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Items: 1 to 50 of 185

1.

Contribution of congenital cytomegalovirus (cCMV) to permanent hearing loss in a highly seropositive population: "The BraCHS study".

Yamamoto AY, Anastasio ART, Massuda ET, Isaac ML, Manfredi AKS, Cavalcante JMS, Carnevale-Silva A, Fowler KB, Boppana S, Britt WJ, Mussi-Pinhata MM.

Clin Infect Dis. 2019 May 17. pii: ciz413. doi: 10.1093/cid/ciz413. [Epub ahead of print]

PMID:
31102409
2.

CD4 T cells are required for maintenance of CD8 TRM cells and virus control in the brain of MCMV-infected newborn mice.

Brizić I, Hiršl L, Šustić M, Golemac M, Britt WJ, Krmpotić A, Jonjić S.

Med Microbiol Immunol. 2019 Aug;208(3-4):487-494. doi: 10.1007/s00430-019-00601-0. Epub 2019 Mar 28.

PMID:
30923899
3.

Role of antibodies in confining cytomegalovirus after reactivation from latency: three decades' résumé.

Krmpotić A, Podlech J, Reddehase MJ, Britt WJ, Jonjić S.

Med Microbiol Immunol. 2019 Aug;208(3-4):415-429. doi: 10.1007/s00430-019-00600-1. Epub 2019 Mar 28. Review.

PMID:
30923898
4.

HCMV trimer- and pentamer-specific antibodies synergize for virus neutralization but do not correlate with congenital transmission.

Vanarsdall AL, Chin AL, Liu J, Jardetzky TS, Mudd JO, Orloff SL, Streblow D, Mussi-Pinhata MM, Yamamoto AY, Duarte G, Britt WJ, Johnson DC.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3728-3733. doi: 10.1073/pnas.1814835116. Epub 2019 Feb 7.

5.

New therapies for human cytomegalovirus infections.

Britt WJ, Prichard MN.

Antiviral Res. 2018 Nov;159:153-174. doi: 10.1016/j.antiviral.2018.09.003. Epub 2018 Sep 15. Review.

PMID:
30227153
6.

Maternal Immunity and the Natural History of Congenital Human Cytomegalovirus Infection.

Britt WJ.

Viruses. 2018 Aug 3;10(8). pii: E405. doi: 10.3390/v10080405. Review.

7.

Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7.

Dennis EA, Smythies LE, Grabski R, Li M, Ballestas ME, Shimamura M, Sun JJ, Grams J, Stahl R, Niederweis ME, Britt WJ, Smith PD.

Mucosal Immunol. 2018 Nov;11(6):1694-1704. doi: 10.1038/s41385-018-0041-4. Epub 2018 Aug 3.

PMID:
30076393
8.

Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus.

Wu CC, Jiang X, Wang XZ, Liu XJ, Li XJ, Yang B, Ye HQ, Harwardt T, Jiang M, Xia HM, Wang W, Britt WJ, Paulus C, Nevels M, Luo MH.

J Virol. 2018 Aug 16;92(17). pii: e00340-18. doi: 10.1128/JVI.00340-18. Print 2018 Sep 1.

9.

Seroconversion for Cytomegalovirus Infection During Pregnancy and Fetal Infection in a Highly Seropositive Population: "The BraCHS Study".

Mussi-Pinhata MM, Yamamoto AY, Aragon DC, Duarte G, Fowler KB, Boppana S, Britt WJ.

J Infect Dis. 2018 Sep 8;218(8):1200-1204. doi: 10.1093/infdis/jiy321.

10.

Adverse outcomes of pregnancy-associated Zika virus infection.

Britt WJ.

Semin Perinatol. 2018 Apr;42(3):155-167. doi: 10.1053/j.semperi.2018.02.003. Epub 2018 Mar 6. Review.

PMID:
29523447
11.

Brain-resident memory CD8+ T cells induced by congenital CMV infection prevent brain pathology and virus reactivation.

