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Items: 45

1.

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes.

Shahmoradian SH, Lewis AJ, Genoud C, Hench J, Moors TE, Navarro PP, Castaño-Díez D, Schweighauser G, Graff-Meyer A, Goldie KN, Sütterlin R, Huisman E, Ingrassia A, Gier Y, Rozemuller AJM, Wang J, Paepe A, Erny J, Staempfli A, Hoernschemeyer J, Großerüschkamp F, Niedieker D, El-Mashtoly SF, Quadri M, Van IJcken WFJ, Bonifati V, Gerwert K, Bohrmann B, Frank S, Britschgi M, Stahlberg H, Van de Berg WDJ, Lauer ME.

Nat Neurosci. 2019 Jul;22(7):1099-1109. doi: 10.1038/s41593-019-0423-2. Epub 2019 Jun 24.

PMID:
31235907
2.

Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles.

Navarro PP, Genoud C, Castaño-Díez D, Graff-Meyer A, Lewis AJ, de Gier Y, Lauer ME, Britschgi M, Bohrmann B, Frank S, Hench J, Schweighauser G, Rozemuller AJM, van de Berg WDJ, Stahlberg H, Shahmoradian SH.

Sci Rep. 2018 Dec 21;8(1):18046. doi: 10.1038/s41598-018-36223-4.

3.

Cryo-EM structure of alpha-synuclein fibrils.

Guerrero-Ferreira R, Taylor NM, Mona D, Ringler P, Lauer ME, Riek R, Britschgi M, Stahlberg H.

Elife. 2018 Jul 3;7. pii: e36402. doi: 10.7554/eLife.36402.

4.

Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells.

Schaeuble K, Britschgi MR, Scarpellino L, Favre S, Xu Y, Koroleva E, Lissandrin TKA, Link A, Matloubian M, Ware CF, Nedospasov SA, Tumanov AV, Cyster JG, Luther SA.

Cell Rep. 2017 Nov 28;21(9):2500-2514. doi: 10.1016/j.celrep.2017.10.119.

5.

Three-Dimensional Imaging of Biological Tissue by Cryo X-Ray Ptychography.

Shahmoradian SH, Tsai EHR, Diaz A, Guizar-Sicairos M, Raabe J, Spycher L, Britschgi M, Ruf A, Stahlberg H, Holler M.

Sci Rep. 2017 Jul 24;7(1):6291. doi: 10.1038/s41598-017-05587-4.

6.

Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.

Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, Wyss-Coray T.

J Exp Med. 2017 Apr 3;214(4):1081-1092. doi: 10.1084/jem.20162011. Epub 2017 Mar 15.

7.

Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain.

Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hofree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T.

Mol Neurodegener. 2016 May 23;11(1):42. No abstract available.

8.

Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain.

Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hofree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T.

Mol Neurodegener. 2016 Apr 26;11:31. doi: 10.1186/s13024-016-0095-2. Erratum in: Mol Neurodegener. 2016;11(1):42.

9.

Combined Plasma and Cerebrospinal Fluid Signature for the Prediction of Midterm Progression From Mild Cognitive Impairment to Alzheimer Disease.

Lehallier B, Essioux L, Gayan J, Alexandridis R, Nikolcheva T, Wyss-Coray T, Britschgi M; Alzheimer’s Disease Neuroimaging Initiative.

JAMA Neurol. 2016 Feb;73(2):203-212. doi: 10.1001/jamaneurol.2015.3135. Epub 2015 Dec 14.

10.

Maternal immune activation and abnormal brain development across CNS disorders.

Knuesel I, Chicha L, Britschgi M, Schobel SA, Bodmer M, Hellings JA, Toovey S, Prinssen EP.

Nat Rev Neurol. 2014 Nov;10(11):643-60. doi: 10.1038/nrneurol.2014.187. Epub 2014 Oct 14. Review.

PMID:
25311587
11.

Mind the gut: secretion of α-synuclein by enteric neurons.

Grathwohl SA, Steiner JA, Britschgi M, Brundin P.

J Neurochem. 2013 May;125(4):487-90. doi: 10.1111/jnc.12191. Epub 2013 Mar 1. No abstract available.

12.

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.

Luo J, Elwood F, Britschgi M, Villeda S, Zhang H, Ding Z, Zhu L, Alabsi H, Getachew R, Narasimhan R, Wabl R, Fainberg N, James ML, Wong G, Relton J, Gambhir SS, Pollard JW, Wyss-Coray T.

J Exp Med. 2013 Jan 14;210(1):157-72. doi: 10.1084/jem.20120412. Epub 2013 Jan 7.

13.

Post-marketing assessment of neuropsychiatric adverse events in influenza patients treated with oseltamivir: an updated review.

Toovey S, Prinssen EP, Rayner CR, Thakrar BT, Dutkowski R, Koerner A, Chu T, Sirzen-Zelenskaya A, Britschgi M, Bansod S, Donner B.

