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Items: 1 to 50 of 51

1.

The droplet size of emulsion adjuvants has significant impact on their potency, due to differences in immune cell-recruitment and -activation.

Shah RR, Taccone M, Monaci E, Brito LA, Bonci A, O'Hagan DT, Amiji MM, Seubert A.

Sci Rep. 2019 Aug 8;9(1):11520. doi: 10.1038/s41598-019-47885-z.

2.

Influence of 2,4-D residues on the soil microbial community and growth of tree species.

Aguiar LM, Dos Santos JB, Barroso GM, Laia ML, Gonçalves JF, da Costa VAM, Brito LA.

Int J Phytoremediation. 2020;22(1):69-77. doi: 10.1080/15226514.2019.1644289. Epub 2019 Jul 25.

PMID:
31342787
3.

Corrigendum: Induction of Robust B Cell Responses After Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells.

Lindgren G, Ols S, Liang F, Thompson EA, Lin A, Hellgren F, Bahl K, John S, Yuzhakov O, Hassett KJ, Brito LA, Salter H, Ciaramella G, Loré K.

Front Immunol. 2019 Apr 2;10:614. doi: 10.3389/fimmu.2019.00614. eCollection 2019.

4.

Clinical and epidemiology evaluation of Aids-infected patients hospitalized between 2011 and 2016 in the Santos region of Brazil.

Focaccia R, Ribeiro MLA, Cossich ACC, Andrade RFL, Carbonari KFBSDF, Kallouf GA, Vieira RMR, Gemha JPL, Castro AA, Oliveira JPC, Haddad Filho FD, Dias JRP, Melo STL, Gonçalves BB, Lopes CS, Franceschi F, Brito LA, Bittar NJDS, Feijoó S, Reis GB.

Rev Soc Bras Med Trop. 2019 Apr 11;52:e20180126. doi: 10.1590/0037-8682-0126-2018.

5.

Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines.

Hassett KJ, Benenato KE, Jacquinet E, Lee A, Woods A, Yuzhakov O, Himansu S, Deterling J, Geilich BM, Ketova T, Mihai C, Lynn A, McFadyen I, Moore MJ, Senn JJ, Stanton MG, Almarsson Ö, Ciaramella G, Brito LA.

Mol Ther Nucleic Acids. 2019 Apr 15;15:1-11. doi: 10.1016/j.omtn.2019.01.013. Epub 2019 Feb 7.

6.

Seasonality of the hospitalizations at a dermatologic ward (2007-2017).

Brito LAR, Nascimento ACMD, Marque C, Miot HA.

An Bras Dermatol. 2018 Sep-Oct;93(5):755-758. doi: 10.1590/abd1806-4841.20187309.

7.

Complexity of the 5' Untranslated Region of EIF4A3, a Critical Factor for Craniofacial and Neural Development.

Hsia GSP, Musso CM, Alvizi L, Brito LA, Kobayashi GS, Pavanello RCM, Zatz M, Gardham A, Wakeling E, Zechi-Ceide RM, Bertola D, Passos-Bueno MR.

Front Genet. 2018 Apr 25;9:149. doi: 10.3389/fgene.2018.00149. eCollection 2018.

8.

Stable Nanoemulsions for the Delivery of Small Molecule Immune Potentiators.

Lodaya RN, Brito LA, Wu TYH, Miller AT, Otten GR, Singh M, O'Hagan DT.

J Pharm Sci. 2018 Sep;107(9):2310-2314. doi: 10.1016/j.xphs.2018.05.012. Epub 2018 Jun 5.

PMID:
29883663
10.

Platypnea-Orthodeoxia Syndrome Masked by Delirium in an 85-Year-Old Woman.

Brito LAR, Fukushima FB, Bazan R, Fusco DR, Vidal EIO.

J Am Med Dir Assoc. 2018 Jan;19(1):92-93. doi: 10.1016/j.jamda.2017.10.022. Epub 2017 Nov 28. No abstract available.

PMID:
29191765
11.

Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells.

Lindgren G, Ols S, Liang F, Thompson EA, Lin A, Hellgren F, Bahl K, John S, Yuzhakov O, Hassett KJ, Brito LA, Salter H, Ciaramella G, Loré K.

