 2017 Feb 3.

PMID:
28156212
9.

Spatial Memory Performance of Socially Mature Wistar Rats is Impaired after Exposure to Low (5 cGy) Doses of 1 GeV/n 48Ti Particles.

Britten RA, Jewell JS, Duncan VD, Davis LK, Hadley MM, Wyrobek AJ.

Radiat Res. 2017 Jan;187(1):60-65. doi: 10.1667/RR14550.1. Epub 2017 Jan 13.

PMID:
28085638
10.

Cosmic radiation exposure and persistent cognitive dysfunction.

Parihar VK, Allen BD, Caressi C, Kwok S, Chu E, Tran KK, Chmielewski NN, Giedzinski E, Acharya MM, Britten RA, Baulch JE, Limoli CL.

Sci Rep. 2016 Oct 10;6:34774. doi: 10.1038/srep34774.

11.

Performance in hippocampus- and PFC-dependent cognitive domains are not concomitantly impaired in rats exposed to 20cGy of 1GeV/n (56)Fe particles.

Britten RA, Miller VD, Hadley MM, Jewell JS, Macadat E.

Life Sci Space Res (Amst). 2016 Aug;10:17-22. doi: 10.1016/j.lssr.2016.06.005. Epub 2016 Jun 27.

PMID:
27662783
12.

Individual variations in dose response for spatial memory learning among outbred wistar rats exposed from 5 to 20 cGy of (56) Fe particles.

Wyrobek AJ, Britten RA.

Environ Mol Mutagen. 2016 Jun;57(5):331-40. doi: 10.1002/em.22018. Epub 2016 May 30.

PMID:
27237589
13.

Galactic cosmic ray simulation at the NASA Space Radiation Laboratory.

Norbury JW, Schimmerling W, Slaba TC, Azzam EI, Badavi FF, Baiocco G, Benton E, Bindi V, Blakely EA, Blattnig SR, Boothman DA, Borak TB, Britten RA, Curtis S, Dingfelder M, Durante M, Dynan WS, Eisch AJ, Robin Elgart S, Goodhead DT, Guida PM, Heilbronn LH, Hellweg CE, Huff JL, Kronenberg A, La Tessa C, Lowenstein DI, Miller J, Morita T, Narici L, Nelson GA, Norman RB, Ottolenghi A, Patel ZS, Reitz G, Rusek A, Schreurs AS, Scott-Carnell LA, Semones E, Shay JW, Shurshakov VA, Sihver L, Simonsen LC, Story MD, Turker MS, Uchihori Y, Williams J, Zeitlin CJ.

Life Sci Space Res (Amst). 2016 Feb;8:38-51. doi: 10.1016/j.lssr.2016.02.001. Epub 2016 Feb 17.

14.

Impaired Spatial Memory Performance in Adult Wistar Rats Exposed to Low (5-20 cGy) Doses of 1 GeV/n (56)Fe Particles.

Britten RA, Jewell JS, Miller VD, Davis LK, Hadley MM, Wyrobek AJ.

Radiat Res. 2016 Mar;185(3):332-7. doi: 10.1667/RR14120.1. Epub 2016 Mar 4.

PMID:
26943453
15.

Exposure to Mission-Relevant Doses of 1 GeV/n (48)Ti Particles Impairs Attentional Set-Shifting Performance in Retired Breeder Rats.

Hadley MM, Davis LK, Jewell JS, Miller VD, Britten RA.

Radiat Res. 2016 Jan;185(1):13-9. doi: 10.1667/RR14086.1. Epub 2015 Dec 31.

PMID:
26720801
16.

Exposure to mission relevant doses of 1 GeV/Nucleon (56)Fe particles leads to impairment of attentional set-shifting performance in socially mature rats.

Britten RA, Davis LK, Jewell JS, Miller VD, Hadley MM, Sanford LD, Machida M, Lonart G.

Radiat Res. 2014 Sep;182(3):292-8. doi: 10.1667/RR3766.1. Epub 2014 Jul 16.

17.

FieldML, a proposed open standard for the Physiome project for mathematical model representation.

Britten RD, Christie GR, Little C, Miller AK, Bradley C, Wu A, Yu T, Hunter P, Nielsen P.

Med Biol Eng Comput. 2013 Nov;51(11):1191-207. doi: 10.1007/s11517-013-1097-7. Epub 2013 Jul 31.

18.

Variations in the RBE for cell killing along the depth-dose profile of a modulated proton therapy beam.

Britten RA, Nazaryan V, Davis LK, Klein SB, Nichiporov D, Mendonca MS, Wolanski M, Nie X, George J, Keppel C.

Radiat Res. 2013 Jan;179(1):21-8. doi: 10.1667/RR2737.1. Epub 2012 Nov 13.

PMID:
23148508
19.

Executive function in rats is impaired by low (20 cGy) doses of 1 GeV/u (56)Fe particles.

Lonart G, Parris B, Johnson AM, Miles S, Sanford LD, Singletary SJ, Britten RA.

Radiat Res. 2012 Oct;178(4):289-94. Epub 2012 Aug 10.