Adv Ther. 2012 Oct;29(10):826-48. doi: 10.1007/s12325-012-0050-8. Epub 2012 Oct 2. Review.

PMID:
23054689
14.

Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice.

Britschgi M, Takeda-Uchimura Y, Rockenstein E, Johns H, Masliah E, Wyss-Coray T.

J Neuroinflammation. 2012 Sep 18;9:220. doi: 10.1186/1742-2094-9-220.

15.

Inflammation and α-synuclein's prion-like behavior in Parkinson's disease--is there a link?

Lema Tomé CM, Tyson T, Rey NL, Grathwohl S, Britschgi M, Brundin P.

Mol Neurobiol. 2013 Apr;47(2):561-74. doi: 10.1007/s12035-012-8267-8. Epub 2012 Apr 29. Review.

16.

Heparan sulfate subdomains that are degraded by Sulf accumulate in cerebral amyloid ß plaques of Alzheimer's disease: evidence from mouse models and patients.

Hosono-Fukao T, Ohtake-Niimi S, Hoshino H, Britschgi M, Akatsu H, Hossain MM, Nishitsuji K, van Kuppevelt TH, Kimata K, Michikawa M, Wyss-Coray T, Uchimura K.

Am J Pathol. 2012 May;180(5):2056-67. doi: 10.1016/j.ajpath.2012.01.015. Epub 2012 Mar 17.

PMID:
22429964
17.

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T.

Nature. 2011 Aug 31;477(7362):90-4. doi: 10.1038/nature10357.

18.

Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome.

Britschgi M, Rufibach K, Huang SL, Clark CM, Kaye JA, Li G, Peskind ER, Quinn JF, Galasko DR, Wyss-Coray T.

Mol Cell Proteomics. 2011 Oct;10(10):M111.008862. doi: 10.1074/mcp.M111.008862. Epub 2011 Jul 8.

19.

Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans.

Link A, Hardie DL, Favre S, Britschgi MR, Adams DH, Sixt M, Cyster JG, Buckley CD, Luther SA.

Am J Pathol. 2011 Apr;178(4):1662-75. doi: 10.1016/j.ajpath.2010.12.039.

20.

Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis.

Moriyama M, Fukuhara T, Britschgi M, He Y, Narasimhan R, Villeda S, Molina H, Huber BT, Holers M, Wyss-Coray T.

J Neurosci. 2011 Mar 16;31(11):3981-9. doi: 10.1523/JNEUROSCI.3617-10.2011.

21.

CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19.

Britschgi MR, Favre S, Luther SA.

Eur J Immunol. 2010 May;40(5):1266-71. doi: 10.1002/eji.200939921.

22.

Processing-dependent and -independent pathways for recognition of iodinated contrast media by specific human T cells.

Keller M, Lerch M, Britschgi M, Tâche V, Gerber BO, Lüthi M, Lochmatter P, Kanny G, Bircher AJ, Christiansen C, Pichler WJ.

Clin Exp Allergy. 2010 Feb;40(2):257-68. doi: 10.1111/j.1365-2222.2009.03425.x. Epub 2009 Dec 16.

PMID:
20030663
23.

Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironment.

Tomei AA, Siegert S, Britschgi MR, Luther SA, Swartz MA.

J Immunol. 2009 Oct 1;183(7):4273-83. doi: 10.4049/jimmunol.0900835. Epub 2009 Sep 4.

24.

Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.

Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, Clark CM, Fagan AM, Galasko DR, Holtzman DM, Jutel M, Kaye JA, Lemere CA, Leszek J, Li G, Peskind ER, Quinn JF, Yesavage JA, Ghiso JA, Wyss-Coray T.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12145-50. doi: 10.1073/pnas.0904866106. Epub 2009 Jul 6.

25.

Blood protein signature for the early diagnosis of Alzheimer disease.

Britschgi M, Wyss-Coray T.

Arch Neurol. 2009 Feb;66(2):161-5. doi: 10.1001/archneurol.2008.530. Epub 2008 Dec 8. Review.

PMID:
19064741
26.

Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo.

Britschgi MR, Link A, Lissandrin TK, Luther SA.

J Immunol. 2008 Dec 1;181(11):7681-8.

27.

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.

Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, Wyss-Coray T.

J Clin Invest. 2008 Jun;118(6):2190-9. doi: 10.1172/JCI33585.

28.

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins.

Ray S, Britschgi M, Herbert C, Takeda-Uchimura Y, Boxer A, Blennow K, Friedman LF, Galasko DR, Jutel M, Karydas A, Kaye JA, Leszek J, Miller BL, Minthon L, Quinn JF, Rabinovici GD, Robinson WH, Sabbagh MN, So YT, Sparks DL, Tabaton M, Tinklenberg J, Yesavage JA, Tibshirani R, Wyss-Coray T.

Nat Med. 2007 Nov;13(11):1359-62. Epub 2007 Oct 14.

