Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 290


Parasite-microbe-host interactions and cancer risk.

Dheilly NM, Ewald PW, Brindley PJ, Fichorova RN, Thomas F.

PLoS Pathog. 2019 Aug 15;15(8):e1007912. doi: 10.1371/journal.ppat.1007912. eCollection 2019 Aug. No abstract available.


Differential responses of epithelial cells from urinary and biliary tract to eggs of Schistosoma haematobium and S. mansoni.

Nacif-Pimenta R, da Silva Orfanó A, Mosley IA, Karinshak SE, Ishida K, Mann VH, Coelho PMZ, da Costa JMC, Hsieh MH, Brindley PJ, Rinaldi G.

Sci Rep. 2019 Jul 24;9(1):10731. doi: 10.1038/s41598-019-46917-y.


Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics.

Tyagi R, Elfawal MA, Wildman SA, Helander J, Bulman CA, Sakanari J, Rosa BA, Brindley PJ, Janetka JW, Aroian RV, Mitreva M.

Sci Rep. 2019 Jun 24;9(1):9085. doi: 10.1038/s41598-019-45548-7.


The antioxidants resveratrol and N-acetylcysteine enhance anthelmintic activity of praziquantel and artesunate against Schistosoma mansoni.

Gouveia MJ, Brindley PJ, Azevedo C, Gärtner F, da Costa JMC, Vale N.

Parasit Vectors. 2019 Jun 20;12(1):309. doi: 10.1186/s13071-019-3566-9.


Vaccination of hamsters with Opisthorchis viverrini extracellular vesicles and vesicle-derived recombinant tetraspanins induces antibodies that block vesicle uptake by cholangiocytes and reduce parasite burden after challenge infection.

Chaiyadet S, Sotillo J, Krueajampa W, Thongsen S, Brindley PJ, Sripa B, Loukas A, Laha T.

PLoS Negl Trop Dis. 2019 May 28;13(5):e0007450. doi: 10.1371/journal.pntd.0007450. eCollection 2019 May.


Diagnosis of feline filariasis assisted by a novel semi-automated microfluidic device in combination with high resolution melting real-time PCR.

Phuakrod A, Sripumkhai W, Jeamsaksiri W, Pattamang P, Juntasaro E, Thienthong T, Foongladda S, Brindley PJ, Wongkamchai S.

Parasit Vectors. 2019 Apr 8;12(1):159. doi: 10.1186/s13071-019-3421-z.


Combination Anthelmintic/Antioxidant Activity Against Schistosoma Mansoni.

Gouveia MJ, Brindley PJ, Rinaldi G, Gärtner F, Correia da Costa JM, Vale N.

Biomolecules. 2019 Feb 5;9(2). pii: E54. doi: 10.3390/biom9020054.


Programmed knockout mutation of liver fluke granulin attenuates virulence of infection-induced hepatobiliary morbidity.

Arunsan P, Ittiprasert W, Smout MJ, Cochran CJ, Mann VH, Chaiyadet S, Karinshak SE, Sripa B, Young ND, Sotillo J, Loukas A, Brindley PJ, Laha T.

Elife. 2019 Jan 15;8. pii: e41463. doi: 10.7554/eLife.41463.


Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni.

Ittiprasert W, Mann VH, Karinshak SE, Coghlan A, Rinaldi G, Sankaranarayanan G, Chaidee A, Tanno T, Kumkhaek C, Prangtaworn P, Mentink-Kane MM, Cochran CJ, Driguez P, Holroyd N, Tracey A, Rodpai R, Everts B, Hokke CH, Hoffmann KF, Berriman M, Brindley PJ.

Elife. 2019 Jan 15;8. pii: e41337. doi: 10.7554/eLife.41337.


Helminth Microbiomes - A Hidden Treasure Trove?

Jenkins TP, Brindley PJ, Gasser RB, Cantacessi C.

Trends Parasitol. 2019 Jan;35(1):13-22. doi: 10.1016/ Epub 2018 Nov 29. Review.


