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Items: 1 to 50 of 225

1.

Staphylococcus saccharolyticus Isolated From Blood Cultures and Prosthetic Joint Infections Exhibits Excessive Genome Decay.

Brüggemann H, Poehlein A, Brzuszkiewicz E, Scavenius C, Enghild JJ, Al-Zeer MA, Brinkmann V, Jensen A, Söderquist B.

Front Microbiol. 2019 Mar 12;10:478. doi: 10.3389/fmicb.2019.00478. eCollection 2019.

2.

Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation.

Kessler M, Hoffmann K, Fritsche K, Brinkmann V, Mollenkopf HJ, Thieck O, Teixeira da Costa AR, Braicu EI, Sehouli J, Mangler M, Berger H, Meyer TF.

Nat Commun. 2019 Mar 18;10(1):1194. doi: 10.1038/s41467-019-09144-7.

3.

Dnase1-deficient mice spontaneously develop a systemic lupus erythematosus-like disease.

Kenny EF, Raupach B, Abu Abed U, Brinkmann V, Zychlinsky A.

Eur J Immunol. 2019 Apr;49(4):590-599. doi: 10.1002/eji.201847875. Epub 2019 Feb 21.

PMID:
30758851
4.

Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis.

Weckbach LT, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, Pick R, Salvermoser M, Czermak T, Pircher J, Sorrelle N, Migliorini M, Strickland DK, Klingel K, Brinkmann V, Abu Abed U, Eriksson U, Massberg S, Brunner S, Walzog B.

J Exp Med. 2019 Feb 4;216(2):350-368. doi: 10.1084/jem.20181102. Epub 2019 Jan 15.

PMID:
30647120
5.

Genomic features of the Helicobacter pylori strain PMSS1 and its virulence attributes as deduced from its in vivo colonisation patterns.

Dyer V, Brüggemann H, Sörensen M, Kühl AA, Hoffman K, Brinkmann V, Reines MDM, Zimmerman S, Meyer TF, Koch M.

Mol Microbiol. 2018 Dec;110(5):761-776. doi: 10.1111/mmi.14123. Epub 2018 Oct 25.

PMID:
30230643
6.

Non-competitive resource exploitation within mosquito shapes within-host malaria infectivity and virulence.

Costa G, Gildenhard M, Eldering M, Lindquist RL, Hauser AE, Sauerwein R, Goosmann C, Brinkmann V, Carrillo-Bustamante P, Levashina EA.

Nat Commun. 2018 Aug 27;9(1):3474. doi: 10.1038/s41467-018-05893-z.

7.

Unbiased classification of mosquito blood cells by single-cell genomics and high-content imaging.

Severo MS, Landry JJM, Lindquist RL, Goosmann C, Brinkmann V, Collier P, Hauser AE, Benes V, Henriksson J, Teichmann SA, Levashina EA.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):E7568-E7577. doi: 10.1073/pnas.1803062115. Epub 2018 Jul 23.

8.

Neutrophil Extracellular Traps in the Second Decade.

Brinkmann V.

J Innate Immun. 2018;10(5-6):414-421. doi: 10.1159/000489829. Epub 2018 Jun 15. Review.

9.

Influence of varus/valgus positioning of the Nanos® and Metha® short-stemmed prostheses on stress shielding of metaphyseal bone.

Brinkmann V, Radetzki F, Gutteck N, Delank S, Zeh A.

Acta Orthop Belg. 2017 Mar;83(1):57-66.

PMID:
29322896
10.

Pan-genome analysis of the genus Finegoldia identifies two distinct clades, strain-specific heterogeneity, and putative virulence factors.

Brüggemann H, Jensen A, Nazipi S, Aslan H, Meyer RL, Poehlein A, Brzuszkiewicz E, Al-Zeer MA, Brinkmann V, Söderquist B.

Sci Rep. 2018 Jan 10;8(1):266. doi: 10.1038/s41598-017-18661-8.

11.