Front Immunol. 2017 Nov 13;8:1539. doi: 10.3389/fimmu.2017.01539. eCollection 2017. Erratum in: Front Immunol. 2019 Apr 02;10:614.

12.

MRPL53, a New Candidate Gene for Orofacial Clefting, Identified Using an eQTL Approach.

Masotti C, Brito LA, Nica AC, Ludwig KU, Nunes K, Savastano CP, Malcher C, Ferreira SG, Kobayashi GS, Bueno DF, Alonso N, Franco D, Rojas-Martinez A, Dos Santos SE, Galante PA, Meyer D, Hünemeier T, Mangold E, Dermitzakis ET, Passos-Bueno MR.

J Dent Res. 2018 Jan;97(1):33-40. doi: 10.1177/0022034517735805. Epub 2017 Oct 20.

PMID:
29053389
13.

Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques.

Liang F, Lindgren G, Lin A, Thompson EA, Ols S, Röhss J, John S, Hassett K, Yuzhakov O, Bahl K, Brito LA, Salter H, Ciaramella G, Loré K.

Mol Ther. 2017 Dec 6;25(12):2635-2647. doi: 10.1016/j.ymthe.2017.08.006. Epub 2017 Aug 12.

14.

Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects.

Alvizi L, Ke X, Brito LA, Seselgyte R, Moore GE, Stanier P, Passos-Bueno MR.

Sci Rep. 2017 May 26;7(1):2441. doi: 10.1038/s41598-017-02721-0.

15.

Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses.

Bahl K, Senn JJ, Yuzhakov O, Bulychev A, Brito LA, Hassett KJ, Laska ME, Smith M, Almarsson Ö, Thompson J, Ribeiro AM, Watson M, Zaks T, Ciaramella G.

Mol Ther. 2017 Jun 7;25(6):1316-1327. doi: 10.1016/j.ymthe.2017.03.035. Epub 2017 Apr 27.

16.

[Management practices in medium-sized private hospitals in São Paulo, Brazil].

Brito LA, Malik AM, Brito E, Bulgacov S, Andreassi T.

Cad Saude Publica. 2017 Apr 3;33(3):e00030715. doi: 10.1590/0102-311X00030715. Portuguese.

17.

Exomic variants of an elderly cohort of Brazilians in the ABraOM database.

Naslavsky MS, Yamamoto GL, de Almeida TF, Ezquina SAM, Sunaga DY, Pho N, Bozoklian D, Sandberg TOM, Brito LA, Lazar M, Bernardo DV, Amaro E Jr, Duarte YAO, Lebrão ML, Passos-Bueno MR, Zatz M.

Hum Mutat. 2017 Jul;38(7):751-763. doi: 10.1002/humu.23220. Epub 2017 May 3.

PMID:
28332257
18.

The influence of population stratification on genetic markers associated with type 1 diabetes.

Gomes KF, Santos AS, Semzezem C, Correia MR, Brito LA, Ruiz MO, Fukui RT, Matioli SR, Passos-Bueno MR, Silva ME.

Sci Rep. 2017 Mar 6;7:43513. doi: 10.1038/srep43513.

19.

Overview of Vaccine Adjuvants: Introduction, History, and Current Status.

Shah RR, Hassett KJ, Brito LA.

Methods Mol Biol. 2017;1494:1-13. Review.

PMID:
27718182
20.

Impact of rare variants in ARHGAP29 to the etiology of oral clefts: role of loss-of-function vs missense variants.

Savastano CP, Brito LA, Faria ÁC, Setó-Salvia N, Peskett E, Musso CM, Alvizi L, Ezquina SA, James C, GOSgene, Beales P, Lees M, Moore GE, Stanier P, Passos-Bueno MR.

Clin Genet. 2017 May;91(5):683-689. doi: 10.1111/cge.12823. Epub 2016 Jul 26.

PMID:
27350171
21.

Rare Variants in the Epithelial Cadherin Gene Underlying the Genetic Etiology of Nonsyndromic Cleft Lip with or without Cleft Palate.

Brito LA, Yamamoto GL, Melo S, Malcher C, Ferreira SG, Figueiredo J, Alvizi L, Kobayashi GS, Naslavsky MS, Alonso N, Felix TM, Zatz M, Seruca R, Passos-Bueno MR.

