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Items: 42


A Novel Assessment Tool for Impulsive Aggression in Children with Attention-Deficit/Hyperactivity Disorder.

Ceresoli-Borroni G, Liranso T, Brittain ST, Connor DF, Evans CJ, Findling RL, Hwang S, Candler SA, Robb AS, Nasser A, Schwabe S.

J Child Adolesc Psychopharmacol. 2019 Aug 2. doi: 10.1089/cap.2019.0035. [Epub ahead of print]


Application of the Impulsive Aggression Diary in Adolescents with Attention-Deficit/Hyperactivity Disorder.

Ceresoli-Borroni G, Liranso T, Brittain ST, Connor DF, Evans CJ, Findling RL, Hwang S, Fry N, Candler SA, Robb AS, Saylor K, Nasser A, Schwabe S.

J Child Adolesc Psychopharmacol. 2019 Jul 25. doi: 10.1089/cap.2018.0089. [Epub ahead of print]


Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.

Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK.

Nat Chem Biol. 2019 Jul;15(7):747-755. doi: 10.1038/s41589-019-0304-8. Epub 2019 Jun 17.


Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.

Ward CC, Kleinman JI, Brittain SM, Lee PS, Chung CYS, Kim K, Petri Y, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Nomura DK.

ACS Chem Biol. 2019 May 13. doi: 10.1021/acschembio.8b01083. [Epub ahead of print]


Conservation publications and their provisions to protect research participants.

Ibbett H, Brittain S.

Conserv Biol. 2019 Apr 23. doi: 10.1111/cobi.13337. [Epub ahead of print] Review.


Discovery of a ZIP7 inhibitor from a Notch pathway screen.

Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, Lindeman A, Sigoillot F, Chen A, Xie KX, Ho S, Reece-Hoyes J, Weihofen WA, Tyskiewicz K, Hoepfner D, McDonald RI, Guthrie N, Dogra A, Guo H, Shao J, Ding J, Canham SM, Boynton G, George EL, Kang ZB, Antczak C, Porter JA, Wallace O, Tallarico JA, Palmer AE, Jenkins JL, Jain RK, Bushell SM, Fryer CJ.

Nat Chem Biol. 2019 Feb;15(2):179-188. doi: 10.1038/s41589-018-0200-7. Epub 2019 Jan 14.


Previously Uncharacterized Vacuolar-type ATPase Binding Site Discovered from Structurally Similar Compounds with Distinct Mechanisms of Action.

Wang AC, Pham HT, Lipps JM, Brittain SM, Harrington E, Wang Y, King FJ, Russ C, Pan X, Hoepfner D, Tallarico J, Feng Y, Jain RK, Schirle M, Thomas JR.

ACS Chem Biol. 2019 Jan 18;14(1):20-26. doi: 10.1021/acschembio.8b00656. Epub 2018 Dec 18.


A Photoaffinity Labeling-Based Chemoproteomics Strategy for Unbiased Target Deconvolution of Small Molecule Drug Candidates.

Thomas JR, Brittain SM, Lipps J, Llamas L, Jain RK, Schirle M.

Methods Mol Biol. 2017;1647:1-18. doi: 10.1007/978-1-4939-7201-2_1.


Use of computer simulations to test the concept of dose forgiveness in the era of extended-release (XR) drugs.

Pellock JM, Brittain ST.

Epilepsy Behav. 2016 Feb;55:21-3. doi: 10.1016/j.yebeh.2015.11.029. Epub 2015 Dec 24.


Pharmacokinetic simulations of topiramate plasma concentrations following dosing irregularities with extended-release vs. immediate-release formulations.

Brittain ST, Wheless JW.

Epilepsy Behav. 2015 Nov;52(Pt A):31-6. doi: 10.1016/j.yebeh.2015.08.029. Epub 2015 Sep 24.


Long-term efficacy and safety of adjunctive extended-release oxcarbazepine (Oxtellar XR® ) in adults with partial-onset seizures.

Chung SS, Johnson JK, Brittain ST, Baroldi P.

Acta Neurol Scand. 2016 Feb;133(2):124-130. doi: 10.1111/ane.12467. Epub 2015 Aug 6.


Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.

Griebel G, Pichat P, Beeské S, Leroy T, Redon N, Jacquet A, Françon D, Bert L, Even L, Lopez-Grancha M, Tolstykh T, Sun F, Yu Q, Brittain S, Arlt H, He T, Zhang B, Wiederschain D, Bertrand T, Houtmann J, Rak A, Vallée F, Michot N, Augé F, Menet V, Bergis OE, George P, Avenet P, Mikol V, Didier M, Escoubet J.

Sci Rep. 2015 Jan 6;5:7642. doi: 10.1038/srep07642.


Statins as bioactive molecules to support bone regeneration.

Brittain SB, Gohil SV, Nair LS.

Curr Med Chem. 2014;21(25):2980-8.