Efficacy Testing of H56 cDNA Tattoo Immunization against Tuberculosis in a Mouse Model.

Platteel ACM, Nieuwenhuizen NE, Domaszewska T, Schürer S, Zedler U, Brinkmann V, Sijts AJAM, Kaufmann SHE.

Front Immunol. 2017 Dec 11;8:1744. doi: 10.3389/fimmu.2017.01744. eCollection 2017.

12.

The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy.

Pei G, Buijze H, Liu H, Moura-Alves P, Goosmann C, Brinkmann V, Kawabe H, Dorhoi A, Kaufmann SHE.

Autophagy. 2017;13(12):2041-2055. doi: 10.1080/15548627.2017.1376160. Epub 2017 Dec 17.

13.

Prevalence of Flp Pili-Encoding Plasmids in Cutibacterium acnes Isolates Obtained from Prostatic Tissue.

Davidsson S, Carlsson J, Mölling P, Gashi N, Andrén O, Andersson SO, Brzuszkiewicz E, Poehlein A, Al-Zeer MA, Brinkmann V, Scavenius C, Nazipi S, Söderquist B, Brüggemann H.

Front Microbiol. 2017 Nov 16;8:2241. doi: 10.3389/fmicb.2017.02241. eCollection 2017.

14.

Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps.

Amulic B, Knackstedt SL, Abu Abed U, Deigendesch N, Harbort CJ, Caffrey BE, Brinkmann V, Heppner FL, Hinds PW, Zychlinsky A.

Dev Cell. 2017 Nov 20;43(4):449-462.e5. doi: 10.1016/j.devcel.2017.10.013. Epub 2017 Nov 2.

15.

Mycobacterium tuberculosis infection modulates adipose tissue biology.

Beigier-Bompadre M, Montagna GN, Kühl AA, Lozza L, Weiner J 3rd, Kupz A, Vogelzang A, Mollenkopf HJ, Löwe D, Bandermann S, Dorhoi A, Brinkmann V, Matuschewski K, Kaufmann SHE.

PLoS Pathog. 2017 Oct 17;13(10):e1006676. doi: 10.1371/journal.ppat.1006676. eCollection 2017 Oct.

16.

ALPK1- and TIFA-Dependent Innate Immune Response Triggered by the Helicobacter pylori Type IV Secretion System.

Zimmermann S, Pfannkuch L, Al-Zeer MA, Bartfeld S, Koch M, Liu J, Rechner C, Soerensen M, Sokolova O, Zamyatina A, Kosma P, Mäurer AP, Glowinski F, Pleissner KP, Schmid M, Brinkmann V, Karlas A, Naumann M, Rother M, Machuy N, Meyer TF.

Cell Rep. 2017 Sep 5;20(10):2384-2395. doi: 10.1016/j.celrep.2017.08.039.

17.

PMK-1 p38 MAPK promotes cadmium stress resistance, the expression of SKN-1/Nrf and DAF-16 target genes, and protein biosynthesis in Caenorhabditis elegans.

Keshet A, Mertenskötter A, Winter SA, Brinkmann V, Dölling R, Paul RJ.

Mol Genet Genomics. 2017 Dec;292(6):1341-1361. doi: 10.1007/s00438-017-1351-z. Epub 2017 Aug 1.

18.

Diverse stimuli engage different neutrophil extracellular trap pathways.

Kenny EF, Herzig A, Krüger R, Muth A, Mondal S, Thompson PR, Brinkmann V, Bernuth HV, Zychlinsky A.

Elife. 2017 Jun 2;6. pii: e24437. doi: 10.7554/eLife.24437.

19.

Neutrophil alterations in pregnancy-associated malaria and induction of neutrophil chemotaxis by Plasmodium falciparum.

Boström S, Schmiegelow C, Abu Abed U, Minja DTR, Lusingu J, Brinkmann V, Honkpehedji YJ, Loembe MM, Adegnika AA, Mordmüller B, Troye-Blomberg M, Amulic B.