Brizić I, Šušak B, Arapović M, Huszthy PC, Hiršl L, Kveštak D, Juranić Lisnić V, Golemac M, Pernjak Pugel E, Tomac J, Oxenius A, Britt WJ, Arapović J, Krmpotić A, Jonjić S.

Eur J Immunol. 2018 Jun;48(6):950-964. doi: 10.1002/eji.201847526. Epub 2018 Mar 23.

12.

Cytomegalovirus Shedding in Seropositive Pregnant Women From a High-Seroprevalence Population: The Brazilian Cytomegalovirus Hearing and Maternal Secondary Infection Study.

Barbosa NG, Yamamoto AY, Duarte G, Aragon DC, Fowler KB, Boppana S, Britt WJ, Mussi-Pinhata MM.

Clin Infect Dis. 2018 Aug 16;67(5):743-750. doi: 10.1093/cid/ciy166.

13.

WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress.

Yang B, Liu XJ, Yao Y, Jiang X, Wang XZ, Yang H, Sun JY, Miao Y, Wang W, Huang ZL, Wang Y, Tang Q, Rayner S, Britt WJ, McVoy MA, Luo MH, Zhao F.

J Virol. 2018 Apr 13;92(9). pii: e00207-18. doi: 10.1128/JVI.00207-18. Print 2018 May 1.

14.

Human Cytomegalovirus Nuclear Capsids Associate with the Core Nuclear Egress Complex and the Viral Protein Kinase pUL97.

Milbradt J, Sonntag E, Wagner S, Strojan H, Wangen C, Lenac Rovis T, Lisnic B, Jonjic S, Sticht H, Britt WJ, Schlötzer-Schrehardt U, Marschall M.

Viruses. 2018 Jan 13;10(1). pii: E35. doi: 10.3390/v10010035.

15.

Immune responses to congenital cytomegalovirus infection.

Brizić I, Hiršl L, Britt WJ, Krmpotić A, Jonjić S.

Microbes Infect. 2018 Oct - Nov;20(9-10):543-551. doi: 10.1016/j.micinf.2017.12.010. Epub 2017 Dec 26. Review.

PMID:
29287989
16.

Herpesviridae Infection: Prevention, Screening, and Management.

Subramaniam A, Britt WJ.

Clin Obstet Gynecol. 2018 Mar;61(1):157-176. doi: 10.1097/GRF.0000000000000335. Review.

PMID:
29283902
17.

Pathogenesis of Non-Zika Congenital Viral Infections.

Boppana SB, Britt WJ, Fowler K, Hutto SC, James SH, Kimberlin DW, Poole C, Ross SA, Whitley RJ.

J Infect Dis. 2017 Dec 16;216(suppl_10):S912-S918. doi: 10.1093/infdis/jix431. Review.

18.

Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus.

Bootz A, Karbach A, Spindler J, Kropff B, Reuter N, Sticht H, Winkler TH, Britt WJ, Mach M.

PLoS Pathog. 2017 Aug 30;13(8):e1006601. doi: 10.1371/journal.ppat.1006601. eCollection 2017 Aug.

19.

Human cytomegalovirus IE1 downregulates Hes1 in neural progenitor cells as a potential E3 ubiquitin ligase.

Liu XJ, Yang B, Huang SN, Wu CC, Li XJ, Cheng S, Jiang X, Hu F, Ming YZ, Nevels M, Britt WJ, Rayner S, Tang Q, Zeng WB, Zhao F, Luo MH.

PLoS Pathog. 2017 Jul 27;13(7):e1006542. doi: 10.1371/journal.ppat.1006542. eCollection 2017 Jul.

20.

Cytomegalovirus vector expressing RAE-1γ induces enhanced anti-tumor capacity of murine CD8+ T cells.

Tršan T, Vuković K, Filipović P, Brizić AL, Lemmermann NAW, Schober K, Busch DH, Britt WJ, Messerle M, Krmpotić A, Jonjić S.

Eur J Immunol. 2017 Aug;47(8):1354-1367. doi: 10.1002/eji.201746964. Epub 2017 Jul 4.

