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Items: 1 to 50 of 113

1.

AAV2-BDNF promotes respiratory axon plasticity and recovery of diaphragm function following spinal cord injury.

Charsar BA, Brinton MA, Locke K, Chen AY, Ghosh B, Urban MW, Komaravolu S, Krishnamurthy K, Smit R, Pasinelli P, Wright MC, Smith GM, Lepore AC.

FASEB J. 2019 Oct 2:fj201901730R. doi: 10.1096/fj.201901730R. [Epub ahead of print]

PMID:
31577916
2.

Z-DNA-Binding Protein 1 Is Critical for Controlling Virus Replication and Survival in West Nile Virus Encephalitis.

Rothan HA, Arora K, Natekar JP, Strate PG, Brinton MA, Kumar M.

Front Microbiol. 2019 Sep 11;10:2089. doi: 10.3389/fmicb.2019.02089. eCollection 2019.

3.

RNase L antiviral activity is not a critical component of the Oas1b-mediated flavivirus resistance phenotype.

Madden JC Jr, Cui D, Brinton MA.

J Virol. 2019 Aug 28. pii: JVI.00946-19. doi: 10.1128/JVI.00946-19. [Epub ahead of print]

PMID:
31462564
4.

Biochemical characterization of the mouse ABCF3 protein, a partner of the flavivirus-resistance protein OAS1B.

Peterson E, Shippee E, Brinton MA, Kaur P.

J Biol Chem. 2019 Oct 11;294(41):14937-14952. doi: 10.1074/jbc.RA119.008477. Epub 2019 Aug 14.

PMID:
31413116
5.

Zika Virus Infection Induces DNA Damage Response in Human Neural Progenitors That Enhances Viral Replication.

Hammack C, Ogden SC, Madden JC Jr, Medina A, Xu C, Phillips E, Son Y, Cone A, Giovinazzi S, Didier RA, Gilbert DM, Song H, Ming G, Wen Z, Brinton MA, Gunjan A, Tang H.

J Virol. 2019 Sep 30;93(20). pii: e00638-19. doi: 10.1128/JVI.00638-19. Print 2019 Oct 15.

PMID:
31375586
6.

Editorial overview: Antiviral strategies: Antiviral drug development for single-stranded RNA viruses.

Brinton MA, Plemper RK.

Curr Opin Virol. 2019 Apr;35:iii-v. doi: 10.1016/j.coviro.2019.05.011. Epub 2019 May 29. No abstract available.

PMID:
31151832
7.

Insertion position as well as the inserted TRS and gene sequences differentially affect the retention of foreign gene expression by simian hemorrhagic fever virus (SHFV).

Di H, Morantz EK, Sadhwani H, Madden JC Jr, Brinton MA.

Virology. 2018 Dec;525:150-160. doi: 10.1016/j.virol.2018.09.014. Epub 2018 Oct 1.

PMID:
30286427
8.

New insights about the regulation of Nidovirus subgenomic mRNA synthesis.

Di H, McIntyre AA, Brinton MA.

Virology. 2018 Apr;517:38-43. doi: 10.1016/j.virol.2018.01.026. Epub 2018 Feb 21.

9.

Antiviral activity of K22 against members of the order Nidovirales.

Rappe JCF, de Wilde A, Di H, Müller C, Stalder H, V'kovski P, Snijder E, Brinton MA, Ziebuhr J, Ruggli N, Thiel V.

Virus Res. 2018 Feb 15;246:28-34. doi: 10.1016/j.virusres.2018.01.002. Epub 2018 Jan 11.

10.

Expanded subgenomic mRNA transcriptome and coding capacity of a nidovirus.

Di H, Madden JC Jr, Morantz EK, Tang HY, Graham RL, Baric RS, Brinton MA.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):E8895-E8904. doi: 10.1073/pnas.1706696114. Epub 2017 Oct 4.

11.

How do flavivirus-infected cells resist arsenite-induced stress granule formation?

Basu M, Brinton MA.