Update on Pathogenesis of Opisthorchiasis and Cholangiocarcinoma.

Sripa B, Tangkawattana S, Brindley PJ.

Adv Parasitol. 2018;102:97-113. doi: 10.1016/bs.apar.2018.10.001. Epub 2018 Oct 22. Review.


RNA Interference as an Approach to Functional Genomics Genetic Manipulation of Opisthorchis viverrini.

Laha T, Brindley PJ, Suyapoh W, Suttiprapa S.

Adv Parasitol. 2018;102:25-43. doi: 10.1016/bs.apar.2018.06.001. Epub 2018 Jul 18. Review.


Opisthorchiasis and the Microbiome.

Saltykova IV, Petrov VA, Brindley PJ.

Adv Parasitol. 2018;102:1-23. doi: 10.1016/bs.apar.2018.07.001. Epub 2018 Aug 17. Review.


Granulin Expression in Hamsters during Opisthorchis viverrini Infection-Induced Cholangiocarcinogenesis

Upontain S, Sereerak P, Laha T, Sripa B, Tangkawatana P, Brindley PJ, Tangkawatana S.

Asian Pac J Cancer Prev. 2018 Sep 26;19(9):2437-2445.


Structural Variants of a Liver Fluke Derived Granulin Peptide Potently Stimulate Wound Healing.

Dastpeyman M, Bansal PS, Wilson D, Sotillo J, Brindley PJ, Loukas A, Smout MJ, Daly NL.

J Med Chem. 2018 Oct 11;61(19):8746-8753. doi: 10.1021/acs.jmedchem.8b00898. Epub 2018 Sep 24.


Schistosoma mansoni infection is associated with quantitative and qualitative modifications of the mammalian intestinal microbiota.

Jenkins TP, Peachey LE, Ajami NJ, MacDonald AS, Hsieh MH, Brindley PJ, Cantacessi C, Rinaldi G.

Sci Rep. 2018 Aug 13;8(1):12072. doi: 10.1038/s41598-018-30412-x.


The snail Biomphalaria glabrata as a model to interrogate the molecular basis of complex human diseases.

Bridger JM, Brindley PJ, Knight M.

PLoS Negl Trop Dis. 2018 Aug 9;12(8):e0006552. doi: 10.1371/journal.pntd.0006552. eCollection 2018 Aug. No abstract available.


Co-occurrence of opisthorchiasis and diabetes exacerbates morbidity of the hepatobiliary tract disease.

Chaidee A, Onsurathum S, Intuyod K, Pannangpetch P, Pongchaiyakul C, Pinlaor P, Pairojkul C, Ittiprasert W, Cochran CJ, Mann VH, Brindley PJ, Pinlaor S.

PLoS Negl Trop Dis. 2018 Jun 28;12(6):e0006611. doi: 10.1371/journal.pntd.0006611. eCollection 2018 Jun.


The small RNA complement of adult Schistosoma haematobium.

Stroehlein AJ, Young ND, Korhonen PK, Hall RS, Jex AR, Webster BL, Rollinson D, Brindley PJ, Gasser RB.

PLoS Negl Trop Dis. 2018 May 29;12(5):e0006535. doi: 10.1371/journal.pntd.0006535. eCollection 2018 May.


Developmental Sensitivity in Schistosoma mansoni to Puromycin To Establish Drug Selection of Transgenic Schistosomes.

Yan HB, Smout MJ, Ju C, Folley AE, Skinner DE, Mann VH, Loukas A, Hu W, Brindley PJ, Rinaldi G.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e02568-17. doi: 10.1128/AAC.02568-17. Print 2018 Aug.


Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics.

Tyagi R, Maddirala AR, Elfawal M, Fischer C, Bulman CA, Rosa BA, Gao X, Chugani R, Zhou M, Helander J, Brindley PJ, Tseng CC, Greig IR, Sakanari J, Wildman SA, Aroian R, Janetka JW, Mitreva M.

