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Items: 34


A reference genome of the Chinese hamster based on a hybrid assembly strategy.

Rupp O, MacDonald ML, Li S, Dhiman H, Polson S, Griep S, Heffner K, Hernandez I, Brinkrolf K, Jadhav V, Samoudi M, Hao H, Kingham B, Goesmann A, Betenbaugh MJ, Lewis NE, Borth N, Lee KH.

Biotechnol Bioeng. 2018 Aug;115(8):2087-2100. doi: 10.1002/bit.26722. Epub 2018 May 29.


Integrative analysis of DNA methylation and gene expression in butyrate-treated CHO cells.

Wippermann A, Rupp O, Brinkrolf K, Hoffrogge R, Noll T.

J Biotechnol. 2017 Sep 10;257:150-161. doi: 10.1016/j.jbiotec.2016.11.020. Epub 2016 Nov 24.


The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms.

Rupp O, Brinkrolf K, Buerth C, Kunigo M, Schneider J, Jaenicke S, Goesmann A, Pühler A, Jaeger KE, Ernst JF.

J Biotechnol. 2015 Oct 10;211:20-30. doi: 10.1016/j.jbiotec.2015.06.423. Epub 2015 Jul 3.


Complete Genome Sequence and Annotation of Corynebacterium singulare DSM 44357, Isolated from a Human Semen Specimen.

Merten M, Brinkrolf K, Albersmeier A, Kutter Y, Rückert C, Tauch A.

Genome Announc. 2015 Mar 26;3(2). pii: e00183-15. doi: 10.1128/genomeA.00183-15.


The DNA methylation landscape of Chinese hamster ovary (CHO) DP-12 cells.

Wippermann A, Rupp O, Brinkrolf K, Hoffrogge R, Noll T.

J Biotechnol. 2015 Apr 10;199:38-46. doi: 10.1016/j.jbiotec.2015.02.014. Epub 2015 Feb 19.


Complete Genome Sequence of Corynebacterium ureicelerivorans DSM 45051, a Lipophilic and Urea-Splitting Isolate from the Blood Culture of a Septicemia Patient.

Tippelt A, Albersmeier A, Brinkrolf K, Rückert C, Fernández-Natal I, Soriano F, Tauch A.

Genome Announc. 2014 Nov 20;2(6). pii: e01211-14. doi: 10.1128/genomeA.01211-14.


Discovery of transcription start sites in the Chinese hamster genome by next-generation RNA sequencing.

Jakobi T, Brinkrolf K, Tauch A, Noll T, Stoye J, Pühler A, Goesmann A.

J Biotechnol. 2014 Nov 20;190:64-75. doi: 10.1016/j.jbiotec.2014.07.437. Epub 2014 Jul 31.


Transcriptome analyses of CHO cells with the next-generation microarray CHO41K: development and validation by analysing the influence of the growth stimulating substance IGF-1 substitute LongR(3.).

Becker J, Timmermann C, Rupp O, Albaum SP, Brinkrolf K, Goesmann A, Pühler A, Tauch A, Noll T.

J Biotechnol. 2014 May 20;178:23-31. doi: 10.1016/j.jbiotec.2014.02.021. Epub 2014 Mar 5.


Complete Genome Sequence of Corynebacterium falsenii DSM 44353 To Study the Evolution of Corynebacterium Cluster 3 Species.

Glaub A, Bomholt C, Gravermann K, Brinkrolf K, Albersmeier A, Rückert C, Tauch A.

Genome Announc. 2014 Mar 6;2(2). pii: e00158-14. doi: 10.1128/genomeA.00158-14.


Construction of a public CHO cell line transcript database using versatile bioinformatics analysis pipelines.

Rupp O, Becker J, Brinkrolf K, Timmermann C, Borth N, Pühler A, Noll T, Goesmann A.

PLoS One. 2014 Jan 10;9(1):e85568. doi: 10.1371/journal.pone.0085568. eCollection 2014.


Whole-Genome Sequence of the Clinical Strain Corynebacterium argentoratense DSM 44202, Isolated from a Human Throat Specimen.

Bomholt C, Glaub A, Gravermann K, Albersmeier A, Brinkrolf K, Rückert C, Tauch A.

Genome Announc. 2013 Oct 3;1(5). pii: e00793-13. doi: 10.1128/genomeA.00793-13.


Chinese hamster genome sequenced from sorted chromosomes.