Future Virol. 2017 Jun;12(6):247-249. doi: 10.2217/fvl-2017-0033. Epub 2017 Jun 8. No abstract available.

12.

Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells.

Basu M, Courtney SC, Brinton MA.

PLoS Pathog. 2017 Feb 27;13(2):e1006240. doi: 10.1371/journal.ppat.1006240. eCollection 2017 Feb.

13.

Spectral and Hydrodynamic Analysis of West Nile Virus RNA-Protein Interactions by Multiwavelength Sedimentation Velocity in the Analytical Ultracentrifuge.

Zhang J, Pearson JZ, Gorbet GE, Cölfen H, Germann MW, Brinton MA, Demeler B.

Anal Chem. 2017 Jan 3;89(1):862-870. doi: 10.1021/acs.analchem.6b03926. Epub 2016 Dec 15.

14.

Positive strand RNA virus replication: It depends on the ends.

Brinton MA, Miller WA.

Virus Res. 2015 Aug 3;206:1-2. doi: 10.1016/j.virusres.2015.06.010. No abstract available.

PMID:
26094090
15.

Functions of the 3' and 5' genome RNA regions of members of the genus Flavivirus.

Brinton MA, Basu M.

Virus Res. 2015 Aug 3;206:108-19. doi: 10.1016/j.virusres.2015.02.006. Epub 2015 Feb 13. Review.

16.

Effect of Temperature and Process on Quantity and Composition of Laboratory-generated Bitumen Emissions.

Bolliet C, Kriech AJ, Juery C, Vaissiere M, Brinton MA, Osborn LV.

J Occup Environ Hyg. 2015;12(7):438-49. doi: 10.1080/15459624.2015.1009982.

PMID:
25647623
17.

A simian hemorrhagic fever virus isolate from persistently infected baboons efficiently induces hemorrhagic fever disease in Japanese macaques.

Vatter HA, Donaldson EF, Huynh J, Rawlings S, Manoharan M, Legasse A, Planer S, Dickerson MF, Lewis AD, Colgin LM, Axthelm MK, Pecotte JK, Baric RS, Wong SW, Brinton MA.

Virology. 2015 Jan 1;474:186-98. doi: 10.1016/j.virol.2014.10.018. Epub 2014 Nov 19.

18.

Simian hemorrhagic fever virus: Recent advances.

Brinton MA, Di H, Vatter HA.

Virus Res. 2015 Apr 16;202:112-9. doi: 10.1016/j.virusres.2014.11.024. Epub 2014 Nov 29. Review.

19.

Corrigendum to "Each of the eight simian hemorrhagic fever virus minor structural proteins is functionally important" [Virology 462-463 (2014) 351-362].

Vatter HA, Di H, Donaldson EF, Baric RS, Brinton MA.

Virology. 2014 Sep;464-465:461. doi: 10.1016/j.virol.2014.07.045. Epub 2014 Aug 10. No abstract available.

20.

Each of the eight simian hemorrhagic fever virus minor structural proteins is functionally important.

Vatter HA, Di H, Donaldson EF, Baric RS, Brinton MA.

Virology. 2014 Aug;462-463:351-62. doi: 10.1016/j.virol.2014.06.001. Epub 2014 Jul 16. Erratum in: Virology. 2014 Sep;464-465:461.

21.

Functional analyses of the three simian hemorrhagic fever virus nonstructural protein 1 papain-like proteases.

Vatter HA, Di H, Donaldson EF, Radu GU, Maines TR, Brinton MA.

J Virol. 2014 Aug;88(16):9129-40. doi: 10.1128/JVI.01020-14. Epub 2014 Jun 4.

22.

Genetic resistance to flaviviruses.

Brinton MA.

Monoclon Antib Immunodiagn Immunother. 2014 Jun;33(3):183-5. doi: 10.1089/mab.2014.0009. Epub 2014 Jun 3. No abstract available.

23.

Cell death-inducing DFFA-like effector b is required for hepatitis C virus entry into hepatocytes.