Hum Mutat. 2015 Nov;36(11):1029-33. doi: 10.1002/humu.22827. Epub 2015 Aug 3.

PMID:
26123647
22.

Self-amplifying mRNA vaccines.

Brito LA, Kommareddy S, Maione D, Uematsu Y, Giovani C, Berlanda Scorza F, Otten GR, Yu D, Mandl CW, Mason PW, Dormitzer PR, Ulmer JB, Geall AJ.

Adv Genet. 2015;89:179-233. doi: 10.1016/bs.adgen.2014.10.005. Epub 2014 Dec 4.

PMID:
25620012
23.

The development of self-emulsifying oil-in-water emulsion adjuvant and an evaluation of the impact of droplet size on performance.

Shah RR, Dodd S, Schaefer M, Ugozzoli M, Singh M, Otten GR, Amiji MM, O'Hagan DT, Brito LA.

J Pharm Sci. 2015 Apr;104(4):1352-61. doi: 10.1002/jps.24337. Epub 2015 Jan 19.

PMID:
25600347
24.

The impact of size on particulate vaccine adjuvants.

Shah RR, O'Hagan DT, Amiji MM, Brito LA.

Nanomedicine (Lond). 2014 Dec;9(17):2671-81. doi: 10.2217/nnm.14.193.

PMID:
25529570
25.

Rational design of small molecules as vaccine adjuvants.

Wu TY, Singh M, Miller AT, De Gregorio E, Doro F, D'Oro U, Skibinski DA, Mbow ML, Bufali S, Herman AE, Cortez A, Li Y, Nayak BP, Tritto E, Filippi CM, Otten GR, Brito LA, Monaci E, Li C, Aprea S, Valentini S, Calabrό S, Laera D, Brunelli B, Caproni E, Malyala P, Panchal RG, Warren TK, Bavari S, O'Hagan DT, Cooke MP, Valiante NM.

Sci Transl Med. 2014 Nov 19;6(263):263ra160. doi: 10.1126/scitranslmed.3009980.

26.

Potent immune responses in rhesus macaques induced by nonviral delivery of a self-amplifying RNA vaccine expressing HIV type 1 envelope with a cationic nanoemulsion.

Bogers WM, Oostermeijer H, Mooij P, Koopman G, Verschoor EJ, Davis D, Ulmer JB, Brito LA, Cu Y, Banerjee K, Otten GR, Burke B, Dey A, Heeney JL, Shen X, Tomaras GD, Labranche C, Montefiori DC, Liao HX, Haynes B, Geall AJ, Barnett SW.

J Infect Dis. 2015 Mar 15;211(6):947-55. doi: 10.1093/infdis/jiu522. Epub 2014 Sep 18.

27.

Genetics and genomics in Brazil: a promising future.

Passos-Bueno MR, Bertola D, Horovitz DD, de Faria Ferraz VE, Brito LA.

Mol Genet Genomic Med. 2014 Jul;2(4):280-91. doi: 10.1002/mgg3.95. No abstract available.

28.

A cationic nanoemulsion for the delivery of next-generation RNA vaccines.

Brito LA, Chan M, Shaw CA, Hekele A, Carsillo T, Schaefer M, Archer J, Seubert A, Otten GR, Beard CW, Dey AK, Lilja A, Valiante NM, Mason PW, Mandl CW, Barnett SW, Dormitzer PR, Ulmer JB, Singh M, O'Hagan DT, Geall AJ.

Mol Ther. 2014 Dec;22(12):2118-29. doi: 10.1038/mt.2014.133. Epub 2014 Jul 16.

29.

Designing and building the next generation of improved vaccine adjuvants.

Brito LA, O'Hagan DT.

J Control Release. 2014 Sep 28;190:563-79. doi: 10.1016/j.jconrel.2014.06.027. Epub 2014 Jul 3. Review.

PMID:
24998942
30.

Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines.

Deering RP, Kommareddy S, Ulmer JB, Brito LA, Geall AJ.

Expert Opin Drug Deliv. 2014 Jun;11(6):885-99. doi: 10.1517/17425247.2014.901308. Epub 2014 Mar 26. Review.

PMID:
24665982
31.