PMID:
17934472
29.

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

Link A, Vogt TK, Favre S, Britschgi MR, Acha-Orbea H, Hinz B, Cyster JG, Luther SA.

Nat Immunol. 2007 Nov;8(11):1255-65. Epub 2007 Sep 23.

PMID:
17893676
30.

Systemic and acquired immune responses in Alzheimer's disease.

Britschgi M, Wyss-Coray T.

Int Rev Neurobiol. 2007;82:205-33. Review.

PMID:
17678963
31.

Immune cells may fend off Alzheimer disease.

Britschgi M, Wyss-Coray T.

Nat Med. 2007 Apr;13(4):408-9. No abstract available.

PMID:
17415372
32.

Cross-reactivity patterns of T cells specific for iodinated contrast media.

Lerch M, Keller M, Britschgi M, Kanny G, Tache V, Schmid DA, Beeler A, Gerber BO, Luethi M, Bircher AJ, Christiansen C, Pichler WJ.

J Allergy Clin Immunol. 2007 Jun;119(6):1529-36. Epub 2007 Apr 6.

PMID:
17412404
33.

Involvement of drug-specific T cells in acute drug-induced interstitial nephritis.

Spanou Z, Keller M, Britschgi M, Yawalkar N, Fehr T, Neuweiler J, Gugger M, Mohaupt M, Pichler WJ.

J Am Soc Nephrol. 2006 Oct;17(10):2919-27. Epub 2006 Aug 30.

34.

T cell-regulated neutrophilic inflammation in autoinflammatory diseases.

Keller M, Spanou Z, Schaerli P, Britschgi M, Yawalkar N, Seitz M, Villiger PM, Pichler WJ.

J Immunol. 2005 Dec 1;175(11):7678-86.

35.

Characterization of human T cells that regulate neutrophilic skin inflammation.

Schaerli P, Britschgi M, Keller M, Steiner UC, Steinmann LS, Moser B, Pichler WJ.

J Immunol. 2004 Aug 1;173(3):2151-8.

36.

Cytotoxic mechanisms in different forms of T-cell-mediated drug allergies.

Kuechler PC, Britschgi M, Schmid S, Hari Y, Grabscheid B, Pichler WJ.

Allergy. 2004 Jun;59(6):613-22.

PMID:
15147446
37.

Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype, and cytokine profile of drug-specific T cell clones.

Naisbitt DJ, Britschgi M, Wong G, Farrell J, Depta JP, Chadwick DW, Pichler WJ, Pirmohamed M, Park BK.

Mol Pharmacol. 2003 Mar;63(3):732-41.

PMID:
12606784
38.

Non-covalent presentation of sulfamethoxazole to human CD4+ T cells is independent of distinct human leucocyte antigen-bound peptides.

Burkhart C, Britschgi M, Strasser I, Depta JP, von Greyerz S, Barnaba V, Pichler WJ.

Clin Exp Allergy. 2002 Nov;32(11):1635-43.

PMID:
12569986
39.

Molecular aspects of drug recognition by specific T cells.

Britschgi M, von Greyerz S, Burkhart C, Pichler WJ.

Curr Drug Targets. 2003 Jan;4(1):1-11. Review.

PMID:
12528985
40.

Acute generalized exanthematous pustulosis: role of cytotoxic T cells in pustule formation.

Schmid S, Kuechler PC, Britschgi M, Steiner UC, Yawalkar N, Limat A, Baltensperger K, Braathen L, Pichler WJ.

Am J Pathol. 2002 Dec;161(6):2079-86.

41.

Acute generalized exanthematous pustulosis, a clue to neutrophil-mediated inflammatory processes orchestrated by T cells.

Britschgi M, Pichler WJ.

Curr Opin Allergy Clin Immunol. 2002 Aug;2(4):325-31. Review.

PMID:
12130947
42.

Cellular and molecular pathophysiology of cutaneous drug reactions.

Pichler WJ, Yawalkar N, Britschgi M, Depta J, Strasser I, Schmid S, Kuechler P, Naisbitt D.

Am J Clin Dermatol. 2002;3(4):229-38. Review.

PMID:
12010068
43.

[So that the partner doesn't turn into a frog herself].

Britschgi M.

Krankenpfl Soins Infirm. 1999 Oct;92(10):16-9. German. No abstract available.

PMID:
11941823
44.

T-cell involvement in drug-induced acute generalized exanthematous pustulosis.

Britschgi M, Steiner UC, Schmid S, Depta JP, Senti G, Bircher A, Burkhart C, Yawalkar N, Pichler WJ.

J Clin Invest. 2001 Jun;107(11):1433-41.

45.

Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells.

Burkhart C, von Greyerz S, Depta JP, Naisbitt DJ, Britschgi M, Park KB, Pichler WJ.

Br J Pharmacol. 2001 Feb;132(3):623-30.

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