Brinkrolf K, Rupp O, Laux H, Kollin F, Ernst W, Linke B, Kofler R, Romand S, Hesse F, Budach WE, Galosy S, Müller D, Noll T, Wienberg J, Jostock T, Leonard M, Grillari J, Tauch A, Goesmann A, Helk B, Mott JE, Pühler A, Borth N.

Nat Biotechnol. 2013 Aug;31(8):694-5. doi: 10.1038/nbt.2645. No abstract available.


Draft genome sequence of Wickerhamomyces ciferrii NRRL Y-1031 F-60-10.

Schneider J, Andrea H, Blom J, Jaenicke S, Rückert C, Schorsch C, Szczepanowski R, Farwick M, Goesmann A, Pühler A, Schaffer S, Tauch A, Köhler T, Brinkrolf K.

Eukaryot Cell. 2012 Dec;11(12):1582-3. doi: 10.1128/EC.00258-12.


Draft genome sequence of Turicella otitidis ATCC 51513, isolated from middle ear fluid from a child with otitis media.

Brinkrolf K, Schneider J, Knecht M, Rückert C, Tauch A.

J Bacteriol. 2012 Nov;194(21):5968-9. doi: 10.1128/JB.01412-12.


Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics.

Meleady P, Hoffrogge R, Henry M, Rupp O, Bort JH, Clarke C, Brinkrolf K, Kelly S, Müller B, Doolan P, Hackl M, Beckmann TF, Noll T, Grillari J, Barron N, Pühler A, Clynes M, Borth N.

Biotechnol Bioeng. 2012 Jun;109(6):1386-94. doi: 10.1002/bit.24476. Epub 2012 Mar 2.


Next-generation sequencing of the CHO cell transcriptome.

Becker J, Timmermann C, Jakobi T, Rupp O, Szczepanowski R, Hackl M, Goesmann A, Tauch A, Borth N, Grillari J, Pühler A, Noll T, Brinkrolf K.

BMC Proc. 2011 Nov 22;5 Suppl 8:P6. doi: 10.1186/1753-6561-5-S8-P6. eCollection 2011. No abstract available.


Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines.

Hackl M, Jadhav V, Jakobi T, Rupp O, Brinkrolf K, Goesmann A, Pühler A, Noll T, Borth N, Grillari J.

J Biotechnol. 2012 Apr 15;158(3):151-5. doi: 10.1016/j.jbiotec.2012.01.019. Epub 2012 Jan 25.


Genome sequence of Wickerhamomyces anomalus DSM 6766 reveals genetic basis of biotechnologically important antimicrobial activities.

Schneider J, Rupp O, Trost E, Jaenicke S, Passoth V, Goesmann A, Tauch A, Brinkrolf K.

FEMS Yeast Res. 2012 May;12(3):382-6. doi: 10.1111/j.1567-1364.2012.00791.x. Epub 2012 Feb 23.


Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing.

Becker J, Hackl M, Rupp O, Jakobi T, Schneider J, Szczepanowski R, Bekel T, Borth N, Goesmann A, Grillari J, Kaltschmidt C, Noll T, Pühler A, Tauch A, Brinkrolf K.

J Biotechnol. 2011 Dec 10;156(3):227-35. doi: 10.1016/j.jbiotec.2011.09.014. Epub 2011 Sep 17.


High-quality genome sequence of Pichia pastoris CBS7435.

Küberl A, Schneider J, Thallinger GG, Anderl I, Wibberg D, Hajek T, Jaenicke S, Brinkrolf K, Goesmann A, Szczepanowski R, Pühler A, Schwab H, Glieder A, Pichler H.

J Biotechnol. 2011 Jul 20;154(4):312-20. doi: 10.1016/j.jbiotec.2011.04.014. Epub 2011 May 6.


Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering.

Hackl M, Jakobi T, Blom J, Doppmeier D, Brinkrolf K, Szczepanowski R, Bernhart SH, Höner Zu Siederdissen C, Bort JA, Wieser M, Kunert R, Jeffs S, Hofacker IL, Goesmann A, Pühler A, Borth N, Grillari J.

J Biotechnol. 2011 Apr 20;153(1-2):62-75. doi: 10.1016/j.jbiotec.2011.02.011. Epub 2011 Mar 30.


RAPYD--rapid annotation platform for yeast data.