Parasite Immunol. 2017 Jun;39(6). doi: 10.1111/pim.12433.

20.

Optogenetic monitoring identifies phosphatidylthreonine-regulated calcium homeostasis in Toxoplasma gondii.

Kuchipudi A, Arroyo-Olarte RD, Hoffmann F, Brinkmann V, Gupta N.

Microb Cell. 2016 May 2;3(5):215-223. doi: 10.15698/mic2016.05.500.

21.

Immunodetection of NETs in Paraffin-Embedded Tissue.

Brinkmann V, Abu Abed U, Goosmann C, Zychlinsky A.

Front Immunol. 2016 Nov 22;7:513. eCollection 2016.

22.

Comparative Plasmodium gene overexpression reveals distinct perturbation of sporozoite transmission by profilin.

Sato Y, Hliscs M, Dunst J, Goosmann C, Brinkmann V, Montagna GN, Matuschewski K.

Mol Biol Cell. 2016 Jul 15;27(14):2234-44. doi: 10.1091/mbc.E15-10-0734. Epub 2016 May 25.

23.

Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer's disease.

Aytan N, Choi JK, Carreras I, Brinkmann V, Kowall NW, Jenkins BG, Dedeoglu A.

Sci Rep. 2016 Apr 27;6:24939. doi: 10.1038/srep24939.

24.

Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells.

Wörmann X, Lesch M, Welke RW, Okonechnikov K, Abdurishid M, Sieben C, Geissner A, Brinkmann V, Kastner M, Karner A, Zhu R, Hinterdorfer P, Anish C, Seeberger PH, Herrmann A, Meyer TF, Karlas A.

Virology. 2016 May;492:118-29. doi: 10.1016/j.virol.2016.02.002. Epub 2016 Feb 23.

25.

The aryl hydrocarbon receptor promotes aging phenotypes across species.

Eckers A, Jakob S, Heiss C, Haarmann-Stemmann T, Goy C, Brinkmann V, Cortese-Krott MM, Sansone R, Esser C, Ale-Agha N, Altschmied J, Ventura N, Haendeler J.

Sci Rep. 2016 Jan 21;6:19618. doi: 10.1038/srep19618.

26.

The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids.

Kessler M, Hoffmann K, Brinkmann V, Thieck O, Jackisch S, Toelle B, Berger H, Mollenkopf HJ, Mangler M, Sehouli J, Fotopoulou C, Meyer TF.

Nat Commun. 2015 Dec 8;6:8989. doi: 10.1038/ncomms9989.

27.

Tissue Distribution Dynamics of Human NK Cells Inferred from Peripheral Blood Depletion Kinetics after Sphingosine-1-Phosphate Receptor Blockade.

Mehling M, Burgener AV, Brinkmann V, Bantug GR, Dimeloe S, Hoenger G, Kappos L, Hess C.

Scand J Immunol. 2015 Nov;82(5):460-6. doi: 10.1111/sji.12347.

28.

The Plasmodium berghei translocon of exported proteins reveals spatiotemporal dynamics of tubular extensions.

Matz JM, Goosmann C, Brinkmann V, Grützke J, Ingmundson A, Matuschewski K, Kooij TW.

Sci Rep. 2015 Jul 29;5:12532. doi: 10.1038/srep12532.

29.

Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity.

Xu D, Olson J, Cole JN, van Wijk XM, Brinkmann V, Zychlinsky A, Nizet V, Esko JD, Chang YC.

Infect Immun. 2015 Sep;83(9):3648-56. doi: 10.1128/IAI.00545-15. Epub 2015 Jul 6.

30.

Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans.

Schiavi A, Maglioni S, Palikaras K, Shaik A, Strappazzon F, Brinkmann V, Torgovnick A, Castelein N, De Henau S, Braeckman BP, Cecconi F, Tavernarakis N, Ventura N.

Curr Biol. 2015 Jul 20;25(14):1810-22. doi: 10.1016/j.cub.2015.05.059. Epub 2015 Jul 2.