PMID:
22880624
20.

Declarative representation of uncertainty in mathematical models.

Miller AK, Britten RD, Nielsen PM.

PLoS One. 2012;7(7):e39721. doi: 10.1371/journal.pone.0039721. Epub 2012 Jul 3.

21.

Low (20 cGy) doses of 1 GeV/u (56)Fe--particle radiation lead to a persistent reduction in the spatial learning ability of rats.

Britten RA, Davis LK, Johnson AM, Keeney S, Siegel A, Sanford LD, Singletary SJ, Lonart G.

Radiat Res. 2012 Feb;177(2):146-51. Epub 2011 Nov 11.

PMID:
22077338
22.

OpenCMISS: a multi-physics & multi-scale computational infrastructure for the VPH/Physiome project.

Bradley C, Bowery A, Britten R, Budelmann V, Camara O, Christie R, Cookson A, Frangi AF, Gamage TB, Heidlauf T, Krittian S, Ladd D, Little C, Mithraratne K, Nash M, Nickerson D, Nielsen P, Nordbø O, Omholt S, Pashaei A, Paterson D, Rajagopal V, Reeve A, Röhrle O, Safaei S, Sebastián R, Steghöfer M, Wu T, Yu T, Zhang H, Hunter P.

Prog Biophys Mol Biol. 2011 Oct;107(1):32-47. doi: 10.1016/j.pbiomolbio.2011.06.015. Epub 2011 Jul 7.

PMID:
21762717
23.

The Cardiac Atlas Project--an imaging database for computational modeling and statistical atlases of the heart.

Fonseca CG, Backhaus M, Bluemke DA, Britten RD, Chung JD, Cowan BR, Dinov ID, Finn JP, Hunter PJ, Kadish AH, Lee DC, Lima JA, Medrano-Gracia P, Shivkumar K, Suinesiaputra A, Tao W, Young AA.

Bioinformatics. 2011 Aug 15;27(16):2288-95. doi: 10.1093/bioinformatics/btr360. Epub 2011 Jul 6.

24.

Minimum Information About a Simulation Experiment (MIASE).

Waltemath D, Adams R, Beard DA, Bergmann FT, Bhalla US, Britten R, Chelliah V, Cooling MT, Cooper J, Crampin EJ, Garny A, Hoops S, Hucka M, Hunter P, Klipp E, Laibe C, Miller AK, Moraru I, Nickerson D, Nielsen P, Nikolski M, Sahle S, Sauro HM, Schmidt H, Snoep JL, Tolle D, Wolkenhauer O, Le Novère N.

PLoS Comput Biol. 2011 Apr;7(4):e1001122. doi: 10.1371/journal.pcbi.1001122. Epub 2011 Apr 28. No abstract available.

25.

Revision history aware repositories of computational models of biological systems.

Miller AK, Yu T, Britten R, Cooling MT, Lawson J, Cowan D, Garny A, Halstead MD, Hunter PJ, Nickerson DP, Nunns G, Wimalaratne SM, Nielsen PM.

BMC Bioinformatics. 2011 Jan 14;12:22. doi: 10.1186/1471-2105-12-22.

26.

The Physiome Model Repository 2.

Yu T, Lloyd CM, Nickerson DP, Cooling MT, Miller AK, Garny A, Terkildsen JR, Lawson J, Britten RD, Hunter PJ, Nielsen PM.

Bioinformatics. 2011 Mar 1;27(5):743-4. doi: 10.1093/bioinformatics/btq723. Epub 2011 Jan 6.

PMID:
21216774
27.

Transposable element insertions have strongly affected human evolution.

Britten RJ.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19945-8. doi: 10.1073/pnas.1014330107. Epub 2010 Nov 1.

28.

Low (60 cGy) doses of (56)Fe HZE-particle radiation lead to a persistent reduction in the glutamatergic readily releasable pool in rat hippocampal synaptosomes.

Machida M, Lonart G, Britten RA.

Radiat Res. 2010 Nov;174(5):618-23. doi: 10.1667/RR1988.1. Epub 2010 Aug 12.

PMID:
20726706
29.

Sharing and reusing cardiovascular anatomical models over the Web: a step towards the implementation of the virtual physiological human project.

Gianni D, McKeever S, Yu T, Britten R, Delingette H, Frangi A, Hunter P, Smith N.

Philos Trans A Math Phys Eng Sci. 2010 Jun 28;368(1921):3039-56. doi: 10.1098/rsta.2010.0025.

PMID:
20478920
30.

Climate change and the integrity of science.

Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J Jr, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS 3rd, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB Jr, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE Jr, Wu C, Wunsch C, Zoback ML.

Science. 2010 May 7;328(5979):689-90. doi: 10.1126/science.328.5979.689. No abstract available. Erratum in: Science. 2010 May 14;328(5980):826.

31.

An overview of the CellML API and its implementation.

Miller AK, Marsh J, Reeve A, Garny A, Britten R, Halstead M, Cooper J, Nickerson DP, Nielsen PF.