Wu X, Lee EM, Hammack C, Robotham JM, Basu M, Lang J, Brinton MA, Tang H.

J Virol. 2014 Aug;88(15):8433-44. doi: 10.1128/JVI.00081-14. Epub 2014 May 14.

24.

Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.

Huang H, Zeqiraj E, Dong B, Jha BK, Duffy NM, Orlicky S, Thevakumaran N, Talukdar M, Pillon MC, Ceccarelli DF, Wan LC, Juang YC, Mao DY, Gaughan C, Brinton MA, Perelygin AA, Kourinov I, Guarné A, Silverman RH, Sicheri F.

Mol Cell. 2014 Jan 23;53(2):221-34. doi: 10.1016/j.molcel.2013.12.025.

25.

Replication cycle and molecular biology of the West Nile virus.

Brinton MA.

Viruses. 2013 Dec 27;6(1):13-53. doi: 10.3390/v6010013. Review.

26.
27.
28.

Identification of cis-acting nucleotides and a structural feature in West Nile virus 3'-terminus RNA that facilitate viral minus strand RNA synthesis.

Davis WG, Basu M, Elrod EJ, Germann MW, Brinton MA.

J Virol. 2013 Jul;87(13):7622-36. doi: 10.1128/JVI.00212-13. Epub 2013 May 1.

29.

Identification of novel host cell binding partners of Oas1b, the protein conferring resistance to flavivirus-induced disease in mice.

Courtney SC, Di H, Stockman BM, Liu H, Scherbik SV, Brinton MA.

J Virol. 2012 Aug;86(15):7953-63. doi: 10.1128/JVI.00333-12. Epub 2012 May 23.

30.

Type 1 IFN-independent activation of a subset of interferon stimulated genes in West Nile virus Eg101-infected mouse cells.

Pulit-Penaloza JA, Scherbik SV, Brinton MA.

Virology. 2012 Apr 10;425(2):82-94. doi: 10.1016/j.virol.2012.01.006. Epub 2012 Feb 3.

31.

Activation of Oas1a gene expression by type I IFN requires both STAT1 and STAT2 while only STAT2 is required for Oas1b activation.

Pulit-Penaloza JA, Scherbik SV, Brinton MA.

Virology. 2012 Apr 10;425(2):71-81. doi: 10.1016/j.virol.2011.11.025. Epub 2012 Feb 3.

32.

West nile virus infections suppress early viral RNA synthesis and avoid inducing the cell stress granule response.

Courtney SC, Scherbik SV, Stockman BM, Brinton MA.

J Virol. 2012 Apr;86(7):3647-57. doi: 10.1128/JVI.06549-11. Epub 2012 Jan 18.

33.

Single nucleotide polymorphism in the promoter region of the CD209 gene is associated with human predisposition to severe forms of tick-borne encephalitis.

Barkhash AV, Perelygin AA, Babenko VN, Brinton MA, Voevoda MI.

Antiviral Res. 2012 Jan;93(1):64-8. doi: 10.1016/j.antiviral.2011.10.017. Epub 2011 Oct 28.

PMID:
22061615
34.

West Nile virus infection does not induce PKR activation in rodent cells.

Elbahesh H, Scherbik SV, Brinton MA.

Virology. 2011 Dec 5;421(1):51-60. doi: 10.1016/j.virol.2011.08.008. Epub 2011 Oct 7.

35.

Host genetic risk factors for West Nile virus infection and disease progression.

Bigham AW, Buckingham KJ, Husain S, Emond MJ, Bofferding KM, Gildersleeve H, Rutherford A, Astakhova NM, Perelygin AA, Busch MP, Murray KO, Sejvar JJ, Green S, Kriesel J, Brinton MA, Bamshad M.

PLoS One. 2011;6(9):e24745. doi: 10.1371/journal.pone.0024745. Epub 2011 Sep 15.

36.

West Nile virus (WNV) genome RNAs with up to three adjacent mutations that disrupt long distance 5'-3' cyclization sequence basepairs are viable.

Basu M, Brinton MA.