ACS Infect Dis. 2018 Jul 13;4(7):1130-1145. doi: 10.1021/acsinfecdis.8b00090. Epub 2018 May 14.


Granulin Secreted by the Food-Borne Liver Fluke Opisthorchis viverrini Promotes Angiogenesis in Human Endothelial Cells.

Haugen B, Karinshak SE, Mann VH, Popratiloff A, Loukas A, Brindley PJ, Smout MJ.

Front Med (Lausanne). 2018 Feb 16;5:30. doi: 10.3389/fmed.2018.00030. eCollection 2018.


Drug Repurposing for Schistosomiasis: Combinations of Drugs or Biomolecules.

Gouveia MJ, Brindley PJ, Gärtner F, Costa JMCD, Vale N.

Pharmaceuticals (Basel). 2018 Feb 5;11(1). pii: E15. doi: 10.3390/ph11010015. Review.


Expression, purification and characterization of two leucine aminopeptidases of the blood fluke, Schistosoma mansoni.

Maggioli G, Rinaldi G, Giaudrone I, Berasain P, Tort JF, Brindley PJ, Carmona C.

Mol Biochem Parasitol. 2018 Jan;219:17-23. doi: 10.1016/j.molbiopara.2017.11.006. Epub 2017 Nov 21.


Suppression of mRNAs encoding CD63 family tetraspanins from the carcinogenic liver fluke Opisthorchis viverrini results in distinct tegument phenotypes.

Chaiyadet S, Krueajampa W, Hipkaeo W, Plosan Y, Piratae S, Sotillo J, Smout M, Sripa B, Brindley PJ, Loukas A, Laha T.

Sci Rep. 2017 Oct 30;7(1):14342. doi: 10.1038/s41598-017-13527-5.


Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model.

Gouveia MJ, Pakharukova MY, Laha T, Sripa B, Maksimova GA, Rinaldi G, Brindley PJ, Mordvinov VA, Amaro T, Santos LL, Costa JMCD, Vale N.

Carcinogenesis. 2017 Sep 1;38(9):929-937. doi: 10.1093/carcin/bgx042.


Parasite Microbiome Project: Systematic Investigation of Microbiome Dynamics within and across Parasite-Host Interactions.

Dheilly NM, Bolnick D, Bordenstein S, Brindley PJ, Figuères C, Holmes EC, Martínez Martínez J, Phillips AJ, Poulin R, Rosario K.

mSystems. 2017 Jul 18;2(4). pii: e00050-17. doi: 10.1128/mSystems.00050-17. eCollection 2017 Jul-Aug.


Helminth infection-induced malignancy.

Brindley PJ, Loukas A.

PLoS Pathog. 2017 Jul 27;13(7):e1006393. doi: 10.1371/journal.ppat.1006393. eCollection 2017 Jul. Review. No abstract available.


Subsets of Inflammatory Cytokine Gene Polymorphisms are Associated with Risk of Carcinogenic Liver Fluke Opisthorchis viverrini-Associated Advanced Periductal Fibrosis and Cholangiocarcinoma.

Surapaitoon A, Suttiprapa S, Mairiang E, Khuntikeo N, Pairojkul C, Bethony J, Brindley PJ, Sripa B.

Korean J Parasitol. 2017 Jun;55(3):295-304. doi: 10.3347/kjp.2017.55.3.295. Epub 2017 Jun 30.


Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold.

Bansal PS, Smout MJ, Wilson D, Cobos Caceres C, Dastpeyman M, Sotillo J, Seifert J, Brindley PJ, Loukas A, Daly NL.

J Med Chem. 2017 May 25;60(10):4258-4266. doi: 10.1021/acs.jmedchem.7b00047. Epub 2017 May 3.


The role of estradiol metabolism in urogenital schistosomiasis-induced bladder cancer.

Vale N, Gouveia MJ, Rinaldi G, Santos J, Santos LL, Brindley PJ, da Costa JM.