31.

A prospective randomized radiographic and dual-energy X-ray absorptiometric study of migration and bone remodeling after implantation of two modern short-stemmed femoral prostheses.

Brinkmann V, Radetzki F, Delank KS, Wohlrab D, Zeh A.

J Orthop Traumatol. 2015 Sep;16(3):237-43. doi: 10.1007/s10195-015-0335-1. Epub 2015 Feb 11.

32.

Cardiac and vascular effects of fingolimod: mechanistic basis and clinical implications.

Camm J, Hla T, Bakshi R, Brinkmann V.

Am Heart J. 2014 Nov;168(5):632-44. doi: 10.1016/j.ahj.2014.06.028. Epub 2014 Jul 11. Review.

33.

Chlamydia infection depends on a functional MDM2-p53 axis.

González E, Rother M, Kerr MC, Al-Zeer MA, Abu-Lubad M, Kessler M, Brinkmann V, Loewer A, Meyer TF.

Nat Commun. 2014 Nov 13;5:5201. doi: 10.1038/ncomms6201.

34.

Chlamydia trachomatis remodels stable microtubules to coordinate Golgi stack recruitment to the chlamydial inclusion surface.

Al-Zeer MA, Al-Younes HM, Kerr M, Abu-Lubad M, Gonzalez E, Brinkmann V, Meyer TF.

Mol Microbiol. 2014 Dec;94(6):1285-97. doi: 10.1111/mmi.12829. Epub 2014 Nov 3.

35.

Lung-residing myeloid-derived suppressors display dual functionality in murine pulmonary tuberculosis.

Knaul JK, Jörg S, Oberbeck-Mueller D, Heinemann E, Scheuermann L, Brinkmann V, Mollenkopf HJ, Yeremeev V, Kaufmann SH, Dorhoi A.

Am J Respir Crit Care Med. 2014 Nov 1;190(9):1053-66. doi: 10.1164/rccm.201405-0828OC.

PMID:
25275852
36.

AhR sensing of bacterial pigments regulates antibacterial defence.

Moura-Alves P, Faé K, Houthuys E, Dorhoi A, Kreuchwig A, Furkert J, Barison N, Diehl A, Munder A, Constant P, Skrahina T, Guhlich-Bornhof U, Klemm M, Koehler AB, Bandermann S, Goosmann C, Mollenkopf HJ, Hurwitz R, Brinkmann V, Fillatreau S, Daffe M, Tümmler B, Kolbe M, Oschkinat H, Krause G, Kaufmann SH.

Nature. 2014 Aug 28;512(7515):387-92. doi: 10.1038/nature13684. Epub 2014 Aug 13.

PMID:
25119038
37.

Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics.

Dorhoi A, Yeremeev V, Nouailles G, Weiner J 3rd, Jörg S, Heinemann E, Oberbeck-Müller D, Knaul JK, Vogelzang A, Reece ST, Hahnke K, Mollenkopf HJ, Brinkmann V, Kaufmann SH.

Eur J Immunol. 2014 Aug;44(8):2380-93. doi: 10.1002/eji.201344219. Epub 2014 Jun 24.

38.

IcsA is a Shigella flexneri adhesin regulated by the type III secretion system and required for pathogenesis.

Brotcke Zumsteg A, Goosmann C, Brinkmann V, Morona R, Zychlinsky A.

Cell Host Microbe. 2014 Apr 9;15(4):435-45. doi: 10.1016/j.chom.2014.03.001.

39.

[Morbid obesity in total knee arthroplasty: a critical case review].

Brinkmann V, Wohlrab D, Esmer E, Juch F, Delank KS, Freche S.

Dtsch Med Wochenschr. 2014 Apr;139(15):774-7. doi: 10.1055/s-0034-1369909. Epub 2014 Apr 1. German.

PMID:
24691690
40.

The spatiotemporal dynamics and membranous features of the Plasmodium liver stage tubovesicular network.