MTHFR rs2274976 polymorphism is a risk marker for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.

de Aquino SN, Hoshi R, Bagordakis E, Pucciarelli MG, Messetti AC, Moreira H, Bufalino A, Borges A, Rangel AL, Brito LA, Oliveira Swerts MS, Martelli-Junior H, Line SR, Graner E, Reis SR, Passos-Bueno MR, Coletta RD.

Birth Defects Res A Clin Mol Teratol. 2014 Jan;100(1):30-5. doi: 10.1002/bdra.23199. Epub 2013 Nov 19.

PMID:
24254627
32.

Ponderal behavior of rats fed an omegas 3, 6 and 9 enriched diet submitted to colon carcinogenesis induced by azoxymethane.

Burlamaqui IM, Dornelas CA, Brito LA, Trindade JW Jr, Sucupira RM, Veras LB, Azevedo OG, Vasconcelos PR, Rodrigues LV.

Acta Cir Bras. 2013 Oct;28(10):721-7.

33.

Rapidly produced SAM(®) vaccine against H7N9 influenza is immunogenic in mice.

Hekele A, Bertholet S, Archer J, Gibson DG, Palladino G, Brito LA, Otten GR, Brazzoli M, Buccato S, Bonci A, Casini D, Maione D, Qi ZQ, Gill JE, Caiazza NC, Urano J, Hubby B, Gao GF, Shu Y, De Gregorio E, Mandl CW, Mason PW, Settembre EC, Ulmer JB, Craig Venter J, Dormitzer PR, Rappuoli R, Geall AJ.

Emerg Microbes Infect. 2013 Aug;2(8):e52. doi: 10.1038/emi.2013.54. Epub 2013 Aug 14.

34.

Vaccine adjuvant formulations: a pharmaceutical perspective.

Brito LA, Malyala P, O'Hagan DT.

Semin Immunol. 2013 Apr;25(2):130-45. doi: 10.1016/j.smim.2013.05.007. Epub 2013 Jul 12. Review.

PMID:
23850011
35.

Generation of a parvovirus B19 vaccine candidate.

Chandramouli S, Medina-Selby A, Coit D, Schaefer M, Spencer T, Brito LA, Zhang P, Otten G, Mandl CW, Mason PW, Dormitzer PR, Settembre EC.

Vaccine. 2013 Aug 20;31(37):3872-8. doi: 10.1016/j.vaccine.2013.06.062. Epub 2013 Jul 2.

PMID:
23827313
36.

Hepatic repercussions of azoxymethane-induced colorectal carcinogenesis.

Burlamaqui IM, Dornelas CA, Almeida PR, Jamacaru FV, Mota DM, Mesquita FJ, de Brito LA, Veras LB, Rodrigues LV.

Rev Col Bras Cir. 2013 Mar-Apr;40(2):137-41. English, Portuguese.

37.

Polymorphisms at regions 1p22.1 (rs560426) and 8q24 (rs1530300) are risk markers for nonsyndromic cleft lip and/or palate in the Brazilian population.

Bagordakis E, Paranaiba LM, Brito LA, de Aquino SN, Messetti AC, Martelli-Junior H, Swerts MS, Graner E, Passos-Bueno MR, Coletta RD.

Am J Med Genet A. 2013 May;161A(5):1177-80. doi: 10.1002/ajmg.a.35830. Epub 2013 Mar 26. No abstract available.

PMID:
23532876
38.

Contribution of polymorphisms in genes associated with craniofacial development to the risk of nonsyndromic cleft lip and/or palate in the Brazilian population.

Paranaíba LM, de Aquino SN, Bufalino A, Martelli-Júnior H, Graner E, Brito LA, e Passos-Bueno MR, Coletta RD, Swerts MS.

Med Oral Patol Oral Cir Bucal. 2013 May 1;18(3):e414-20.

39.

Vectored co-delivery of human cytomegalovirus gH and gL proteins elicits potent complement-independent neutralizing antibodies.

Loomis RJ, Lilja AE, Monroe J, Balabanis KA, Brito LA, Palladino G, Franti M, Mandl CW, Barnett SW, Mason PW.

Vaccine. 2013 Jan 30;31(6):919-26. doi: 10.1016/j.vaccine.2012.12.009. Epub 2012 Dec 14.