Efficacy and safety of extended-release oxcarbazepine (Oxtellar XR™) as adjunctive therapy in patients with refractory partial-onset seizures: a randomized controlled trial.

French JA, Baroldi P, Brittain ST, Johnson JK; PROSPER Investigators Study Group.

Acta Neurol Scand. 2014 Mar;129(3):143-53. doi: 10.1111/ane.12207. Epub 2013 Dec 21.


Recovery of sulfate saturated soils in the Plynlimon catchments, mid-Wales following reductions in atmospheric S inputs from the 1980s to 2011.

Hughes S, Reynolds B, Norris DA, Brittain SA, Dere AL, Woods C, Armstrong LK, Harman SA, Wickham HD.

J Environ Monit. 2012 May;14(6):1531-41. doi: 10.1039/c2em30070b. Epub 2012 Apr 20.


Chemical speciation studies on DU contaminated soils using flow field flow fractionation linked to inductively coupled plasma mass spectrometry (FlFFF-ICP-MS).

Brittain SR, Cox AG, Tomos AD, Paterson E, Siripinyanond A, McLeod CW.

J Environ Monit. 2012 Mar;14(3):782-90. doi: 10.1039/c2em10716c. Epub 2012 Jan 11.


Kinase inhibitor profiling using chemoproteomics.

Schirle M, Petrella EC, Brittain SM, Schwalb D, Harrington E, Cornella-Taracido I, Tallarico JA.

Methods Mol Biol. 2012;795:161-77. doi: 10.1007/978-1-61779-337-0_11.


Remembering a wonderful matron and friend to many.

Brittain S.

Nurs Stand. 2011 Jul 27;25(47):33. doi: 10.7748/ns.25.47.33.s46.


Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.

Han GW, Yang XL, McMullan D, Chong YE, Krishna SS, Rife CL, Weekes D, Brittain SM, Abdubek P, Ambing E, Astakhova T, Axelrod HL, Carlton D, Caruthers J, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grant JC, Grzechnik SK, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kumar A, Marciano D, Miller MD, Morse AT, Nigoghossian E, Okach L, Paulsen J, Reyes R, van den Bedem H, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Elsliger MA, Schimmel P, Wilson IA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Oct 1;66(Pt 10):1326-34. doi: 10.1107/S1744309110037619. Epub 2010 Sep 23.


In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.

Cellitti SE, Jones DH, Lagpacan L, Hao X, Zhang Q, Hu H, Brittain SM, Brinker A, Caldwell J, Bursulaya B, Spraggon G, Brock A, Ryu Y, Uno T, Schultz PG, Geierstanger BH.

J Am Chem Soc. 2008 Jul 23;130(29):9268-81. doi: 10.1021/ja801602q. Epub 2008 Jun 25.


Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution.

Xu Q, Kozbial P, McMullan D, Krishna SS, Brittain SM, Ficarro SB, DiDonato M, Miller MD, Abdubek P, Axelrod HL, Chiu HJ, Clayton T, Duan L, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Han GW, Jaroszewski L, Klock HE, Morse AT, Nigoghossian E, Paulsen J, Reyes R, Rife CL, van den Bedem H, White A, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA.

Proteins. 2008 May 15;71(3):1546-52. doi: 10.1002/prot.21992. No abstract available.


Control of protein phosphorylation with a genetically encoded photocaged amino acid.

Lemke EA, Summerer D, Geierstanger BH, Brittain SM, Schultz PG.

Nat Chem Biol. 2007 Dec;3(12):769-72. Epub 2007 Oct 28.


Selective metabolite and peptide capture/mass detection using fluorous affinity tags.

Go EP, Uritboonthai W, Apon JV, Trauger SA, Nordstrom A, O'Maille G, Brittain SM, Peters EC, Siuzdak G.

J Proteome Res. 2007 Apr;6(4):1492-9. Epub 2007 Mar 8.


Complex hydrological controls on wet dune slacks: the importance of local variability.

Jones ML, Reynolds B, Brittain SA, Norris DA, Rhind PM, Jones RE.

Sci Total Environ. 2006 Dec 15;372(1):266-77. Epub 2006 Oct 24.


Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site.

DiDonato M, Krishna SS, Schwarzenbacher R, McMullan D, Agarwalla S, Brittain SM, Miller MD, Abdubek P, Ambing E, Axelrod HL, Canaves JM, Chiu HJ, Deacon AM, Duan L, Elsliger MA, Godzik A, Grzechnik SK, Hale J, Hampton E, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Koesema E, Kreusch A, Kuhn P, Lesley SA, Levin I, Morse AT, Nigoghossian E, Okach L, Oommachen S, Paulsen J, Quijano K, Reyes R, Rife CL, Spraggon G, Stevens RC, van den Bedem H, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA.

Proteins. 2006 Nov 15;65(3):771-6. No abstract available.


Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution.