21.

Congenital Human Cytomegalovirus Infection and the Enigma of Maternal Immunity.

Britt WJ.

J Virol. 2017 Jul 12;91(15). pii: e02392-16. doi: 10.1128/JVI.02392-16. Print 2017 Aug 1. Review.

22.

Tumor Necrosis Factor Alpha-Induced Recruitment of Inflammatory Mononuclear Cells Leads to Inflammation and Altered Brain Development in Murine Cytomegalovirus-Infected Newborn Mice.

Seleme MC, Kosmac K, Jonjic S, Britt WJ.

J Virol. 2017 Mar 29;91(8). pii: e01983-16. doi: 10.1128/JVI.01983-16. Print 2017 Apr 15.

23.

Characterizing human cytomegalovirus reinfection in congenitally infected infants: an evolutionary perspective.

Pokalyuk C, Renzette N, Irwin KK, Pfeifer SP, Gibson L, Britt WJ, Yamamoto AY, Mussi-Pinhata MM, Kowalik TF, Jensen JD.

Mol Ecol. 2017 Apr;26(7):1980-1990. doi: 10.1111/mec.13953. Epub 2017 Feb 8.

PMID:
27988973
24.

Human cytomegalovirus phosphoproteins are hypophosphorylated and intrinsically disordered.

Rieder FJJ, Kastner MT, Hartl M, Puchinger MG, Schneider M, Majdic O, Britt WJ, Djinović-Carugo K, Steininger C.

J Gen Virol. 2017 Mar;98(3):471-485. doi: 10.1099/jgv.0.000675. Epub 2017 Apr 1.

25.

Correction for Pan et al., Later Passages of Neural Progenitor Cells from Neonatal Brain Are More Permissive for Human Cytomegalovirus Infection.

Pan X, Li XJ, Liu XJ, Yuan H, Li JF, Duan YL, Ye HQ, Fu YR, Qiao GH, Wu CC, Yang B, Tian XH, Hu KH, Miao LF, Chen XL, Zheng J, Rayner S, Schwartz PH, Britt WJ, Xu J, Luo MH.

J Virol. 2016 Oct 28;90(22):10431-10433. doi: 10.1128/JVI.01780-16. Print 2016 Nov 15. No abstract available.

26.
27.

Microbial Cryptotopes are Prominent Targets of B-cell Immunity.

Rieder FJ, Biebl J, Kastner MT, Schneider M, Jungbauer C, Redlberger-Fritz M, Britt WJ, Kundi M, Steininger C.

Sci Rep. 2016 Aug 19;6:31657. doi: 10.1038/srep31657.

28.

Distinct functional domains within the acidic cluster of tegument protein pp28 required for trafficking and cytoplasmic envelopment of human cytomegalovirus.

Seo JY, Jeon H, Hong S, Britt WJ.

J Gen Virol. 2016 Oct;97(10):2677-2683. doi: 10.1099/jgv.0.000565. Epub 2016 Jul 22.

29.

Clinical Predictors of Sensorineural Hearing Loss and Cognitive Outcome in Infants with Symptomatic Congenital Cytomegalovirus Infection.

Pinninti SG, Rodgers MD, Novak Z, Britt WJ, Fowler KB, Boppana SB, Ross SA.

Pediatr Infect Dis J. 2016 Aug;35(8):924-6. doi: 10.1097/INF.0000000000001194.

30.

Vaccine-Derived Neutralizing Antibodies to the Human Cytomegalovirus gH/gL Pentamer Potently Block Primary Cytotrophoblast Infection.

Chiuppesi F, Wussow F, Johnson E, Bian C, Zhuo M, Rajakumar A, Barry PA, Britt WJ, Chakraborty R, Diamond DJ.

J Virol. 2015 Dec;89(23):11884-98. doi: 10.1128/JVI.01701-15. Epub 2015 Sep 16.

31.

Limits and patterns of cytomegalovirus genomic diversity in humans.