Tumour Biol. 2017 Mar;39(3):1010428317692247. doi: 10.1177/1010428317692247. Review.


Dynamic transcriptomes identify biogenic amines and insect-like hormonal regulation for mediating reproduction in Schistosoma japonicum.

Wang J, Yu Y, Shen H, Qing T, Zheng Y, Li Q, Mo X, Wang S, Li N, Chai R, Xu B, Liu M, Brindley PJ, McManus DP, Feng Z, Shi L, Hu W.

Nat Commun. 2017 Mar 13;8:14693. doi: 10.1038/ncomms14693.


Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance.

Vale N, Gouveia MJ, Rinaldi G, Brindley PJ, Gärtner F, Correia da Costa JM.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02582-16. doi: 10.1128/AAC.02582-16. Print 2017 May. Review.


Elevated prevalence of Helicobacter species and virulence factors in opisthorchiasis and associated hepatobiliary disease.

Deenonpoe R, Mairiang E, Mairiang P, Pairojkul C, Chamgramol Y, Rinaldi G, Loukas A, Brindley PJ, Sripa B.

Sci Rep. 2017 Feb 15;7:42744. doi: 10.1038/srep42744.


Genomes of Fasciola hepatica from the Americas Reveal Colonization with Neorickettsia Endobacteria Related to the Agents of Potomac Horse and Human Sennetsu Fevers.

McNulty SN, Tort JF, Rinaldi G, Fischer K, Rosa BA, Smircich P, Fontenla S, Choi YJ, Tyagi R, Hallsworth-Pepin K, Mann VH, Kammili L, Latham PS, Dell'Oca N, Dominguez F, Carmona C, Fischer PU, Brindley PJ, Mitreva M.

PLoS Genet. 2017 Jan 6;13(1):e1006537. doi: 10.1371/journal.pgen.1006537. eCollection 2017 Jan.


Parasite Infection, Carcinogenesis and Human Malignancy.

van Tong H, Brindley PJ, Meyer CG, Velavan TP.

EBioMedicine. 2017 Feb;15:12-23. doi: 10.1016/j.ebiom.2016.11.034. Epub 2016 Dec 2. Review.


Co-infections with liver fluke and Helicobacter species: A paradigm change in pathogenesis of opisthorchiasis and cholangiocarcinoma?

Sripa B, Deenonpoe R, Brindley PJ.

Parasitol Int. 2017 Aug;66(4):383-389. doi: 10.1016/j.parint.2016.11.016. Epub 2016 Dec 3. Review.


HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni.

Suttiprapa S, Rinaldi G, Tsai IJ, Mann VH, Dubrovsky L, Yan HB, Holroyd N, Huckvale T, Durrant C, Protasio AV, Pushkarsky T, Iordanskiy S, Berriman M, Bukrinsky MI, Brindley PJ.

PLoS Pathog. 2016 Oct 20;12(10):e1005931. doi: 10.1371/journal.ppat.1005931. eCollection 2016 Oct.


Biliary Microbiota, Gallstone Disease and Infection with Opisthorchis felineus.

Saltykova IV, Petrov VA, Logacheva MD, Ivanova PG, Merzlikin NV, Sazonov AE, Ogorodova LM, Brindley PJ.

PLoS Negl Trop Dis. 2016 Jul 22;10(7):e0004809. doi: 10.1371/journal.pntd.0004809. eCollection 2016 Jul.


Decreased risk of cholangiocarcinogenesis following repeated cycles of Opisthorchis viverrini infection-praziquantel treatment: Magnetic Resonance Imaging (MRI) and histopathological study in a hamster model.

Hanpanich P, Laha T, Sripa B, Mairiang E, Sereerak P, Upontain S, Tangkawattana P, Brindley PJ, Tangkawattana S.

Parasitol Int. 2017 Aug;66(4):464-470. doi: 10.1016/j.parint.2016.04.012. Epub 2016 Apr 30.


