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Items: 8


Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.

Grimaldi M, Karaca M, Latini L, Brioudes E, Schalch T, Maechler P.

Hum Mol Genet. 2017 Sep 15;26(18):3453-3465. doi: 10.1093/hmg/ddx213.


Asymmetrical distribution of δ and PP cells in human pancreatic islets.

Barbieux C, Parnaud G, Lavallard V, Brioudes E, Meyer J, Alibashe Ahmed M, Berishvili E, Berney T, Bosco D.

J Endocrinol. 2016 May;229(2):123-32. doi: 10.1530/JOE-15-0542. Epub 2016 Mar 1.


Compartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neurons.

Kanaani J, Cianciaruso C, Phelps EA, Pasquier M, Brioudes E, Billestrup N, Baekkeskov S.

PLoS One. 2015 Feb 3;10(2):e0117130. doi: 10.1371/journal.pone.0117130. eCollection 2015.


The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A.

Gharbi-Ayachi A, Labbé JC, Burgess A, Vigneron S, Strub JM, Brioudes E, Van-Dorsselaer A, Castro A, Lorca T.

Science. 2010 Dec 17;330(6011):1673-7. doi: 10.1126/science.1197048.


Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle.

Lorca T, Bernis C, Vigneron S, Burgess A, Brioudes E, Labbé JC, Castro A.

J Cell Sci. 2010 Jul 1;123(Pt 13):2281-91. doi: 10.1242/jcs.064527.


Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance.

Burgess A, Vigneron S, Brioudes E, Labbé JC, Lorca T, Castro A.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12564-9. doi: 10.1073/pnas.0914191107. Epub 2010 Jun 10.


RSK2 is a kinetochore-associated protein that participates in the spindle assembly checkpoint.

Vigneron S, Brioudes E, Burgess A, Labbé JC, Lorca T, Castro A.

Oncogene. 2010 Jun 17;29(24):3566-74. doi: 10.1038/onc.2010.105. Epub 2010 Apr 12.


Greatwall maintains mitosis through regulation of PP2A.

Vigneron S, Brioudes E, Burgess A, Labbé JC, Lorca T, Castro A.

EMBO J. 2009 Sep 16;28(18):2786-93. doi: 10.1038/emboj.2009.228. Epub 2009 Aug 13.

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