Virology. 2011 Mar 30;412(1):220-32. doi: 10.1016/j.virol.2011.01.008. Epub 2011 Feb 2.

37.

The Flvr-encoded murine oligoadenylate synthetase 1b (Oas1b) suppresses 2-5A synthesis in intact cells.

Elbahesh H, Jha BK, Silverman RH, Scherbik SV, Brinton MA.

Virology. 2011 Jan 20;409(2):262-70. doi: 10.1016/j.virol.2010.10.016. Epub 2010 Nov 5.

38.

Variability in the 2'-5'-oligoadenylate synthetase gene cluster is associated with human predisposition to tick-borne encephalitis virus-induced disease.

Barkhash AV, Perelygin AA, Babenko VN, Myasnikova NG, Pilipenko PI, Romaschenko AG, Voevoda MI, Brinton MA.

J Infect Dis. 2010 Dec 15;202(12):1813-8. doi: 10.1086/657418. Epub 2010 Nov 4.

PMID:
21050126
39.

Virus-induced Ca2+ influx extends survival of west nile virus-infected cells.

Scherbik SV, Brinton MA.

J Virol. 2010 Sep;84(17):8721-31. doi: 10.1128/JVI.00144-10. Epub 2010 Jun 10.

40.

Characterization of equine and other vertebrate TLR3, TLR7, and TLR8 genes.

Astakhova NM, Perelygin AA, Zharkikh AA, Lear TL, Coleman SJ, MacLeod JN, Brinton MA.

Immunogenetics. 2009 Jul;61(7):529-39. doi: 10.1007/s00251-009-0381-z. Epub 2009 Jul 1.

PMID:
19568743
41.
42.

Case of yellow fever vaccine--associated viscerotropic disease with prolonged viremia, robust adaptive immune responses, and polymorphisms in CCR5 and RANTES genes.

Pulendran B, Miller J, Querec TD, Akondy R, Moseley N, Laur O, Glidewell J, Monson N, Zhu T, Zhu H, Staprans S, Lee D, Brinton MA, Perelygin AA, Vellozzi C, Brachman P Jr, Lalor S, Teuwen D, Eidex RB, Cetron M, Priddy F, del Rio C, Altman J, Ahmed R.

J Infect Dis. 2008 Aug 15;198(4):500-7. doi: 10.1086/590187.

43.

Concerted evolution of vertebrate CCR2 and CCR5 genes and the origin of a recombinant equine CCR5/2 gene.

Perelygin AA, Zharkikh AA, Astakhova NM, Lear TL, Brinton MA.

J Hered. 2008 Sep-Oct;99(5):500-11. doi: 10.1093/jhered/esn029. Epub 2008 May 22.

PMID:
18502735
44.

Knock-in of the Oas1b(r) allele into a flavivirus-induced disease susceptible mouse generates the resistant phenotype.

Scherbik SV, Kluetzman K, Perelygin AA, Brinton MA.

Virology. 2007 Nov 25;368(2):232-7. Epub 2007 Sep 27.

45.

Interactions between the West Nile virus capsid protein and the host cell-encoded phosphatase inhibitor, I2PP2A.

Hunt TA, Urbanowski MD, Kakani K, Law LM, Brinton MA, Hobman TC.

Cell Microbiol. 2007 Nov;9(11):2756-66. Epub 2007 Sep 14.

PMID:
17868381
46.

Characterization of the equine 2'-5' oligoadenylate synthetase 1 (OAS1) and ribonuclease L (RNASEL) innate immunity genes.

Rios JJ, Perelygin AA, Long MT, Lear TL, Zharkikh AA, Brinton MA, Adelson DL.

BMC Genomics. 2007 Sep 7;8:313.

48.
49.
50.

The mammalian 2'-5' oligoadenylate synthetase gene family: evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla.

Perelygin AA, Zharkikh AA, Scherbik SV, Brinton MA.

J Mol Evol. 2006 Oct;63(4):562-76. Epub 2006 Oct 5.

PMID:
17024523

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