Chicken IgY-based coproantigen capture ELISA for diagnosis of human opisthorchiasis.

Teimoori S, Arimatsu Y, Laha T, Kaewkes S, Sereerak P, Sripa M, Tangkawattana S, Brindley PJ, Sripa B.

Parasitol Int. 2017 Aug;66(4):443-447. doi: 10.1016/j.parint.2015.10.011. Epub 2016 Apr 29.


Insight into the molecular basis of Schistosoma haematobium-induced bladder cancer through urine proteomics.

Bernardo C, Cunha MC, Santos JH, da Costa JM, Brindley PJ, Lopes C, Amado F, Ferreira R, Vitorino R, Santos LL.

Tumour Biol. 2016 Aug;37(8):11279-87. doi: 10.1007/s13277-016-4997-y. Epub 2016 Mar 7.


Carbonyl stress phenomena during chronic infection with Opisthorchis felineus.

Saltykova IV, Ogorodova LM, Ivanov VV, Bogdanov AO, Gereng EA, Perina EA, Brindley PJ, Sazonov AE.

Parasitol Int. 2017 Aug;66(4):453-457. doi: 10.1016/j.parint.2016.01.002. Epub 2016 Jan 8.


Functional Analysis of the Unique Cytochrome P450 of the Liver Fluke Opisthorchis felineus.

Pakharukova MY, Vavilin VA, Sripa B, Laha T, Brindley PJ, Mordvinov VA.

PLoS Negl Trop Dis. 2015 Dec 1;9(12):e0004258. doi: 10.1371/journal.pntd.0004258. eCollection 2015 Dec.


Why does infection with some helminths cause cancer?

Brindley PJ, da Costa JM, Sripa B.

Trends Cancer. 2015 Nov 1;1(3):174-182.


Why Does Infection With Some Helminths Cause Cancer?

Brindley PJ, Costa JMCD, Sripa B.

Trends Cancer. 2015 Nov;1(3):174-182. doi: 10.1016/j.trecan.2015.08.011. Epub 2015 Sep 12. Review.


Susceptibility of Snails to Infection with Schistosomes is influenced by Temperature and Expression of Heat Shock Proteins.

Knight M, Elhelu O, Smith M, Haugen B, Miller A, Raghavan N, Wellman C, Cousin C, Dixon F, Mann V, Rinaldi G, Ittiprasert W, Brindley PJ.

Epidemiology (Sunnyvale). 2015 Jun;5(2). pii: 189. Epub 2015 Jun 21.


Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia.

Smout MJ, Sotillo J, Laha T, Papatpremsiri A, Rinaldi G, Pimenta RN, Chan LY, Johnson MS, Turnbull L, Whitchurch CB, Giacomin PR, Moran CS, Golledge J, Daly N, Sripa B, Mulvenna JP, Brindley PJ, Loukas A.

PLoS Pathog. 2015 Oct 20;11(10):e1005209. doi: 10.1371/journal.ppat.1005209. eCollection 2015 Oct.


Profiling miRNAs in nasopharyngeal carcinoma FFPE tissue by microarray and Next Generation Sequencing.

Peng J, Feng Y, Rinaldi G, Levine P, Easley S, Martinez E, Hashmi S, Sadeghi N, Brindley PJ, Mulvenna JP, Bethony JM, Plieskatt JL.

Genom Data. 2014 Aug 27;2:285-9. doi: 10.1016/j.gdata.2014.08.005. eCollection 2014 Dec.


The miRNAome of Opisthorchis viverrini induced intrahepatic cholangiocarcinoma.

Peng J, Feng Y, Rinaldi G, Yonglitthipagon P, Easley SE, Laha T, Pairojkul C, Bhudhisawasdi V, Sripa B, Brindley PJ, Mulvenna JP, Bethony JM, Plieskatt JL.

Genom Data. 2014 Aug 28;2:274-9. doi: 10.1016/j.gdata.2014.08.007. eCollection 2014 Dec.

Supplemental Content

Loading ...
Support Center