Renzette N, Pokalyuk C, Gibson L, Bhattacharjee B, Schleiss MR, Hamprecht K, Yamamoto AY, Mussi-Pinhata MM, Britt WJ, Jensen JD, Kowalik TF.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4120-8. doi: 10.1073/pnas.1501880112. Epub 2015 Jul 6.

32.

Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neural Progenitor Cells.

Li XJ, Liu XJ, Yang B, Fu YR, Zhao F, Shen ZZ, Miao LF, Rayner S, Chavanas S, Zhu H, Britt WJ, Tang Q, McVoy MA, Luo MH.

J Virol. 2015 Jul;89(13):6792-804. doi: 10.1128/JVI.00351-15. Epub 2015 Apr 22.

33.

Murine CMV-induced hearing loss is associated with inner ear inflammation and loss of spiral ganglia neurons.

Bradford RD, Yoo YG, Golemac M, Pugel EP, Jonjic S, Britt WJ.

PLoS Pathog. 2015 Apr 13;11(4):e1004774. doi: 10.1371/journal.ppat.1004774. eCollection 2015 Apr.

34.

A viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism.

Li G, Nguyen CC, Ryckman BJ, Britt WJ, Kamil JP.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4471-6. doi: 10.1073/pnas.1419875112. Epub 2015 Mar 23.

35.

MicroRNA miR-21 attenuates human cytomegalovirus replication in neural cells by targeting Cdc25a.

Fu YR, Liu XJ, Li XJ, Shen ZZ, Yang B, Wu CC, Li JF, Miao LF, Ye HQ, Qiao GH, Rayner S, Chavanas S, Davrinche C, Britt WJ, Tang Q, McVoy M, Mocarski E, Luo MH.

J Virol. 2015 Jan 15;89(2):1070-82. doi: 10.1128/JVI.01740-14. Epub 2014 Nov 5.

36.

Cytomegalovirus enhances macrophage TLR expression and MyD88-mediated signal transduction to potentiate inducible inflammatory responses.

Smith PD, Shimamura M, Musgrove LC, Dennis EA, Bimczok D, Novak L, Ballestas M, Fenton A, Dandekar S, Britt WJ, Smythies LE.

J Immunol. 2014 Dec 1;193(11):5604-12. doi: 10.4049/jimmunol.1302608. Epub 2014 Oct 29.

37.

Identification of a neutralizing epitope within antigenic domain 5 of glycoprotein B of human cytomegalovirus.

Wiegers AK, Sticht H, Winkler TH, Britt WJ, Mach M.

J Virol. 2015 Jan;89(1):361-72. doi: 10.1128/JVI.02393-14. Epub 2014 Oct 15.

38.

Immunobiology of congenital cytomegalovirus infection of the central nervous system—the murine cytomegalovirus model.

Slavuljica I, Kveštak D, Huszthy PC, Kosmac K, Britt WJ, Jonjić S.

Cell Mol Immunol. 2015 Mar;12(2):180-91. doi: 10.1038/cmi.2014.51. Epub 2014 Jul 21. Review.

39.

Low antibody-dependent cellular cytotoxicity responses in Zambians prior to HIV-1 intrasubtype C superinfection.

Basu D, Xiao P, Ende Z, Bere A, Britt WJ, Mulenga J, Kilembe W, Allen SA, Derdeyn CA, Hunter E.

Virology. 2014 Aug;462-463:295-8. doi: 10.1016/j.virol.2014.06.016. Epub 2014 Jul 5.

40.

Recent approaches and strategies in the generation of antihuman cytomegalovirus vaccines.

Boppana SB, Britt WJ.

Methods Mol Biol. 2014;1119:311-48. doi: 10.1007/978-1-62703-788-4_17.

PMID:
24639230
41.

Spectrum of disease and outcome in children with symptomatic congenital cytomegalovirus infection.

Dreher AM, Arora N, Fowler KB, Novak Z, Britt WJ, Boppana SB, Ross SA.

J Pediatr. 2014 Apr;164(4):855-9. doi: 10.1016/j.jpeds.2013.12.007. Epub 2014 Jan 14.