Han GW, Sri Krishna S, Schwarzenbacher R, McMullan D, Ginalski K, Elsliger MA, Brittain SM, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod H, Canaves JM, Chiu HJ, DiDonato M, Grzechnik SK, Hale J, Hampton E, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Koesema E, Kreusch A, Kuhn P, Miller MD, Morse AT, Moy K, Nigoghossian E, Oommachen S, Ouyang J, Paulsen J, Quijano K, Reyes R, Rife C, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Wang X, West B, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA.

Proteins. 2006 Sep 1;64(4):1083-90. No abstract available.


Efficient delivery of RNA interference effectors via in vitro-packaged SV40 pseudovirions.

Kimchi-Sarfaty C, Brittain S, Garfield S, Caplen NJ, Tang Q, Gottesman MM.

Hum Gene Ther. 2005 Sep;16(9):1110-5.


Enrichment and analysis of peptide subsets using fluorous affinity tags and mass spectrometry.

Brittain SM, Ficarro SB, Brock A, Peters EC.

Nat Biotechnol. 2005 Apr;23(4):463-8. Epub 2005 Mar 13.


Effects of increased deposition of atmospheric nitrogen on an upland moor: leaching of N species and soil solution chemistry.

Pilkington MG, Caporn SJ, Carroll JA, Cresswell N, Lee JA, Ashenden TW, Brittain SA, Reynolds B, Emmett BA.

Environ Pollut. 2005 May;135(1):29-40.


Changes in vegetation and soil characteristics in coastal sand dunes along a gradient of atmospheric nitrogen deposition.

Jones ML, Wallace HL, Norris D, Brittain SA, Haria S, Jones RE, Rhind PM, Reynolds BR, Emmett BA.

Plant Biol (Stuttg). 2004 Sep;6(5):598-605.


Transduction of multiple cell types using improved conditions for gene delivery and expression of SV40 pseudovirions packaged in vitro.

Kimchi-Sarfaty C, Alexander NS, Brittain S, Ali S, Gottesman MM.

Biotechniques. 2004 Aug;37(2):270-5.


[ADMAdda5]-microcystins in Planktothrix agardhii strain PH-123 (cyanobacteria)--importance for monitoring of microcystins in the environment.

Laub J, Henriksen P, Brittain SM, Wang J, Carmichael WW, Rinehart KL, Moestrup O.

Environ Toxicol. 2002;17(4):351-7.


CO and H(3)(+) in the protoplanetary disk around the star HD141569.

Brittain SD, Rettig TW.

Nature. 2002 Jul 4;418(6893):57-9.


Organic composition of C/1999 S4 (LINEAR): a comet formed near Jupiter?

Mumma MJ, Dello Russo N, DiSanti MA, Magee-Sauer K, Novak RE, Brittain S, Rettig T, McLean IS, Reuter DC, Xu LH.

Science. 2001 May 18;292(5520):1334-9.


Isolation and identification of the cyanotoxin cylindrospermopsin and deoxy-cylindrospermopsin from a Thailand strain of Cylindrospermopsis raciborskii (Cyanobacteria).

Li R, Carmichael WW, Brittain S, Eaglesham GK, Shaw GR, Mahakhant A, Noparatnaraporn N, Yongmanitchai W, Kaya K, Watanabe MM.

Toxicon. 2001 Jul;39(7):973-80.


[D-Leu(1)] microcystin-LR, a new microcystin isoplated from waterbloom in a Canadian prairie lake.

Park H, Namikoshi M, Brittain SM, Carmichael WW, Murphy T.

Toxicon. 2001 Jun;39(6):855-62.


Prototyping of masks, masters, and stamps/molds for soft lithography using an office printer and photographic reduction

Deng T, Wu H, Brittain ST, Whitesides GM.

Anal Chem. 2000 Jul 15;72(14):3176-80.


Isolation and characterization of microcystins from a river nile strain of Oscillatoria tenuis Agardh ex Gomont.

Brittain S, Mohamed ZA, Wang J, Lehmann VK, Carmichael WW, Rinehart KL.

Toxicon. 2000 Dec;38(12):1759-71.


Modeling the kinetics of acylation of insulin using a recursive method for solving the systems of coupled differential equations.

Grzybowski BA, Anderson JR, Colton I, Brittain ST, Shakhnovich EI, Whitesides GM.

Biophys J. 2000 Feb;78(2):652-61.


Design and fabrication of topologically complex, three-dimensional microstructures

Jackman RJ, Brittain ST, Adams A, Prentiss MG, Whitesides GM.

Science. 1998 Jun 26;280(5372):2089-91.


Seven new microcystins possessing two L-glutamic acid units, isolated from Anabaena sp. strain 186.

Namikoshi M, Yuan M, Sivonen K, Carmichael WW, Rinehart KL, Rouhiainen L, Sun F, Brittain S, Otsuki A.

Chem Res Toxicol. 1998 Feb;11(2):143-9.


A piper's warning.

Hartenstein RW, Brittain SM.

Arch Otolaryngol Head Neck Surg. 1988 Jun;114(6):682. No abstract available.


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