Grützke J, Rindte K, Goosmann C, Silvie O, Rauch C, Heuer D, Lehmann MJ, Mueller AK, Brinkmann V, Matuschewski K, Ingmundson A.

Traffic. 2014 Apr;15(4):362-82. doi: 10.1111/tra.12151. Epub 2014 Feb 13.

41.

Second generation S1P pathway modulators: research strategies and clinical developments.

Bigaud M, Guerini D, Billich A, Bassilana F, Brinkmann V.

Biochim Biophys Acta. 2014 May;1841(5):745-58. doi: 10.1016/j.bbalip.2013.11.001. Epub 2013 Nov 12. Review.

PMID:
24239768
42.

Comparative genomics reveals distinct host-interacting traits of three major human-associated propionibacteria.

Mak TN, Schmid M, Brzuszkiewicz E, Zeng G, Meyer R, Sfanos KS, Brinkmann V, Meyer TF, Brüggemann H.

BMC Genomics. 2013 Sep 22;14:640. doi: 10.1186/1471-2164-14-640.

43.

Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours.

Wend P, Fang L, Zhu Q, Schipper JH, Loddenkemper C, Kosel F, Brinkmann V, Eckert K, Hindersin S, Holland JD, Lehr S, Kahn M, Ziebold U, Birchmeier W.

EMBO J. 2013 Jul 17;32(14):1977-89. doi: 10.1038/emboj.2013.127. Epub 2013 Jun 4.

44.

A proposed role for neutrophil extracellular traps in cancer immunoediting.

Berger-Achituv S, Brinkmann V, Abed UA, Kühn LI, Ben-Ezra J, Elhasid R, Zychlinsky A.

Front Immunol. 2013 Mar 6;4:48. doi: 10.3389/fimmu.2013.00048. eCollection 2013.

45.

Homing frequency of human T cells inferred from peripheral blood depletion kinetics after sphingosine-1-phosphate receptor blockade.

Mehling M, Brinkmann V, Burgener AV, Gubser P, Luster AD, Kappos L, Hess C.

J Allergy Clin Immunol. 2013 May;131(5):1440-3.e7. doi: 10.1016/j.jaci.2012.12.1520. Epub 2013 Feb 21. No abstract available.

PMID:
23434284
46.

Automatic quantification of in vitro NET formation.

Brinkmann V, Goosmann C, Kühn LI, Zychlinsky A.

Front Immunol. 2013 Jan 9;3:413. doi: 10.3389/fimmu.2012.00413. eCollection 2012.

47.

A potent and selective S1P(1) antagonist with efficacy in experimental autoimmune encephalomyelitis.

Quancard J, Bollbuck B, Janser P, Angst D, Berst F, Buehlmayer P, Streiff M, Beerli C, Brinkmann V, Guerini D, Smith PA, Seabrook TJ, Traebert M, Seuwen K, Hersperger R, Bruns C, Bassilana F, Bigaud M.

Chem Biol. 2012 Sep 21;19(9):1142-51. doi: 10.1016/j.chembiol.2012.07.016.

48.

Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development.

Jung B, Obinata H, Galvani S, Mendelson K, Ding BS, Skoura A, Kinzel B, Brinkmann V, Rafii S, Evans T, Hla T.

Dev Cell. 2012 Sep 11;23(3):600-10. doi: 10.1016/j.devcel.2012.07.015.

49.

Spontaneous formation of IpaB ion channels in host cell membranes reveals how Shigella induces pyroptosis in macrophages.

Senerovic L, Tsunoda SP, Goosmann C, Brinkmann V, Zychlinsky A, Meissner F, Kolbe M.

Cell Death Dis. 2012 Sep 6;3:e384. doi: 10.1038/cddis.2012.124.

50.

Neutrophil extracellular traps: is immunity the second function of chromatin?

Brinkmann V, Zychlinsky A.

J Cell Biol. 2012 Sep 3;198(5):773-83. doi: 10.1083/jcb.201203170. Review.

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