BMC Bioinformatics. 2010 Apr 8;11:178. doi: 10.1186/1471-2105-11-178.

32.

The identification of serum biomarkers of high-let radiation exposure and biological sequelae.

Britten RA, Mitchell S, Johnson AM, Singletary SJ, Keeney SK, Nyalwidhe JO, Karbassi ID, Lonart G, Sanford LD, Drake RR.

Health Phys. 2010 Feb;98(2):196-203. doi: 10.1097/HP.0b013e3181acff7c.

PMID:
20065683
33.

CellML metadata standards, associated tools and repositories.

Beard DA, Britten R, Cooling MT, Garny A, Halstead MD, Hunter PJ, Lawson J, Lloyd CM, Marsh J, Miller A, Nickerson DP, Nielsen PM, Nomura T, Subramanium S, Wimalaratne SM, Yu T.

Philos Trans A Math Phys Eng Sci. 2009 May 28;367(1895):1845-67. doi: 10.1098/rsta.2008.0310.

34.

Almost all human genes resulted from ancient duplication.

Britten RJ.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19027-32. Epub 2006 Dec 4.

35.

Transposable elements have contributed to thousands of human proteins.

Britten R.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1798-803. Epub 2006 Jan 27.

36.

Identification of reproducible low mass SELDI protein profiles specific to cisplatin resistance in human ovarian cancer cells.

Britten RA, Hardy C, Vlahou A, Gregory B, Giri PS, Drake R.

Oncol Rep. 2005 Nov;14(5):1323-30.

PMID:
16211304
37.

The majority of human genes have regions repeated in other human genes.

Britten RJ.

Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5466-70. Epub 2005 Mar 31.

38.

Coding sequences of functioning human genes derived entirely from mobile element sequences.

Britten RJ.

Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16825-30. Epub 2004 Nov 16.

39.

A novel intravesical therapy for superficial bladder cancer in an orthotopic model: oncolytic reovirus therapy.

Hanel EG, Xiao Z, Wong KK, Lee PW, Britten RA, Moore RB.

J Urol. 2004 Nov;172(5 Pt 1):2018-22.

PMID:
15540781
40.

Majority of divergence between closely related DNA samples is due to indels.

Britten RJ, Rowen L, Williams J, Cameron RA.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4661-5. Epub 2003 Apr 2.

41.

Modification of radiosensitivity following chemotherapy exposure: potential implications for combined-modality therapy.

Britten RA.

Cancer Treat Res. 2002;112:285-303. Review. No abstract available.

PMID:
12481721
42.

Divergence between samples of chimpanzee and human DNA sequences is 5%, counting indels.

Britten RJ.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13633-5. Epub 2002 Oct 4.

43.

Response of base excision repair enzymes to complex DNA lesions.

Weinfeld M, Rasouli-Nia A, Chaudhry MA, Britten RA.

Radiat Res. 2001 Nov;156(5 Pt 2):584-9. Review.

PMID:
11604076
44.

Inactivation of wild-type p53 by a dominant negative mutant renders MCF-7 cells resistant to tubulin-binding agent cytotoxicity.

Galmarini CM, Falette N, Tabone E, Levrat C, Britten R, Voorzanger-Rousselot N, Roesch-Gateau O, Vanier-Viornery A, Puisieux A, Dumontet C.

Br J Cancer. 2001 Sep 14;85(6):902-8.

45.

Biological factors influencing the RBE of neutrons: implications for their past, present and future use in radiotherapy.

Britten RA, Peters LJ, Murray D.

Radiat Res. 2001 Aug;156(2):125-35. Review.

PMID:
11448233
46.

Identification of new skeletogenic genes of the sea urchin embryo by use of conserved sequence motifs among the SM50 gene family.

Lee YH, Kwak J, Britten RJ, Davidson EH.

Zygote. 2000;8 Suppl 1:S74. No abstract available.

PMID:
11191327
47.

ERCC1 expression as a molecular marker of cisplatin resistance in human cervical tumor cells.

Britten RA, Liu D, Tessier A, Hutchison MJ, Murray D.

Int J Cancer. 2000 Sep 20;89(5):453-7.

48.

Differential impact of Raf-1 kinase activity on tumor cell resistance to paclitaxel and docetaxel.

Britten RA, Klein K.

Anticancer Drugs. 2000 Jul;11(6):439-43.

PMID:
11001384
49.

A sea urchin genome project: sequence scan, virtual map, and additional resources.

Cameron RA, Mahairas G, Rast JP, Martinez P, Biondi TR, Swartzell S, Wallace JC, Poustka AJ, Livingston BT, Wray GA, Ettensohn CA, Lehrach H, Britten RJ, Davidson EH, Hood L.

Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9514-8.

50.

The influence of hypoxia on the relative sensitivity of human tumor cells to 62.5 MeV (p-->Be) fast neutrons and 4 MeV photons.

Warenius HM, White R, Peacock JH, Hanson J, Britten RA, Murray D.

Radiat Res. 2000 Jul;154(1):54-63.

PMID:
10856966

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