42.

The smallest capsid protein mediates binding of the essential tegument protein pp150 to stabilize DNA-containing capsids in human cytomegalovirus.

Dai X, Yu X, Gong H, Jiang X, Abenes G, Liu H, Shivakoti S, Britt WJ, Zhu H, Liu F, Zhou ZH.

PLoS Pathog. 2013 Aug;9(8):e1003525. doi: 10.1371/journal.ppat.1003525. Epub 2013 Aug 15.

43.

Later passages of neural progenitor cells from neonatal brain are more permissive for human cytomegalovirus infection.

Pan X, Li XJ, Liu XJ, Yuan H, Li JF, Duan YL, Ye HQ, Fu YR, Qiao GH, Wu CC, Yang B, Tian XH, Hu KH, Miao LF, Chen XL, Zheng J, Rayner S, Schwartz PH, Britt WJ, Xu J, Luo MH.

J Virol. 2013 Oct;87(20):10968-79. doi: 10.1128/JVI.01120-13. Epub 2013 Jul 31. Erratum in: J Virol. 2016 Oct 28;90(22):10431-10433.

44.

Glucocorticoid treatment of MCMV infected newborn mice attenuates CNS inflammation and limits deficits in cerebellar development.

Kosmac K, Bantug GR, Pugel EP, Cekinovic D, Jonjic S, Britt WJ.

PLoS Pathog. 2013 Mar;9(3):e1003200. doi: 10.1371/journal.ppat.1003200. Epub 2013 Mar 7.

45.

Ganciclovir prophylaxis improves late murine cytomegalovirus-induced renal allograft damage.

Shimamura M, Seleme MC, Guo L, Saunders U, Schoeb TR, George JF, Britt WJ.

Transplantation. 2013 Jan 15;95(1):48-53. doi: 10.1097/TP.0b013e3182782efc.

46.

Strain-specific neutralizing antibody responses against human cytomegalovirus envelope glycoprotein N.

Pati SK, Novak Z, Purser M, Arora N, Mach M, Britt WJ, Boppana SB.

Clin Vaccine Immunol. 2012 Jun;19(6):909-13. doi: 10.1128/CVI.00092-12. Epub 2012 Apr 4.

47.

Mixed infection and strain diversity in congenital cytomegalovirus infection.

Ross SA, Novak Z, Pati S, Patro RK, Blumenthal J, Danthuluri VR, Ahmed A, Michaels MG, Sánchez PJ, Bernstein DI, Tolan RW, Palmer AL, Britt WJ, Fowler KB, Boppana SB.

J Infect Dis. 2011 Oct 1;204(7):1003-7. doi: 10.1093/infdis/jir457.

48.

Ganciclovir transiently attenuates murine cytomegalovirus-associated renal allograft inflammation.

Shimamura M, Saunders U, Rha B, Guo L, Cassady KA, George JF, Britt WJ.

Transplantation. 2011 Oct 15;92(7):759-66. doi: 10.1097/TP.0b013e31822c6e89.

49.

Congenital cytomegalovirus infection as a cause of sensorineural hearing loss in a highly immune population.

Yamamoto AY, Mussi-Pinhata MM, Isaac Mde L, Amaral FR, Carvalheiro CG, Aragon DC, Manfredi AK, Boppana SB, Britt WJ.

Pediatr Infect Dis J. 2011 Dec;30(12):1043-6. doi: 10.1097/INF.0b013e31822d9640.

50.

Saliva polymerase-chain-reaction assay for cytomegalovirus screening in newborns.

Boppana SB, Ross SA, Shimamura M, Palmer AL, Ahmed A, Michaels MG, Sánchez PJ, Bernstein DI, Tolan RW Jr, Novak Z, Chowdhury N, Britt WJ, Fowler KB; National Institute on Deafness and Other Communication Disorders CHIMES Study.

N Engl J Med. 2011 Jun 2;364(22):2111-8. doi: 10.1056/NEJMoa1006561.

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