Schneider J, Blom J, Jaenicke S, Linke B, Brinkrolf K, Neuweger H, Tauch A, Goesmann A.

J Biotechnol. 2011 Aug 20;155(1):118-26. doi: 10.1016/j.jbiotec.2010.10.076. Epub 2010 Oct 30.


The transcriptional regulatory repertoire of Corynebacterium glutamicum: reconstruction of the network controlling pathways involved in lysine and glutamate production.

Brinkrolf K, Schröder J, Pühler A, Tauch A.

J Biotechnol. 2010 Sep 1;149(3):173-82. doi: 10.1016/j.jbiotec.2009.12.004. Epub 2009 Dec 4. Review.


Genetic makeup of the Corynebacterium glutamicum LexA regulon deduced from comparative transcriptomics and in vitro DNA band shift assays.

Jochmann N, Kurze AK, Czaja LF, Brinkrolf K, Brune I, Hüser AT, Hansmeier N, Pühler A, Borovok I, Tauch A.

Microbiology. 2009 May;155(Pt 5):1459-1477. doi: 10.1099/mic.0.025841-0. Epub 2009 Apr 16.


Characterization of the LacI-type transcriptional repressor RbsR controlling ribose transport in Corynebacterium glutamicum ATCC 13032.

Nentwich SS, Brinkrolf K, Gaigalat L, Hüser AT, Rey DA, Mohrbach T, Marin K, Pühler A, Tauch A, Kalinowski J.

Microbiology. 2009 Jan;155(Pt 1):150-164. doi: 10.1099/mic.0.020388-0.


Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids.

Tauch A, Schneider J, Szczepanowski R, Tilker A, Viehoever P, Gartemann KH, Arnold W, Blom J, Brinkrolf K, Brune I, Götker S, Weisshaar B, Goesmann A, Dröge M, Pühler A.

J Biotechnol. 2008 Aug 31;136(1-2):22-30. doi: 10.1016/j.jbiotec.2008.03.004. Epub 2008 Mar 20.


The LacI/GalR family transcriptional regulator UriR negatively controls uridine utilization of Corynebacterium glutamicum by binding to catabolite-responsive element (cre)-like sequences.

Brinkrolf K, Plöger S, Solle S, Brune I, Nentwich SS, Hüser AT, Kalinowski J, Pühler A, Tauch A.

Microbiology. 2008 Apr;154(Pt 4):1068-1081. doi: 10.1099/mic.0.2007/014001-0.


The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing.

Tauch A, Trost E, Tilker A, Ludewig U, Schneiker S, Goesmann A, Arnold W, Bekel T, Brinkrolf K, Brune I, Götker S, Kalinowski J, Kamp PB, Lobo FP, Viehoever P, Weisshaar B, Soriano F, Dröge M, Pühler A.

J Biotechnol. 2008 Aug 31;136(1-2):11-21. doi: 10.1016/j.jbiotec.2008.02.009. Epub 2008 Mar 10.


The IclR-type transcriptional repressor LtbR regulates the expression of leucine and tryptophan biosynthesis genes in the amino acid producer Corynebacterium glutamicum.

Brune I, Jochmann N, Brinkrolf K, Hüser AT, Gerstmeir R, Eikmanns BJ, Kalinowski J, Pühler A, Tauch A.

J Bacteriol. 2007 Apr;189(7):2720-33. Epub 2007 Jan 26.


CoryneRegNet 3.0--an interactive systems biology platform for the analysis of gene regulatory networks in corynebacteria and Escherichia coli.

Baumbach J, Wittkop T, Rademacher K, Rahmann S, Brinkrolf K, Tauch A.

J Biotechnol. 2007 Apr 30;129(2):279-89. Epub 2006 Dec 20.


The transcriptional regulatory network of the amino acid producer Corynebacterium glutamicum.

Brinkrolf K, Brune I, Tauch A.

J Biotechnol. 2007 Apr 30;129(2):191-211. Epub 2006 Dec 20. Review.


Transcriptional regulation of catabolic pathways for aromatic compounds in Corynebacterium glutamicum.

Brinkrolf K, Brune I, Tauch A.

Genet Mol Res. 2006 Dec 7;5(4):773-89. Review.


CoryneRegNet: an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks.

Baumbach J, Brinkrolf K, Czaja LF, Rahmann S, Tauch A.

BMC Genomics. 2006 Feb 14;7:24.

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