PMID:
23246547
40.

Genetics and management of the patient with orofacial cleft.

Brito LA, Meira JG, Kobayashi GS, Passos-Bueno MR.

Plast Surg Int. 2012;2012:782821. doi: 10.1155/2012/782821. Epub 2012 Nov 1.

41.

Nonviral delivery of self-amplifying RNA vaccines.

Geall AJ, Verma A, Otten GR, Shaw CA, Hekele A, Banerjee K, Cu Y, Beard CW, Brito LA, Krucker T, O'Hagan DT, Singh M, Mason PW, Valiante NM, Dormitzer PR, Barnett SW, Rappuoli R, Ulmer JB, Mandl CW.

Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14604-9. doi: 10.1073/pnas.1209367109. Epub 2012 Aug 20.

42.

IRF6 is a risk factor for nonsyndromic cleft lip in the Brazilian population.

Brito LA, Bassi CF, Masotti C, Malcher C, Rocha KM, Schlesinger D, Bueno DF, Cruz LA, Barbara LK, Bertola DR, Meyer D, Franco D, Alonso N, Passos-Bueno MR.

Am J Med Genet A. 2012 Sep;158A(9):2170-5. doi: 10.1002/ajmg.a.35526. Epub 2012 Aug 6.

PMID:
22887868
43.

Region 8q24 is a susceptibility locus for nonsyndromic oral clefting in Brazil.

Brito LA, Paranaiba LM, Bassi CF, Masotti C, Malcher C, Schlesinger D, Rocha KM, Cruz LA, Bárbara LK, Alonso N, Franco D, Bagordakis E, Martelli H Jr, Meyer D, Coletta RD, Passos-Bueno MR.

Birth Defects Res A Clin Mol Teratol. 2012 Jun;94(6):464-8. doi: 10.1002/bdra.23011. Epub 2012 Apr 18.

PMID:
22511506
44.

An alternative renewable source of squalene for use in emulsion adjuvants.

Brito LA, Chan M, Baudner B, Gallorini S, Santos G, O'Hagan DT, Singh M.

Vaccine. 2011 Aug 26;29(37):6262-8. doi: 10.1016/j.vaccine.2011.06.067. Epub 2011 Jun 30.

PMID:
21723355
45.

Genetic contribution for non-syndromic cleft lip with or without cleft palate (NS CL/P) in different regions of Brazil and implications for association studies.

Brito LA, Cruz LA, Rocha KM, Barbara LK, Silva CB, Bueno DF, Aguena M, Bertola DR, Franco D, Costa AM, Alonso N, Otto PA, Passos-Bueno MR.

Am J Med Genet A. 2011 Jul;155A(7):1581-7. doi: 10.1002/ajmg.a.34036. Epub 2011 Jun 2.

PMID:
21638763
46.

Angiogenic activity of Calendula officinalis flowers L. in rats.

Parente LM, Andrade MA, Brito LA, Moura VM, Miguel MP, Lino-Júnior Rde S, Tresvenzol LF, Paula JR, Paulo NM.

Acta Cir Bras. 2011 Feb;26(1):19-24.

47.

Non-viral eNOS gene delivery and transfection with stents for the treatment of restenosis.

Brito LA, Chandrasekhar S, Little SR, Amiji MM.

Biomed Eng Online. 2010 Sep 27;9:56. doi: 10.1186/1475-925X-9-56.

48.

Acceptable levels of endotoxin in vaccine formulations during preclinical research.

Brito LA, Singh M.

J Pharm Sci. 2011 Jan;100(1):34-7. doi: 10.1002/jps.22267. Review.

PMID:
20575063
49.

In vitro and in vivo studies of local arterial gene delivery and transfection using lipopolyplexes-embedded stents.

Brito LA, Chandrasekhar S, Little SR, Amiji MM.

J Biomed Mater Res A. 2010 Apr;93(1):325-36. doi: 10.1002/jbm.a.32488.

PMID:
19569206
50.

Accumulative sodium poisoning in Brazilian swine fed whey.

Brito LA, Matos MP, Sobestiansky J, Sucupira MC, Ortolani EL.

Vet Hum Toxicol. 2001 Apr;43(2):88-90.

PMID:
11308126

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